info@auctorespublishing.com
+1-(302)-520-2644
+1-(302)-520-2644

Effectiveness of Cognitive Behavioural Therapy on the Single Case Study Obsessive Compulsive Disorder

  1. Home
  2. Journals
  3. Psychology and Mental Health Care
  4. Archives
Submit Guidelines

Research Article

Effectiveness of Cognitive Behavioural Therapy on the Single Case Study Obsessive Compulsive Disorder

  • Noor Shabina 1*
  • Abid Hussain Zaidi 2
  • Sunita Rani 3

*Corresponding Author: Noor Shabina, Clinical Psychologist and Research Scholar In Psychology (Gurukul Kangari University, Haridwar,Uttarakhand)

Citation: Shabina N., Abid H. Zaidi, Rani S. (2022) Effectiveness of Cognitive Behavioural Therapy on the Single Case Study Obsessive Compulsive Disorder.J. Psychology and Mental Health Care, 6(4): DOI: 10.31579/2637-8892/166

Copyright: © 2022, Noor Shabina, This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: 09 March 2022 | Accepted: 13 April 2022 | Published: 07 May 2022

Keywords: obsessive compulsive disorder; anxiety; depression; cognitive behavioral therapy; jacobson’s progressive muscular relaxation

Abstract

This study is a single case therapeutic intervention based report; we have to design pre and post assessment with the help of some psychological rating tools. The present study examined to the effectiveness of cognitive behavioral and some techniques used of same therapeutic relational approaches, this is a pure or predominant obsession is a subtype of obsessive compulsive disorder case according to (ICD-11 under the categories “Obsessive Compulsive Disorder with fair to good Insight, 6B20.0.  Depressive Disorder, GA 34.41. Generalized Anxiety Disorder, 6B00”).  This study used based of cognitive behavior, CBT Model, ERP and used multiple therapeutic techniques of Cognitive behavioral therapy. The present study W, 23 yrs old married male came with chief complaints of the multiple blasphemous thoughts, unwanted sexual images running in the mind, unseen images of sexual area of mother and God since 12 years and seen multiple symptoms of the generalized anxiety or depressive psychopathology. Studying in graduation and belong to middle SES according to kuppuswamy scale. He brought by his parents in IMHH, Agra in OPD and done pre assessment before the applied therapy session. His result showed high severity of OCD symptoms. After 3 months again applied same tools, and seen approximately 50% to 55% major reduction his symptoms that further gradually decreased his symptoms and sessions continued till 2 months. Follow-up continued and patient no longer meet the criteria for OCD, Generalized Anxiety disorders and Depressive symptoms.

Introduction

 OCD is currently considered to be one of the five most prominent psychiatric disorders according to ICD-11. OCD characterized by the presence of obsessions is a multiple types of Obsessive compulsive thoughts which affects approximately1-3% with lifetime prevalence and leading the cause symptoms of other psychiatric illness (Reddy et al., 2017). Cognitive behavior therapy (CBT) involving exposure and response prevention is the high standard for the base of 3rd generation of psychotherapeutic intervention for obsessive-compulsive disorder (OCD).    And twenty-seven patients with Diagnostic and Statistical Manual of Mental Disorders. Fourth Edition diagnosis of OCD. Overall integrated the findings indicating of the 27 patients, 18 (67%) achieved remission (55% reduction in the YBOCS severity score) at 3-month follow-up of the OCD population categories. (Kumar et al., 2016).  Conducted other dimensions of obsessive-compulsive disorder (OCD) is a leading cause of mental or behavioral disorder emergencies with Mind with Body Reaction.   Sexual obsessions are perhaps the least understood manifestation of OCD. Common themes include obsessions about sexual orientation, infidelity, sexual deviations, incest, pregnancy, and blasphemous thoughts combining religion and sex and This book describes new techniques for addressing sexual-OCD (S-OCD) using the cognitive sematic association splitting techniques and helps towards the multiple Obsessive-Compulsive Disturbances. ( APA., 2021).  In this literature showed that the having the difficulty related neurotic disturbances and seen multiple Obsessive-Compulsive symptoms and presented multiple anxiety traits with depressive disorder with solved the case of primary symptoms then secondary multiple other active psychopathology. CBT is the helps of primary symptoms then reduced gradually other symptoms.

Presenting Complaints

  • Headache, disturbance in sleep  Since 12 years
  • Blasphemous thoughts, low mood, low PMA
  • Anxiousness, incresed heart rate, shortness of breathing
  • Seeing images of sexual area of mother and God
  • Violent and aggressive thoughts and images  Since 4 years
  • Checking doors and taps repeatedly
  • Excessive concern with moral fear

Case Summary:

  • Onset was insidious; Course is continuous and Progress is improving

Index patient was functioning well apparently 12 years back when he fell from a height of 8 ft and had a back injury followed which he started complaining of headache. This continued for many years. At about 13 years of age he started engaging in various philosophical thoughts like- “who made Allah, how his face looks like?” Subsequently by 16 years of age, he started masturbating and the act used to often be guilt provoking. Few years later, he started getting involved in a relationship which was unacceptable by family members and since he broke his promise with the girl, he started remaining tensed most times of the day, until one day while sleeping he had thought of having sex with God (Hazrate Fatima). This created a state of intense guilt, anxiety shame and self-blame for which he apologized to God many times. He tried to resist but was unable to do it and started remaining preoccupied with such thoughts. Subsequently, he also started having sexual thoughts for his mother, father and even his own child. In 2010, he got married, after 5 years of marriage he started having images of female vagina. Later, he also started having images of various other sexual organs of female like breast, buttocks etc. However, he remains preoccupied with thought and image of vagina so much that his activities of daily living were hampered such that it become s very difficult to make a decision while sitting or standing as he fears that he will kill Allah or will have sex with his mother if he performs certain acts. Since last 1 year he has also started controlling his thoughts by either replacing image with less threatening image or saying a mental prayer or just avoiding the activities he faces difficulties in performing.

His persistent and pervasive mood has been anxious and irritable. He has difficulty carrying out activates of daily living because of the preoccupation with these thoughts and images. 

Mental Status Examination

On M.S.E. patient was kempt and tidy, in touch with surrounding, eye contact maintained and had a cooperative attitude. His affect was anxious or depressed with normal range and reactivity. In thought possession he reports obsessive thought, increased suicidal wishing and images about sex and aggression as well as checking compulsions. Psychomotor activity was increased during interview time. No abnormality could be elicited in perception with intact judgment and grade IV insight.

Diagnostic Formulation:-

Index Patient X, 23 yrs old unmarried male, studying in graduation, belongs to urban background of Agra. The chief complaints were blasphemous thoughts, Seeing images of sexual area of mother and God, Violent and aggressive thoughts and images, checking doors and taps repeatedly  and excessive concern with moral fears Since 4 years.The significant findings in  MSE indicating obsessions and compulsions, sad mood, insight is grade IV. History and MSE finding suggests that patient is provisionally diagnosed with  ICD-11 “(Obsessive Compulsive Disorder with fair to good Insight,  6B20.0.  Depressive Disorder, GA 34.41. Generalized Anxiety Disorder, 6B00)”.

Psychotherapeutic Formulation:-

He is a member of a joint family, living with his wife, children, parents and brothers. He is a nominal head and his father is a functional head of the family. His family environment is strained because of her obsessive and compulsive behavior. But his primary and secondary support system is good. 

Figure

Pre Assessment for Psychotherapy:- 

  • Yale Brown Obsessive Compulsive Checklist:
  • Aggressive obsessions (Fear of harming others, Violent or horrifying images and Fear of acting on such obsessions);
  • Religious obsessions (Blasphemous thoughts and Excessive concern with morality);
  • Sexual obsessions (Forbidden or unacceptable sexual thoughts and images and Content involving children sometimes),
  • Checking compulsion (checking locks and taps);
  • Mental compulsion (Special prayers) and
  • Past somatic obsessions (Excessive concern with  body parts)

Impression

Raw Score= 31 (Severe Range of Obsessive Compulsive Symptoms)

  • Hamilton Rating Scale For Depression: Raw Score= 16 (Moderate Depression)
  • Beck Depression Inventory(BDI): Raw score= 24 (Major Depression) chiefly in the domains of Pessimism, Past failure, Guilt , Loss of pleasure, Self-dislike and Self-critical
  • Hamilton Rating Scale For Anxiety: Raw Score= 32 (Sever Anxiety) chiefly in the domains of Anxious mood, Tension, Depressed mood and Autonomic symptoms

Model of Therapy:

  • Cognitive Behavior Therapy for Obsessive Compulsive disorder

Goals or the Therapy:

Short term goals :                                                                                                   

  • Psych-education
  • Exposure and response prevention for compulsion
  • Family therapy for strained relationship with her family

Long terms goals:

Cognitive behavior therapy for obsessive thoughts.

  • To modify specific cognitive processes and behaviors that is maintaining the obsessive compulsive symptoms
  • To improve his underlying depressive symptoms
  • To improve his somatic concerns

Techniques Used

Psychoeduaction

Cognitive bio-behavioral self treatment 

Relabel

Re-attribute

  • Behavioral techniques
  • Exposure and response prevention
  • Cognitive techniques

For obsessive ruminations

  • Courtroom play technique
  • Cognitive continuum
  • Thought suppression test
  • Calculating probability estimates

For depressive symptoms 

  • Socratic questioning
  • Down arrow technique
  • Verbal challenging
  • Evidence in favor against of the core beliefs

Duration of sessions: 40-50 minutes, period or total time duration:  6 months to 8 months                          
Number of sessions: 35 to 40 sessions.

  • Target based therapy :
  • Initial Phase

Detailed history was taken from patient. Conversation was carried out to build therapeutic alliance. Detailed psycho-education was given to the patient which included:

  • The session began with discussion on differences between intrusive thoughts that we counter in our day to day life and obsessions
  • Nature and form of obsessions were discussed as repetitive, unwanted thoughts, images, or impulses that a person finds unacceptable and/or repugnant. They are involuntary, harmless, and the opposite of their actual values and desires. People experiencing obsessions recognize that the thoughts are their own production, and find them to be ego-dystonic (contrary to their view of themselves).along with examples of classical obsessional themes usually elicited, example, aggressive, sexual, and blasphemous, including the patient’s obsessional theme as well.
  • Similarly, the nature of compulsions were also introduced as repetitive, intense, stereotypic actions, such as cleaning or checking, that the person carries out in order to remove a perceived threat (e.g. of being contaminated) or to prevent a future threat (e.g. of causing a fire) along with the most common themes elicited as that of contamination, cleaning, symmetry etc. Patient was then asked to define his compulsions.
  • Then the details about the lifetime prevalence of from 2 to 3% equally common among males and females were discussed.
  • The course of the illness as waxing and waning course was explained. In a small minority, perhaps 5%, symptoms will undergo a complete, or near-complete, spontaneous remission; in such cases, however, relapses generally occur in the following years. In another minority of cases, perhaps 10 to 15%, the course is progressively downhill until patients’ lives are consumed by obsessions and compulsions and their responses to them.
  • All the theories explaining the etiology of OCD, along with emphasis on biological, behavioral and cognitive perspectives were explained
  • Then a detailed discussion was also held on the reasons behind the persistence of symptoms and here the case formulation of development and maintenance of OCD was explained to him to develop insight over his own illness.
  • The efficacy of cognitive behavior therapy in the treatment with the rationale given above. Then, the need and rationale for psychotherapy was explained including the details of number of session etc.

MIDDLE PHASE:

Middle phase of the therapy was divided into two phases:

PHASE I: 

In the first phase, the focus was on introducing various cognitive techniques to reduce the self-blame and to initiate a process of challenging over-beliefs and mis-interpretations associated with OCD. This was done in following way:

  • First the patient was asked to Relabel, i.e., label fear-producing cognitive activity, such as intrusive thoughts and images, as obsessions than anything else. For Example: “This thought of stabbing Allah is just an obsession and this urge to pray immediately after that is just a compulsion that my OCD brain thinks will reduce my fear”. Re-labeling was done for various other such beliefs and patient was practiced enough for each of these beliefs. Thereafter, a process of Re-attributing the cause of obsessions and compulsions to the neurobiological condition of OCD rather than calling them a product of the“self” was initiated. For example: “Its not me, it’s just OCD, a neurobiological disorder”. 
  • Then, four domains of cognitive distortions were identified in the patient for which various cognitive techniques were applied.
  • First being sense of Excessive Responsibility for the sexual and blasphemous content. Here, Courtroom play technique was used where therapist acted as judge and patient as prosecuting attorney who presented arguments to prove his guilt for causing a feared consequence. Therapist subsequently challenged these beliefs to reduce the responsibility.
  • The second domain of cognitive distortion is the Over importance of thoughts for which the technique of Cognitive continuum was used. Here patient was asked to assess his moral fears and guilt feelings for having sexual thoughts on a visual analogue scale (0-10) which was compared to a individuals who have committed acts of varying degree of immorality (e.g. serial rapist) to modify his moral thought action fusion.
  • Thirdly, Need to control thoughts was identified as another domain of error where Thought Suppression Test was applied. Patient was instructed to think of a animal as frequently as he can and report it followed by instruction to not to think of an animal and report it. Comparison was made to demonstrate that attempt to suppress distressing obsession thoughts is counter-productive.
  • Lastly, Overestimate of threat or catastrophic misinterpretation was targeted by using Calculating probability estimates Here aatient was asked to provide an estimation of feared consequences (e.g.- having sex with mother). Then he was asked to list a chain of events that will be needed for his feared consequences to occur and the probability of occurrence of each of these events. A comparison was made between gut level estimate and the actual mathematical probability required to perform sex with mother

Phase II: 

Phase II

The next phase of therapy began with a elaborate discussion on the rationale of using ERP (exposure and response prevention) which basically targets the anxiety relieving ability that safety seeking behavior or compulsions produces is very short lived and counter-productive. And as proposed, each of these ERP sessions were followed by various cognitive techniques mentioned in phase I to enhance understanding. For the purpose, Anxiety graph was made and explained to the patient and discussed about rating of subjective unit of distress (SUDS). Then the patient was asked to tell about the anxiety provoking situation & thereafter asked to provide the associated SUDS with each of the situation on 0-100 point visual analogue scale. 

In this phase, brief conversation was carried out about previously discussed matters. Then the patient was exposed to least anxiety provoking situation i.e. putting his hands in the pocket. Before the start of the session therapist did the task to show the patient that it was doable after that patient was made to do it. In this sessions patient was very much distressed & anxious though this task was least anxiety provoking for him. He gave discomfort rating that was started with 35 & then gradually increases to 80 then decreases to 15. The duration of her distress was 1 hour 15 minutes after the exposure he was prevented from engaging in the neutralizing behaviour i.e. compulsive saying of mental prayer. Immediately after the ERP session, revision of various cognitive techniques discussed previously, were introduced again in order to help patient understand the irrationality of thought. This subsequently helps in challenging the dysfunctional assumption and distortion to generate alternative explanations for the problem behavior. The technique of reattribution was again highlighted to make him understand that it the “OCD Brain” thought rather than his personal responsibility. He was asked to practice all these session at home also. Same task was practiced for another sessions. After the 3rd session his distress score was 50. In the 5th session hiss distress score was 25. His distress was decreased within 30 minutes & also prevented from compulsive behavior. In this way patient were exposed to least anxiety provoking situation to the most anxiety situation one by one manner.. Remaining sessions of this phase of treatment will be spent exclusively for ERP. This phase will last for approximately 10 more sessions till he was exposed and subsequently habituated to highest anxiety provoking activities.

Phase III: 

  • Here the main goal is to Increase patient awareness of distorted appraisal of unwanted thoughts through Cognitive restructuring chiefly to target the associated depressive symptoms. Here through Socratic questioning and down-arrow technique, an attempt was made to reach his core beliefs. Hence the process of cognitive restructuring was initiated using the technique of verbal challenging and pros-cons analysis.

Termination Phase:

All previous session were revised. He was able to perform the task well. He was performing all of these with a mild degree of subjective anxiety, & without the following compulsive acts or if performed, within acceptable limits. A health perspective over his illness was also generated which could tackle both his obsessive ruminations and resulting depressive symptoms. Thus, the session was terminated. Patient was then asked to come for booster session.

Result

Post-Therapy Assessment: 

At the end of the final session   all previously used tools were re-administered to monitor progress or client on Y-BOCS, there was a score of 19 indicating moderate range of obsessive compulsive symptoms. On BDI, OARS and HAM-D, there was mild depression indicated by score of 11 and 12 respectively. On OARS, a score of 16 was obtained indicating mild range of anxiety symptoms. The improvement obtained can be graphically depicted like this: 

Table
Figure :2

Anxiety hierarchy was re-plotted to see the difference between the SUDS rating after therapy and the scores obtained are as follows:

Discussion and Conclusion

Index patient’s problem of blasphemous thoughts, Seeing images of sexual area of mother and  God, Violent and aggressive thoughts and images, checking doors and taps repeatedly and excessive concern with moral fears was improved with therapy. Now patient is able manage himself and able to facing any situation.             

The current study understand the OCD, especially sexual obsession towards the own members of the family, this is very stressful situation sometime happened. First of all understand the symptoms and elicited the situation. CBT or JPMR is the best combination of this treatment for the helps of reduced the active psychopathology. Cognitive bio-behavioral self treatment (Schwartz, 1996): Since patient has less knowledge about his illness, he has inflated sense of responsibility and self-blaming towards causing his own illness and hence always remains guilt prone. Thus, these techniques would target at his attribution style which will facilitate better adherence to standard CBT approach. Behavioral technique (ERP): Though ERP has been more standardized for overt compulsive behavior, in the present module patient presents with various covert compulsions. Moreover, Religious patients suffering from blasphemous thoughts often refuse ERP, since they experience such instructions sinful. However, Evidences supporting its efficacy (Abramowitz et al., 2002) proposes that if cognitive techniques immediately follow ERP sessions, especially with mental compulsions, behavior therapy can lead to successful outcome (Gordon 2005; et al., 1992). Cognitive Therapy: It has been suggested as standard treatment approach for altering both strongly held beliefs associated with OCD symptoms and interpretations of intrusive mental experiences change responsibility beliefs and appraisals and thereby to reduce distress and eliminate neutralizing responses, which usually occurred as covert neutralizing (mental) rituals (Rachman & Hodgson, 1980; Salkovskis, 1998).

Future Plan:

Urgent care:

  • Contact your doctor if your symptoms worsen or don't respond to treatment. OCD typically has periods when symptoms become worse no apparent reason. Seek help at such times to adjust your medication or for help in modifying your behavior. 
  • If your symptoms don't respond to treatment, you may need to be hospitalized. Many psychiatric facilities provide varying levels of care, such as day care, evening care, and residential programs.
  • Self Care:
  • You and your organization should learn as much as possible about OCD. OCD sufferers may wish to join the Obsessive-Compulsive Foundation or a local support group if available.
  • Symptoms can sometimes be brought under control with medications or behavioral therapy. Even with appropriate treatment, most people with the disorder experience symptoms that wax and wane throughout life

References

  1. American Psychiatric Association. (2013). Diagnostic and Statistical Manual of Mental Disorders (5th Ed.). Washington, DC: Author.
    View at Publisher | View at Google Scholar
  2. Bürkle, J. J., Fendel, J. C., & Schmidt, S. (2021). Protocol: Mindfulness-based and acceptance-based programmes in the treatment of obsessive–compulsive disorder: a study protocol for a systematic review and meta-analysis. BMJ Open, 11(6).
    View at Publisher | View at Google Scholar
  3. Halvorsen, M., Samuels, J., Wang, Y., Greenberg, B. D., Fyer, A. J., McCracken, J. T., ... & Goldstein, D. B. (2021). Exome sequencing in obsessive–compulsive disorder reveals a burden of rare damaging coding variants. Nature Neuroscience, 24(8), 1071-1076.
    View at Publisher | View at Google Scholar
  4. Kogan, C. S., Stein, D. J., Rebello, T. J., Keeley, J. W., Chan, K. J., Fineberg, N. A., ... & Reed, G. M. (2020). Accuracy of diagnostic judgments using ICD-11 vs. ICD-10 diagnostic guidelines for obsessive-compulsive and related disorders. Journal of affective disorders, 273, 328-340.
    View at Publisher | View at Google Scholar
  5. Kumar, A., Sharma, M. P., Narayanaswamy, J. C., Kandavel, T., & Reddy, Y. J. (2016). Efficacy of mindfulness-integrated cognitive behavior therapy in patients with predominant obsessions. Indian journal of psychiatry, 58(4), 366.
    View at Publisher | View at Google Scholar
  6. Laforest, M., Bouchard, S., Bossé, J., & Mesly, O. (2016). Effectiveness of in virtuo exposure and response prevention treatment using cognitive–behavioral therapy for obsessive–compulsive disorder: A study based on a single-case study protocol. Frontiers in psychiatry, 7, 99
    View at Publisher | View at Google Scholar
  7. Panda, T. K. (2021). Effectiveness of Mindfulness Integrated Cognitive Therapy in Children and Adolescents with Obsessive Compulsive Disorder: a Preliminary Study.
    View at Publisher | View at Google Scholar
  8. Rentala, S., & Ng, S. M. (2021). Application of Mobile Call-Based Integrative Body–Mind–Spirit (IBMS) Intervention to Deal With Psychological Issues of COVID-19 Patients: A Case Study in India. Journal of Holistic Nursing, 0898010121993001.
    View at Publisher | View at Google Scholar
  9. Reddy, Y. J., Sundar, A. S., Narayanaswamy, J. C., & Math, S. B. (2017). Clinical practice guidelines for obsessive-compulsive disorder. Indian journal of psychiatry, 59(Suppl 1), S74.
    View at Publisher | View at Google Scholar
  10. Simpson, H. B., Foa, E. B., Liebowitz, M. R., Ledley, D. R., Huppert, J. D., Cahill, S., ... & Petkova, E. (2008). A randomized, controlled trial of cognitive-behavioral therapy for augmenting pharmacotherapy in obsessive-compulsive disorder. American Journal of Psychiatry, 165(5), 621-630.
    View at Publisher | View at Google Scholar
  11. Samson, F., Tafuto, B., Jose, N., & Kim, L. P. K. (2021). Technology-based CBT in Reducing Symptoms of OCD in Children: A Systematic Review. J Pub Health Issue Pract, 5(1), 177.
    View at Publisher | View at Google Scholar
  12. World Health Organization . The“newly defined” burden of mental problems. Fact Sheets n°217. Geneva: WHO, 1999.
    View at Publisher | View at Google Scholar
  13. Williams, M. T., & Wetterneck, C. T. (2019). Sexual obsessions in obsessive-compulsive disorder: A step-by-step, definitive guide to understanding, diagnosis, and treatment. Oxford University Press.
    View at Publisher | View at Google Scholar
  14. Yousaf, A., Kausar, R., & Fatima, I. (2020). Cognitive behaviour therapy with compulsive hoarding: a single case study. Journal of the Pakistan Medical Association, 1-10.
    View at Publisher | View at Google Scholar

Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. Auctoresonline publishing platform can be used to facilitate of optimal client-based services and should be added to health care professionals' repertoire of evidence-based health care resources.

img

Virginia E. Koenig

Journal of Clinical Cardiology and Cardiovascular Intervention The submission and review process was adequate. However I think that the publication total value should have been enlightened in early fases. Thank you for all.

img

Delcio G Silva Junior

Journal of Women Health Care and Issues By the present mail, I want to say thank to you and tour colleagues for facilitating my published article. Specially thank you for the peer review process, support from the editorial office. I appreciate positively the quality of your journal.

img

Ziemlé Clément Méda

Journal of Clinical Research and Reports I would be very delighted to submit my testimonial regarding the reviewer board and the editorial office. The reviewer board were accurate and helpful regarding any modifications for my manuscript. And the editorial office were very helpful and supportive in contacting and monitoring with any update and offering help. It was my pleasure to contribute with your promising Journal and I am looking forward for more collaboration.

img

Mina Sherif Soliman Georgy

We would like to thank the Journal of Thoracic Disease and Cardiothoracic Surgery because of the services they provided us for our articles. The peer-review process was done in a very excellent time manner, and the opinions of the reviewers helped us to improve our manuscript further. The editorial office had an outstanding correspondence with us and guided us in many ways. During a hard time of the pandemic that is affecting every one of us tremendously, the editorial office helped us make everything easier for publishing scientific work. Hope for a more scientific relationship with your Journal.

img

Layla Shojaie

The peer-review process which consisted high quality queries on the paper. I did answer six reviewers’ questions and comments before the paper was accepted. The support from the editorial office is excellent.

img

Sing-yung Wu

Journal of Neuroscience and Neurological Surgery. I had the experience of publishing a research article recently. The whole process was simple from submission to publication. The reviewers made specific and valuable recommendations and corrections that improved the quality of my publication. I strongly recommend this Journal.

img

Orlando Villarreal

Dr. Katarzyna Byczkowska My testimonial covering: "The peer review process is quick and effective. The support from the editorial office is very professional and friendly. Quality of the Clinical Cardiology and Cardiovascular Interventions is scientific and publishes ground-breaking research on cardiology that is useful for other professionals in the field.

img

Katarzyna Byczkowska

Thank you most sincerely, with regard to the support you have given in relation to the reviewing process and the processing of my article entitled "Large Cell Neuroendocrine Carcinoma of The Prostate Gland: A Review and Update" for publication in your esteemed Journal, Journal of Cancer Research and Cellular Therapeutics". The editorial team has been very supportive.

img

Anthony Kodzo-Grey Venyo

Testimony of Journal of Clinical Otorhinolaryngology: work with your Reviews has been a educational and constructive experience. The editorial office were very helpful and supportive. It was a pleasure to contribute to your Journal.

img

Pedro Marques Gomes

Dr. Bernard Terkimbi Utoo, I am happy to publish my scientific work in Journal of Women Health Care and Issues (JWHCI). The manuscript submission was seamless and peer review process was top notch. I was amazed that 4 reviewers worked on the manuscript which made it a highly technical, standard and excellent quality paper. I appreciate the format and consideration for the APC as well as the speed of publication. It is my pleasure to continue with this scientific relationship with the esteem JWHCI.

img

Bernard Terkimbi Utoo

This is an acknowledgment for peer reviewers, editorial board of Journal of Clinical Research and Reports. They show a lot of consideration for us as publishers for our research article “Evaluation of the different factors associated with side effects of COVID-19 vaccination on medical students, Mutah university, Al-Karak, Jordan”, in a very professional and easy way. This journal is one of outstanding medical journal.

img

Prof Sherif W Mansour

Dear Hao Jiang, to Journal of Nutrition and Food Processing We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.

img

Hao Jiang

As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.

img

Dr Shiming Tang

Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.

img

Raed Mualem

International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.

img

Andreas Filippaios

Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.

img

Dr Suramya Dhamija

Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.

img

Bruno Chauffert

I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!

img

Baheci Selen

"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".

img

Jesus Simal-Gandara

I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.

img

Douglas Miyazaki

We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.

img

Dr Griffith

I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.

img

Dr Tong Ming Liu

I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.

img

Husain Taha Radhi

I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.

img

S Munshi

Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.

img

Tania Munoz

“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.

img

George Varvatsoulias

Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.

img

Rui Tao

Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.

img

Khurram Arshad

Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.

img

Gomez Barriga Maria Dolores

The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.

img

Lin Shaw Chin

Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.

img

Maria Dolores Gomez Barriga

Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.

img

Dr Maria Dolores Gomez Barriga

Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.

img

Dr Maria Regina Penchyna Nieto

Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.

img

Dr Marcelo Flavio Gomes Jardim Filho

Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”

img

Zsuzsanna Bene

Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner

img

Dr Susan Weiner