AUCTORES
Research Article
*Corresponding Author: Abdulwahab Ismail Al-Kholani, Professor of Restorative Dentistry, Dental Implant Consultant, Restorative and Esthetic Dentistry Department, Faculty of Dentistry, Sana’a University, Sana’a, Yemen.
Citation: Ali Al-kinani MA, Al-Shameri BHH, Mohsen Ali Al-Hamzi, Al-kholani AI, Amaal M. Alnesairy, et al, (2024), Root and Canal Morphology of Permanent Maxillary and Mandibular Canines in a Sample of Yemeni Population Using Cone Beam Computed Tomography, J Clinical Research and Reports, 16(5); DOI:10.31579/2690-1919/412
Copyright: © 2024, Abdulwahab Ismail Al-Kholani. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 18 September 2024 | Accepted: 30 September 2024 | Published: 07 October 2024
Keywords: cone-beam computed tomography; maxillary canine; mandibular canine; root morphology; yemeni population
Aims and Objective: This study aimed to investigate the external and internal morphological characteristics, including crown shape, root curvature, canal diameter, and root canal configuration, of maxillary and mandibular canine teeth in a Yemeni population using cone-beam computedtomography (CBCT).
Materials and Methods: A total of 400 CBCT images (200 maxillary, 200 mandibular) were analyzed from 400 Yemeni subjects (averageage 34).
Results: All maxillary canineshad a single root, while 4% of mandibular canineshad two roots (slightly higherin females, but not significantly). Maxillary canines were markedly larger in males (p = 0.001). Most maxillary canines(98.5%) had a single root canal, while 16.5% of mandibular canines had two (significantly higher in males). Using the Vertucci classification, root canal configuration analysis showed that maxillary canineswere predominantly Type I, while mandibular canines displayed more variation.
Conclusion: This study provides insights into the morphological characteristics of Yemeni canine teeth. Gender is a significant factor in canine dimensions, with males having larger teeth.
Successful endodontic treatments require a comprehensive understanding of root canal system (RCS) morphology. Lack of familiarity with anatomical variations can lead to incomplete cleaning, shaping, and filling, resulting in treatment failure. [1]
Canine teeth play a crucial role in dental occlusion, mastication, and esthetics. Understanding their external and internal morphology is ess ential for various clinical procedures, including root canal treatment, tooth extraction, and prosthetic rehabilitation. Anatomical variations in the number of roots and root canal morphology can significantly impact the complexity and success of endodontic and surgical interventions. [4, 5]
Previous studies have investigated the external and internal morphology of canine teeth in different populations using various imaging techniques. These studies have reported variations in the number of roots, root canal configurations, and anatomical dimensions across different ethnic and geographic groups. [6, 7]
Cone-beam computed tomography (CBCT) has become an invaluable tool in dental research and clinical practice. It provides high-resolution three-dimensional (3D) images, allowing for detailed analysis of tooth morphology. [8, 9]
To the best of our knowledge, no studies have investigated the external and internal morphological characteristics of maxillary and mandibular canine teeth in a Yemeni population using CBCT imaging. This study aimed to analyze the morphology, including the number and type of roots, as well as the anatomical dimensions of maxillary and mandibular canine teeth in a sample of the Yemeni population using CBCT.
Study Design and Sample Selection
This cross-sectional study utilized CBCT images of Yemeni subjects. A total of 400 CBCT images were analyzed, with 200 each for maxillary and mandibular canines. The study population consisted of 400 Yemeni individuals aged 18-50, with an equal distribution of males and females for each jaw.
Inclusion criteria:
• Yemeni individuals aged 18-50 years
• Complete set of permanent dentition
• No previous dental treatments or abnormalities in canine teeth
• High-quality CBCT images without artifacts or distortions
Exclusion criteria:
• Pathological conditions or developmental anomalies in canine teeth
• Poor image quality or significant artifacts in CBCT images
The study was approved by the Institutional Review Board, and informed consent was obtained from all participants.
CBCT Image Acquisition and Analysis
All CBCT images were acquired using a standardized protocol with a Planmeca ProMax 3D Mid machine. Scans were performed with an 8x8 cm field of view, a 0.2 mm voxel size, and a 12-second exposure time.
Two experienced oral and maxillofacial radiologists analyzed the CBCT images using Planmeca Romexis software. The number and type of roots, as well as the anatomical dimensions (crown length, root length, and total length) of the maxillary and mandibular canine teeth, were assessed and recorded.
Statistical Analysis
Data were analyzed using SPSS software. Descriptive statistics, including frequencies, percentages, means, and standard deviations, were calculated. The Chi-square test was used to compare the number of roots between genders, and the independent t-test was used to compare anatomical dimensions between male and female subjects. A p-value of less than 0.05 was considered statistically significant.
Root Anatomy of Maxillary and Mandibular Canines
Root Number:
• Maxillary canines: All maxillary canines examined had a single root.
• Mandibular canines: 96% were single rooted, while 4% had two roots. There was a slightly higher incidence of two-rooted mandibular canines in females compared to males, but this difference was not statistically significant (p > 0.05). (Table 1)
Anatomical Dimensions:
• Maxillary canines:
The average anatomical length of the maxillary canine crown was 8.3 mm, and the root was 16.8 mm.
The total average length was 25.1 mm.
Male patients had significantly longer maxillary canines than female patients (p = 0.001). (Table 2)
Mandibular canines:
Single-rooted mandibular canines had an average root length of 15.5 mm, crown length of 7.8 mm, and total length of 23.3 mm. (Table 3)
oTwo-rooted mandibular canines had an average root length of 12.5 mm per root, crown length of 9.4 mm, and total length of 21.9 mm. (Table 3)
Male individuals had significantly larger mandibular canines than female individuals (p = 0.001). (Table 4)
Root Canals:
• Maxillary canines: 98.5% had a single root canal, while 1.5% had two. There was no significant difference between males and females. (Table 5)
• Mandibular canines: 83.5% had a single root canal, while 16.5% had two. Males had a significantly higher prevalence of two-canal mandibular canines compared to females (p = 0.04). (Table 5)
Root Canal Configurations:
• Maxillary canines: The most common configuration was Type I (98.5%), followed by Type III (1%) and Type VII (0.5%). No significant differences were observed between males and females. (Table 6)
• Mandibular canines: The most common configuration was Type I (83.5%), followed by Type III (11%). Significant differences were found between genders, with Type I and Type V being more prevalent in females and Type III being more common in males. (Table 6)
Bilateral Symmetry:
• Maxillary canines: There was 100% bilateral symmetry for the number of roots, 99% for the number of root canals, and 99% for canal configurations. (Table 7)
• Mandibular canines: There was 98% bilateral symmetry for the number of roots, 97% for the number of root canals, and 95% for canal configurations. (Table 7)
Overall, maxillary canines consistently exhibited a single root and a single root canal, while mandibular canines showed more variation in root and canal anatomy.
Root canal | Male (100) | Female (100) | Total | CI 95% | ||||
N | % | N | % | N | % | Max | Man | |
One root | 97 | 48.5% | 95 | 47.5% | 192 | 96.0% | 2.5 | 0.1 |
Two roots | 3 | 1.5% | 5 | 2.5% | 8 | 4.0% | ||
OR | 0.6 | |||||||
*χ2 = 0.5 p= 0.5 |
Table 1. Number of roots in the mandibular canines.
Gender | Root length | Crown length | Total length | |||
N | Mean ±SD | N | Mean ±SD | N | Mean ±SD | |
Male | 100 | 17.7±1.8 | 100 | 8.4±1.0 | 200 | 26.2±1.9 |
Female | 100 | 15.8±2.1 | 100 | 8.1±0.7 | 200 | 23.9±2.2 |
(male+ female) | 200 | 16.8 | 200 | 8.3 | 200 | 25.1 |
P Value | 0.001 | 0.006 | 0.001 |
Table 2: The cumulative mean tooth length of maxillary canine (root & crown)of the female and male.
variable | Average length | Root | Crown | Total (root+ crown) |
One root | N=192 | 15.5 | 7.8 | 23.3 |
Two roots | N=8 | L+B=12.5 | 9.4 | 21.9 |
Table 3: The average lengthof mandibular canines with one and two roots
Variable | Male | Female | P | ||
N | Mean ±SD | N | Mean ±SD | ||
Root length | 97 | 16.2±1.6 | 95 | 14.8±2.2 | 0.001 |
Root length (L)* | 3 | 11.8±2.3 | 5 | 13.3±0.4 | 0.4 |
Root length (B)* | 3 | 11.8±2.3 | 5 | 13.2±0.4 | 0.4 |
Crown length | 100 | 7.9±0.9 | 100 | 7.7±0.9 | 0.1 |
Total length | 97 | 24.0±1.9 | 95 | 22.5±2.5 | 0.001 |
Total lengthof teeth has two roots | 3 | 21.6±2.5 | 5 | 22.5±0.7 | 0.6 |
*L: lingual root / *B: buccal root
Table 4. The cumulative mean tooth lengthof the mandibular canine (root& crown) of the femaleand male.
Variable | Root canal | Male (100) | Female (100) | Total (200) | CI 95% | P value | ||||
N | % | N | % | N | % | Max | Man | 0.6 | ||
Maxillary canines | One canal | 98 | 49.0% | 99 | 49.5% | 197 | 98.5% | 22.6 | 0.2 | |
Two canals | 2 | 1.0% | 1 | 0.5% | 3 | 1.5% | ||||
Mandibular canines | One canal | 78 | 39.0% | 89 | 44.5% | 167 | 83.5% | 5.0 | 1.04 | 0.04 |
Two canals | 22 | 11.0% | 11 | 5.5% | 33 | 16.5% |
Table 5. Distribution of number of canals in permanent maxillary and mandibular canines
Variable | Gender | Type I | Type II | Type III | Type V | Type VII | P value | |||||
N | % | N | % | N | % | N | % | N | % | 0.6 | ||
Maxillary canines | Male (100) | 98 | 49.0% | … | … | 1 | 0.5% | … | … | 1 | 0.5% | |
Female (100) | 99 | 49.5% | … | … | 1 | 0.5% | … | … | 0 | 0.0% | ||
Total | 197 | 98.5% | … | … | 2 | 1.0% | … | … | 1 | 0.5% | ||
Mandibular canines | Male (100) | 78 | 39% | 2 | 1.0% | 17 | 8.5% | 3 | 1.5% | … | … | 0.04 |
Female (100) | 89 | 44.5% | 1 | 0.5% | 5 | 2.5% | 5 | 2.5% | … | … | ||
Total | 167 | 83.5% | 3 | 1.5% | 22 | 11.0% | 8 | 4% | … | … |
Table 6. Distribution of root canal configuration in permanent maxillary and mandibular canines.
Variable | Maxillary canines | Mandibular canines | ||||
Right (n=100) | Left (n=100) | Number of symmetrical teeth | Right (n=100) | Left (n=100) | Number of symmetrical teeth | |
One root | 100 | 100 | 200 | 97 | 95 | 190 |
Two roots | ----------- | ----------- | ------ | 3 | 5 | 6 |
Total | 100 | 100 | 200 | 100 | 100 | 196 |
Total symmetry n (%) | 100% | 98% | ||||
One root canal | 98 | 99 | 196 | 85 | 82 | 164 |
Two root canals | 2 | 1 | 2 | 15 | 18 | 30 |
Total | 100 | 100 | 198 | 100 | 100 | 194 |
Total symmetry n (%) | 99% | 97% | ||||
Vertucci type I | 98 | 99 | 196 | 85 | 82 | 164 |
Vertucci type II | … | … | … | 1 | 2 | 2 |
Vertucci typeIII | 1 | 1` | 2 | 9 | 12 | 18 |
Vertucci type V | …….. | ……… | ……. | 3 | 5 | 6 |
Vertucci typeVII | 1 | ………. | 0 | … | … | … |
Total | 100 | 100 | 198 | 100 | 100 | 190 |
Total symmetry n (%) | 99% | 95% |
Table 7. Bilateral symmetryof maxillary and mandibular canines.
A comprehensive understanding of root canal morphology is paramount for the successful outcome of endodontic treatment. However, dentists must be vigilant in identifying less common root canal variations to ensure proper treatment. The failure to locate and treat all root canals can lead to negative treatment outcomes [10].
Since the late 19th century, various techniques have been employed to study dental root canal anatomy, including replication [11], histopathological analysis [12], radiography [13], microscopy [14], and micro-computed tomography (micro-CT) [15]. While these methods have provided valuable insights, they often involve invasive procedures that can alter the true morphology.
To overcome the limitations of previous techniques, cone-beam computed tomography (CBCT) has emerged as a non-invasive, three-dimensional imaging modality for evaluating external and internal dental anatomy. CBCT offers accurate, isotropic imaging that allows for precise visualization and measurement of anatomical features, unlike traditional medical CT scans [16]. The increasing use of CBCT in clinical practice has facilitated a better understanding of normal and atypical root canal morphology, which is crucial for improving the success of endodontic treatments [17].
The primary objective of this study was to investigate the morphology and canal anatomy of the roots of maxillary and mandibular permanent canines in a sample of the Yemeni population using an in vivo CBCT method.
This study found a 4% incidence of double roots in lower canines, which is consistent with the 4.7% rate reported in an Iranian population [18]. However, this rate is higher than those reported in several other populations, such as Iraqi (2.17%), Saudi (0.2%, 2.88%, and 1.6%), Moscow (0.2%), Turkish (3.1% and 3.4%), Brazilian (1.7%), Chinese (0.7%), South Asian Indian (0%), Chongqing (0.8%), Malaysian (1.21%), Iranian (1.3% and 1.6%), and Syrian (2.15%) [19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 7, 31]. In contrast, the rate is lower than the 12.08% reported in the Iranian population [32] and the 5.2% reported in the Pakistani population [33], as well as the 5.8% found in a Serbian population [34]. The variations in the incidence of double roots in lower canines across different populations could be attributed to genetic, racial, and geographical factors.
Regarding the maxillary canines, the present study did not find any instances of two-rooted maxillary canines, which is consistent with several previous studies conducted in various populations worldwide, including the USA by Green, UK, Mexico, Brazil, Vertucci in the USA, South Africa, Moscow, Turkey, and Iran [36, 37, 38, 13, 39, 23, 25, 22].
The present study found that gender had no significant effect on the distribution of root numbers in the maxillary and mandibular canines among the Yemeni population. This finding is consistent with studies conducted on Saudi Arabian populations [40, 20, 21]. Similar results were also reported in a Malaysian subpopulation [30]. In contrast, studies on Iranian and Turkish populations have reported statistically significant differences in the number of roots between gender [7, 25]. The variations in gender-based differences across different populations suggest that root canal morphology of canines may be influenced by genetic, racial, and geographical factors.
The prevalence of two canals in mandibular canines in this study was found to be 16.5%, which is higher than the values reported in several previous studies. Pineda and Kuttler [13] found a prevalence of 13.5%, Pecora et al. [26] reported 7.8%, Han et al. [41] found 6.3%, Kayaoğlu et al. [24] reported 6.1%, Mağat found 9.4% [42], Okumus and Kanyılmaz reported 7.2% [43], Büyükbayram et al. found 15.8% [44], Soleymani et al. found 11.6% [7], Almohaimede et al. reported 9.94% [21], and Mashyakhy found 9.3% [40]. However, the prevalence found in the present study was lower than that reported by Rahimi et al. (20.48%) [33], Vertucci (22%) [39], Aminsobhani et al. (28.2%) [18], Sert et al. (24%) [12], Naseri (18.4%) [31], and Amardeep et al. (20.4%) [45].
Regarding the maxillary canines, the present study found that 98.5% had a single canal, and only 1.5% had two canals. These findings are consistent with the results reported by Mashyakhy in a Saudi population (99% with one canal, 1% with two canals) [40] and Almohaimede et al. in a Saudi population (98.1% had one canal, 1.9% had two canals) [21]. However, these results differ from those in Malaysian and Iranian populations, where 100% of the maxillary canines had a single canal [30, 46]. The study by Naseri et al. in an Iranian population reported a higher frequency of two root canals in maxillary canines (34.9%), which is significantly different from the present findings [31]. This variation could be attributed to ethnic and genetic differences.
In this study, the prevalence of two canals in both maxillary and mandibular canine teeth was higher in males than females. This finding is consistent with the observations made by Sert and Bayirli [12], Altunsoy et al. [6], and Soleymani et al. [7], who also reported a higher incidence of two-canal canines in male subjects. In contrast, Kayaoğlu et al. [24] reported that canines with two canals were more often found in females than in males. This discrepancy in findings across different studies may be attributed to variations in study populations, sample sizes, and the diagnostic techniques employed. The average anatomical length of the maxillary canine crown was 8.3 mm in this study, which is not consistent with previous reports, which have stated the average maxillary canine crown length to be 10 mm [47] and 9.61 mm [45]. The average root length of the maxillary canine in the current study was 16.8 mm, which is in closer agreement with the previously reported averages of 17 mm [47] and 16.82 mm [45]. The total average length of the maxillary canine (crown and root) in the present study was 25.1 mm, which is shorter than the international average records of 26.5 mm [48] and 27.31 mm [49]. This discrepancy may be attributed to potential population-specific variations in tooth dimensions.
Regarding the mandibular canine, the average crown length in the present study was 7.8 mm, which is shorter than the 11 mm reported by Ash and Nelson [47]. The average root length of the mandibular canine was 15.5 mm, and the root was significantly longer in males than in females. These findings are consistent with the studies by Versiani et al. [50], Amardeep et al. [45], Soleymani et al. [7], and Doumani et al. [32], who also observed gender-related differences in mandibular canine root lengths.
The present study also revealed that the average tooth length of the evaluated maxillary and mandibular canines among Yemeni males was significantly longer than that in females. This observation is in line with the findings reported by Kulkarni et al. [51]. Based on Vertucci's classification, 83.5% of the mandibular canines were found to have a Type I canal configuration, followed by Type III (11%), Type V (4%), and Type II (1.5%). Our results agree with those reported in a previous investigation in a Saudi subpopulation by Mashyakhy [40] and Almohaimede et al. [21], in a Turkish population [25], and in an Iranian population [31], where most canal configurations were Type I followed by Type III and Type V. However, another study in a Saudi subpopulation by Al Dahman et al. [20] and Vertucci's study [39] found that the second most commonly occurring canal pattern was Type II followed by Type III. In another study in a Saudi population [22], it was recorded that Type I canal configuration was found in most mandibular canines (95.8%), followed by Type III (1.9%) and Type II (1.1%). Type IV canal pattern in mandibular canines was not observed in this study, whereas several studies showed this configuration pattern in lower canines [39, 13, 12, 26].
This study, conducted through CBCT imaging of a Yemeni population, offers significant insights into the external and internal morphological characteristics of maxillary and mandibular canine teeth. Our findings reveal that gender plays a substantial role in determining the anatomical dimensions of both maxillary and mandibular canines, with males exhibiting larger canine dimensions than females. Regarding root canal anatomy, the maxillary canine was predominantly found to have a single root canal, with a low prevalence of two-canal configurations. In contrast, the mandibular canine exhibited a higher occurrence of two-canal configurations, especially in male individuals.
An analysis based on Vertucci's classification revealed that the majority of maxillary canines had a Type I root canal configuration, with no significant gender-related differences. However, the distribution of root canal types in mandibular canines differed significantly between males and females. These results hold important clinical implications for various dental procedures and contribute to a deeper understanding of dental anatomy within the Yemeni population.
This study provides valuable insights into the external and internal morphological characteristics of maxillary and mandibular canine teeth in a Yemeni population using CBCT imaging. The findings suggest that gender is an influential factor in the anatomical dimensions of both maxillary and mandibular canine teeth, with male subjects exhibiting larger canine dimensions compared to their female counterparts The theory of maxillary canines had a single root canal, with a low prevalence of two-canal anatomy. In contrast, the mandibular canines exhibited a higher occurrence of two-canal configurations, particularly in male individuals.
The analysis of root canal configurations based on Vertucci's classification revealed that the majority of maxillary canines had a Type I configuration, with no significant gender-related differences. However, the distribution of root canal types in mandibular
Limitations:
• Sample size: A larger sample is needed for broader generalizability.
• Age range: Expanding the age range can explore age-related variations.
• Other factors: Systemic diseases, medications, and dental trauma should be considered.
• CBCT limitations: Image resolution can be inadequate for small or calcified canals.
• Comparative studies: Compare with other populations for global variations.
• Developmental aspects: Investigate root canal development over time.
• Correlation with dental problems: Explore the relationship between morphology and dental issues.
• Advanced imaging: Use micro-CT for higher-resolution images.
• Clinical implications: Study the impact of morphology on endodontic treatment outcomes.
The authors declare that they received no funding for this research.
The authors declare that they have no conflicts of interest.
• Manar Abdulsalam Ali Al-kinani: Primary investigator, data analysis, manuscript writing
• Other authors: Data collection, analysis, interpretation, manuscript review
• Supervisor: Professor Abdulwahab Al-kholani study conception, guidance, oversight, manuscript review
Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. Auctoresonline publishing platform can be used to facilitate of optimal client-based services and should be added to health care professionals' repertoire of evidence-based health care resources.
Journal of Clinical Cardiology and Cardiovascular Intervention The submission and review process was adequate. However I think that the publication total value should have been enlightened in early fases. Thank you for all.
Journal of Women Health Care and Issues By the present mail, I want to say thank to you and tour colleagues for facilitating my published article. Specially thank you for the peer review process, support from the editorial office. I appreciate positively the quality of your journal.
Journal of Clinical Research and Reports I would be very delighted to submit my testimonial regarding the reviewer board and the editorial office. The reviewer board were accurate and helpful regarding any modifications for my manuscript. And the editorial office were very helpful and supportive in contacting and monitoring with any update and offering help. It was my pleasure to contribute with your promising Journal and I am looking forward for more collaboration.
We would like to thank the Journal of Thoracic Disease and Cardiothoracic Surgery because of the services they provided us for our articles. The peer-review process was done in a very excellent time manner, and the opinions of the reviewers helped us to improve our manuscript further. The editorial office had an outstanding correspondence with us and guided us in many ways. During a hard time of the pandemic that is affecting every one of us tremendously, the editorial office helped us make everything easier for publishing scientific work. Hope for a more scientific relationship with your Journal.
The peer-review process which consisted high quality queries on the paper. I did answer six reviewers’ questions and comments before the paper was accepted. The support from the editorial office is excellent.
Journal of Neuroscience and Neurological Surgery. I had the experience of publishing a research article recently. The whole process was simple from submission to publication. The reviewers made specific and valuable recommendations and corrections that improved the quality of my publication. I strongly recommend this Journal.
Dr. Katarzyna Byczkowska My testimonial covering: "The peer review process is quick and effective. The support from the editorial office is very professional and friendly. Quality of the Clinical Cardiology and Cardiovascular Interventions is scientific and publishes ground-breaking research on cardiology that is useful for other professionals in the field.
Thank you most sincerely, with regard to the support you have given in relation to the reviewing process and the processing of my article entitled "Large Cell Neuroendocrine Carcinoma of The Prostate Gland: A Review and Update" for publication in your esteemed Journal, Journal of Cancer Research and Cellular Therapeutics". The editorial team has been very supportive.
Testimony of Journal of Clinical Otorhinolaryngology: work with your Reviews has been a educational and constructive experience. The editorial office were very helpful and supportive. It was a pleasure to contribute to your Journal.
Dr. Bernard Terkimbi Utoo, I am happy to publish my scientific work in Journal of Women Health Care and Issues (JWHCI). The manuscript submission was seamless and peer review process was top notch. I was amazed that 4 reviewers worked on the manuscript which made it a highly technical, standard and excellent quality paper. I appreciate the format and consideration for the APC as well as the speed of publication. It is my pleasure to continue with this scientific relationship with the esteem JWHCI.
This is an acknowledgment for peer reviewers, editorial board of Journal of Clinical Research and Reports. They show a lot of consideration for us as publishers for our research article “Evaluation of the different factors associated with side effects of COVID-19 vaccination on medical students, Mutah university, Al-Karak, Jordan”, in a very professional and easy way. This journal is one of outstanding medical journal.
Dear Hao Jiang, to Journal of Nutrition and Food Processing We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.
As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.
Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.
International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.
Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.
Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.
I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!
"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".
I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.
We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.
I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.
I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.
I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.
Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.
“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.
Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.
The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.
Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner