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Viruses and Leukaemia, Is leukaemia preventable?

opinion | DOI: https://doi.org/10.31579/2640-1053/208

Viruses and Leukaemia, Is leukaemia preventable?

  • Hilary Denis Solomons

P.O. Box 64203, Highlands North, 203, South Africa.

*Corresponding Author: Hilary Denis Solomons, P.O. Box 64203, Highlands North, 203, South Africa.

Citation: Hilary Denis Solomons (2024), Viruses and Leukaemia, Is leukaemia preventable? J. Cancer Research and Cellular Therapeutics, 8(5); DOI:10.31579/2640-1053/208

Copyright: © 2024, Hilary Denis Solomons, this is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Received: 01 September 2024 | Accepted: 09 September 2024 | Published: 18 September 2024

Keywords: viruses; leukaemia: genome; antiviral agents

Abstract

The Human T-lymphotropic virus Type 1 (HTLV-I) is a human RNA retrovirus that is known to cause a type of cancer, referred to as adult T-cell leukaemia and lymphoma, and a demyelinating disease called HTLV-I associated myelopathy / tropical spastic paraparesis (HAM/TSP).

Summery

The Human T-lymphotropic virus Type 1 (HTLV-I) is a human RNA retrovirus that is known to cause a type of cancer, referred to as adult T-cell leukaemia and lymphoma, and a demyelinating disease called HTLV-I associated myelopathy / tropical spastic paraparesis (HAM/TSP).

HTLV-I is one of a group of closely related primate T lymphocytic viruses (PTLVs).

Members of this family that infect old-world primates are called Simian T-lymphotropic viruses.

Todate, four types of HTLVs (HTLV-I, HTLV- II, HTLV_III, and HTLV-IV), have been identified. The HTLVs arebelieved to originate from interspecies transmission of STLVs.

The original name for HIV, the virus that causes AIDS, was HTLV-III; this term is no longer in use. (1). (http:/medical-dictionary, thefreedictionary.com/HTLV-III.)

The HTLV_I genome is diploid, composed of two copies of a single-stranded RNA virus whose genome is copied into a double-stranded DNA form that integrates into the host cell genome, at which point the virus is referred as provirus.

A closely related virus is bovine leukaemia virus BLV.

This begs the question if all leukaemias are virally related are leukaemias preventable with or through the use of antiviral agents.

References

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