Multisystem Diseases in Clinical Practice: Diagnosis, Management, and Patient Outcomes in Complex and Multimorbid Patients

Deadline for manuscript submissions: 15 Oct 2026 | Viewed by 86
Impact Factor: 2.66 | Citiescore: 2.1

Special Issue Editors

Nikolaos A Chrysanthakopoulos
Department of Pathological Anatomy, Medical School, National and Kapodistrian University of Athens , Greece,+30-2610-225288
Interests: Periodontology, oral oncology, and preventive dentistry. Key interests include the diagnosis, treatment, and management of periodontal diseases and oral cancers. Additional focus is on strategies to promote oral health and prevent dental and systemic complications.

nikolaos_c@hotmail.com

Special Issue Information

Dear Colleagues,

The growing prevalence of multisystem diseases and multimorbidity presents a significant challenge in modern clinical practice. Patients with complex conditions often require comprehensive diagnostic approaches and coordinated management strategies that address multiple organ systems simultaneously.

Advances in clinical diagnostics, imaging technologies, and integrated care models have improved the identification and management of multisystem disorders. The increasing use of digital health tools, electronic health records, and artificial intelligence (AI) is enhancing clinical decision-making and enabling more personalized and efficient patient care.

Despite these developments, managing patients with multiple coexisting conditions remains challenging due to disease interactions, polypharmacy, and variability in patient outcomes. A multidisciplinary approach involving coordinated care and patient-centered strategies is essential to improve clinical outcomes and quality of life.

This Special Issue aims to bring together cutting-edge research and comprehensive reviews focusing on the diagnosis, management, and outcomes of multisystem diseases in complex and multimorbid patients. We welcome contributions that explore clinical innovations, integrated care approaches, and strategies to optimize patient outcomes.

Nikolaos A Chrysanthakopoulos
Guest Editor

 

Manuscript Submission Information

Manuscripts should be submitted through the journal’s online submission system by registering and logging in. Once registered, authors can proceed with the submission process. Submissions will be accepted until the specified deadline.

All manuscripts that pass initial editorial screening will undergo a rigorous single-blind peer-review process. Accepted papers will be published online promptly and included within the Special Issue.

We invite original research articles, review articles, and short communications. Authors planning submissions may send a tentative title and a short abstract (approximately 250 words) to the Editorial Office for preliminary evaluation.

Submitted manuscripts must be original and not under consideration elsewhere (except conference proceedings). Authors should follow the Instructions for Authors to ensure proper formatting and compliance with journal standards.

As an open-access journal, an Article Processing Charge (APC) may apply upon acceptance. Authors are encouraged to ensure high-quality English; professional editing services may be used if needed.

Keywords

  • Multisystem Diseases
  • Multimorbidity
  • Complex Patients
  • Clinical Management
  • Integrated Care
  • Polypharmacy
  • Patient Outcomes
  • Chronic Conditions
  • Healthcare Coordination
  • Personalized Care

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Published Papers

Coming Soon

Dear Editorial Team, Clinical Medical Reviews and Reports. My experience with the journal was highly positive. The peer-review process was rigorous, constructive, and completed in a timely manner. The reviewers provided valuable comments that helped improve the quality and clarity of our manuscript. The editorial office was professional, responsive, and supportive throughout all stages of the publication process. Communication was clear and efficient, and any questions were addressed promptly. Overall, I found the journal to maintain high scientific standards and an excellent publication workflow. I would be pleased to consider submitting future work to this journal. Best wishes from, Elena Popa.

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Dr Elena Popa

It was my pleasure to submit my testimonial concerning the Reviewer Board of our Scientific Journal “Brain and Neurological Disorders”. The Reviewers focused on some modifications and their contribution was helpful. The ladies of our Editorial Office were also supported my efforts. It was my honor to have such a co-operation and I am looking forward for more collaboration.

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Dr Nikolaos Andreas Chrysanthakopoulos

Dear Grace Pierce, Editorial Coordinator of Journal of Clinical Research and Reports, Thank you for the speedy and efficient peer review process. I appreciate the fact that your peer reviewers do not take months to respond like with some other journals. I would also like to thank the editorial office for responding quickly to my questions. It is an excellent journal. I plan to submit more manuscripts in the future. Best wishes from, Robert W. McGee

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Robert W McGee

Dear Grace Pierce, Editorial Coordinator of Journal of Clinical Research and Reports, Working with you and your team on our recent publication in JCRR has been a truly wonderful and enjoyable experience. The responses were prompt, and the reviewers were patient, constructive, and highly professional. One reviewer in particular gave me the feeling that a professor was carefully reading and commenting on my coursework, which was deeply touching. The entire process was straightforward and hassle‑free, with no tedious online forms to complete. I highly recommend this journal. Best wishes from, DR Aibing Rao, Head of R&D

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Aibing Rao

I Appreciate the Opportunity to Share my Experience with the Journal of Clinical Research and Reports. The peer review process was timely and constructive, and the feedback provided helped improve the quality of our manuscript. The editorial office was professional, responsive, and supportive throughout the process, ensuring smooth communication and efficient handling of the submission. Overall, it was a positive experience collaborating with your team.

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Kashani Mehdi

Dear Mercy Grace, Editorial Coordinator of Obstetrics Gynecology and Reproductive Sciences, We would like to express our gratitude for your help at all stages of publishing and editing the article. The editors of the magazine answer all the necessary questions and help at every stage. We will definitely continue to cooperate and publish other works in the Obstetrics Gynecology and Reproductive Sciences! Best wishes from, Alla Konstantinovna Politova,

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Alla Konstantinovna Politova