AUCTORES
Globalize your Research
Research Article
*Corresponding Author: Waill A. Elkhateeb, Chemistry of Natural and Microbial Products Department, Pharmaceutical Industries Division, National Research Centre, Dokki, Giza, 12622, Egypt.
Citation: Waill A. Elkhateeb and Ghoson M. Daba (2021) Mycotherapy of the good and the tasty medicinal mushrooms Lentinus, Pleurotus and Tremella J. Pharmaceutics and Pharmacology Research. 4(2); DOI: 10.31579/2693-7247/029
Copyright: © 2021, Waill A. Elkhateeb, This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 13 February 2021 | Accepted: 26 February 2021 | Published: 06 March 2021
Keywords: lentinus; pleurotus; tremella; biological activities
Fungi generally and mushrooms secondary metabolites specifically represent future factories and potent biotechnological tools for the production of bioactive natural substances, which could extend the healthy life of humanity. The application of microbial secondary metabolites in general and mushrooms metabolites in particular in various fields of biotechnology has attracted the interests of many researchers. This review focused on Lentinus, Pleurotus, and Tremella as a model of edible mushrooms rich in therapeutic agents that have known medicinal applications.
Mushrooms have been used as a traditional medicine for the last few eras. Mushrooms as higher Basidiomycetes and Ascomycetes contain secondary metabolites in their fruit bodies, cultured mycelium, and cultured broth. Mushrooms have been used in many sides of human activity for many years [1]. Some of these mushrooms have been called medicinal mushrooms due to their various morphological, physiological, and ecological characteristics that are also responsible for their diversity. Medicinal mushrooms produce a wide range of bioactive compounds [1]. Medicinal mushrooms possess medicinal properties such as anti-tumor, immunomodulating, antioxidant, cardiovascular, anti-hypercholesterolemic, anti-viral, anti-bacterial, anti-parasitic, antifungal, detoxification, hepatoprotective, and anti-diabetic effects [2-8]. Hence, mushrooms have gained a lot of attention as a functional food and for the development of drugs and nutraceuticals. [9-12]. Medicinal mushrooms exhibit many biological activities as anti-diabetic potential and Antihyperglycemic agents. The bioactive compound like polysaccharide, protein, lipids, fiber, and some low molecular weight compounds like alkaloids, terpenoids, lactones, lectins, and phenolic substances are involved in many diseases as a therapeutic mediators and also have been shown a major landmark for the cure of diabetes. [13]. The fungi belonging to the genus Ganoderma have been used since ancient times in Eastern traditional medicine in the treatment and prevention of several diseases such as cancer, hypertension, and diabetes, among many other conditions. More than 140 biologically active triterpenoids and 200 polysaccharides, as well as proteins and various metabolites, have been isolated from the fruiting bodies, mycelium and spores of different species of Ganoderma. Species belonging to the genus Ganoderma have been used since ancient times in Eastern traditional medicine, until modern days in the treatment, and prevention of several diseases such as cancer, hypertension, chronic bronchitis, asthma, and others [14, 15]. More recently, different preparations made from mycelium, fruiting bodies, and spores of Ganoderma lucidum have been marketed as dietary supplements due to their antitumor, immunomodulatory, and free radical scavenging abilities [15, 16]. Also, some other species belonging to Ganoderma have various beneficial effects on human health, including Ganoderma tsugae, Ganoderma applanatum, Ganoderma colossum, Ganoderma concinna, Ganoderma pfeifferi, and Ganoderma neo–japonicum [17-19].
The present review focuses on various edible medicinal species of mushrooms belong to genera: Lentinus, Pleurotus,and Tremella, along with their chemical composition, biologically active compounds isolated, and their pharmacological potential.
The most cultivated mushroom worldwide is Agaricus, followed by Lentinus, Pleurotus, and Tremella. Mushrooms production continuously increases, China being the biggest producer around the world [20-22]. However, wild mushrooms are becoming more important for their nutritional, sensory, and especially pharmacological characteristics [23-25]. Lentinus species are normally wood-decaying basidiomycetes and have currently lamellae and domestic tissues in the basidiome, and hyaline, ellipsoid to cylindric spores. Species in the subgenus Lentinus have hyphal pegs. Commonly, the basidiomes are xeromorphic with a tough, firm texture when dry and have a long life is some country like Spain, but in Thailand, their fruits only formatted early in the summer duo to rain season (Figure, 1). Traditionally, Lentinus has been placed in the agaric family Tricholomataceae because species possess a lamellate hymenophore and white spore print [26-28]. Lentinus genus belonging to Class; Agaricomycetes, Order; Polyporales, Family; Polyporaceae. Lentinus species are widespread in tropical Africa, Europe, South America, South East Asia, the Pacific Islands, and Australia [29].
Mushrooms could be an alternative source of new antimicrobial compounds, mainly secondary metabolites, such as terpenes, steroids, anthraquinones, benzoic acid derivatives, and quinolones, but also of some primary metabolites like oxalic acid, peptides, and proteins. Lentinus edodes is the most studied species and seems to have an antimicrobial action against both gram-positive and gram-negative bacteria [30]. Finimundy et al. [31] have provided experimental information about the aqueous extracts of Lentinus edodes as potential sources of antioxidant and anticancer compounds. These extracts significantly decreased cell proliferation on tumors as well.
Species of Lentinus are best known for the commercially important. Lentinus edodes or “shiitake mushroom” has been used for many years to investigate functional properties and to isolate compounds for pharmaceutical use; this is because of its positive effects on human health. It has been utilized to alleviate the common cold for hundreds of years and some scientific evidence has supported this belief [32]. Sevindik, [33], determined that Lentinus tigrinus possessed antioxidant potential, and it was recommended to limit the consumption of this mushroom due to high oxidant values. It was determined that L. tigrinus mushroom collected in regions with adequate oxidative stress levels may be consumed as a natural antioxidant source. Also demonstrated that Lentinus tigrinus has antimicrobial activities against 9 different bacteria and fungi; Staphylococcus aureus, Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa, Acinetobacter baumannii, Candida albicans, Candida krusei, and Candida glabrata.
Lentinus strigellus was cultivated in three different media and the secondary metabolites produced under different culture conditions were isolated and identified by Barros-Filho et al., [34], when cultivated in a liquid medium with peptone, Lentinus strigellus produced benzopyrans, 2,2-dimethyl-6-methoxychroman-4-one, 4-hydroxy-2,2-dimethyl-6-methoxychromane and (3R,4S)-3,4-dihydroxy-2,2-dimethyl-6-methoxychromane. When Lentinus strigellus cultured in Czapek medium enriched with potato broth, the fungus produced the same benzopyrans except (3S,4S)-3,4-dihydroxy-2,2-dimethyl-6-methoxychromane. Panepoxydone and isopanepoxydone were also isolated when Lentinus strigellus was grown in Czapek medium. Extracts and pure compounds of Lentinus edodes exhibit antibacterial, antifungal, cytostatic, antioxidant, anticancer, and immunomodulatory activity. Because of these attributes, different products derived from shiitake are on the market and are sold as dietary supplements [35]. A polysaccharide (LVP) was purified from the fruiting body of Lentinus velutinus by ethanol precipitation fractionation and Sephadex G-100 column chromatography. Udchumpisai and Bangyeekhun, [36], results revealed that the extracted polysaccharide exhibits both cytotoxic and antioxidant activity, and this polysaccharide showed specific cytotoxicity against cancer cells (HeLa and HepG2 cells), and alterations in cancer cell morphology were found after polysaccharide treatment [36]. Catechin is a major group of phenolic compounds found in 3 species of mushroom, Lentinus squarrosulus, Lentinus polychrous, and Lentinus edodes. The percentage of inhibition of free radical scavenging activity by DPPH assay was higher than 70% in ethanolic extract of Lentinus squarrosulus and Lentinus polychrous, while in Lentinus edodes it was lower as 30%. An anticancer protein, polysaccharide peptide (PSP), was also detected [37].
Pleurotus genus, also known as oyster mushrooms, has approximately 40 species and all are commonly edible. In addition to their nutritional value, they possess medicinal properties and other beneficial effects and health-promoting effects. Pleurotus genus belonging to Class; Agaricomycetes, Order; Agaricales, Family; Pleurotaceae. Pleurotus species widespread in Europe and China, Pleurotus mushroom production is responsible for over 70% of the global market. The Pleurotus genus is found naturally in forests grouped to scattered, where they are responsible for the decomposition of wood (Figure, 2). Pleurotus species are valuable to cultivate and eat, as they are the source of valuable nutrients and healing ingredients. Mycelium of white rot is known for its bioremediation abilities, including the accumulation of heavy metals and chlorinated aromatic hydrocarbons. Pleurotus genus has also been found applicable in the biotransformation of unsaturated terpenoid compounds [38, 39]. In Africa, oyster mushrooms are grown mainly on sawdust, with the addition of rice straw [40, 41].
Pleurotus species have been used by humans all over the world for many years [42, 43]. Pleurotus species have been used as medicinal mushrooms for a long time since they contain several compounds with important pharmacological and nutraceutical activities. Some of these substances are lectins with immunomodulatory, antiproliferative, and antitumor activities; phenolic compounds with antioxidant activities; and polysaccharides (polysaccharopeptides and polysaccharide proteins) with immunoenhancing and anticancer activities [44-46].
Exopolysaccharides and internal polysaccharides obtained from the Pleurotus ostreatus M2191 and PBS281009 cultivated using the batch system. The carbohydrate analysis revealed that the polysaccharides comprised 87–89% EPS and 68–74% IPS. The investigation of antioxidant activity in vitro revealed a good antioxidant potential, particularly for Exopolysaccharides and internal polysaccharides isolated from Pleurotus ostreatus [47].
Many researches have indicated that oyster mushrooms contain phenolic compounds with antioxidative effects [48-50]. The fruiting bodies of mushrooms of the Pleurotus genus contain lovastatin, which belongs to the group of statins affecting the metabolism of cholesterol. These compounds inhibit LDL cholesterol oxidation and positively affect the coagulation system and fibrinolysis. They have anti-inflammatory, anticoagulation, and antioxidative properties [51].
Extracts from some Pleurotus species are a good source of prebiotics due to the high soluble fiber content [52]. Research has proved that when an aqueous extract from Pleurotus ostreatus is added to yogurt, it stimulates the growth of useful microorganisms Streptococcus thermophilus and Lactobacillus bulgaricus [53].
The genus Tremella
Tremella is a genus of fungi belonging to Division; Basidiomycota, Class; Termellomycetes, Order; Termellales, Family; Tremellaceae. Basidiocarps (fruit bodies), when produced, are gelatinous and described as the jelly fungi. Tremella species are mainly parasitic on wood-rotting fungi in the two phyla Ascomycota and Basidiomycota, particularly on species that occur on dead attached branches (Figure, 3). Some Tremella species parasitize the fruit bodies of their hosts and sometimes joining host hyphae, and some others parasitize the mycelium within the wood. Tremella species occur worldwide as a group. Over 100 species of Tremella are currently recognized worldwide. Two species, Tremella fuciformis, and Tremella aurantialba are commercially cultivated for food and medicinal activities [54, 55].
Some species belonging to Tremella and their biological activities
Tremella fuciformis, an edible medicinal mushroom, is commonly known as snow fungus, snow ear, silver ear fungus, and white jelly mushroom. Tremella fuciformis belonging to the order of Tremellales and the family of Tremellaceae, which has been traditionally used for health promotion in China and other East Asian countries for many years [56, 57]. Plenty of bioactive substances are discovered in Tremella fuciformis, including fatty acids, proteins, enzymes, polysaccharides, phenols, flavonoids, dietary fiber, and trace elements [58, 59]. Polysaccharides in Tremella fuciformis, widely existed in the fruiting bodies, spores, mycelia and ferment liquor. Tremella fuciformis polysaccharide shows multiple physiological, and healthy promoting effects, such as enhancing immune function, antitumor, anti-oxidation, anti-aging, hypoglycemic, hypolipidemic, neuroprotection, and other effects [60, 61]. Tremella fuciformis polysaccharide has been identified as a major bioactive component. The monosaccharides detected in polysaccharide were mannose, xylose, glucuronic acid, glucose, and galactose. Tremella fuciformis polysaccharides shows multiple physiological and healthy promoting effects including immunomodulation, antitumor, anti-oxidation, anti-aging, hypoglycemic, hypolipidemic, neuroprotection, and other effects [57, 62].
Li, [63], measured the antioxidant activities of various subfractions of the methanol extract of Tremella fuciformis and the major phenolic components of the chloroform subfraction, which showed the highest antioxidant. Tremella fuciformis chloroform subfraction displayed the highest antioxidant activity in all experimental settings and 3 phenolic acids (4-hydroxybenzoic acid, gentisic acid, and 4-coumaric acid) were identified in the chloroform and ethyl acetate subfractions. The chloroform subfraction also exhibited anti-inflammatory activity in LPS-induced RAW 264.7 cells by inhibiting the expression of inducible nitric oxide synthase and thereby suppressing nitric oxide production [64-66].
Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. Auctoresonline publishing platform can be used to facilitate of optimal client-based services and should be added to health care professionals' repertoire of evidence-based health care resources.
Journal of Clinical Cardiology and Cardiovascular Intervention The submission and review process was adequate. However I think that the publication total value should have been enlightened in early fases. Thank you for all.
Journal of Women Health Care and Issues By the present mail, I want to say thank to you and tour colleagues for facilitating my published article. Specially thank you for the peer review process, support from the editorial office. I appreciate positively the quality of your journal.
Journal of Clinical Research and Reports I would be very delighted to submit my testimonial regarding the reviewer board and the editorial office. The reviewer board were accurate and helpful regarding any modifications for my manuscript. And the editorial office were very helpful and supportive in contacting and monitoring with any update and offering help. It was my pleasure to contribute with your promising Journal and I am looking forward for more collaboration.
We would like to thank the Journal of Thoracic Disease and Cardiothoracic Surgery because of the services they provided us for our articles. The peer-review process was done in a very excellent time manner, and the opinions of the reviewers helped us to improve our manuscript further. The editorial office had an outstanding correspondence with us and guided us in many ways. During a hard time of the pandemic that is affecting every one of us tremendously, the editorial office helped us make everything easier for publishing scientific work. Hope for a more scientific relationship with your Journal.
The peer-review process which consisted high quality queries on the paper. I did answer six reviewers’ questions and comments before the paper was accepted. The support from the editorial office is excellent.
Journal of Neuroscience and Neurological Surgery. I had the experience of publishing a research article recently. The whole process was simple from submission to publication. The reviewers made specific and valuable recommendations and corrections that improved the quality of my publication. I strongly recommend this Journal.
Dr. Katarzyna Byczkowska My testimonial covering: "The peer review process is quick and effective. The support from the editorial office is very professional and friendly. Quality of the Clinical Cardiology and Cardiovascular Interventions is scientific and publishes ground-breaking research on cardiology that is useful for other professionals in the field.
Thank you most sincerely, with regard to the support you have given in relation to the reviewing process and the processing of my article entitled "Large Cell Neuroendocrine Carcinoma of The Prostate Gland: A Review and Update" for publication in your esteemed Journal, Journal of Cancer Research and Cellular Therapeutics". The editorial team has been very supportive.
Testimony of Journal of Clinical Otorhinolaryngology: work with your Reviews has been a educational and constructive experience. The editorial office were very helpful and supportive. It was a pleasure to contribute to your Journal.
Dr. Bernard Terkimbi Utoo, I am happy to publish my scientific work in Journal of Women Health Care and Issues (JWHCI). The manuscript submission was seamless and peer review process was top notch. I was amazed that 4 reviewers worked on the manuscript which made it a highly technical, standard and excellent quality paper. I appreciate the format and consideration for the APC as well as the speed of publication. It is my pleasure to continue with this scientific relationship with the esteem JWHCI.
This is an acknowledgment for peer reviewers, editorial board of Journal of Clinical Research and Reports. They show a lot of consideration for us as publishers for our research article “Evaluation of the different factors associated with side effects of COVID-19 vaccination on medical students, Mutah university, Al-Karak, Jordan”, in a very professional and easy way. This journal is one of outstanding medical journal.
Dear Hao Jiang, to Journal of Nutrition and Food Processing We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.
As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.
Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.
International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.
Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.
Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.
I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!
"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".
I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.
We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.
I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.
I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.
I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.
Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.
“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.
Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.
The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.
Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
