AUCTORES
Review Article | DOI: https://doi.org/10.31579/2637-8914/046
* Department of Food Process Engineering, College of Engineering and Technology, Wolkite University, Wolkite, Ethiopia.
*Corresponding Author: Gashaw Abebaw, Department of Food Process Engineering, College of Engineering and Technology, Wolkite University, Wolkite, Ethiopia.
Citation: Gashaw Abebaw (2021) Review on Structure, Functional and Nutritional Composition of Barley (Hordeum vulgare). J. Nutrition and Food Processing, 4(2); DOI:10.31579/2637-8914/046
Copyright: © 2021 Gashaw Abebaw, This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 22 March 2021 | Accepted: 29 March 2021 | Published: 05 April 2021
Keywords: grain; functional; composition; barley; animal feed; beer; nutritional components
Barley is a resilient plant, tolerant of a range of conditions, which may have been cultivated since 15 000 BC (Fast & Caldwell, 2000). Cultivated barley, Hordeum vulgare, is mainly grown for animal feed, especially for pigs, for malting and brewing in the manufacture of beer, and distilling in whisky manufacture. A small amount of barley is used for food. Barley is one of the leading grain crops produced in the world with growing worldwide recognized as a source of food and many valuable nutritional components that enrich the human diet. Barley grain is used primarily for malting and livestock feeding, and the straw is also an important feedstuff when more desirable forages are not available
Barley is a resilient plant, tolerant of a range of conditions, which may have been cultivated since 15 000 BC [1]. Cultivated barley, Hordeum vulgare, is mainly grown for animal feed, especially for pigs, for malting and brewing in the manufacture of beer, and distilling in whisky manufacture. A small amount of barley is used for food. Pearled barley is eaten in soups and stews in the UK and the Far and Middle East; barley is also used in bread (as flour) and ground as porridge in some countries [2]. The barley head or spike is made up of spikelets, which are attached to the rachis in an alternating pattern. The outer layers of the barley kernel consist of a husk, completely covering the grain; the pericarp (to which the husk is tightly joined in most species); the testa or seed coat, and the aleurone. Barley (Hordeum vulgare) is a very important grain in the world today and it ranks the fourth in both quantities produced and in area of cultivation of cereal crops in the world. The annual world harvest of barley in the late century was approximately 140 million tonnes from about 55 million hectares. It is very versatile in every way and has been well adapted through its evolution. It is the most adaptable of the cereals. Much of the world’s barley is produced outside of the regions where cereals such as maize and rice can grow well. It extends into the arctic or subarctic. Some species approach the subtropical Zone. Hordeum species are found in most areas with a Mediterranean climate. The genus is also represented in zones with an oceanic as well as a continental climate [3]. Barley also has a very good resistance to dry heat compared to other small grains. This feature allows it to grow near-desert areas such as North Africa. Barley is a cereal that belongs to the grass family Poaceae. There are three types of barley:
i) Hordeum vulgare: a six-rowed type of barley that has a spike notched on opposite sides with three spikelets on each notch. At each notch there is a flower or floret that later develops into a kernel;
ii) Hordeum distichum: a two-rowed type of barley that has central florets producing kernels and it has lateral florets that are sterile; and
iii) Hordeum irregular: the least cultivated, with fertile central florets and varying proportions of fertile and sterile lateral florets [4]
Barley (Hordeum vulgare) is one of the cereals which tolerate rather well abiotic stress conditions. Growers driven by the market demands tend to cultivate wheat even in areas that are more suited for the barley; such areas can, however, easily be brought again under barley. Although the area under barley and wheat can be interchanged, on an overall basis, the area under barley cultivation is governed by a wide range of other factors like demand from consumers or market price. Barley was the staple food of people in many countries for ages, but it drew away from favor due to changes in food preferences. Barley is now again returning to favor as it is considered the best food for health by nutritionists [5].
1. Distribution And Production Of Barley
1.1 Production of Barley
Barley is one of the leading grain crops produced in the world with growing worldwide recognized as a source of food and many valuable nutritional components that enrich the human diet. Barley grain is used primarily for malting and livestock feeding, and the straw is also an important feedstuff when more desirable forages are not available. Most barley is grown for malt due to the price premium [6]. Barley (Hordeum vulgare L.) is grown as a commercial crop in some one hundred countries worldwide and is one of the most important cereal crops in the world. Barley assumes the fourth position in total cereal production in the world after wheat, rice, and maize, each of which covers nearly 30% of the world’s total cereal production [7]. The Russian Federation, Canada, Germany, Ukraine, and France are the major barley producers accounting for nearly half of the total world production.
The annual production reached over 144 million tons in 2014, and the top producers in terms of production quantity are Russia, France, Germany, Australia, and Ukraine [7]. Barley has great adaptability to harsh environmental conditions and can thrive on marginal lands. It is cultivated across a wide range of production areas in the world such as at the high altitudes of the Himalayas and near the Arctic Circle [8]. Barley is one of the commonly grown food security crops in high altitude areas of CASCAPE intervention areas. The total number of households cultivating barley in the Amhara Region was estimated to be 1,391,000, while the total number of households cultivating barley at the national level was estimated to be 4,148,00 [9]. Similarly, the total number of households cultivating barley in South Gonder (in which Dera District is found) was estimated to be 182,750, while the total number of households cultivating barley in West Gojjam (in which Burie and Jabitehenan are found) was estimated to be 103,450 [10]. Its grain is used for the preparation of different foodstuffs, such as Injera, Kolo, and local alcoholic drinks, such as Tela. The straw is used as animal feed, especially during the dry season. The national area coverage of barley was estimated to be 1,047,000 ha with a productivity of 1.63 tons ha-1 while the regional area coverage and average productivity were estimated to be 328,000 ha and 1.3 tons ha-1, respectively [11]. Similarly, the total area coverage for South Gonder was estimated to be 35,861 ha with a productivity of 1.3 tons ha-1, while for West Gojjam 24,649 ha with a productivity of 1.1 tons ha-1. Among other factors contributing to the low productivity of the crop, the low yielding ability of farmers’ cultivars and soil acidity problems are the major bottlenecks.
Barley is regarded as a drought-tolerant crop which accounts for its popularity in areas receiving scanty rainfall. It is commonly grown in the semi-arid regions of North Africa, the Near- and Middle-East, South Asia, the Russian Federation, Eastern Asia, Europe, Australia, and the Andean countries of South America. Spring barley is cultivated in larger areas than winter barley because it is less risky. Winter barley is prone to damage from winter kill which affects the harvested yield. Furthermore, spring barley is preferred as a rotation crop with winter wheat as its short duration helps in fitting in the crop rotation very well. The production of barley between the decades 1970 to 2000 then fluctuated around 150 million tons with a little increase during the 1980s. Production has further decreased to around 140 million tons during 2000- 2007. European countries produce the bulk of barley. The USSR, now the Russian Federation, has produced the highest quantity of barley among all nations over the last fifty years
1.2 Classification of Barley
Barley is one of the most ancient crops cultivated already some 10 000 years ago. Barley cultivated for food and feed belongs to the species Hordeum vulgare L. [12]. Although the barley crop is distributed throughout the world, its supposed progenitor, Hordeum vulgare L. ssp. spontaneous C. Koch occurred in a more restricted area, namely the Middle East and adjacent regions of North Africa [13]. After domestication, unrecorded migration and trade would have rapidly distributed the barley crop outside the region of its origin. The result is the development of landraces adapted to northern and western European environments and later to North American, Australian, and Southern African environments [14]. Barley is well adapted to a wide range of environments. It is grown in different latitudes from the equator up to the 65th latitude in the north and the 50th latitude in the south as well as from sea level up to mountain slopes. Consequently, the list of agronomic criteria used in breeding consists of at least increased and stable yield, early flowering, and harvest, winter hardiness, resistance to extremes of temperature, edaphic factors and water stress, resistance to drought and soil acidity, salt tolerance, resistance to diseases and insect pests, and lodging. Quality criteria for breeding are determined according to the respective uses (processing characteristics and nutritional value) of barley. Extensive cultivation, intensive breeding, and selection have resulted in thousands of commercial varieties of barley. For commercial purposes, barley varieties are classified into broad classes that are used as a basis for world trade. The major factors used to distinguish barley varieties are feed or malting barley, winter or spring growth habit, 6-, 4- or 2-row varieties, covered or naked/hulled barley, and starch amylose/amylopectin ratio.
1.3 Common Usage and Nutritional Composition
1.3.1 Healthy Benefit of barley
Barley is a major cereal grain, commonly found in bread, beverages, and various cuisines of every culture. Whole grains are important sources of dietary fiber, vitamins, and minerals that are not found in refined or "enriched" grains. Refining grains removes the bran, germ, and most of their fiber and nutrients [15]. Barley has many economic uses today. Barley is produced primarily as animal feed. For example, over half of the barley grown in the United States is used for livestock feed. Barley as feed has the same nutritive value as corn. Barley is high in carbohydrates, with moderate amounts of protein, calcium, and phosphorus. It also has small amounts of B vitamins. The entire barley kernel is used as feed after it has been steamrolled or gone through a grinding process. By-products from the brewing process and malt sprouts are also used in livestock feed. It is found that two-rowed barley is most often used for animal feed because it produces higher weight and superior kernel production. Barley is also used in the production of beer and some wines. About 25% of the cultivated barley in the United States is used for malting, with about 80% being used in beer production, 14% used in distilled alcohol production, and 6% used for malt syrup, malted milk, and breakfast foods. A small amount of the produced barley is used for human food in the form of pearl barley or the form of flour for porridge. Sometimes barley is grown as a hay crop in some areas. Only the smooth varieties or awnless varieties are used in hay production. Winter barley also can be used for hay if pasteurized before the stems start to elongate. The amount of barley used for ethanol has been increased significantly in the last decade, especially in some EU countries [16].
Barley has been used to formulate various “healthy” food products such as pasta and bread [17]. The major component of barley kernel is starch that may amount to over 70% of the dry weight [18]. Therefore, it may be expected that the quality of barley-based food/feed products can be much affected by the starch properties. Starch is also a byproduct of the barley fractionation process for β-glucan production [18. Understanding the starch properties provide a basis for value-added processed products containing barley. Recently produced novel starches from genetic mutants such as the “amylose-only” genotype provide various possible applications for the food and other industries [19]. A systematic review of various aspects of the starch is needed to support the current exploitation of barley as a sustainable crop. Pearling reduces the contents of insoluble fiber, protein, ash, and free lipids, but increases the contents of starch and β-Glucan by the removal of outer layers, including the hull (palea and lemma), bran (pericarp, testa), and germ (embryo), which are richer in insoluble fiber, protein, ash, and lipids and poorer in starch and β -Glucan can than the endosperm (27, 28). Generally, hulled barley is preferred to hulless barley for malting and brewing because of the contribution of the hull to beer flavor and as a filtering aid during brewing. In addition to its robust flavor, barley's claim to nutritional fame is based on its being a very good source of dietary fiber and a good nutritional source of Iron, Calcium, Magnesium, Selenium, Copper, Boron, Zinc, Molybdenum, and a better source of Protein, Carbohydrates, and Lipids [20]. Barley is a good source of both soluble and insoluble dietary fibers and in particular, the beta-glucan. The beta-glucan content of cereals ranges from 1% in wheat grains, 3-7% in oats, and 5-11% in barley. Beta-glucan is principally found in the aleurone layer and endosperm in barley. Compared to insoluble fiber such as cellulose, beta-glucan is more flexible, soluble, and viscous. It confers many health benefits including reducing the risk of heart disease, lowering blood cholesterol levels, increasing insulin response in diabetics, and preventing obesity and cancer. There is an increasing interest in using beta-glucan from barley as a functional food ingredient. Barley's fiber can prevent several different conditions. For example, when barley's fiber binds to and removes cholesterol-containing bile, this can be very beneficial for people struggling with heart disease since it forces the body to make more bile by breaking down cholesterol, thus lowering cholesterol levels. According to the Archives of Internal Medicine confirms that eating high fiber foods, such as barley, helps prevent heart disease. People eating the dietary fiber, 21 grams per day, had 12% less coronary heart disease (CHD) and 11% less cardiovascular disease (CVD) compared to those eating the least, 5 grams daily. Those eating the most water-soluble dietary fiber fared even better with a 15% reduction in risk of CHD and a 10% risk reduction in CVD. The fiber in barley also helps to prevent blood sugar levels from rising too high in people with diabetes [21].
There is growing interest in using barley for food production due to its various health effects, such as lowering blood cholesterol, regulating glycemic index, and antioxidant activity (Baik and Ullrich 2008). Functional components of barley responsible for these health benefits include β-glucans, tools (such as tocotrienols and tocopherols), polyphenols (such as phenolic acids, proanthocyanidins, and catechins), and others [22]. Whole barley grain is mostly used for feeding animals. For food purposes, barley is mainly used as a de-hulled grain or high fiber content product. Food produced from barley is a good source for many nutrients such as protein, fiber, minerals, and B-vitamins. The fiber content of barley is high and rich in β-glucan that is mainly soluble. Fiber-rich cereals such as barley are beneficial for balancing the human diet in a manner that is of no relevance for animals. Low-digestible carbohydrates, especially β-glucan and resistant starch have a positive impact on lowering post-prandial blood glucose levels. Further, β-glucan has been reported to reduce blood cholesterol levels. Barley products are thought to be good for diabetics, obese and overweight people, and for those who have a high blood cholesterol level [23]. The β-glucan from barley is also known to stabilize digestion processes in young farm animals, especially in piglets [24]. However, due to its viscosity-enhancing property, β-glucan causes undesirable effects in the digestive tract especially of young avians. But with the increasing age of the birds the ant nutritive effect decreases [25]. The β-glucan levels are shown in Table 6. Although barley has a relatively high protein content, it does not have the same baking characteristics as wheat gluten. Therefore, typical barley bread has low bread volumes. Barley flour is primarily used in combination with other flours to make multigrain bread. The production of barley is presented in Table 1, the proximate composition in Table 2, and the chemical composition in Table 3. The starchy endosperm consists of food reserves in the form of highly digestible carbohydrates (mainly starch), whereas the bran contains high levels of fiber and comparatively more minerals and fat than the endosperm.
Chemical Composition of Barley Grain
The barley grain consists of (19, 31) - Starch - 65-68% Protein - 10-13.6% β -Glucan - 4-9% Lipids - 2-3% Minerals - 1.5-2.5% Total dietary fiber - 11-34% Soluble dietary fiber - 3-20% ( Nutrition Data 2009)
Embryo
A covering that botanists called the integument covers the female ovule in a barley plant. When an egg cell from a barley ovule unites with a sperm cell, it forms a zygote, containing genes from both parent plants. The zygotes grow into a seed embryo. The integument covering the ovule becomes the covering of the barley seed. Many seeds remain dormant or have other conditions, under which the seeds germinate, the process by which a plant emerges from an embryo. Barley seeds do not have a special period of dormancy. When they have water and warm temperature, they germinate.
Endosperm
The protective layer of endosperm tissue surrounds the embryo, which rests in a special sac. The endosperm collects fats, protein, and starch for the growing embryo.
Gibberellic Acid
The seed absorbs water through a process called imbibitions. The water moves a hormone called Gibberellic acid to the aleurone cells, which are proteins in the endosperm. The Gibberellic hormone activates the DNA coding for amylase, an enzyme that turns the starch in the endosperm into maltose, a sugar that the embryo needs for nutrition. This is the malt sugar that is the necessary ingredient for making beer, giving it its distinctive flavor. The protein-rich aleurone layer of the endosperm is what makes barley, brown rice, and other grains “chewy.”
Seed Growth
The amylase is shipped into the embryo by the endoplasmic reticulum, usually abbreviated ER. The amylase goes to the Golgi, a sac-like, flattened, layered organ near the nucleus of the barley seed embryo. The Golgi load proteins and carbohydrates into vesicles or bubbles bound by membranes for transport to the growing plant cells.
The Radicle
The radicle is the first part of the barley plant to emerge from the seed. Fueled by sugar carried by the vesicles, the new plant grows larger.
1.3.2 Detailed nutritional composition
Moisture content
The moisture content is considered one of the most important quality criteria of malting barley. Wet barley respires more rapidly than dry barley, which may lead to a rise in temperature. High temperature and humidity may then activate the growth of bacteria and fungi, and lead to germination losses and production of mycotoxins. Safe storage conditions are a moisture level of 10-12% and a temperature of 15 o C (Briggs, 2001). To avoid spoilage, immediate drying of barley after harvesting is needed.
Carbohydrates
Carbohydrates constitute the bulk of the total dry matter of the barley grain. Most of the carbohydrate in barley is starch which serves as an energy source during germination. Over 96% of the total grain cellulose is present in the hulls (husks) [26]. Mono- and di-saccharides (sucrose, glucose, fructose, and maltose) are present in lesser amounts, but their concentration is twice as high as in other cereals. Of the non-starch polysaccharide fraction the content of arabinoxylan (total 6.7% of which 0.4% is water-soluble; [27] and β-glucan (4.6% is of relevance when barley is fed to young monogastric, due to the negative effects on digestion. It is noteworthy that contrary to this, the low-digestible carbohydrates especially β-glucan and resistant starch have a positive impact on human health due to their role in lowering post-prandial blood glucose levels and in reducing the blood cholesterol level [28].
Proteins
The proteins of barley can be divided into four solubility groups: albumins (water-soluble); globulins (soluble in dilute saline); prolamins (soluble in alcohol/water mixtures); and glutelins (soluble only in dilute acid or alkali). Prolamins, called hordeins in barley, are the major storage proteins and account for 35 to 50% of the total nitrogen in the grain. The albumins, globulins, glutelins consist predominantly of structural and metabolic proteins [29]. The protein content of barley grains varies considerably. The precise composition depends on the growth conditions and the rate and timing of nitrogen fertilization [30]. For this reason, an appropriate comparator must be used for the comparative analysis. In general, the protein content and protein quality of barley grain are not sufficient for high-performing monogastric farm animals. Consequently, their diets have to be supplemented with other protein sources. The low content of the consequence of the high content of hordeins is relatively low in these amino acids. The amino acid composition of crude protein in barley grain fractions [31]. Hordeins have been reported to interfere with the brewing process; the amount of extract that ultimately can be derived from the malt is inversely related to the protein (hordein) content of the original grain.
Vitamins
The vitamin content of barley grains varies widely. Un-germinated barley does not contain vitamins A, C, and D, although the carotenoids and sterols that are present may act as precursors for vitamins A and D, respectively [32]. Vitamin E, a mixture of tocopherols, occurs in barley oil. Barley is unique among cereals in having all eight naturally occurring tocopherols. The tocopherols are found exclusively in germ tissue (embryo, scutellum) and tocotrienols in the starchy endosperm and aleurone [33]. Barley also contains B vitamins. These vitamins are mainly present in the embryo and the aleurone layer [34]. Typical ranges of B vitamin and folate concentrations in barley.
Minerals
The major constituents of the mineral fraction of barley are magnesium, phosphorus, potassium, calcium, and sodium. The average mineral content varies significantly, and this appears to be due to several factors, including the variety in question, the growing and soil conditions, and fertilizer application. Major constituents based on a compilation of worldwide. A high portion of phosphorus in barley grain is bound to the phytate complex (51-66%) making much of the phosphorous unavailable to monogastric animals. Yet barley contains MOR [35] phosphorous than common cereal grains and the phosphorous bioavailability of barley is higher than that in other grains [36]. The amounts of copper, iron, manganese, and zinc present in barley grain may vary to a large extent due to growing conditions and this has to be taken into account when diets for farm animals are formulated [37]. As with vitamins, these minerals are mainly concentrated in the embryo and the aleurone layer (Duffus and Cochrane.
Lipids
In the mature barley grain, the lipid content is approximately 3%. Lipids constitute only a small part of the dry matter in most barley tissues yet they comprise significant reserves in the embryo and the aleurone layer of the grain. They are essential for the functional integrity of the cells. The composition and distribution of lipids in the different parts of barley grain are presented.
Amino acid
The amino acid composition of barley protein is quite similar to the other cereal grains. High glutamic acid and proline contents and relatively low amounts of basic amino acids characterize the barley grain. The average amino acid composition of typical hulled and hull-less barley. As with most nutrients in barley, other than fiber, removal of the hull has the effect of increasing the protein and amino acid levels in the remainder of the kernel. In particular, hulled barley protein is slightly higher in lysine than that of hull-less barley. Table (4,5,6)
Antioxidants
Barley contains a group of natural antioxidants called flavonoids. In general, cereals have only a small amount of flavonoids, except the barley grains contain measurable amounts of catechin (the same antioxidants found in green tea). Flavonoids as powerful antioxidants have anti-cancer, anti-allergic, anti-inflammatory, anti-carcinogenic, and gastroprotective properties. Besides flavonoids, barley also contains another group of antioxidants called Tools (vitamin E, the same antioxidants found in carrots). The main source of tools in our diet are vegetable oils, but a substantial amount of them are also present in barley. Toxicol content of barley confers many health benefits such as modulating degenerative diseases, cardiovascular diseases, and lowering blood cholesterols. The most active form of tool is alpha-tocopherols which show the ability to decrease lipid oxidation, platelet aggregation, and inflammation.
The main source of tools in our diet are vegetable oils, but a substantial amount of them are also present in barley. Toxicol content of barley confers many health benefits such as modulating degenerative diseases, cardiovascular diseases, and lowering blood cholesterols. The most active form of tool is alpha-tocopherols which show the ability to decrease lipid oxidation, platelet aggregation, and inflammation.
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Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.
“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.
Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.
The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.
Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.
My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.
My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.