AUCTORES
Review Article | DOI: https://doi.org/10.31579/2637-8914/008
1 Department of Food Science and Nutrition, Manasagangothri, University of Mysore, Mysore. India.
*Corresponding Author: Jamuna Prakash, Department of Food Science and Nutrition, Manasagangothri, University of Mysore, Mysore. India.
Citation: Prabhavathi S.N and Jamuna Prakash (2019) Efficacy of Monosodium Glutamate as A Flavour Potentiator in Salt Reduction: a Review. J.Nutrition and Food Processing, 2(1); Doi:10.31579/2637-8914/008
Copyright: © 2019. Jamuna Prakash .This is an open-access article distributed under the terms of The Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Received: 03 August 2019 | Accepted: 14 August 2019 | Published: 20 August 2019
Keywords: flavor enhancer; sodium reduction; salt substitutes; glutamates; sensory profile; palatability
Sodium is an essential micro nutrient and an indispensable ingredient in most of the savoury foods. The salty taste is mainly contributed by sodium chloride through a proto-typical stimulus. The current sodium intake has been estimated to be exceeding normal recommendation at an alarming rate. This has given rise to health concerns since excessive sodium intake is associated with rise in blood pressure and eventually to cardiovascular diseases. The habitual salt intake among Asian population is around 10-12g/day against the WHO recommendation of 5-6g/day. Today food processing industries are facing challenges pertaining to sodium reduction, since it reduces the overall acceptability. In any food sodium can be reduced through a gradual lowering of salt level, however, this would require several months since it also decreases the overall palatability of foods. Another strategy that can be adopted to overcome this problem is to employ salt substitutes like monosodium glutamate (MSG). MSG has 30% less sodium in comparison to table salt and can help maintain palatability of foods. There are many studies supporting this observation. Our studies on the acceptability profile of salt reduced MSG incorporated fried preparations showed that approximately 25% of salt could be reduced in products without any significant effect on flavor profile. The results indicated that spice added product could be consumed with lower sodium levels and MSG had synergistic effect with spices. In salt reduced tomato soups, the control product with low salt was given lower scores as against MSG incorporated samples. It was also observed that increasing levels of MSG resulted in higher acceptance of products. Hence, it can be said that using MSG as a substitute would be a better option for maintaining adequate palatability in savoury foods with reduced sodium content.
Sodium chloride is considered as an indispensable ingredient in most of the processed savoury products. The salty taste contributed by sodium chloride is a prototypical stimulus [1]. Sodium is known to improve various sensory properties of food; mainly by increasing saltiness and sweetness, decreasing bitterness and also bringing about other congruent flavor effects [2]. The overall liking and acceptance of salty foods and their governing factors are not well understood. Certain environmental factors like, level of sodium in diet and sodium content in habitual diet are proposed to have a significant role [3, 4]. Sodium is an essential element needed for maintaining normal physiological functions. The estimated current sodium intake of populations across the world seems to be exceeding the normal recommendation [5] and is not showing any decline. This has raised concerns regarding the safety of consumers since high sodium intake is strongly associated with an increase in blood pressure. Apart from this, it is also known to have other negative health effects such as gastric cancer and decreased bone mineral density [6].
It has been reported that a modest 15% reduction in sodium intake can prevent cardiovascular disease related deaths all over the world over in 10 years [7]. Despite its negative health consequences, humans are still continuing to consume sodium in the form of salt in amounts well above the recommended levels in most of the developed countries. Hence, this should become the prime priority for public health and well being. Due to this, a wide variety of strategies to reduce sodium in different food matrices have been tried. However, success is said to be often very limited since, sodium reduction tends to have adverse effects both on taste quality as well as flavor perception [8]. As per World Health Organization (WHO) recommendation, an adult individual is permitted to consume <5g>
Concenrns for Food Industry With Reference to Sodium Reduction
Sodium chloride is one of the most commonly used food additives, because it is low cost and has the ability to increase one’s liking of foods via bringing about modification in flavor and other functional parameters in a food matrix [11,12]. Sodium chloride is indispensable in food processing. It is normally added to achieve technological properties such as dough development in bread and it also helps to bind water in meats. Thus, it helps to preserve the products. It has been reported that the sodium content of many food products exceeds the maximum set limits and such levels are thought to produce positive sensory effects [13]. A survey was carried out in UK among the food manufacturers to collect responses regarding the usage of sodium chloride in a wide variety of processed foods. The commonly cited response was that salt imparts appetizing flavor and the constraint to reduce sodium content in food was that it is known to greatly affect the palatability and consumer preference [14]. As sodium reduction is known to reduce food acceptability, it would increase the pressure on the food manufacturers to maintain and retain current sodium levels in processed foods. Sodium reduction in a food matrix is known to have greater impact on the overall taste perception. The major areas of concern include the following aspects.
1. Loss of Palatability and Reduced Consumer Acceptance
In a food choice taste is considered as the major governing factor. Humans and animals are known to have liking towards salty taste [15]. Therefore, when there is a greater reduction in the level of salt, consumer acceptance would tend to decline [16, 17]. A gradual small incremental decrease in the amount of added sodium is thought to be effective since consumers may not be able to detect the level of reduction up to certain point [18]. A continued reduction in the amount of sodium added to a food product inevitably leads to a saturation point at which a difference in flavor profile would reach a detectable level and the resultant effect is reduced food acceptability. Investigation by Lukas et al. [19] demonstrated that sodium reduction in a meal component to the extent of >50% was found to have only a minor decrease in liking. Thus, a large amount of sodium reduction could be achieved. But, the salty taste of sodium needs to be replaced with a suitable substance in order to have positive consumer acceptance.
2. Textural and other Quality Characteristics
Reducing sodium chloride level has been demonstrated to negatively affect the textural parameter along with affecting other parameters including moisture level, fat content, pH, starter culture, various additives and even processing conditions [1]. For instance, sodium chloride helps to bind the food constituents such as proteins, fats and even water. Therefore, the meat batters containing low sodium need to incorporate a sodium replacer. This not only helps to achieve salty taste, but also helps to compensate for other functional roles which might be lost when there is low sodium content in a food matrix [20]. Sodium chloride helps to inhibit the growth of yeasts. It also facilitates the development of gluten structure in bread. Therefore, when there is a reduction in the level of sodium chloride, it would increase the risk of rapid spoilage through the growth of yeast colonies and could also affect gluten development which is known to have negative effect on the texture of bread [21]. In cheese preparation if the sodium content is reduced, it could affect the starter culture activity. In US, the food industries are marketing cheddar cheeses with different levels of sodium chloride [22].
3. Food Preservation and Microbial Safety
Sodium helps to reduce the water activity and thus limits the growth of pathogens and spoilage microorganisms in a wide variety of food system [23]. Sodium chloride is widely used in meat industry both as a preservative and for palatability, though consumers are now gradually becoming aware of adverse effects of excessive salt consumption [24]. In processed meat products and cheeses, sodium chloride is known to minimize the growth and production of toxin especially by C. Botulinum [25], and others such as sodium diacetate also show similar effect for Listeria monocytogenes and lactic acid bacteria in ready-to-eat meats [26]. On the other hand, sodium reduction would tend to increase the growth of bacteria and bring down the shelf life. When sodium is reduced certain factors such as cooking, packaging and storage temperature should be given utmost importance. Other preservatives need to be added to extend the shelf life. All low sodium products need to be evaluated for its microbiological safety and shelf stability as these qualities are greatly associated with adverse effects on the stored products in low sodium environment [23].
Use of Salt Substitutes
Due to the adverse effect of high sodium consumption on health, it has become imperative to use a suitable alternative that can compensate for the salty taste along with maintaining normal sensory attributes. The food processing industries have resorted to use salt substitutes to maintain normal sensory attributes of savoury foods. These salt substitutes mimic the pure taste of saltiness and can be incorporated to foods with an objective of maintaining the savoury taste. Sodium chloride replacers such as potassium chloride, calcium chloride and magnesium sulphate are being used to replace or enhance salty taste in a range of food products [27]. These salts, though they are beneficial in contributing salty taste, may also bring about certain undesirable effects such as bitter after-taste, metallic or astringent tastes. Due to this, their use is currently limited in various food manufacturing sectors [28, 29]. Food grade acids have also been shown to be effective in enhancing the saltiness of sodium. Little and Brinner [30] conducted an evaluation of the sodium chloride and citric acid content of tomato soup to know the taste preference and saltiness. It was observed that, the intensity of saltiness increased along with an increase in citric acid concentration.
The other viable solution to improve the sensory profile of low sodium products would be to incorporate certain flavouring agents such as herbs and spices and flavour potentiating agents. One of the most important flavor potentiating agents is monosodium glutamate (MSG) which is responsible for contributing umami flavor and has been proven to be a good flavor enhancer especially in low sodium chloride products. MSG is known to contain only 12% of sodium which is comparatively lower than common table salt and its incorporation would help to achieve normal salty taste perception along with maintaining normal sensory attributes without leading to substantial increase in total sodium content of the product [11].
Research Studies on The Sensory Aspects of MSG Incorporated Salt Reduced Products
The preferred level of salt in any food product can be lowered through a reduction in sodium intake. This should be exercised gradually. Since a sudden reduction would tend to have initially a decreased palatability. This attempt may take several months of effort to accustom to low salt profile of the products. Available evidence suggests that low sodium foods would be more acceptable when prepared by adding acids and other flavouring ingredients in comparison to foods made without adding acid or any flavouring agents. It is also known to cause acquisition of a preference for the newly formulated foods [31]. MSG is known to alter the flavor profiles through which it brings about enhanced palatability.
The above studies imply that MSG is the most suitable salt replacer with a great potential to maintain the pleasantness, saltiness, familiarity and taste intensity of various products. Hence, with low sodium chloride it would be possible to achieve greater level of consumer acceptability without substantially adding up to increased sodium consumption. Thus, the prevailing problem associated with high sodium intake could be minimized.
Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. Auctoresonline publishing platform can be used to facilitate of optimal client-based services and should be added to health care professionals' repertoire of evidence-based health care resources.
Journal of Clinical Cardiology and Cardiovascular Intervention The submission and review process was adequate. However I think that the publication total value should have been enlightened in early fases. Thank you for all.
Journal of Women Health Care and Issues By the present mail, I want to say thank to you and tour colleagues for facilitating my published article. Specially thank you for the peer review process, support from the editorial office. I appreciate positively the quality of your journal.
Journal of Clinical Research and Reports I would be very delighted to submit my testimonial regarding the reviewer board and the editorial office. The reviewer board were accurate and helpful regarding any modifications for my manuscript. And the editorial office were very helpful and supportive in contacting and monitoring with any update and offering help. It was my pleasure to contribute with your promising Journal and I am looking forward for more collaboration.
We would like to thank the Journal of Thoracic Disease and Cardiothoracic Surgery because of the services they provided us for our articles. The peer-review process was done in a very excellent time manner, and the opinions of the reviewers helped us to improve our manuscript further. The editorial office had an outstanding correspondence with us and guided us in many ways. During a hard time of the pandemic that is affecting every one of us tremendously, the editorial office helped us make everything easier for publishing scientific work. Hope for a more scientific relationship with your Journal.
The peer-review process which consisted high quality queries on the paper. I did answer six reviewers’ questions and comments before the paper was accepted. The support from the editorial office is excellent.
Journal of Neuroscience and Neurological Surgery. I had the experience of publishing a research article recently. The whole process was simple from submission to publication. The reviewers made specific and valuable recommendations and corrections that improved the quality of my publication. I strongly recommend this Journal.
Dr. Katarzyna Byczkowska My testimonial covering: "The peer review process is quick and effective. The support from the editorial office is very professional and friendly. Quality of the Clinical Cardiology and Cardiovascular Interventions is scientific and publishes ground-breaking research on cardiology that is useful for other professionals in the field.
Thank you most sincerely, with regard to the support you have given in relation to the reviewing process and the processing of my article entitled "Large Cell Neuroendocrine Carcinoma of The Prostate Gland: A Review and Update" for publication in your esteemed Journal, Journal of Cancer Research and Cellular Therapeutics". The editorial team has been very supportive.
Testimony of Journal of Clinical Otorhinolaryngology: work with your Reviews has been a educational and constructive experience. The editorial office were very helpful and supportive. It was a pleasure to contribute to your Journal.
Dr. Bernard Terkimbi Utoo, I am happy to publish my scientific work in Journal of Women Health Care and Issues (JWHCI). The manuscript submission was seamless and peer review process was top notch. I was amazed that 4 reviewers worked on the manuscript which made it a highly technical, standard and excellent quality paper. I appreciate the format and consideration for the APC as well as the speed of publication. It is my pleasure to continue with this scientific relationship with the esteem JWHCI.
This is an acknowledgment for peer reviewers, editorial board of Journal of Clinical Research and Reports. They show a lot of consideration for us as publishers for our research article “Evaluation of the different factors associated with side effects of COVID-19 vaccination on medical students, Mutah university, Al-Karak, Jordan”, in a very professional and easy way. This journal is one of outstanding medical journal.
Dear Hao Jiang, to Journal of Nutrition and Food Processing We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.
As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.
Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.
International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.
Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.
Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.
I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!
"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".
I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.
We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.
I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.
I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.
I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.
Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.
“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.
Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.
The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.
Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.
My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.
My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.