AUCTORES
Globalize your Research
Case Report
*Corresponding Author: Rayo-Pérez Ana María, Bachelor's Degree in Podiatry from the University of Seville. Official Master's Degree in Foot Surgery from the Catholic University of Murcia. Honorary Research Assistant in the Department of Podiatry at the University of Seville. Ad
Citation: Rayo-Pérez Ana María, Rodríguez-Castillo Francisco Javier, Raquel Garcia de la Peña, (2024), Calcaneal bone edema. A case of series, J Clinical Research and Reports, 16(5); DOI:10.31579/2690-1919/408
Copyright: © 2024, Rayo-Pérez Ana María. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 12 September 2024 | Accepted: 18 September 2024 | Published: 16 October 2024
Keywords: bone edema; calcaneus; heel pain; chronic pain; plantar fascitis; neuropathy
bone edema or bone edema is an uncommon pathology in podiatric practice. However, there are some cases we can detect within it. This bone alteration results from trauma, degenerative lesions, or metabolic processes, with the first being the most common cause. It is characterized by acute pain in the heel area, which gradually becomes more generalized, as well as redness and swelling of the area. In the initial stages, the use of NSAIDs or analgesics is recommended, and in more advanced stages, drainage of the area. This study is aa prospective observational study analyzing 20 subjects with calcaneal bone edema. Various surveys such as AOFAS, SF-36, and VAS are conducted to fully analyze the condition and its evolution after 3 months and 6 months post-treatment. Following the intervention, there is a notable improvement in the patients' quality of life, as well as a significant reduction in pain. In conclusions calcaneal bone edema is an underdiagnosed pathology mainly due to its lack of recognition and low prevalence. It is essential to know the differential diagnosis with other heel pains to comprehensively address this condition.
Heel pain, known as talalgia, affects 14% of the population at some point in their lives. It is a common clinical condition that typically resolves spontaneously within 10 to 12 months from the onset. However, in the remaining 10% of cases, it progresses into a chronic pain syndrome, characterized by a complex array of conditions such as recalcitrant fasciopathy, Baxter's nerve neuropathy, tarsal tunnel syndrome, calcaneal bone edema, or pain secondary to biomechanical compensations. [1–3]
Throughout history, this condition has been increasingly well-defined, beginning with Baxter in 1984, who described a complex clinical picture involving recalcitrant plantar fasciitis and Baxter's nerve neuropathy. This was further supported by Bordelon in 1984 and Jorgensen in 1985, who reported similar clinical cases. In the early 21st century, Labib expanded on this by describing a condition comprising plantar fasciitis, tarsal tunnel syndrome, and posterior tibial dysfunction, a finding that was later supported by Odgen's study in 2004. The most recent reference in the literature comes from 2010, when Silvestre Muñoz added calcaneal congestive syndrome to the established conditions of plantar fasciitis and Baxter's neuropathy. [4–7]
The literature on this syndrome highlights several common risk factors in affected individuals, including a sedentary lifestyle, female gender, limited ankle dorsiflexion, excessive pronation of the subtalar joint, and low vitamin D levels. These factors contribute to microfractures in the trabeculae of the calcaneus, leading to the development of the syndrome. [8–10]
Focusing on calcaneal bone edema, or calcaneal congestive syndrome, there is a significant lack of literature on this specific condition as it pertains to the foot. This gap in knowledge leads to a general lack of awareness among healthcare professionals, resulting in underdiagnosis and, consequently, the chronicity of the condition. [7,9]
Calcaneal bone edema can be defined as an increase in fluid with lymphocytic infiltration within the Ward's triangle of the calcaneus, causing disabling pain that predominantly occurs at night. Diagnosis is primarily clinical, typically confirmed with the squeeze test, though fluoroscopy or MRI can be used for corroboration. Its etiology remains unknown, but it is associated with a degenerative bone process, leading to a stress fracture in one of the calcaneal trabeculae, which in turn causes the edema. [2,5,8,11]
The conservative treatment approach, as reported in the literature, involves physical therapy through magnetotherapy or shockwave therapy, as well as vitamin D supplements. However, these treatments are often not curative, necessitating the consideration of invasive methods. The earliest references date back to 1974 when Hassab suggested making 7 to 10 perforations in the lateral cortex of the calcaneus. Subsequent authors, such as Santinini et al. and Seewoonarain et al., advocated for drilling with a 1.8 mm K-wire, either through the lateral or plantar aspect of the calcaneus to avoid damaging any vital structures. In 2020, Rayo et al. proposed performing one or two perforations in the lateral aspect of the calcaneus, followed by aspiration of the clot. [2,8,12–14]
The objective of this article is to determine the pain and quality of life of patients with calcaneal bone edema at 3 and 6 months post-intervention.
Methodology
Data collection for this study was conducted from January 2021 to March 2023. However, due to the low prevalence of the condition, the data collection period was extended until December 2023 to obtain significant data.
An observational, prospective, non-randomized study was conducted with the following criteria [12-14]:
• Inclusion Criteria: Subjects with chronic heel pain lasting more than one year, subjects with previous therapeutic failures, and subjects without a definitive diagnosis.
• Exclusion Criteria: Minors, pregnant women or those with a probability of being pregnant, and subjects with systemic diseases that precluded participation in the study.
A pre-screening was conducted to select subjects based on their suitability for the study. A total of 20 subjects were selected. Once the necessary documentation for participation was provided and the basic medical history was completed, each subject completed the following scales [12-14]:
• Visual Analog Scale (VAS): For pain assessment.
• SF-36 Scale: For quality of life assessment.
• AOFAS Scale: For assessing lower limb function.
These scales were administered at the first consultation and during follow-up visits at 3 and 6 months after the last treatment.
To evaluate the pathology, subjects were asked to undergo a magnetic resonance imaging (MRI) scan of the foot in both coronal and sagittal views to fully visualize the calcaneus in both its longitudinal and transverse axes. Additionally, fluoroscopy was performed to determine the location of the edema, identified by the presence of the double cortical sign [14] (Illustration 1).
Fluoroscopy of Calcaneal Bone Edema. Source: Own elaboration.
Once a definitive diagnosis of bone edema was confirmed, a clot drainage procedure was performed under local anesthesia on an outpatient basis. This procedure involved making a perforation in the lateral cortex of the calcaneus, precisely in the area corresponding to the edema. After the perforation, a 14G needle was used to aspirate the serohematic contents of the edema (Illustration 2)
Drainage. Source: Own elaboration.
After the procedure, the patient was advised to rest for at least 48 hours and was prescribed oral analgesia (Paracetamol 1g every 8 hours).
After collecting the data for this study, a statistical analysis was performed using Jamovi® version 2.3.26. The results include data related to the general characteristics of the subjects, general biopsychosocial data, examination data, specific data concerning calcaneal bone edema, and specific data on concomitant pathologies.
The data indicate that of the 20 subjects analyzed, 85% were female and 15% were male. These figures are consistent with the typical patient
demographics observed in our clinic, where approximately 75% of patients are women. The average age of the subjects was 57.7 years (SD 9.537). The average height was 1.664 meters (SD 0.072), and the average weight was 77.6 kilograms (SD 11.704).
Regarding the duration of the condition, the average time of progression was 4.95 years (SD 2.139), highlighting the chronic nature of the condition. Notably, 20% of the subjects had a condition lasting either 4 or 6 years.
When analyzing pain (Table 1), the trend showed a significant reduction in pain following treatment, with the average pain score decreasing from 9.1 points before treatment to 0.19 points at 6 months after the final clinical intervention.
| Time Point | Pre-Treatment | 3 Months Post-Treatment | 6 Months Post-Treatment |
| Mean (VAS Score) | 9.1 | 0.95 | 0.19 |
| Sample Standard Deviation | 0.912 | 1.356 | 0.512 |
Table 1: Pain Evolution According to the Visual Analog Scale (VAS). Source: Own data.
| Time Point | Pre-Treatment | 3 Months Post-Treatment | 6 Months Post-Treatment |
| Mean (AOFAS Score) | 20.25 | 60.65 | 89.7 |
| Sample Standard Deviation | 7.893 | 12.857 | 9.895 |
Table 2: Evolution of AOFAS. Source: Own data.
| Time Point | Pre-Treatment | 3 Months Post-Treatment | 6 Months Post-Treatment |
| Mean (SF-36 Score) | 25.1 | 62.35 | 94.35 |
| Sample Standard Deviation | 6.95 | 13.152 | 6.515 |
Table 3: Evolution of SF-36. Source: Own data.
In all subjects of the sample, various tests are conducted to diagnose calcaneal bone edema. In 100% of the cases, the diagnosis is clinical, based on the Squeeze Test, and is accompanied in 35% of cases by fluoroscopy, followed by 30% of cases involving magnetic resonance imaging in coronal and sagittal planes.
Regarding drainage, an average extraction of 9.75 milliliters (SD 5.848) is achieved, with 80
In the year 2000, Dienst M et al. [15] published a clinical case where a patient, after experiencing an axial overload contusion, was diagnosed with bone hematoma in both calcanei via magnetic resonance imaging and bone scintigraphy, following the absence of pathological findings in radiographs and the persistence of the individual's symptoms. This article was the first to reference this clinical entity in the scientific literature and its treatment. Unlike our case series, the treatment was conservative, relying on partial unloading of the left foot (the right foot's symptoms resolved) for approximately 4 months.
Later, in 2003, Santinini S et al. [13] published a study involving 21 patients (25 feet) with chronic heel pain unresponsive to conservative treatment. Although these authors did not refer to the clinical entity of calcaneal bone edema, they noted that patients underwent intervention due to increased uptake on bone scintigraphy. In this instance, as with our patients, surgical treatment was employed, though it involved three microperforations via a medial approach. We, however, used a lateral approach to the lesion out of respect for vascular and nervous structures.
In 2010, Zhou S et al. [16] conducted a study on 50 cadaveric calcanei to analyze the internal microarchitecture of this bone and its relation to fractures occurring within it. Results showed different groups of bone lamellae and, consequently, two potentially weak areas, allowing for the prediction of potential fracture lines. This article shares the zones of bone hypodensity described in our study where calcaneal bone edema is located.
That same year, Thorning C et al. [10] carried out another investigation involving 70 magnetic resonance imaging scans of patients with diabetes and foot ulceration. They concluded that bone marrow edema in the mid and posterior parts of the foot is common in individuals with this pathological condition, although it is usually transient and idiopathic. None of our patients had this condition, but it could be considered an influencing factor in the occurrence of calcaneal bone edema in addition to biomechanical factors.
In 2016, Singh S et al. [9] published a study on the conservative treatment of 18 bone edemas located in the foot, treated with immobilization using a pneumatic boot, either with or without bisphosphonate administration. Good results were obtained at two years of follow-up regarding symptom reduction, though it is noteworthy that only 11% of patients had bone edema in the calcaneus.
In 2018, Hörterer H et al. [17] analyzed the complexity of treating bone edema in the foot and ankle and proposed the possibility of therapy with a prostacyclin analogue, in this case, iloprost, administered intravenously. These authors assessed short- and medium-term results and, although they achieved a 60% reduction in pain and an 80% reduction in bone edema within three months of treatment, they reported minor complications in 12 patients, along with unresolved pain and significant deterioration on magnetic resonance imaging after two years of follow-up.
A year later, Booz C et al. [11] studied virtual reconstruction without calcium via computed tomography compared to magnetic resonance imaging for traumatic calcaneal bone edema. Different radiologists, blinded to the results, analyzed data and images from 62 patients with traumatic calcaneal bone edema, concluding that both quantitative and qualitative analyses of this complementary test showed excellent diagnostic accuracy. This could open a diagnostic pathway for this condition, alongside bone scintigraphy with contrast and magnetic resonance imaging, as demonstrated in our study.
In 2022, Qingwen et al. [18] published an article analyzing calcaneal fractures and their relationship with the internal bone structure. They retrospectively analyzed a total of 226 calcaneal fractures in 210 patients, creating a 3D model from six views of the bone. The study concluded that fracture maps can be created showing recurring patterns of this bone's involvement based on the distribution of its trabecular bone. These maps align, as observed in the previous image, with the most commonly vulnerable areas of the bone described in our study.
In the same year, Chirvi S et al. [19] evaluated the relationship between calcaneal bone density and fractures in 14 cadaveric specimens, concluding that there are significant differences between the bone density of the anterior and posterior regions of the calcaneus. This could help infer the location of fractures in a bone subjected to significant loads. Similarly, our study also shows differences in the intrinsic bone density that predisposes to the location of bone edema in our case.
It is evident that in the scientific literature of the past 20 years, there are few articles published on the diagnosis and management of calcaneal bone edema. Many diagnostic methods and therapies, primarily conservative, are described, leading to controversy in addressing this condition. In our case series, we propose an effective method that significantly reduces symptoms in the short term, allows for a rapid return to normal life for the patient, and respects noble structures (vessels and nerves) by using a lateral surgical approach to the lesion.
There are few studies on calcaneal bone edema, as well as on the quality of life of these patients and its association with other pathologies. This leads to a widespread lack of understanding of the condition, resulting in its underdiagnosis. Therefore, there is a need for a greater number of clinical studies to create high-quality literature on this topic.
The authors declare no conflict of interest.
None.
Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. Auctoresonline publishing platform can be used to facilitate of optimal client-based services and should be added to health care professionals' repertoire of evidence-based health care resources.
Journal of Clinical Cardiology and Cardiovascular Intervention The submission and review process was adequate. However I think that the publication total value should have been enlightened in early fases. Thank you for all.
Journal of Women Health Care and Issues By the present mail, I want to say thank to you and tour colleagues for facilitating my published article. Specially thank you for the peer review process, support from the editorial office. I appreciate positively the quality of your journal.
Journal of Clinical Research and Reports I would be very delighted to submit my testimonial regarding the reviewer board and the editorial office. The reviewer board were accurate and helpful regarding any modifications for my manuscript. And the editorial office were very helpful and supportive in contacting and monitoring with any update and offering help. It was my pleasure to contribute with your promising Journal and I am looking forward for more collaboration.
We would like to thank the Journal of Thoracic Disease and Cardiothoracic Surgery because of the services they provided us for our articles. The peer-review process was done in a very excellent time manner, and the opinions of the reviewers helped us to improve our manuscript further. The editorial office had an outstanding correspondence with us and guided us in many ways. During a hard time of the pandemic that is affecting every one of us tremendously, the editorial office helped us make everything easier for publishing scientific work. Hope for a more scientific relationship with your Journal.
The peer-review process which consisted high quality queries on the paper. I did answer six reviewers’ questions and comments before the paper was accepted. The support from the editorial office is excellent.
Journal of Neuroscience and Neurological Surgery. I had the experience of publishing a research article recently. The whole process was simple from submission to publication. The reviewers made specific and valuable recommendations and corrections that improved the quality of my publication. I strongly recommend this Journal.
Dr. Katarzyna Byczkowska My testimonial covering: "The peer review process is quick and effective. The support from the editorial office is very professional and friendly. Quality of the Clinical Cardiology and Cardiovascular Interventions is scientific and publishes ground-breaking research on cardiology that is useful for other professionals in the field.
Thank you most sincerely, with regard to the support you have given in relation to the reviewing process and the processing of my article entitled "Large Cell Neuroendocrine Carcinoma of The Prostate Gland: A Review and Update" for publication in your esteemed Journal, Journal of Cancer Research and Cellular Therapeutics". The editorial team has been very supportive.
Testimony of Journal of Clinical Otorhinolaryngology: work with your Reviews has been a educational and constructive experience. The editorial office were very helpful and supportive. It was a pleasure to contribute to your Journal.
Dr. Bernard Terkimbi Utoo, I am happy to publish my scientific work in Journal of Women Health Care and Issues (JWHCI). The manuscript submission was seamless and peer review process was top notch. I was amazed that 4 reviewers worked on the manuscript which made it a highly technical, standard and excellent quality paper. I appreciate the format and consideration for the APC as well as the speed of publication. It is my pleasure to continue with this scientific relationship with the esteem JWHCI.
This is an acknowledgment for peer reviewers, editorial board of Journal of Clinical Research and Reports. They show a lot of consideration for us as publishers for our research article “Evaluation of the different factors associated with side effects of COVID-19 vaccination on medical students, Mutah university, Al-Karak, Jordan”, in a very professional and easy way. This journal is one of outstanding medical journal.
Dear Hao Jiang, to Journal of Nutrition and Food Processing We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.
As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.
Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.
International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.
Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.
Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.
I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!
"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".
I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.
We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.
I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.
I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.
I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.
Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.
“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.
Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.
The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.
Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
