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Review Article | DOI: https://doi.org/10.31579/2688-7517/164
Clinical Pharmacist, Candidate of Biological Sciences in Pharmacology and Clinical Pharmacology, Member of the Global Academy of Education in Clinical Pharmacy Russia
*Corresponding Author: Dmitrieva Elena Germanovna, Clinical Pharmacist, Candidate of Biological Sciences in Pharmacology and Clinical Pharmacology, Member of the Global Academy of Education in Clinical Pharmacy Russia
Citation: Dmitrieva E. Germanovna, (2024), Weak legs syndrome and other side effects of the use of drugs to reduce blood pressure in Russia Dmitrieva Elena Germanovna, J. Pharmaceutics and Pharmacology Research, 7(3); DOI:10.31579/2688-7517/164
Copyright: © 2024, Dmitrieva Elena Germanovna. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 30 December 2023 | Accepted: 15 January 2024 | Published: 12 February 2024
Keywords: blood pressure; syndrome; autoimmune diseases; weak legs
In Russia, drugs are used to reduce pressure poorly purified in production (moxonidine, captopril, amlodipine, losartan, valsartan and others).
Tinnitus in the left ear, increased bilirubin, hyperemia of the face, palms and feet.
In the clinical practice of a Clinical Pharmacist, there are cases of side effects of drugs to reduce blood pressure
Treated by neurologists
In Russia, drugs are used to reduce pressure poorly purified in production (moxonidine, captopril, amlodipine, losartan, valsartan and others).
Tinnitus in the left ear, increased bilirubin, hyperemia of the face, palms and feet.
In the clinical practice of a Clinical Pharmacist, there are cases of side effects of drugs to reduce blood pressure. Sartans especially of the 1st generation (lorista, losartan, valsartan) can cause pain in the lumbar region and numbness and weakness of the legs, which is consistent with the mandatory cancellation of these drugs.
Direct, indirect, total bilirubin increases by 2 times if you take long-term sartans and other drugs to reduce blood pressure. But sartans prevail.
When using large doses of any drugs to reduce blood pressure, tinnitus phenomena often occur (beating in the left ear), which often affects the absence of normal sleep at night.
myography tests, general blood tests.
The study observed: 55-60-year-old 20 women using drugs to reduce blood pressure.
There are known drugs that give weakness in the legs.
But there are also groups of antihypertensive drugs that can cause the same syndrome.
Side effects of medications
The following are some medications and treatments that can lead to weakness in the legs by affecting the leg muscles.
Cholesterol-lowering medications, such as statins
Some types of chemotherapy for cancer or autoimmune diseases
Anti-inflammatory drugs such as steroids
Anticoagulants
Treatment at home
All causes of leg weakness should be evaluated by a medical professional; however, if the leg weakness was gradual or related to injury or damage, some home treatments may help while you wait for a doctor's examination.
Rest: Some causes of weakness in the legs, especially those related to injury or strain, improve with rest.
Exercise: While some causes of leg weakness improve with rest, others, such as weakness due to prolonged bed rest or immobility, may improve with gradual exercise.
When to see a doctor
Since weakness in both legs can be a sign of a serious problem, weakness in the legs should always prompt a visit to the doctor. However, the urgency with which you should see a doctor depends on some factors, such as the duration, severity and time of the onset of your symptoms. Make an appointment with a primary care provider if you notice the following:
Constant weakness in the legs
Increased weakness in the legs
Weakness in the legs associated with other symptoms: increased fatigue, unexplained weight loss and/or persistent headaches damage).
The syndrome manifests itself by the type of polyneuritis (axonal-demyelinating type of motor fiber
Electro neuromotor graphic examination (ENVG)
When is it urgent?
You should see a doctor immediately if your leg weakness is associated with any of the following symptoms or factors:
Fever and/or chills
Sudden onset
Paralysis of the legs (inability to move the legs)
Numbness of the legs
Numbness of the hands
Vision problems
Balancing issues
Speech problems
Weak legs syndrome is detected in many elderly people with various diseases - diabetes mellitus, hypotension, as well as with secondary diseases - when using drugs from the group of cardiovascular drugs, in particular, when using large doses of drugs to reduce pressure. In Russia, this syndrome is treated only in Moscow. In the regions of Russia, patients are forced to suffer without adequate medical care.
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