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*Corresponding Author: Lázaro Martín Martínez Estupiñan, Specialist in Orthopedics and traumatology. Full Professor at the UCM-VC. General University Hospital Mártires del 9 de Abril. Villa Clara. Cuba.
Citation: Leonardo M. Aparicio, Martínez Estupiñan LM, Roberto M. Piñeiro, Gerardo C. Oliva, Sergio M. Piñeiro, (2024), Proposals for Modifications to The Mipo Surgical Technique in Diaphyseal Fractures of the Tibia, J. Clinical Orthopedics and Trauma Care, 6(1); DOI:10.31579/2694-0248/080
Copyright: © 2024, Lázaro Martín Martínez Estupiñan. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 08 January 2024 | Accepted: 16 January 2024 | Published: 24 January 2024
Keywords: minimal blade osteosynthesis; MIPO
There are multiple techniques for the treatment of tibia fractures, sometimes these techniques require a group of special accessories and instruments that allow the surgeon to carry out the procedure quickly and easily. Professionals make proposals for modifications, especially on instruments. After prioritizing in the group, seven modifications to the technique were proposed. Modifications to the MIPO technique may be another alternative in the therapeutic arsenal
There are multiple techniques for the treatment of tibia fractures, sometimes these techniques require a group of special accessories and instruments that allow the surgeon to carry out the procedure quickly and easily. Generally these accessories are expensive and the services do not have them. Fractures of the tibia have an incidence of 16.9/100,000 per year and between four and 23% are open injuries. Depending on the pattern of the fracture and the involvement of the soft tissues, they can be treated conservatively or surgically; However, there is no consensus for determining the optimal surgical technique. Since the introduction of dynamic compression plates (DCP) for osteosynthesis, their popularity has increased in the invasive treatment of these fractures. In the latest research, study dynamics have been created regarding concepts such as biological osteosynthesis, minimally invasive osteosynthesis, relative stability and absolute stability [1]. It was Christian Krettec and Harald Tscherne who in 1997 introduced the concept of minimally invasive osteosynthesis. [2]
The concept of biological osteosynthesis refers to the preservation of bone vascularity during surgical intervention to ensure the vitality of the individual fragments and achieve fracture healing with a minimum of damage to the soft tissues and a relative stability that favors the materials. [3]
Conventional osteosynthesis techniques applied for multifragmentary fractures can lead to a variety of complications: delayed union, infections, implant failure and nonunion. This happens because to achieve anatomical reduction, extensive surgical exposure is necessary and, sometimes, the fracture fragments are stripped of the soft tissues that provide vascularity [4-5] The first attempts in the use of biological osteosynthesis They appear in the 80s of the last century; The development of indirect reduction techniques and the use of new osteosynthesis materials caused a basic change in the treatment of fractures.
Every fracture evolves towards consolidation, with pain, inflammation and immobility and reflects what is known as fracture disease, which, if not adequately treated, produces muscle atrophy and generates adhesions that, taken to an extreme, cannot be reversed. and determine sequelae that limit functionality. [6] An adequate quality of life is guaranteed by free and painless movement, this is the philosophy that motivates selecting a fracture fixation technique that allows achieving total mobilization and favors rapid recovery. revascularization of bone and soft tissues.
Minimally invasive osteosynthesis is a method in which the percutaneous use of laminae to remotely fixate the fracture site through minimal exposure is an alternative procedure for the treatment of tibia fractures. [7] We intend to present a series of modifications to the MIPO surgical technique.
A prospective longitudinal study was carried out where the mixed research paradigm was assumed, while quantitative and qualitative data were analyzed in the same study to respond to the research problem.
Theoretical and empirical scientific research techniques were used. With a multi-stage study.
- Stage 1 Explore. Identify and describe the current situation, selection of investigative techniques and the sample for the study.
- Stage 2 Elaborate, where creation, preparation, design of modifications to the MIPO technique are carried out
- Stage 3 Validate the results. Where the evaluation by the group of the modifications is defined.
A semi-structured interview is carried out with specialist doctors linked to trauma care:
After agreement with each professional, a semi-structured interview was carried out in which the level of information and mastery of theoretical and practical aspects associated with traumatology and osteosynthesis was explored.
Semi-structured interview with physicians involved in the care of patients with limb trauma.
General objective: Obtain information about the opinions and assessments of specialist doctors who participate in the process of medical care for patients with trauma of the limbs and spine.
Interviewer-interviewee relationship:
Achieve social interaction, through a process of mutual understanding and trust.
Interview situation:
Carry out in a climate that respects the natural interaction of people characterized by naturalness and free expression.
Guide or guidelines for the development of the interview:
- Exploration of the knowledge that specialist doctors have about the process of medical care for patients with trauma of the limbs and spine.
- Possibilities of proposals for the modification to MIPO osteosynthesis in our context.
- Search for needs and contributions.
Evaluation of the judgment of specialists on the possibility of modifications to the MIPO technique
With the purpose of knowing the opinion of specialists with experience in the subject, regarding osteosynthesis and modifications to the MIPO technique, a questionnaire was applied to evaluate the judgment of specialists.
Description of the sample. The sample was made up of __23__ specialist medical professionals, selected from intentional non-probabilistic sampling. For its selection, the following inclusion criteria were established:
- Willingness and interest to collaborate with the research, expressed through informed consent.
- Theoretical and/or practical knowledge of the topics.
- Possess more than ten years of professional experience.
Focus group: This technique allowed the generation of ideas through the identification of the critical variables of medical care for adult patients with a diagnosis of tibia fracture and the establishment of priorities. An environment was fostered that stimulated interventions to identify the issues. of group consensus. A guide to the topics to be discussed was previously prepared.
Topic guide for Focus Groups.
General objective: Explore the criteria of medical specialists, through individual and group reflection, on the variations in the concepts of osteosynthesis in the new century, the insufficiencies that osteosynthesis with the standard open technique of the fracture focus may present, and the proposals for modifications to the surgical technique.
Selection of participants: ______________________
Selection of the moderator and rapporteur: Moderator: _______________________.
Rapporteur: ___________________________.
Description of the place where it takes place: ______________________________.
Date: _________________.
Hour: _____________.
Steps of the focus group technique:
1. Explanation of the objectives of the technique and the rules of its development.
2. Presentation of the questions.
3. Reflection and individual recording of ideas.
4. Presentation and debate of all ideas.
5. Assessment of common ideas.
At the end of the systematic review on osteosynthesis and surgical treatment with MIPO for tibial diaphyseal fractures, a group technique was carried out with a group of high-category orthopedic professionals, whether scientific, teaching and research, all members of the Cuban Society of Orthopedics and Traumatology, who provided opinions on what modifications to the technique can be made in our current context, with our limitations to offer the population a surgical treatment option that is in accordance with modern principles of osteosynthesis, provides satisfaction and minimizes risks. of the conventional open technique.
Table 1 shows the participation of professionals and the number of interventions and their proposals made.
Proposals
| Participants with proposals for modifications to the MIPO technique | Total participating specialists | |
| Yeah | not | ||
| About instrumental | 14 | 9 | 23 |
| About boarding | 12 | 11 | 23 |
| About tracking | 8 | 13 | 23 |
| About the indications | - | 23 | 23 |
Each of the proposals made was addressed individually and prioritized by the group, who evaluated them to ultimately decide which ones could be proposed for implementation in our service. Table 2.
It can be seen that everyone agrees on the relevance of implementing modifications to the MIPO technique in our context, preparation of professionals for the implementation of the modifications to the technique, the relevance of its implementation, the coherence of the research phases, the rigor scientific of the proposed modifications and compliance with bioethical principles.
# specialist
| Proposals to specialists
| Very suitable
| Suitable | Slightly suitable | Not suitable |
| 23 | Need to design new instruments | 20 | 2 | ||
| 23 | Relevance of implementing modifications to the MIPO technique in our context | 23 | |||
| 23 | Preparation of professionals for the implementation of modifications to the technique | 23 | |||
| 23 | Relevance of its implementation | 23 | |||
| 23 | Coherence of research phases | 23 | |||
| 23 | Quality of the proposed objectives | 22 | 1 | ||
| 23 | Value of the proposed objectives | 19 | 2 | 1 | |
| 23 | Scientific rigor of the proposed modifications | 23 | |||
| 23 | Compliance with bioethical principles | 23 |
Table 2. Prioritization of proposals on the MIPO technique by our specialists
Thanks to the study of a focus group of professionals, a series of proposals are provided to make modifications to the MIPO technique in tibial diaphyseal fractures. These were prioritized by a nominal group of specialists with experience in traumatology for more than 20 years and provided opinion. positive to present them to a group of experts. Based on the impossibility of having a minimally invasive surgery set to perform osteosynthesis in tibia fractures, the same happens with the impossibility of
acquiring minimal contact sheets and with all this providing patients with a treatment option in accordance with the principles modern 2004 osteosynthesis association and combine them with less surgical aggression and the possibility of minimizing risks and avoiding complications.
These professionals led by the project manager presented a series of modifications that, after being prioritized in the group, were as follows, table 3.
| Number | Modifications to the MIPO technique |
| 1 | Use of your own periosteal device, with extra long characteristics. Creation and use of own periosteal system. Figure 1. |
| 2 | Use of AO, narrow DCP sheets, instead of minimum contact sheets. |
| 3 | Creation and use of our own sheet holder, designed by our service team. Figure 2. |
| 4 | Marking of holes by radiological control method and not by templates. |
| 5 | Divergent placement of screws. |
| 6 | At the end of the intervention, use an elastic bandage to cover the surgical area, from the completion of the intervention until two weeks after surgery. |
| 7 | No use of an external tutor before or during surgery |
Table 3. Proposals for modifications to the MIPO technique
Minimally invasive osteosynthesis is a suitable treatment method for tibial fractures and provides a high union rate and a good functional result. It can be an alternative treatment if its indications are taken into account; This technique can be reproducible with AO plates, without the need for special instrumentation (Figure 3) and, as it is a biological osteosynthesis that preserves vascularization and fracture hematoma, it has less risk of complications.
Figure 1. Extra long periosteal. Designed and built in our service.
Figure 2. Own sheet holder, designed by our service team.
Figure 3. Use of the blade holder in tibia fracture surgery.
The modification to the MIPO technique in our context is a necessity since we do not have the specific instruments to perform the technique as described by its authors, however, it complies with the general guidelines of the Arbeitsgemeinschaft für Osteosynthesefragen (AO). This Swiss foundation, created in 1958, defines the principles of osteosynthesis worldwide. The development of AO surgical techniques for the treatment of fractures constituted a major advance in medicine. [8]
The principles of fracture treatment enunciated by the AO are currently reevaluated and redefined. The reformulation of these principles can be interpreted as follows:
Adequate functional reduction: one should always try to achieve the best possible anatomical restoration and the conservation of the longitudinal axis of the bone, a very important factor to allow correct mobilization of the joints neighboring the fracture site.
It is considered a primary or direct bone union in which osteosynthesis is carried out by opposition of the ends, anatomical reduction and interfragmentary compression; Minimally invasive osteosynthesis does not emphasize absolute stability, but rather the preservation of vascularity and soft tissues,[9] this term was developed by the AO/ASIF within the framework of a new conception of bone consolidation in the fractures of the diaphysis and contributes to achieving minimal disturbance of the biology in the fractured area.[10]
The different forms of stability are explained from the histo-morphological point of view the principle of compression is understood, which gave absolute stability, evidenced from the clinical point of view in early, painless movement without the formation of bone callus. to X-rays (consolidation per primam or without callus) -. The biomechanical principle in osteosynthesis is the way in which the implants and the bone in which they are applied function or interact for the surgical treatment of fractures.
At this point, some concepts have changed in recent times:[11] indirect bone union is in which a non-anatomical reduction is achieved, preserving the axis and structural conformation of the bone through a tutor-like system in which a secondary consolidation, with the presence of bone callus and the preservation of the biological environment is prioritized; When a closed or minimally invasive bone reduction is added to this, it is known as biological osteosynthesis. Until very recently this procedure was not considered; the aim was always to faithfully reduce the fragments and place firm materials, by exposing the fracture focus; In light of the updated principles of osteosynthesis, the changes are evaluated.
Stable fixation: it is the most important factor if a satisfactory bone repair is to be achieved because excessive instability of the fragments induces osteolysis, delays the repair and induces a hypertrophic bone callus, even if the repair process fails.
The function of an osteosynthesis material is to achieve relative stability while the fracture site, with its periosteal blood supply, is left virtually untouched. [12] As a consequence, the movement between the fragments causes the fracture to consolidate secondarily with callus formation; Indirect fracture reduction to achieve axial and rotational alignment is a challenging process. The amount of interfragmentary movement is influenced by the stability achieved, which is resolved by the rigidity of the material used, the width of the opening depends on the reduction achieved.
Adequate surgical technique: the surgical technique must be as atraumatic as possible and avoid exaggerated manipulation of the tissues and it is necessary to be very careful with the irrigation of the fragments and the affected bone, all under the best possible conditions. [13] Biology is essential in the preservation of vascularization, with minimal access and minimally invasive osteosynthesis with plates, always guided by images, a precept with which our modifications to the technique comply.
Significant soft tissue injuries contribute to delayed healing, in part due to loss of vascular supply to the bone; The intramedullary vascular supply is normally provided by nutrient vessels that irrigate the medullary contents and part of the cortex. Only the outer third of the cortical bone receives its blood supply from the tissues that cover it (periosteum). The most important factor in the management of the fracture is the care of the soft tissues and maintaining the blood supply to the bone fragments, without damage to the fracture hematoma. [14]
In many displaced fractures of long bones, the spinal vascularization is altered and the vascular supply will depend only on the soft tissues adhered to the periosteum. The involvement of the remaining vascularization by surgical intervention in a displaced fracture has been clearly related to the lack of consolidation, due to the effects of periosteal detachment and soft tissue dissection. As consolidation occurs, the spinal system resumes and a normal vascularization pattern may be reestablished.
- Early mobilization: whenever osteosynthesis allows it, early mobilization of the affected limb should be initiated because it is an important stimulus for osteogenesis; The rapid return to activity significantly reduces the negative effects caused by fracture disease and minimizes muscle atrophy, adhesions and ankylosis.
The author considers that although they are not frequently indicated, these techniques provide the specialist with an alternative method for bone stabilization in complex fractures of the tibia. The final objective, in any case, is to minimize the surgical aggression without reducing the effectiveness of the technique performed because it includes the preservation of the fracture hematoma, less surgical trauma to the soft tissues, the reduction of surgical time and, consequently, the reduction in the risk of infection and, finally, the indirect healing process with abundant callus.
The performance of these techniques must be carried out by specialists experienced in traditional osteosynthesis. We must not forget that, during the learning curve, a mini-invasive procedure may require an open reduction of the focus, so in-depth knowledge of the anatomy of the musculoskeletal system and traditional surgical approaches is essential.
Babst and Khong [15] summarized the indications for minimally invasive osteosynthesis:
- Epi-/metaphyseal fracture
- Inappropriate soft tissue condition
- Intramedullary nailing is not feasible, there is no image intensifier or they are not available.
In fractures of the tibia, these types of implants are indicated in injuries that occur in any area of the bone that ranges from the proximal end, diaphysis and distal end. The indications are the same as for traditional osteosynthesis with open reduction and wide approaches; However, one of the important differences is that minimally invasive plate osteosynthesis does not have as its primary objective anatomical or exact reduction, but only the correct alignment of the fragments in the longitudinal axis. [16] Care should be taken to avoid errors. rotational defects towards medial or lateral and, finally, in multi-fragmented fractures it is important to avoid shortening.
Osteosynthesis planning is essential to determine the length of the implant. It is important to mention that there is no publication, clinical research or textbook that mentions how long the implant should be. Some suggest that the ends of the fracture, proximal and distal, be located and from there measure at least two centimeters to place the screws most proximal to the fracture; It should be taken into account that there must be at least three screws at each end of the implant. [17]
Various reduction methods can be used, from manual to the use of pointed forceps for percutaneous reduction. If the anatomical conditions of the bone and the fracture allow it, it is very important to perform a balanced osteosynthesis; That is, from the center of the fracture towards the ends the same implant distance must be measured. After sliding the plate, radiological control should be performed to ensure that the bone drilling and screw placement are adequate. Finally, the wounds are sutured with conventional technique, without leaving drainage, and the leg is covered with gauze to protect the wounds.
Postoperative management is the same as that used in traditional osteosynthesis. In the case of stable fractures with possibilities of bone support, weight unloading can begin from the beginning with partial weight bearing, which gradually increases until reaching full unloading in a period of six weeks. If there is no bone support (multi-fragmentation), you should wait until you see radiological signs of consolidation before starting weight bearing.
Osteosynthesis evolves theoretically and practically throughout its use, trends in the use of large dissections for more rigid methods of fixation are moving towards minimally invasive osteosynthesis, but universal clinical adoption will depend on the clinical results observed, therefore that the evaluation of works on the subject are necessary to prove its effectiveness. [18-19] These minimally invasive treatments provide adequate union rates, with few complications, as well as fairly good functional results. [20]
Indirect reduction techniques were developed to avoid further soft tissue injury at the fracture site and thus improve fracture healing rates. In relation to the weeks of consolidation, Bingol and collaborators [21] published a study with 30 patients treated using a minimally invasive technique in which a consolidation of 19.2 weeks was obtained, in the study carried out by Zhang [22] the consolidation occurred around of 16.7 weeks and developed by Andalib and collaborators, similar results were obtained and analyzes of the effectiveness of the method were carried out. [23]
Despite the size of the sample in the consulted works and its retrospective design, the results of this research support that the treatment of tibia fracture using the minimally invasive technique has a group of advantages: surgical time is less, with less damage to the soft tissues, the surgical incisions are smaller, less painful and more aesthetic, the hospital stay, blood loss and infection rate are reduced, in general recovery is faster and postoperative pain is reduced.
The largest number of proposals on modifications to the MIPO technique for tibial diaphyseal fractures were made on the instruments, although the proposals are multiple; after prioritizing in the group, seven modifications to the technique remained as proposals. Modifications to the MIPO technique may be another alternative in the therapeutic arsenal, mainly in fracture injuries of the tibia with multiple fragments, although its limitations must be considered if the principles of osteosynthesis are not taken into account. Case studies with a larger number of samples and longer periods of evolution are necessary.
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Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
