AUCTORES
Globalize your Research
Review Article
*Corresponding Author: Aamir Jalal Al Mosawi, Advisor in Pediatrics and Pediatric Psychiatry, Headquarter of Copernicus Scientists International Panel Baghdad, Iraq.
Citation: Aamir Jalal A M. (2021). Review Article: The use of fenugreek supplementation in diabetes. Biomedical Research and Clinical Reviews. 4(4); DOI: 10.31579/2692-9406/076
Copyright: ©2021 Aamir Jalal Al Mosawi, This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Received: 27 July 2021 | Accepted: 11 August 2021 | Published: 19 August 2021
Keywords: fenugreek; diabetes; research findings
Dietary health supplements have increasingly used in the prevention and treatment of chronic disorders. During the previous decades, fenugreek (Trigonella foenum-graecum) seeds have been reported to have hypoglycemic and cholesterol lowering effects when used in type 1 and type 2 diabetes mellitus patients, and in experimental diabetic animals. The aim of this paper is to review fenugreek research findings relevant to its use in diabetes.
There is convincing research evidence suggesting that fenugreek can improve hyperglycemia and has a protective effective against diabetic complications through immunomodulatory, insulin stimulation, and antioxidant effects, enhancing adipocyte differentiation, inhibition of inflammation in adipose tissues, and preventing or lessening pancreatic and renal damage. Many of the beneficial effects of fenugreek in diabetes have been attributed to four bioactive components including diosgenin, 4-hydroxyisoleucine, furostanolic saponins, and the fiber in fenugreek.
During the 1970s and 1980s, several experimental researches on rats and dogs suggested that fenugreek (Trigonella foenum graecum seeds) has a hypoglycemic effect [1, 2, 3, 4].
The work of Madar et al (1988) suggested that fenugreek have the potential to be used in the treatment of non-insulin dependent diabetics, as they reported that the use of powdered fenugreek seed in a dose of 15 g soaked in water was associated with a marked decrease in the postprandial glucose levels [5].
Sharma and colleagues (1990) reported that the use of defatted fenugreek seed powder in the treatment of in type I diabetes, in a dose of 100 g divided in two doses for ten days, was associated with a considerable lowering of fasting blood sugar and resulted in an improvement in the glucose tolerance test. They also found a 54% lowering of 24-hour urinary glucose excretion. Treatment also had an important lowering effect on serum total cholesterol, LDL and VLDL cholesterol and triglycerides were also significantly reduced [6].
Khosla and colleagues (1995) reported an experimental study on rats which showed that oral fenugreek (2 and 8 g/kg dose) was associated with a considerable lowering (P < 0>
Sauvaire et al (1998) reported that 4-hydroxyisoleucine which is an amino acid extracted and purified from fenugreek seeds has an insulinotropic effect. 4-Hydroxyisoleucine augments glucose-induced insulin secretion from islets of Langerhans from rats and humans [8].
The experimental work of Broca et al (1998) on rats suggested that the antidiabetic effects of 4-hydroxyisoleucine on rats with non-insulin dependent diabetes result is partly attributed to a direct stimulation of the pancreatic B cell. They found that in non-insulin-dependent diabetic rats, a single intravenous administration of 4-hydroxyisoleucine in a dose of 50 mg/kg restored to some extent glucose-induced insulin response without affecting glucose tolerance. They also found that the subchronic intake of 4-hydroxyisoleucine. 50 mg/kg, daily lowered basal hyperglycemia, reduced basal insulinemia, and, improved glucose tolerance [9].
The experimental work of Raju et al (2001) on alloxan diabetic rats showed that fenugreek seed powder improves glucose homeostasis in tissues by reversing the abnormal glycolytic, gluconeogenic and lipogenic enzymes [10].
The experimental work of Anuradha and Ravikumar (2001) on rats showed that diabetic rats experience an increased lipid peroxidation and a higher susceptibility to oxidative stress associated with depletion of antioxidants in liver, kidney and pancreas. They reported that treatment with fenugreek seed powder normalized the antioxidant status [11].
Gupta et al (2001) reported a study which included 25 new cases of type 2 diabetes who had fasting glucose less 200 mg/dl. They treated twelve patients with hydro-alcoholic extract of fenugreek seeds 1 gm daily, and thirteen patients were treated with dietary control, exercise and placebo capsules for two months. The study showed that the addition of fenugreek seeds was associated with improved glycemic control and reduced insulin resistance in mild type-2 diabetic patients, and had a favorable effect on hypertriglyceridemia [12].
Puri and colleagues (2002) reported an experimental study on sub-diabetic and mild diabetic rabbits treated with fenugreek seeds in a dose of 50 mg/kg body weight for 15 days. Treatment was associated with a considerable lessening of the glucose tolerance curve and improvement in the glucose induced insulin response.
Puri and colleagues attributed the hypoglycemic effect to stimulation of insulin synthesis and/or secretion from the beta pancreatic cells of Langerhans.
Puri and colleagues also reported that treatment of five severely diabetic rabbits markedly reduced fasting blood glucose, but the reduction was not much correlated with the elevation of fasting serum insulin level, suggesting an extra-pancreatic effect [13].
The experimental work of Thakran et al (2004) alloxan diabetic rats suggested that treatment with fenugreek seed powder can reverse the diabetic state at the cellular level, help with the metabolic normalization, has a protective effect against the development of liver degenerative and nephropathic changes in diabetic rats [14].
Xue et al (2007) reported an experimental study on streptozotocin-induced diabetic rats which showed that fenugreek can reduce blood glucose, kidney /body weight ratio, blood lipids, and improve hemorheological properties when treatment repeated for six weeks [15].
Lu et al (2007) reported a clinical study which included sixty-nine patients with type 2 diabetes mellitus whose blood glucose levels were not adequately controlled by oral sulfonylureas hypoglycemic treatment. Forty six patients received fenugreek and 23 patients received placebo for 12 weeks. The addition of fenugreek to sulfonylureas hypoglycemic treatment was associated with reduction of blood glucose level and improved symptoms [16].
Kassaian et al (2009) reported the treatment of eighteen diabetic patients with fenugreek seeds powder10 grams daily. Eleven patients took fenugreek mixed in hot water and seven took it mixed with yoghurt for eight weeks. Fasting blood sugar, triglycerides, and VLDL-C were considerably (25 %, 30 % and 30.6 % respectively) only in patients who took fenugreek seed soaked in hot water [17].
Mowla et al (2009) reported an experimental study on alloxan-induced diabetic rats showed that treatment with fenugreek) seed extract 1g/kg /body weight has an effective hypoglycemic effect, and a high dose of 3g/kg/body weight was not associated with any toxicity [18].
Hamden et al (2010) reported and experimental study on rats with alloxan-induced diabetes who had pancreatic islet and beta-cells damage, low activities of superoxide dismutase, glutathione peroxidase, catalase, and reduced glutathione content in kidney.
Treatment with fenugreek oil was associated with marked improvement in blood glucose levels, glucose intolerance, and insulin sensitivity occurring in association with improvement in pancreatic and renal damage, and reduction of raised levels of lipid peroxidation, creatinine, albumin, and urea. The beneficial effects of fenugreek in this study were attributed to immunomodulatory, insulin stimulation and antioxidant effects [19].
Uemura T, et al (2010) reported and experimental study on diabetic obese KK-Ay mice which showed that fenugreek can improve diabetes by enhancing adipocyte differentiation and inhibiting inflammation in adipose tissues through the effects of diosgenin which is an aglycone [20].
Xue et al (2011) reported an experimental on rats with streptozotocin induced diabetic nephropathy who had reduced activities of superoxide dismutase and catalase, elevated levels of malondialdehyde in the serum and kidney, and elevated levels of 8-hydroxy-2-deoxyguanosine in renal cortex DNA and urine. Treatment with fenugreek restored these abnormalities in a dose-dependent manner. Treatment considerably improved all of the ultramorphological renal changes, including the uneven thickening of the glomerular base membrane. This experimental study showed that fenugreek has a protective effect against functional and morphological renal damage in diabetic rats mediated through enhancing antioxidants and inhibition of buildup of oxidized DNA in the kidney [21].
Puri and colleagues (2012) reported and experimental study on rabbits with alloxan-induced diabetes which showed that a compound GII purified from the water extract of fenugreek had an antidiabetic property [22].
Hamza et al (2012) reported an experimental study on mice which showed that fenugreek had a preventive and curative effect in type 2 diabetes induced by high-fat diet [23].
Gupta et al (2014) reported an experimental study on streptozotocin-induced diabetic rats that had marked increase in the expressions of retinal inflammatory tumor necrosis factor-α and interleukin-1β and angiogenic vascular endothelial growth factor and protein kinase C -β molecular biomarkers. The study showed that treatment with fenugreek 100 and 200 mg/kg body weight for 24 weeks was associated with significant inhibition in the expression of the elevated inflammatory and angiogenic molecular biomarkers. Fenugreek also had a positive modulatory effect on retinal oxidative stress, and prevented the development of retinal vascular leakage. This study suggested that fenugreek supplementation can help in preventing diabetes-induced retinal degeneration [24].
Neelakantan et al (2014) conducted a meta-analysis which included ten clinical trials and showed that fenugreek seeds had beneficial effects on glycemic control in diabetic patients [25].
Smith et al (2014) reviewed the research findings relevant to the use of dietary supplements lowering blood glucose, and found that the strongest research evidence was associated with alpha-lipoic acid and fenugreek [26].
Rawat et al (2014) reported an experimental study on high-fructose diet fed streptozotocin-induced diabetic rats which showed that 4-Hydroxyisoleucine isolated from fenugreek seeds improved insulin resistance by promoting mitochondrial biogenesis and acting through AMPK and Akt dependent pathway [27].
Gaddam et al (2015) reported a 3-year randomized, controlled, parallel clinical study which included pre-diabetic individuals. Sixty-six individuals were treated with fenugreek powder, 5 g twice a day before meals, and seventy-four individuals served as controls. Treatment was associated with considerable lowering of fasting plasma glucose, postprandial plasma glucose, and low density lipoprotein cholesterol, and marked increase in serum insulin. Controls had 4.2 times higher chance of developing diabetes compared to treated individuals. Treatment was not associated with adverse effects and the beneficial effect was attributed to reduction of insulin resistance [28].
Verma et al (2016) reported a placebo-controlled clinical study which included 154 patients with type 2 diabetes. 90-day treatment with Fenugreek extract, furostanolic saponins (Fenfuro) 500 mg twice daily was associated with marked lowering of fasting plasma and post-prandial blood sugar levels. More than 80% of the treated patients experienced reductions in fasting plasma sugar levels compared to 62% of patients who received placebo. 89% of the treated patients experienced a decrease in post-prandial plasma sugar levels compared to 72% of patients who received placebo. 48.8% of the treated patients reported lowering of anti-diabetic therapy dosage, while 18.05% of the patients who received placebo reported lowering of anti-diabetic therapy dosage. Treatment was not associated with adverse effects [29].
Geberemeskel et al (2019) reported a study which included 114 newly diagnosed uncomplicated type II diabetic patients. 57 patients received 25 g fenugreek seed powder solution orally twice a day for one month, and 57 patients received metformin. The study showed that fenugreek had marked effects in improving lipid metabolism in type II diabetes without the occurrence of adverse effects [30].
Hadi et al (2020) reported an 8-week controlled clinical study which included 50 patients with type 2 diabetes whom were treated with anti-diabetic drugs. The patients received either 5 g fenugreek seed powder, three times daily or served as control patients. Compared to the control patients, treated patients experienced a considerable lowering of fasting plasma glucose (p = 0.024) [31].
Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. Auctoresonline publishing platform can be used to facilitate of optimal client-based services and should be added to health care professionals' repertoire of evidence-based health care resources.
Journal of Clinical Cardiology and Cardiovascular Intervention The submission and review process was adequate. However I think that the publication total value should have been enlightened in early fases. Thank you for all.
Journal of Women Health Care and Issues By the present mail, I want to say thank to you and tour colleagues for facilitating my published article. Specially thank you for the peer review process, support from the editorial office. I appreciate positively the quality of your journal.
Journal of Clinical Research and Reports I would be very delighted to submit my testimonial regarding the reviewer board and the editorial office. The reviewer board were accurate and helpful regarding any modifications for my manuscript. And the editorial office were very helpful and supportive in contacting and monitoring with any update and offering help. It was my pleasure to contribute with your promising Journal and I am looking forward for more collaboration.
We would like to thank the Journal of Thoracic Disease and Cardiothoracic Surgery because of the services they provided us for our articles. The peer-review process was done in a very excellent time manner, and the opinions of the reviewers helped us to improve our manuscript further. The editorial office had an outstanding correspondence with us and guided us in many ways. During a hard time of the pandemic that is affecting every one of us tremendously, the editorial office helped us make everything easier for publishing scientific work. Hope for a more scientific relationship with your Journal.
The peer-review process which consisted high quality queries on the paper. I did answer six reviewers’ questions and comments before the paper was accepted. The support from the editorial office is excellent.
Journal of Neuroscience and Neurological Surgery. I had the experience of publishing a research article recently. The whole process was simple from submission to publication. The reviewers made specific and valuable recommendations and corrections that improved the quality of my publication. I strongly recommend this Journal.
Dr. Katarzyna Byczkowska My testimonial covering: "The peer review process is quick and effective. The support from the editorial office is very professional and friendly. Quality of the Clinical Cardiology and Cardiovascular Interventions is scientific and publishes ground-breaking research on cardiology that is useful for other professionals in the field.
Thank you most sincerely, with regard to the support you have given in relation to the reviewing process and the processing of my article entitled "Large Cell Neuroendocrine Carcinoma of The Prostate Gland: A Review and Update" for publication in your esteemed Journal, Journal of Cancer Research and Cellular Therapeutics". The editorial team has been very supportive.
Testimony of Journal of Clinical Otorhinolaryngology: work with your Reviews has been a educational and constructive experience. The editorial office were very helpful and supportive. It was a pleasure to contribute to your Journal.
Dr. Bernard Terkimbi Utoo, I am happy to publish my scientific work in Journal of Women Health Care and Issues (JWHCI). The manuscript submission was seamless and peer review process was top notch. I was amazed that 4 reviewers worked on the manuscript which made it a highly technical, standard and excellent quality paper. I appreciate the format and consideration for the APC as well as the speed of publication. It is my pleasure to continue with this scientific relationship with the esteem JWHCI.
This is an acknowledgment for peer reviewers, editorial board of Journal of Clinical Research and Reports. They show a lot of consideration for us as publishers for our research article “Evaluation of the different factors associated with side effects of COVID-19 vaccination on medical students, Mutah university, Al-Karak, Jordan”, in a very professional and easy way. This journal is one of outstanding medical journal.
Dear Hao Jiang, to Journal of Nutrition and Food Processing We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.
As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.
Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.
International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.
Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.
Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.
I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!
"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".
I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.
We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.
I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.
I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.
I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.
Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.
“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.
Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.
The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.
Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.
My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.
My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.
