Evaluation of Failure Factors of Fixed Prosthesis in a Sample of Yemeni Dental Patients - Sana'a City

Research Article

Evaluation of Failure Factors of Fixed Prosthesis in a Sample of Yemeni Dental Patients - Sana'a City

  • Mohsen Ali Al-Hamzi1 1
  • Samah Nabil Al-Hammadi2 2
  • Abdulwahab Ismail Al-Kholani 3*
  • Ibrahim Zaid Al-Shami 4

*Corresponding Author: Abdulwahab Ismail Al-kholani,Dean of Faculty of Dentistry on 21 September University, Yemen, Head of Restorative and Esthetic Dentistry, Dental Implant Consultant.

Citation: Mohsen Ali Al-Hamzi, Samah Nabil Al-Hammadi, Abdulwahab Ismail Al-kholani, Ibrahim Zaid Al-Shami, (2024), Evaluation of Failure Factors of Fixed Prosthesis in a Sample of Yemeni Dental Patients - Sana'a City, J Clinical Research and Reports, 16(5); DOI:10.31579/2690-1919/410

Copyright: © 2024, Abdulwahab Ismail Al-Kholani. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: 18 September 2024 | Accepted: 27 September 2024 | Published: 08 October 2024

Keywords: fpds; fixed partial denture failures; crown and bridge failures

Abstract

Tooth loss is a prevalent global health issue. The World Health Organization (WHO) estimates that nearly 7% of individuals aged 20 or older have complete tooth loss, increasing to 23% for those aged 60 or older. Fixed partial dentures (FPDs) are a common restorative option but often face failure.

Aim: This study investigated factors contributing to FPD failure in Yemeni patients.

Methods: A cross-sectional study was conducted on 208 FPD failure cases from 117 patients. Clinical examination, periodontal probing, and radiographic assessment were performed. Data on biological, mechanical, and aesthetic failures were collected.

Results: Biological factors accounted for 75% of failures, followed by aesthetic (18%) and mechanical (7%). The primary biological contributors were poor oral hygiene, periodontal problems, and food impaction. The most common mechanical failures were prosthesis fractures and dislodgements. Shade mismatch was the primary aesthetic issue.

Conclusion: FPD failures in Yemeni patients were primarily attributed to biological factors, emphasizing the importance of oral hygiene and periodontal health maintenance. Addressing these factors is crucial for the long-term success of FPDs

Introduction

Teeth serve vital functions in daily life, including chewing, communication, and facial aesthetics. Tooth loss, a common global issue, primarily stems from untreated caries and periodontal disease, but can also result from trauma or congenital absence. To address this, fixed partial dentures (FPDs) are frequently used to replace missing teeth.

FPDs can significantly improve a patient's quality of life by restoring function and aesthetics. However, their success depends on various factors, including patient care, clinician expertise, and prosthesis quality. Biological, mechanical, and aesthetic complications can lead to FPD failure, impacting patient satisfaction and overall oral health.

While FPDs offer a promising solution for tooth loss, understanding the factors that contribute to their failure is essential for optimizing treatment outcomes and ensuring long-term patient well-being. This study aimed to investigate the prevalence and types of FPD failures in a Yemeni population.

Materials and Methods

Study Design

This cross-sectional clinical study was conducted between June 2020 and August 2022 at the Departments of Conservative Dentistry in the Faculty of Dentistry, Sana'a University and the University of Science and Technology, Sana'a, Yemen.

Study Site and Population

Participants were recruited from patients attending the polyclinics of the Faculty of Dentistry and the University of Science and Technology. All subjects were adults, regardless of gender.

Sample Size Calculation

A sample size of 208 fixed partial dentures (FPDs) was calculated using the following formula:

n = (z^2 * p̂ * (1 - p̂)) / ε^2

Where:

• n is the desired sample size

• z is the number of standard deviations (1.44 for an 85% confidence level)

• p̂ is the estimated proportion of the outcome in the target population (set at 50% for a maximum estimate of FPD prevalence in the Yemeni population)

• ε is the maximum size of the standard error (set at 5%)

Sampling Method

Randomized sampling was employed to select Yemeni dental patients attending the Faculty of Dentistry, Sana'a University, and the University of Science and Technology.

Inclusion Criteria

• Subjects must be adults aged 18-50 years.

• Subjects must have crowns or bridges.

Exclusion Criteria

• Medically compromised conditions.

• Complete edentulous patients.

• Pregnant women.

• Individuals over 50 years old.

Study Methods

Patient Selection: Patients who met the inclusion criteria and did not have any exclusion criteria were included in the study.

Data Collection:

• Case Sheet: A standardized case sheet was used to collect patient information, including medical and dental history, intraoral examination findings, and information about the fixed prosthesis.

• Examination Instruments: Mirror, tweezer, explorer, periodontal probe, and dental x-rays (periapical or panoramic) were used for clinical examination.

• Data Collection Procedure: Patients attending dental clinics were examined clinically for fixed prostheses. A detailed case sheet was completed for patients with issues related to their crowns or FPDs.

• Failure Factors: Biological, mechanical, and aesthetic factors were assessed. Biological factors included periapical lesions, gingivitis, periodontitis, secondary caries, mobility, poor oral hygiene, bone resorption, and abscess formation. Mechanical factors included dislodged prosthesis, fracture of an abutment, prosthesis fracture, traumatic occlusal force, and loss of restoration along with abutment teeth. Aesthetic factors included shade mismatch and contour discrepancies.

Statistical Analysis: Descriptive statistics, including mean, standard deviation, and percentages, were used to analyze the collected data.

Note: The specific examination methods for each failure factor have been provided in Table 1.

Table 1: The Examination Methods of Fixed Prosthesis Failure Factors

CauseExamination Method
Periapical lesionPeriapical x-ray
GingivitisBleeding on probing
PeriodontitisPocket depth
Secondary cariesProbing on the margin of restoration
MobilityDegree of Horizontal mobility
Poor oral hygieneBrushing and plaque accumulation
Bone resorptionPeriapical x-ray
Pain and swellingPatient history
Abscess formationBy vision and patient history
Shade mismatch and Contour discrepanciesBy vision
Fracture of an abutmentPeriapical x-ray
Prosthesis fractureBy vision

Results

A total of 208 fixed partial dentures (FPDs) were analyzed from 117 participants (89 females and 28 males, mean age: 35.76 ± 8.06 years). Participants' demographic characteristics and academic levels are summarized in (Tables 2&3&4)

Table 2: Demographic information of the study participants

Table 3: The mean age of the study participants

Table 4: The academic level of the study participants

Academic LevelFemale (n = 89)Male (n = 28)Total (n = 117)
Illiterate44246
Primary47855
Middle13316
High19928
College392463

FPD Characteristics

Age: 56% of FPDs were at least five years old, followed by 30% aged two to four years, and 14% less than one year.

Material: All the studied FPDs were PFM. It has been not found that FPDs made of all ceramic, all metal, or any other materials.

Position: 106 FPDs were in the upper arch, while 102 were in the lower arch.

Location: 70% of FPDs were posterior, 16% anteroposterior, and 14% anterior.

Units: 30% of FPDs had one unit, 30% had three, 22% had two, and 18% had at least four units.

Material used
 

Material of ProsthesisNo. of cases (n = 208)Percentage %
PFM208100%
All ceramic00%
All metal00%
Others00%

Table 5: Material of Prosthesis

As seen in Table 5, all of the fixed partial dentures (FPDs) analyzed in the study were made of porcelain-fused-to-metal (PFM). No other materials, such as all ceramic or all metal, were found in the sample. This indicates that PFM is the predominant material used for FPDs in the Yemeni population studied.

The Relationship Between Failure Factors and Various Variables

The study examined the relationship between FPD failure and several factors, including age, academic level, brushing frequency, prosthesis age, position, location, and number of units. The findings are summarized in Tables 6-13.

This table provides an overview of the most common failure factors, with poor oral hygiene, periodontal problems, shade mismatch, and food impaction being the primary contributors. 

Failure FactorsPercentage %
Poor oral hygiene19%
Periodontal problem (gingivitis/periodontitis)17%
Shade mismatch15%
Food impaction13.3%
Secondary caries12.7%
Pain6%
Periapical lesion5%
Prosthesis fracture4%
Contour discrepancies3%
Dislodged prosthesis2%
Mobility1%
Abscess formation1%
Fracture of an abutment0.6%
Swelling0.4%
Loss of restoration along with abutment teeth0%

Table 6: Prevalence of Failure Factors

Prevalence of Failure Factors in Descending Order

• Younger patients (≤34 years old): More likely to experience mechanical failures like dislodged prosthesis and prosthesis fracture.

• Older patients (>34 years old): More likely to experience biological failures like periodontal problems, food impaction, and poor oral hygiene.

Type of FailureFailure Factors≤ 34 years old> 34 years old
Biological failurePeriodontal problem (gingivitis/periodontitis)53 (28%)82 (20%)
 Food impaction28 (15%)76 (19%)
 Poor oral hygiene44 (24%)100 (24%)
 Mobility0 (0%)8 (2%)
 Periapical lesion13 (7%)28 (7%)
 Secondary caries27 (14%)76 (19%)
 Bone resorption0 (0%)3 (0.9%)
 Pain16 (9%)31 (7%)
 Swelling0 (0%)1 (0.2%)
 Abscess formation5 (3%)3 (0.9%)
Mechanical failureDislodged prosthesis11 (55%)6 (19%)
 Fracture of an abutment1 (5%)2 (7%)
 Prosthesis fracture8 (40%)23 (74%)
 Loss of restoration along with abutment teeth0 (0%)0 (0%)
Esthetic failureShade mismatch38 (83%)80 (82%)
 Contour discrepancies8 (17%)18 (18%)
Total 32%68%

Failure Factors Concerning Age

Table 7: Failure Factors Concerning Age

• Lower education levels (illiterate, primary): Higher rates of periodontal problems, food impaction, and poor oral hygiene.

• Higher education levels (college): Higher rates of shade mismatch and contour discrepancies.

Failure FactorsIlliteratePrimaryMiddleHighCollege
Periodontal problem29 (15%)32 (13.5%)12 (23%)22 (21%)39 (20%)
Food impaction28 (14%)31 (13%)7 (14%)11 (11%)29 (14.5%)
Poor oral hygiene38 (20%)46 (19%)12 (23%)17 (16%)28 (14%)
Mobility5 (2%)3 (1%)0 (0%)0 (0%)0 (0%)
Periapical lesion12 (6%)11 (5%)1 (2%)2 (2%)15 (7%)
Secondary caries25 (13%)32 (13.5%)8 (15%)16 (16%)22 (11%)
Bone resorption0 (0%)2 (1%)0 (0%)1 (1%)1 (0.5%)
Pain9 (5%)19 (8%)2 (4%)5 (5%)11 (5%)
Swelling1 (1%)0 (0%)0 (0%)0 (0%)0 (0%)
Abscess formation3 (2%)2 (1%)0 (0%)0 (0%)3 (1.5%)
Dislodged prosthesis5 (2%)2 (1%)0 (0%)2 (2%)8 (4%)
Fracture of an abutment0 (0%)1 (0.5%)0 (0%)0 (0%)2 (1%)
Prosthesis fracture5 (2%)15 (6.5%)1 (2%)6 (6%)5 (2.5%)
Shade mismatch29 (15%)30 (13%)8 (15%)15 (15%)35 (17%)
Contour discrepancies6 (3%)10 (4%)1 (2%)5 (5%)4 (2%)
Total195 (25%)236 (30%)52 (6.5%)102 (13%)202 (25.5%)

Table 8: Failure Factors Concerning Academic Level

Failure Factors Concerning Academic Level

•               Lack of brushing: Significantly higher rates of all failure factors.

•               Consistent brushing: Lower rates of failure factors.

Failure FactorsOnceTwiceThree timesNo brushing
Periodontal problem41 (16%)7 (24%)0 (%)85 (16%)
Food impaction34 (13%)4 (13%)0 (%)65 (12%)
Poor oral hygiene34 (13%)2 (7%)0 (%)111 (20.5%)
Mobility3 (1%)0 (0%)0 (%)5 (1%)
Periapical lesion13 (5%)2 (7%)0 (%)27 (5%)
Secondary caries25 (9.5%)1 (3%)0 (%)76 (14%)
Bone resorption1 (0.5%)0 (0%)0 (%)3 (0.5%)
Pain16 (6%)3 (10%)0 (%)28 (5%)
Swelling0 (0%)0 (0%)0 (%)1 (0.2%)
Abscess formation2 (1%)1 (3%)0 (%)5 (1%)
Dislodged prosthesis5 (2%)1 (3%)0 (%)11 (2%)
Fracture of an abutment7 (3%)1 (3%)0 (%)2 (0.3%)
Prosthesis fracture35 (14%)0(0%)0 (%)25 (5%)
Shade mismatch35 (14%)7 (24%)0 (%)77 (14%)
Contour discrepancies6 (2%)1 (3%)0 (%)19 (3.5%)
Total257 (30.5%)30 (3.5%)0 (0%)551 (66%)

Failure Factors Concerning Brushing Frequency

Table 9: Failure Factors Concerning Brushing Frequency

• Newer prostheses (≤2-4 years): Higher rates of periodontal problems, food impaction, and poor oral hygiene.

• Older prostheses (≥5 years): Higher rates of shade mismatch and contour discrepancies.

Failure Factors≥ 1 year2-4 years≤ 5 years
Periodontal problem16 (18.5%)43 (19%)74 (16%)
Food impaction10 (11.5%)29 (13%)64 (13.5%)
Poor oral hygiene17 (19.5%)44 (19%)86 (18%)
Mobility0 (0%)1 (0.5%)7 (1.5%)
Periapical lesion2 (2%)14 (6%)26 (5.5%)
Secondary caries3 (3.5%)  

Failure Factors Concerning the Age of the Prosthesis

Table 10: Failure Factors Concerning the Age of the Prosthesis

• Lower prostheses: Slightly higher rates of periodontal problems, food impaction, and poor oral hygiene compared to upper prostheses.

Failure FactorsUpperLower
Periodontal problem (gingivitis/periodontitis)69 (18%)63 (15.5%)
Food impaction49 (13%)54 (13%)
Poor oral hygiene75 (19.3%)72 (18%)
Mobility3 (0.7%)5 (1%)
Periapical lesion13 (3.3%)28 (7%)
Secondary caries56 (14.5%)47 (12%)
Bone resorption0 (0%)4 (1%)
Pain17 (4%)31 (8%)
Swelling1 (0.2%)0 (0%)
Abscess formation4 (1%)4 (1%)
Dislodged prosthesis9 (2.5%)8 (2%)
Fracture of an abutment3 (0.7%)0 (0%)
Prosthesis fracture15 (4%)16 (4%)
Shade mismatch56 (14.5%)63 (15.5%)
Contour discrepancies17 (4.3%)9 (2%)
Total387 (49%)404 (51%)

Failure Factors Concerning the Position of the Prosthesis

Table 11: Failure Factors Concerning the Position of the Prosthesis

• Posterior prostheses: Significantly higher rates of failure compared to anterior or anteroposterior prostheses.

Failure FactorsAnteriorPosteriorAnteroposterior
Periodontal problem19 (18%)96 (18%)19 (13%)
Food impaction9 (8.3%)73 (13.5%)21 (14.5%)
Poor oral hygiene22 (20.2%)97 (18%)28 (19.5%)
Mobility3 (2.5%)4 (0.5%)1 (0.5%)
Periapical lesion3 (2.5%)30 (5.5%)9 (6.5%)
Secondary caries16 (15%)66 (12%)20 (14%)
Bone resorption0 (0%)3 (0.5%)1 (0.5%)
Pain3 (2.5%)36 (6.8%)9 (6.5%)
Swelling1 (1%)0 (0%)0 (0%)
Abscess formation2 (2%)4 (0.5%)2 (1.5%)
Dislodged prosthesis3 (2.5%)11 (2%)3 (2%)
Fracture of an abutment0 (0%)1 (0.2%)2 (1.5%)
Prosthesis fracture4 (4%)22 (4%)6 (4%)
Shade mismatch16 (15%)84 (15.5%)18 (12.5%)
Contour discrepancies7 (6.5%)15 (3%)5 (3.5%)
Total108 (14%)542 (68%)144 (18%)

Failure Factors Concerning the Number of Units

Table 12: Failure Factors Concerning the Location of the Prosthesis

• 3-unit prostheses: Highest rates of failure, primarily due to periodontal problems, food impaction, and poor oral hygiene.

Failure Factors1 unit2 units3 units≤ 4 units
Periodontal problem38 (17%)32 (17.5%)41 (17%)23 (15.5%)
Food impaction33 (14.5%)23 (13%)25 (10.5%)23 (15.5%)
Poor oral hygiene38 (17%)34 (19%)44 (18.5%)31 (20.5%)
Mobility2 (1%)2 (1%)3 (1%)1 (0.5%)
Periapical lesion13 (6%)11 (6%)9 (4%)8 (5.5%)
Secondary caries29 (13%)25 (14%)27 (11%)23 (15.5%)
Bone resorption1 (0.5%)2 (1%)0 (0%)1 (0.5%)
Pain11 (5%)9 (5%)20 (8.5%)8 (5.5%)
Swelling0 (0%)0 (0%)1 (0.5%)0 (0%)
Abscess formation1 (0.5%)1 (0.5%)5 (2%)0 (0%)
Dislodged prosthesis4 (2%)3 (1.5%)6 (2.5%)4 (2.5%)
Fracture of an abutment2 (1%)0 (0%)1 (0.5%)0 (0%)
Prosthesis fracture6 (2.5%)6 (3%)13 (5.5%)9 (6%)
Shade mismatch41 (18%)28 (15.5%)33 (14%)15 (10%)
Contour discrepancies5 (2%)6 (3%)10 (4.5%)4 (2.5%)
Total224(26.5%)182(21.5%)283 (34%)150 (18%)

Failure Factors Concerning the Number of Units

Table 13: Failure Factors Concerning the Number of Units

Overall Analysis: The study found that biological factors, such as poor oral hygiene and periodontal disease, were the primary contributors to FPD failure. However, mechanical and aesthetic factors also played a significant role. Factors like age, education level, brushing habits, prosthesis age, position, location, and number of units all influenced the likelihood of FPD failure.

Discussion

This study investigated the factors contributing to FPD failures in a sample of 208 patients in Yemen. Here's a breakdown of the key findings:

• Biological Failures: This study aligns with previous research highlighting biological factors as the primary cause of FPD failures. Poor oral hygiene, periodontal disease, and secondary caries were consistent contributors.

• Mechanical Failures: While less common, mechanical failures, such as fractures and dislodgement, are in line with previous reports.

• Esthetic Failures: Shade mismatch and contour discrepancies were significant aesthetic concerns, consistent with prior studies.

• Oral Hygiene: The strong association between poor oral hygiene and FPD failures is supported by existing literature, emphasizing the importance of preventive care.

• Age and FPD Location: The findings regarding older age and posterior FPD placement being associated with higher failure rates are consistent with previous research.

Contrasting Findings:

• Distribution of Failures: This study deviates from some previous research by finding a higher rate of biological failures compared to mechanical failures. This may be due to variations in study populations, methodologies, or regional differences.

• Number of Units: The lack of a clear relationship between the number of units in an FPD and failure rate contradicts some previous studies. This could be attributed to factors like material quality, fabrication techniques, or patient-specific factors.

Overall, this study provides valuable insights into FPD failures in Yemen and contributes to the growing body of knowledge in this area. While some findings align with previous research, the discrepancies highlight the need for further investigation to understand the complex interplay of factors influencing FPD longevity. Future studies could explore the impact of material selection, fabrication techniques, and patient-specific factors in greater detail.

Conclusions and Recommendations

Limitations

• Radiographic Limitations: The use of two-dimensional radiography may have limited the sensitivity of the study, as compared to three-dimensional imaging, for assessing various parameters. This was due to financial constraints and the desire to minimize patient radiation exposure.

• Age of Prosthesis: The inability to determine the exact age of many prostheses due to patients' lack of recall was a limitation.

Conclusions

Within the limitations of this study, the following conclusions can be drawn:

• Failure Factors: The factors contributing to FPD failures were categorized into three primary groups: biological, mechanical, and aesthetic.

o Biological: Poor oral hygiene, periodontal problems, food impaction, secondary caries, pain, periapical lesions, mobility, abscess formation, and swelling.

o Mechanical: Prosthesis fracture, dislodged prosthesis, fracture of an abutment, and loss of restoration along with abutment teeth.

o Aesthetic: Shade mismatch and contour discrepancies.

• Relationships: There were relationships between failure factors and brushing frequency, number of units, location, and age of the prosthesis.

• No Relationship: No significant relationships were found between failure factors and academic level, gender, or position of the prosthesis (maxillary or mandibular).

• Combined Failures: Some cases exhibited multiple failure reasons, with biological, mechanical, and aesthetic factors contributing in varying combinations.

Recommendations

Recall System: Establishing a proper recall system for patients who have undergone fixed prosthodontic work is recommended to facilitate early detection and management of complications.

Material Evaluation: Further studies are needed to investigate the factors influencing the choice of materials for crown and bridgework within the institution. The materials used can significantly impact the success rate and associated complications of these prostheses.

References

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I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.

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S Munshi

Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.

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Tania Munoz

“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.

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George Varvatsoulias

Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.

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Rui Tao

Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.

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Khurram Arshad

Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.

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Gomez Barriga Maria Dolores

The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.

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Lin Shaw Chin

Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.

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Maria Dolores Gomez Barriga

Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.

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Dr Maria Dolores Gomez Barriga

Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.

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Dr Maria Regina Penchyna Nieto

Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.

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Dr Marcelo Flavio Gomes Jardim Filho

Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”

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Zsuzsanna Bene

Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner

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Dr Susan Weiner