Case Report | DOI: https://doi.org/10.31579/2578-8949/064
Department of Dermatology, University Hospital Hassan II of Fez Morocco.
*Corresponding Author: Mounia Bennani, Department of Dermatology, University Hospital Hassan II of Fez Morocco.
Citation: Bennani M, Ziani J, Elloudi S, Douhi Z, Baybay H, Fatima Z Mernissi (2020). Yellowish plaque on the scalp of a nursling, What’s your Diagnosis?. Journal of Dermatology and Dermatitis.5 (1); Doi:10.31579/2578-8949/064
Copyright: © 2020 Sara Oukarfi, This is an open-access article distributed under the terms of The Creative Commons. Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Received: 01 March 2020 | Accepted: 19 March 2020 | Published: 23 March 2020
Keywords: Juvenile xanthogranuloma; xanthogranulomatous dermal infiltrate; dermoscopy
A 6-month-old girl presented with a 2- month history of a solitary slowly enlarging soft yellow plaque located at the vertex, with no other associated sign
General examination had found a baby in good general condition, toned and reactive, with on dermatological examination a yellow plaque of 3 cm of large roughly oval, with hairy surface (Figure 1)
The dermoscopy had objectified: an orange-yellow background coloring with clouds of xanthomatous deposits (Figure 2).
The rest of the somatic examination was unremarkable
Given the age of the infant, the clinical history, the appearance of the lesion, and the dermoscopy strongly suggestive of the diagnosis, a conservative management was adopted, with the beginning of regression of the lesion in the following year, without the appearance of new injury with a hindsight of four years
Juvenile xanthogranuloma (JXG) is a common form of non-Langerhans cell histiocytosis, mild, with good prognosis , First described by Adamson in 1905[1], its current nomenclature was adopted in 1954.[2] and its manifests as asymptomatic yellow-red papulonodules that usually occur in childhood [3] usually in the first months of life [4] and spontaneously regress within a year of formation.[3] Lesions may be solitary or multiple, and although they are most often found in the skin, they can also develop within other organs [5]
In early stages it is pink to red with a yellow tinge , but with time it acquires a yellow-brown hue and may develop occasional telangiectases on the surface[6]
Because of its benignity and transitory character, it is estimated that it is an underdiagnosed entity and, therefore, of unknown incidence [7]
Extracutaneous involvement is described, and is estimated to occur in 4% of cases, affecting any organ or tissue [8] Risk factors for extracutaneous involvement are age under two years and the presence of multiple lesions [5].
Diagnostic is fundamentally clinical , but dermoscopy can improve diagnostic sensitivity by showing a characteristic orange-yellow background colouration, with ‘clouds’ of paler yellow deposits consistent with a xanthogranulomatous dermal infiltrate. The ‘clouds’ of paler yellow deposits are similar to those seen in sebaceous hyperplasia [3] as in our patient.
The prognosis of patients with exclusively cutaneous involvement is excellent, with spontaneous remission in months or a few years, and relapses are rare.[7]In some cases, a small residual hyperpigmented scar may remain.Surgical removal may be considered only for cosmetic reasons, especially in cases of giant JXG[9]
Dear Editorial Team, Clinical Medical Reviews and Reports. My experience with the journal was highly positive. The peer-review process was rigorous, constructive, and completed in a timely manner. The reviewers provided valuable comments that helped improve the quality and clarity of our manuscript. The editorial office was professional, responsive, and supportive throughout all stages of the publication process. Communication was clear and efficient, and any questions were addressed promptly. Overall, I found the journal to maintain high scientific standards and an excellent publication workflow. I would be pleased to consider submitting future work to this journal. Best wishes from, Elena Popa.
It was my pleasure to submit my testimonial concerning the Reviewer Board of our Scientific Journal “Brain and Neurological Disorders”. The Reviewers focused on some modifications and their contribution was helpful. The ladies of our Editorial Office were also supported my efforts. It was my honor to have such a co-operation and I am looking forward for more collaboration.
Dear Grace Pierce, Editorial Coordinator of Journal of Clinical Research and Reports, Thank you for the speedy and efficient peer review process. I appreciate the fact that your peer reviewers do not take months to respond like with some other journals. I would also like to thank the editorial office for responding quickly to my questions. It is an excellent journal. I plan to submit more manuscripts in the future. Best wishes from, Robert W. McGee
Dear Grace Pierce, Editorial Coordinator of Journal of Clinical Research and Reports, Working with you and your team on our recent publication in JCRR has been a truly wonderful and enjoyable experience. The responses were prompt, and the reviewers were patient, constructive, and highly professional. One reviewer in particular gave me the feeling that a professor was carefully reading and commenting on my coursework, which was deeply touching. The entire process was straightforward and hassle‑free, with no tedious online forms to complete. I highly recommend this journal. Best wishes from, DR Aibing Rao, Head of R&D
I Appreciate the Opportunity to Share my Experience with the Journal of Clinical Research and Reports. The peer review process was timely and constructive, and the feedback provided helped improve the quality of our manuscript. The editorial office was professional, responsive, and supportive throughout the process, ensuring smooth communication and efficient handling of the submission. Overall, it was a positive experience collaborating with your team.
Dear Mercy Grace, Editorial Coordinator of Obstetrics Gynecology and Reproductive Sciences, We would like to express our gratitude for your help at all stages of publishing and editing the article. The editors of the magazine answer all the necessary questions and help at every stage. We will definitely continue to cooperate and publish other works in the Obstetrics Gynecology and Reproductive Sciences! Best wishes from, Alla Konstantinovna Politova,
