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Case Report | DOI: https://doi.org/10.31579/2692-9759/192
Critical Care Unit, Kafr El-Bateekh Central Hospital, Damietta, Egyptian Ministry of Health (MOH), Egypt.
*Corresponding Author: Yasser Mohammed Hassanain Elsayed, Critical Care Unit, Kafr El-Bateekh Central Hospital, Damietta, Egyptian Ministry of Health (MOH), Egypt.
Citation: Hassanain Elsayed YM., (2026), Yasser's Migration Sign with Tail Apex Syndrome in Brugada Syndrome, Variable Interlacing Arrhythmias, and Recurrent Axis Deviation-Cardiovascular Discoveries, Cardiology Research and Reports, 8(2); DOI:10.31579/2692-9759/192
Copyright: © 2026, Yasser Mohammed Hassanain Elsayed. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Received: 19 February 2026 | Accepted: 06 March 2026 | Published: 16 March 2026
Keywords: Yasser's migration sign; Tail apex syndrome; Brugada syndrome; sinusoidal fibrillation; junctional tachycardia; axis deviation; and cardiovascular discoveries
Introduction: Brugada syndrome (BrS) is a rare genetic or inherited disease in which there is abnormal cardiac channelopathy. It is one of the most common inherited primary arrhythmia syndromes. It often presents with arrhythmic syncope or sudden cardiac death. The cardiac axis represents the sum of all depolarization vectors of the heart. The vector analysis determines the direction of the net flow of current through the heart. The cardiac axis deviations have a large differential diagnosis.
Case presentation: A middle-aged married female housewife, patient, was presented to the ICU with junctional tachycardia, diabetes, non-specific chest pain, Brugada syndrome, and past bronchial asthma. Migratory Brugada syndrome, variable interlacing arrhythmias, ECG axis deviations, and mild chest and urinary tract infections in a diabetic patient are the most probable diagnosis. Electrocardiography, oxygenation, chest CT, brain CT, ABG, and echocardiography are the interventions. There is a dramatic clinical, and electrocardiographic improvement had happened.
Conclusion: "Yasser's migration sign" and "Tail Apex Syndrome" are new cardiovascular discoveries. Variable and changeable topical changes in coving-like ST-segment elevations of Brugada syndrome in the ECG throughout the course of the ICU admission are fantastic, a new description. Genetic migrations of Brugada syndrome may be a suggested theory. Amiodarone is suggested as a cause for these different serial changes in axis deviations in the ECG. Variable documented arrhythmias such as junctional tachycardia, sinusoidal AF, and sinus tachycardia are newly reported in Brugada syndrome.
ASD: Atrial septal defect
BrS: Brugada syndrome
ECG: Electrocardiography
ICU: Intensive care unit
JT: Junctional tachycardia
LAD: Left axis deviation
MI: Myocardial infarction
O2: Oxygen
RAD: Right axis deviation
RBBB: Right bundle branch block
SCD: Sudden cardiac death
VF: Ventricular fibrillation
WPW: Wolff-Parkinson-White
Brugada syndrome (BrS) is a rare genetic or inherited disease in which there is abnormal cardiac channelopathy [1]. The BrS was initially described as a new ECG condition in 1992 [2] by Pedro and Josep Brugada [3]. It is one of the most common inherited primary arrhythmia syndromes. It often presents with arrhythmic syncope or sudden cardiac death (SCD) due to polymorphic ventricular tachycardia (PVT) and ventricular fibrillation (VF). Vagotonia or fever is usually a precipitating factor in apparently healthy adults [1]. Ventricular fibrillation and SCD occur in structurally normal hearts. To date, 18 genes have been associated with the disease, with the voltage-gated sodium channel α type V gene (SCN5A) being the most common one to date. However, only 30-35% of diagnosed cases are attributable to pathogenic variants in known genes, emphasizing the need for further genetic studies [4]. The most commonly involved gene is SCN5A, which encodes the cardiac sodium channel [2]. The prevalence of the syndrome (0.01%-0.3%) varies among regions and ethnicities, being the highest in Southeast Asia. BrS is diagnosed by the "coved type" ST-segment elevation ≥2mm followed by a negative T-wave in ≥1 of the right precordial leads V1-V2. The typical electrocardiogram in BrS is often concealed by fluctuations between normal, non-diagnostic, and diagnostic ST-segment patterns in the same patient, thus hindering the diagnosis. Presently, the majority of BrS patients is incidentally diagnosed, and may remain asymptomatic for their lifetime. However, BrS is responsible for 4-12% of all SCDs and for ~20% of SCDs in patients with structurally normal hearts [1]. Sudden cardiac death is linked to the hereditary condition known as Brugada syndrome (BrS), an autosomal dominant heart illness [5]. Identification of an underlying genetic culprit continues to be elusive in the majority of patients, while discord regarding the condition’s underlying pathophysiology also persists, with strong lines of evidence present for both the “depolarization” and “repolarization” hypotheses [6]. Arrhythmic risk is the highest in SCD survivors and in patients with spontaneous BrS electrocardiogram and arrhythmic syncope, but risk stratification for SCD in asymptomatic subjects has not yet been fully defined [1]. The most effective approach to unmasking this diagnostic pattern is the use of ajmaline and flecainide tests, and the most effective intervention to reducing the risk of death is the implantation of a cardioverter defibrillator [4]. Recent achievements have expanded our understanding of the genetics and electrophysiological mechanisms underlying BrS, while radiofrequency catheter ablation may be an effective new approach to treat ventricular tachyarrhythmias in BrS patients with arrhythmic storms [1]. The abnormal heart rhythms seen in those with Brugada syndrome often occur at rest [3].It should also be noted that a type 1 Brugada ECG may also be provoked by a variety of clinical insults and conditions, including myocardial ischemia, metabolic abnormalities, and pectus excavatum [6]. The condition is characterized by ‘coved’ ST-segment elevations in the anterior precordial electrocardiogram leads [3]. Pharmacologic therapy is designed to produce an inward shift in the balance of currents active during the early phases of the right ventricular action potential (AP) and can be used to abort electrical storms or as an adjunct or alternative to device therapy when use of an implantable cardioverter defibrillator is not possible. Isoproterenol, cilostazol, and milrinone boost calcium channel current and drugs like quinidine, bepridil, and the Chinese herb extract Wenxin Keli inhibit the transient outward current, acting to diminish the AP notch and thus to suppress the substrate and trigger for ventricular tachycardia or fibrillation. Radiofrequency ablation of the right ventricular outflow tract epicardium of patients with BrS has recently been shown to reduce arrhythmia vulnerability and the electrocardiographic manifestation of the disease, presumably by destroying the cells with more prominent AP notch [7]. The criteria for diagnosing BrS have evolved since the condition’s initial description, and debate continues regarding the need for additional identifiable clinical features beyond the distinctive electrocardiographic pattern, particularly in cases in which a type 1 pattern is only observed during provocative drug challenge. Criteria for concluding a type 1 ECG pattern require J-point elevation ≥ 2 mm in one or more lead among V1 or V2 positioned in the second, third, or fourth intercostal space, in association with a coved ST-segment morphology, whereas the type 2 pattern requires ≥ 2 mm of J-point elevation in similar lead positions in association with a saddleback ST-segment morphology [8]. The most recent Heart Rhythm Society/European Heart Rhythm Association/Asia Pacific Heart Rhythm Society (HRS/EHRA/APHRS) expert consensus statement indicates that a type 1 Brugada ECG pattern, either spontaneous, fever, or drug-induced, is sufficient to satisfy a diagnosis of BrS [9]. Determining the electrical axis of the heart is an essential step for the initial ECG interpretation [10]. The cardiac axis represents the sum of all depolarization vectors of the heart. The vector analysis determines the direction of the net flow of current through the heart [11]. There are five types of axes: 1. Normal axis (between -30° and +90°), 2. Left axis deviation (LAD: between -30° and -90°), 3. Right axis deviation (RAD: between -90° and 180°), 4. Extreme axis deviation (between +90° and 180° or beyond +100°). 5. Indeterminate axis: the QRS complex is isoelectric or equiphasic in all leads with no dominant QRS deflection [12]. Physiological normal variations, age-related changes, left ventricular hypertrophy (LVH), left bundle branch block (LBBB), left anterior fascicular block (LAFB), inferior myocardial infarction (MI), Wolff-Parkinson-White (WPW) syndrome, premature ventricular complexes (PVCs), ventricular tachycardia (VT), primum atrial septal defect (ASD), endocardial cushion defect, hyperkalemia, emphysema mechanical shift, such as with expiration or raised diaphragm (eg, pregnancy, ascites, abdominal tumor, organomegaly), and paced rhythm are implicated causes in left axis deviation [13-16]. Physiological normal variations such as children and young adults, limb lead reversal of left and right arm electrodes, right ventricular (RV) overload syndromes (acute or chronic), RV hypertrophy (RVH), left posterior fascicular block (LPFB), right bundle branch block (RBBB), lateral MI, WPW syndrome, PVCs, VT, secundum ASD, dextrocardia, left pneumothorax, mechanical shift, such as with inspiration or emphysema, RV strain (eg, pulmonary embolism (PE), pulmonary stenosis (PS), pulmonary hypertension (PHT), chronic pulmonary disease, and cor pulmonale are implicated causes in right axis deviation [13-16]. The physician will be worried if the axis suddenly changed from the last ECG, with chest pain or dyspnea, and ST-segment elevation. New RAD deserves more concern than the left. Sodium channel blockers such as amiodarone can cause RAD of the terminal QRS [17]. The presence of the RBBB, RAD, or LAD may be key for the diagnosis of bifascicular heart block [10].
I report a case of a middle-aged married female housewife, patient, was presented to the ICU with junctional tachycardia, diabetes, non-specific chest pain, migratory Brugada syndrome, and past bronchial asthma with cardiovascular discoveries.
A 41-year-old married female housewife, patient, was presented to the intensive care unit (ICU) with palpitations, acute non-specific chest pain, and dizziness. Cough, headaches, and generalized body pain were associated symptoms. The patient has a history of diabetes mellitus 12 years ago, on long-acting insulin. She also has a history of bronchial asthma 20 years ago on intermittent anti-asthmatic medications. Upon general physical examination, the patient had tachypnea and distressed respiration, with a regular pulse rate (junctional tachycardia (JT) with VR of 165), blood pressure (BP) of 110/80 mmHg, respiratory rate of 25 bpm, a temperature of 36°C, and a pulse oximeter of oxygen (O2) saturation of 97%. No more relevant clinical data were noted during the clinical examination. The patient refused the referral for admission to the intensive care unit (ICU). He was initially managed at the ICU, with a junctional tachycardia, diabetes, non-specific chest pain, and Brugada syndrome. Initially, the patient was treated with O2 inhalation via an oxygen system line (100%, using a normal mask, 5L/min). The initial ECG tracing was performed on the initial presentation to the ICU, with one and a half calibration showing junctional tachycardia, normal axis, and coving-like ST-segment elevations in the aVR, V1, and V2 leads. There is a loose lead artifact in the V5 lead (Figure 1A). The second ECG tracing was taken within 3 minutes of the above ECG tracing, with one and a half calibration showing junctional tachycardia, interlacing of premature junctional complexes in V1 and V2 leads, with the same changes as above. But with AC artifacts and Wavy triple sign (Yasser's sign) in V6 lead (Figure 1B). The patient was treated with amiodarone IV bolus (300 mg IV over 20 minutes, then a continuous IVI at a rate of 1 mg/min for 6 hours). The patient was monitored hourly for vital signs and O2 saturation. The third ECG tracing was taken within 22 hours of the above ECG tracing, with one and a half calibration showing sinusoidal AF, normal axis, and disappearance of the above coving-like ST-segment elevations (Figure 1C). Amiodarone IV was given as a maintained dose, Diltiazem tablets (60mg, OD), SC Enoxaparin 40 mg, OD, and Warfarin tablet (5 mg, OD) were added. There is a new mild fever (temp of 38.5°C), tachypnea, dry cough, and frequent micturition. Urine analysis on the second day of ICU admission showed: pus over 50, RBCs: 10-12, and epithelial cells (++). The fourth ECG tracing was taken within 42 hours of the above ECG tracing, showing sinus tachycardia, normal axis, a coving-like ST-segment elevations in the aVR, V1, and V2 leads (Figure 1D). The fifth ECG tracing was taken within 6 hours of the above ECG tracing, showing sinus tachycardia, right axis deviation, with coving-like ST-segment elevations in I and aVL leads. There is a loose lead artifact in V2 lead (Figure 1E). Cefotaxime vials (1 gm IV BID) and paracetamol (500 mg TID as needed) were added. The sixth ECG tracing was taken within 1 minute of the above ECG tracing, showing sinusoidal AF, right axis deviation, with coving-like ST-segment elevations in the I and aVL leads. There is a loose lead artifact in V2 lead (Figure 1F). The seventh ECG tracing was taken within 1 minute of the above ECG tracing, showing sinusoidal AF, right axis deviation, with coving-like ST-segment elevations in I and aVL leads. There is a loose lead artifact in the V2 lead (Figure 1G). The eighth ECG tracing was taken within 24 hours of the above ECG tracing, showing sinusoidal AF, right axis deviation, with coving-like ST-segment elevations in the I and aVL leads. There is sagged ST-segment depression in the V4-6 leads (Figure 1H). The ninth ECG tracing was taken within 7 hours of the above ECG tracing, showing sinusoidal AF with normal axis (Figure 1I). The tenth ECG tracing was taken within 5 days of the above ECG tracing, with one and a half calibrations, showing junctional tachycardia, left axis deviation, with coving-like ST-segment elevations in the III, aVR, and V1 leads. There is a retrograde P wave in V6 lead (Figure 1J). The eleventh ECG tracing was taken within 8 hours of the above ECG tracing, showing sinusoidal AF, right axis deviation, with coving-like ST-segment elevations in I and aVL leads. There is equivocal QRS in the aVR lead (Figure 1K). The chest X-ray film PA view performed on the initial presentation to the ICU shows tail-like outward apical elongation. There are mild right and left consolidation opacities (Figure 2A). The plain film of chest CT performed on the initial presentation to the ICU showed tail-like outward apical elongation with a narrow lower black recess separating the left diaphragmatic surface and lower surface of the right heart (Figure 2B). Serial cuts of chest CT were done on the initial presentation to the ICU, showing no abnormalities (Figure 2C). Serial cuts of brain CT were done on the initial presentation to the ICU, showing no abnormalities (Figure 2D). The echocardiography was done within 4 days after the ICU presentation, showing tachycardia, mild mitral regurgitation, and a good LV systolic function of an EF of 53% (Figure 3). The initial laboratory: complete blood count (CBC); Hb was 11.3 g/dl, RBCs; 5.37*103/mm3, WBCs; 12.0*103/mm3 (Neutrophils; 53.7 %, Lymphocytes: 36.1%, Monocytes; 8.2%, Eosinophils; 0% and Basophils 0%), Platelets; 327*103/mm3. CRP was 6.0. SGPT was (26.7 U/L). Serum albumen was 4.2 gm/dl. Serum creatinine was (0.97 mg/dl). RBS was (254 mg/dl). D-dimer was 0.3ug/ml. ABG was done in the third day; (PH; 7.41, PCO2; 49.6 mmHg, HCO3; 31.8 mmHg, So2; 96%, and PaO2; 78 mmHg). INR was 1.04 with a prothrombin time of 13.08 seconds. The associated electrolytes in the ABG profile: Plasma sodium was 160 mmol/L. Serum potassium was (3.2 mmol/L). Serum ionized calcium was (1.01 mmol/L). The CBC was repeated in the third day; Hb was 11.2 g/dl, RBCs; 5.33*103/mm3, WBCs; 13.7*103/mm3 (Neutrophils; 67.6 %, Lymphocytes: 27.6%, Monocytes; 4.8%, Eosinophils; 0% and Basophils 0%), Platelets; 322*103/mm3. The troponin initial test was negative. On the ninth day; The CBC: Hb was 10.8 g/dl, RBCs; 5.17*103/mm3, WBCs; 13.8*103/mm3 (Neutrophils; 63.7 %, Lymphocytes: 31.4%, Monocytes; 4.9%, Eosinophils; 0% and Basophils 0%), Platelets; 210*103/mm3. CRP was 12.0. SGPT was (31.0 U/L). Serum creatinine was (0.6 mg/dl). Rheumatoid factor was negative. Migratory Brugada syndrome, variable interlacing arrhythmias, ECG axis deviations, and mild chest and urinary tract infections in a diabetic patient are the most probable diagnosis. Within eleven days of the above at-ICU management, the patient finally showed nearly complete clinical and ECG improvement. The patient was continued on Diltiazem tablets (60 mg, OD), Amiodarone tablets (200 mg, OD), Warfarin (5mg, OD), long-acting insulin, oral calcium, and Vitamin-D preparations for 14 days with further recommended cardiac and urological follow-up.

Figure 1: Serial ECG tracings; A. tracing was done on the initial presentation to the ICU with one and a half calibration, showing junctional tachycardia (of VR 165), normal axis (golden arrows), with coving-like ST-segment elevations in the aVR, V1, and V2 leads (red circles). There is a loose lead artifact in V5 lead (large grey arrow).

Figure 1B: tracing was taken within 3 minutes of the above ECG tracing with one and a half calibrations, showing junctional tachycardia (of VR 159), interlacing of premature junctional complexes in V1 and V2 leads, with the same changes. But with AC artifacts (orange arrows) and Wavy triple sign (Yasser's sign) in V6 lead (light blue arrow).

Figure 1C: tracing was taken within 22 hours of the above ECG tracing, with one and a half calibrations, showing sinusoidal AF (of VR 117; lime arrows and golden circles), normal axis (orange and light blue arrows), and disappearance of the above coving-like ST-segment elevations.

Figure 1D: tracing was taken within 42 hours of the above ECG tracing, showing sinus tachycardia (of VR 123; lime arrows), normal axis (golden arrows and light blue arrows), with coving-like ST-segment elevations in aVR, V1, and V2 leads (red circles).

Figure 1E: tracing was taken within 6 hours of the above ECG tracing, showing sinus tachycardia (of VR 114; lime and pink arrows), right axis deviation (golden arrows and light blue arrows), with coving-like ST-segment elevations in I and aVL leads (orange circles). There is a loose lead artifact in V2 lead (large grey arrow).

Figure 1F: tracing was taken within 1 minute of the above ECG tracing, showing sinusoidal AF (of VR 119; lime and pink arrows), right axis deviation (golden arrows and light blue arrows), with coving-like ST-segment elevations in I and aVL leads (orange circles). There is a loose lead artifact in V2 lead (large grey arrow).

Figure 1G: tracing was taken within 1 minute of the above ECG tracing, showing sinusoidal AF (of VR 111; lime arrows), right axis deviation (golden arrows and light blue arrows), with coving-like ST-segment elevations in I and aVL leads (orange circles). There is a loose lead artifact in V2 lead (large grey arrow).

Figure 1H: tracing was taken within 24 hours of the above ECG tracing, showing sinusoidal AF (of VR 137; lime arrows), right axis deviation (golden arrows and light blue arrows), with coving-like ST-segment elevations in I and aVL leads (orange circles). There is sagged ST-segment depression in V4-6 leads (dark blue arrows).

Figure 1I: ECG Tracing was taken within 7 hours of the above ECG tracing, showing sinusoidal AF (of VR 85; lime arrows, golden, and rosy circles) with normal axis (golden arrows and light blue arrows).

Figure 1J: tracing was taken within 5 days of the above ECG tracing with one and a half calibration, showing junctional tachycardia (of VR 141), left axis deviation (golden arrows and light blue arrows), with coving-like ST-segment elevations in the III, aVR, and V1 leads (orange circles). There is a retrograde P wave in V6 lead (lime arrow).

Figure 1K: tracing was taken within 8 hours of the above ECG tracing, showing sinusoidal AF (of VR 108; lime arrows), right axis deviation (orange arrows), with coving-like ST-segment elevations in I and aVL leads (golden circles). There is equivocal QRS in the aVR lead (light Blue Square).

Figure 2A: Plain chest X-ray film, PA view was taken on the initial presentation to the ICU, showing tail-like outward apical elongation (dark blue circle and golden arrow). There are mild right (yellow arrow) and left (lime arrow) consolidation opacities. B. Plain film of chest CT was taken on the initial presentation to the ICU, showing tail-like outward apical elongation (yellow square and lime arrow) with a narrow lower black recess separating the left diaphragmatic surface and lower surface of the right heart (small white arrow). C. Serial cuts of chest CT, showing no abnormalities. D. Serial cuts of brain CT, showing no abnormalities.

Figure 3: Echocardiography was taken within 4 days after the ICU presentation, showing tachycardia, mild mitral regurgitation (lime arrow), and a good LV systolic function of an EF of 53% (lime-rectangular).
Overview: A middle-aged married female housewife, patient, was presented to the ICU with junctional tachycardia, diabetes, non-specific chest pain, Brugada syndrome, and past bronchial asthma. The primary objective for my case study was the presence of a middle-aged married female housewife, patient, with junctional tachycardia, diabetes, non-specific chest pain, Brugada syndrome, and past bronchial asthma in the ICU. The secondary objective for my case study was the question of how to manage the case. Mild chest and urinary tract infections were associated with the condition (Figures 2A-2B). There were variable associated arrhythmias throughout the course of the ICU admission. It started with junctional tachycardia (Figures 1A-1B), then sinusoidal AF (Figure 1C), then sinus tachycardia (Figures 1D-1E), then sinusoidal AF (Figures 1F-1I), then junctional tachycardia (Figures 1J-1K). There were also different serial changes in axis deviations in the ECG in the course of the ICU admission. It started with normal axis (Figures 1A-1D), then right axis deviation (Figures 1E-1H), then normal axis (Figure 1I), then left axis deviation (Figure 1J), then right axis deviation (Figure 1K). Indeed, although there is no clear known cause for these different serial changes in axis deviations in the ECG, Amiodarone is suggested as the cause [17]. Naranjo's probability scale was used to assess the probable relationship between these different serial changes in axis deviations and the causative agent, Amiodarone. Naranjo's probability scale in the current case study was +8. It means that there was a probable relationship between the serial changes in axis deviations and the causative Amiodarone (Table 1).

Table 1: Naranjo Algorithm-Adverse Drug Reaction (ADR) Probability Scale in the case report.
There were also variable and changeable topical changes in coving-like ST-segment elevations of Brugada syndrome in the ECG in the course of the ICU admission. It started with coving-like ST-segment elevations in aVR, V1, and V2 leads (Figures 1A-1D), then coving-like ST-segment elevations in I and aVL leads (Figures 1E-1H), then the normal ST-segment in all the
above leads (Figure 1I), then coving-like ST-segment elevations in III, aVR, and V1 leads (Figure 1J), then coving-like ST-segment elevations in I and aVL leads (Figure 1K). These transitions in coving-like ST-segment elevations from one specific lead to another specific lead are a new description regarding Brugada syndrome. So, it is named as "Yasser's migration sign" (Figure 4).

Figure 4: Graphical presentation of Yasser's migration sign and Tail apex syndrome.
There is no known mechanism for these migrations. Genetic migrations of Brugada syndrome may be a suggested theory. Plain chest X-ray film, PA view showing tail-like outward apical elongation with a narrow lower black recess separating the left diaphragmatic surface and lower surface of the right heart. This tail-like outward apical elongation is also newly described. In parallel to these axis deviations and transitions in coving-like ST-segment elevations from one specific lead to another specific ones are new description regarding Brugada syndrome is provided. It may be named as "Tail Apex Syndrome" (Figure 4). Acute pulmonary embolism is the most implicated differential diagnosis. The d-dimer against it. I can’t compare the current case with similar conditions. There are no similar or known cases with the same management for near comparison. The only limitation of the current study was the unavailability of genetic analysis for Brugada syndrome.
"Yasser's migration sign" and "Tail Apex Syndrome" are new cardiovascular discoveries. Variable and changeable topical changes in coving-like ST-segment elevations of Brugada syndrome in the ECG throughout the course of the ICU admission are fantastic, a new description. Genetic migrations of Brugada syndrome may be a suggested theory. Amiodarone is suggested as a cause for these different serial changes in axis deviations in the ECG. Variable documented arrhythmias such as junctional tachycardia, sinusoidal AF, and sinus tachycardia are newly reported in Brugada syndrome.
There are no conflicts of interest.
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We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.
I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.
I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.
I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.
Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.
“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.
Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.
The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.
Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.
My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.
My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.
I would like to offer my testimony in the support. I have received through the peer review process and support the editorial office where they are to support young authors like me, encourage them to publish their work in your esteemed journals, and globalize and share knowledge globally. I really appreciate your journal, peer review, and editorial office.
Dear Agrippa Hilda- Editorial Coordinator of Journal of Neuroscience and Neurological Surgery, "The peer review process was very quick and of high quality, which can also be seen in the articles in the journal. The collaboration with the editorial office was very good."
I would like to express my sincere gratitude for the support and efficiency provided by the editorial office throughout the publication process of my article, “Delayed Vulvar Metastases from Rectal Carcinoma: A Case Report.” I greatly appreciate the assistance and guidance I received from your team, which made the entire process smooth and efficient. The peer review process was thorough and constructive, contributing to the overall quality of the final article. I am very grateful for the high level of professionalism and commitment shown by the editorial staff, and I look forward to maintaining a long-term collaboration with the International Journal of Clinical Case Reports and Reviews.
To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.
"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".
I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.
Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.
We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.
My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.
To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina
Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.
Dear Ashley Rosa, Editorial Coordinator of the journal - Psychology and Mental Health Care. " The process of obtaining publication of my article in the Psychology and Mental Health Journal was positive in all areas. The peer review process resulted in a number of valuable comments, the editorial process was collaborative and timely, and the quality of this journal has been quickly noticed, resulting in alternative journals contacting me to publish with them." Warm regards, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. I appreciate the journal (JCCI) editorial office support, the entire team leads were always ready to help, not only on technical front but also on thorough process. Also, I should thank dear reviewers’ attention to detail and creative approach to teach me and bring new insights by their comments. Surely, more discussions and introduction of other hemodynamic devices would provide better prevention and management of shock states. Your efforts and dedication in presenting educational materials in this journal are commendable. Best wishes from, Farahnaz Fallahian.
Dear Maria Emerson, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. I am delighted to have published our manuscript, "Acute Colonic Pseudo-Obstruction (ACPO): A rare but serious complication following caesarean section." I want to thank the editorial team, especially Maria Emerson, for their prompt review of the manuscript, quick responses to queries, and overall support. Yours sincerely Dr. Victor Olagundoye.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. Many thanks for publishing this manuscript after I lost confidence the editors were most helpful, more than other journals Best wishes from, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Agrippa Hilda, Editorial Coordinator, Journal of Neuroscience and Neurological Surgery. The entire process including article submission, review, revision, and publication was extremely easy. The journal editor was prompt and helpful, and the reviewers contributed to the quality of the paper. Thank you so much! Eric Nussbaum, MD
Dr Hala Al Shaikh This is to acknowledge that the peer review process for the article ’ A Novel Gnrh1 Gene Mutation in Four Omani Male Siblings, Presentation and Management ’ sent to the International Journal of Clinical Case Reports and Reviews was quick and smooth. The editorial office was prompt with easy communication.
Dear Erin Aust, Editorial Coordinator, Journal of General Medicine and Clinical Practice. We are pleased to share our experience with the “Journal of General Medicine and Clinical Practice”, following the successful publication of our article. The peer review process was thorough and constructive, helping to improve the clarity and quality of the manuscript. We are especially thankful to Ms. Erin Aust, the Editorial Coordinator, for her prompt communication and continuous support throughout the process. Her professionalism ensured a smooth and efficient publication experience. The journal upholds high editorial standards, and we highly recommend it to fellow researchers seeking a credible platform for their work. Best wishes By, Dr. Rakhi Mishra.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. The peer review process of the journal of Clinical Cardiology and Cardiovascular Interventions was excellent and fast, as was the support of the editorial office and the quality of the journal. Kind regards Walter F. Riesen Prof. Dr. Dr. h.c. Walter F. Riesen.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. Thank you for publishing our article, Exploring Clozapine's Efficacy in Managing Aggression: A Multiple Single-Case Study in Forensic Psychiatry in the international journal of clinical case reports and reviews. We found the peer review process very professional and efficient. The comments were constructive, and the whole process was efficient. On behalf of the co-authors, I would like to thank you for publishing this article. With regards, Dr. Jelle R. Lettinga.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, I would like to express my deep admiration for the exceptional professionalism demonstrated by your journal. I am thoroughly impressed by the speed of the editorial process, the substantive and insightful reviews, and the meticulous preparation of the manuscript for publication. Additionally, I greatly appreciate the courteous and immediate responses from your editorial office to all my inquiries. Best Regards, Dariusz Ziora
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation, Auctores Publishing LLC, We would like to thank the editorial team for the smooth and high-quality communication leading up to the publication of our article in the Journal of Neurodegeneration and Neurorehabilitation. The reviewers have extensive knowledge in the field, and their relevant questions helped to add value to our publication. Kind regards, Dr. Ravi Shrivastava.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, Auctores Publishing LLC, USA Office: +1-(302)-520-2644. I would like to express my sincere appreciation for the efficient and professional handling of my case report by the ‘Journal of Clinical Case Reports and Studies’. The peer review process was not only fast but also highly constructive—the reviewers’ comments were clear, relevant, and greatly helped me improve the quality and clarity of my manuscript. I also received excellent support from the editorial office throughout the process. Communication was smooth and timely, and I felt well guided at every stage, from submission to publication. The overall quality and rigor of the journal are truly commendable. I am pleased to have published my work with Journal of Clinical Case Reports and Studies, and I look forward to future opportunities for collaboration. Sincerely, Aline Tollet, UCLouvain.
Dear Ms. Mayra Duenas, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. “The International Journal of Clinical Case Reports and Reviews represented the “ideal house” to share with the research community a first experience with the use of the Simeox device for speech rehabilitation. High scientific reputation and attractive website communication were first determinants for the selection of this Journal, and the following submission process exceeded expectations: fast but highly professional peer review, great support by the editorial office, elegant graphic layout. Exactly what a dynamic research team - also composed by allied professionals - needs!" From, Chiara Beccaluva, PT - Italy.
Dear Maria Emerson, Editorial Coordinator, we have deeply appreciated the professionalism demonstrated by the International Journal of Clinical Case Reports and Reviews. The reviewers have extensive knowledge of our field and have been very efficient and fast in supporting the process. I am really looking forward to further collaboration. Thanks. Best regards, Dr. Claudio Ligresti
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation. “The peer review process was efficient and constructive, and the editorial office provided excellent communication and support throughout. The journal ensures scientific rigor and high editorial standards, while also offering a smooth and timely publication process. We sincerely appreciate the work of the editorial team in facilitating the dissemination of innovative approaches such as the Bonori Method.” Best regards, Dr. Matteo Bonori.
I recommend without hesitation submitting relevant papers on medical decision making to the International Journal of Clinical Case Reports and Reviews. I am very grateful to the editorial staff. Maria Emerson was a pleasure to communicate with. The time from submission to publication was an extremely short 3 weeks. The editorial staff submitted the paper to three reviewers. Two of the reviewers commented positively on the value of publishing the paper. The editorial staff quickly recognized the third reviewer’s comments as an unjust attempt to reject the paper. I revised the paper as recommended by the first two reviewers.
Dear Maria Emerson, Editorial Coordinator, Journal of Clinical Research and Reports. Thank you for publishing our case report: "Clinical Case of Effective Fetal Stem Cells Treatment in a Patient with Autism Spectrum Disorder" within the "Journal of Clinical Research and Reports" being submitted by the team of EmCell doctors from Kyiv, Ukraine. We much appreciate a professional and transparent peer-review process from Auctores. All research Doctors are so grateful to your Editorial Office and Auctores Publishing support! I amiably wish our article publication maintained a top quality of your International Scientific Journal. My best wishes for a prosperity of the Journal of Clinical Research and Reports. Hope our scientific relationship and cooperation will remain long lasting. Thank you very much indeed. Kind regards, Dr. Andriy Sinelnyk Cell Therapy Center EmCell
Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. It was truly a rewarding experience to work with the journal “Clinical Cardiology and Cardiovascular Interventions”. The peer review process was insightful and encouraging, helping us refine our work to a higher standard. The editorial office offered exceptional support with prompt and thoughtful communication. I highly value the journal’s role in promoting scientific advancement and am honored to be part of it. Best regards, Meng-Jou Lee, MD, Department of Anesthesiology, National Taiwan University Hospital.
Dear Editorial Team, Journal-Clinical Cardiology and Cardiovascular Interventions, “Publishing my article with Clinical Cardiology and Cardiovascular Interventions has been a highly positive experience. The peer-review process was rigorous yet supportive, offering valuable feedback that strengthened my work. The editorial team demonstrated exceptional professionalism, prompt communication, and a genuine commitment to maintaining the highest scientific standards. I am very pleased with the publication quality and proud to be associated with such a reputable journal.” Warm regards, Dr. Mahmoud Kamal Moustafa Ahmed
Dear Maria Emerson, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews’, I appreciate the opportunity to publish my article with your journal. The editorial office provided clear communication during the submission and review process, and I found the overall experience professional and constructive. Best regards, Elena Salvatore.
Dear Mayra Duenas, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews Herewith I confirm an optimal peer review process and a great support of the editorial office of the present journal
Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. I am really grateful for the peers review; their feedback gave me the opportunity to reflect on the message and impact of my work and to ameliorate the article. The editors did a great job in addition by encouraging me to continue with the process of publishing.
Dear Cecilia Lilly, Editorial Coordinator, Endocrinology and Disorders, Thank you so much for your quick response regarding reviewing and all process till publishing our manuscript entitled: Prevalence of Pre-Diabetes and its Associated Risk Factors Among Nile College Students, Sudan. Best regards, Dr Mamoun Magzoub.
International Journal of Clinical Case Reports and Reviews is a high quality journal that has a clear and concise submission process. The peer review process was comprehensive and constructive. Support from the editorial office was excellent, since the administrative staff were responsive. The journal provides a fast and timely publication timeline.
Dear Mayra Duenas, Editorial Coordinator of the journal IJCCR, I write here a little on my experience as an author submitting to the International Journal of Clinical Case Reports and Reviews (IJCCR). This was my first submission to IJCCR and my manuscript was inherently an outsider’s effort. It attempted to broadly identify and then make some sense of life’s under-appreciated mysteries. I initially had responded to a request for possible submissions. I then contacted IJCCR with a tentative topic for a manuscript. They quickly got back with an approval for the submission, but with a particular requirement that it be medically relevant. I then put together a manuscript and submitted it. After the usual back-and-forth over forms and formality, the manuscript was sent off for reviews. Within 2 weeks I got back 4 reviews which were both helpful and also surprising. Surprising in that the topic was somewhat foreign to medical literature. My subsequent updates in response to the reviewer comments went smoothly and in short order I had a series of proofs to evaluate. All in all, the whole publication process seemed outstanding. It was both helpful in terms of the paper’s content and also in terms of its efficient and friendly communications. Thank you all very much. Sincerely, Ted Christopher, Rochester, NY.
Dear Grace Pierce, Editorial Coordinator of the journal IJCCR, I had a very positive experience with Auctores - Journal throughout the publication process. The Editorial Team was highly responsive, professional, and supportive at every stage. I would like to extend my sincere thanks to the Editor: Grace Pierce, for her guidance and assistance. The peer-review process was smooth and constructive, helping improve the quality of my work. I would gladly recommend Auctores Journal to fellow researchers and authors. Dr. SABITA SINHA, Medical Oncologist, MD (Electro Homeopathy).
Dear Maria Emerson, Editorial Coordinator of - Journal of Clinical Research and Reports. ''I am pleased to provide this testimonial following the publication of our recent case report in this journal. The peer review process was rigorous, constructive, thorough, and conducted in a timely manner. The reviewers’ comments were thoughtful, detailed, and highly constructive, contributing substantially to the refinement, clarity, and scientific robustness of our manuscript. The process was conducted with professionalism and academic integrity throughout. The support provided by the editorial office was exemplary. Communication was consistently prompt, clear, and courteous at all stages of the submission and publication process. The editorial team demonstrated a high level of organization and responsiveness, ensuring that all queries were addressed efficiently and that the process remained transparent and well-coordinated. The overall quality of the journal is reflected in its strong editorial standards, commitment to scientific excellence, and dedication to publishing clinically meaningful research. It has been a privilege to publish our work in this journal, and we would welcome the opportunity to contribute further in the future.'' Best wishes from, Dr. Efstratios Trogkanis, Cardiologist.
Dear Reader: We have published several articles in the Auctores Publishing, LLC, journal, Clinical Medical Reviews and Reports in recent years (CMRR). This is an ‘open access’ journal and the following are our observations. From the initial invitation to submit an article, to the final edits of galley proofs, we have found CMRR personnel to be professional, responsive, rapid and thorough. This entire process begins with Catherine Mitchell, Editorial Coordinator. She is simply outstanding, and, I believe, unparalleled in her capacity. I cannot imagine a more responsive and dedicated Editorial Coordinator. As I read the dates and timing of her correspondence with us, it seems that she never sleeps. I hope Auctores Publishing, LLC, appreciates her efforts as much as these authors do. Thank you to Auctores Publishing, LLC, to the Editorial Staff/Board, and to Catherine Mitchell from a grateful author(s).
Dear Maria Emerson, Editorial Coordinator of International Journal of Clinical Case Reports and Reviews, What distinguishes International Journal of Clinical Case Report and Review is not only the scientific rigor of its publications, but the intellectual climate in which research is evaluated. The submission process is refreshingly free of unnecessary formal barriers and bureaucratic rituals that often complicate academic publishing without adding real value. The peer-review system is demanding yet constructive, guided by genuine scientific dialogue rather than hierarchical or authoritarian attitudes. Reviewers act as collaborators in improving the manuscript, not as gatekeepers imposing arbitrary standards. This journal offers a rare balance: high methodological standards combined with a respectful, transparent, and supportive editorial approach. In an era where publishing can feel more burdensome than research itself, this platform restores the original purpose of peer review — to refine ideas, not to obstruct them Prof. Perlat Kapisyzi, FCCP PULMONOLOGIST AND THORACIC IMAGING.