Research Article | DOI: https://doi.org/10.31579/2641-0419/588
1Faculty of Medicine, Cheikh Anta Diop University, Dakar, Senegal.
2Department of Cardiac Rehabilitation, Ibra Mamadou Wane Medical Center, Dakar, Senegal.
3Cardiology Department, Dalal Jamm Hospital, Dakar, Senegal.
4Cardiology Department, Aristide Le Dantec Hospital, Dakar, Senegal.
5Cardiology Department, Idrissa Pouye General Hospital, Dakar, Senegal.
*Corresponding Author: Ngone Diaba Gaye, Faculty of Medicine, Cheikh Anta Diop University, Dakar, Senegal
Citation: Ngone D. Gaye, Joseph S. Mingou, Soumia Benaammouch, Malick Ndiaye, Marguerite T. Diouf, et al, (2026), Thrombolysis in ST-segment elevation acute coronary syndrome at Grand-Yoff General Hospital, Dakar, Senegal, J Clinical Cardiology and Cardiovascular Interventions, 9(9); DOI:10.31579/2641-0419/588
Copyright: © 2026, Ngone Diaba Gaye. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Received: 17 July 2026 | Accepted: 27 July 2026 | Published: 05 August 2026
Keywords: acute coronary syndrome; ST-segment elevation; thrombolysis; streptokinase; senegal
Introduction : Acute coronary syndrome with persistent ST-segment elevation (STEMI) is a major cardiovascular emergency. Its prognosis depends closely on the rapidity of myocardial reperfusion. When primary angioplasty is not available within the recommended timeframes, thrombolysis remains an essential strategy, particularly in resource-limited countries. The objectives of this study were to evaluate thrombolysis in STEMI in the Cardiology Department of Grand-Yoff General Hospital, Dakar, to describe the epidemiological, clinical and paraclinical characteristics of thrombolysed patients, and to analyse thrombolysis outcomes, complications and prognostic factors.
Methods : This was a retrospective, descriptive and analytical study conducted from 1 January 2021 to 31 December 2022 in the Cardiology Department of Grand-Yoff General Hospital. All patients admitted for STEMI during the study period who received thrombolytic therapy were included. Non-thrombolysed patients, as well as lost or unusable medical records, were not included. The diagnosis was based on clinical and electrocardiographic findings. The effectiveness of thrombolysis was assessed according to classical reperfusion criteria: relief of pain, regression of ST-segment elevation by at least 50%, and the possible presence of reperfusion arrhythmias. Data were analysed using Epi Info 7.2 and Excel 2016, with statistical significance set at p<0.05.
Results : During the study period, 1,158 patients were hospitalised, including 110 for STEMI, corresponding to a hospital prevalence of 9.49%. Among them, 76 patients received thrombolysis, giving a thrombolysis rate of 69.09%. Mean age was 57.98±12.99 years, with a range from 27 to 81 years. Men accounted for 72.37%, with a sex ratio of 2.61. The main cardiovascular risk factors were male sex (72.36%), risk-associated age (71.05%), smoking (42.11%), hypertension (38.16%), physical inactivity (26.32%) and diabetes (21.05%). Overall, 85.53% of patients had at least two cardiovascular risk factors. Mean admission delay was 5.43 hours. Typical anginal pain was present in 86.84% of cases. Echocardiography showed segmental wall motion abnormalities in 86.96% of patients, with a mean left ventricular ejection fraction of 49.58%. All patients received streptokinase. Mean thrombolysis delay was 6.03 hours. Successful thrombolysis was observed in 39.47%, while failure occurred in 60.53%. Haemorrhagic complications were found in 11.84%, with no haemorrhagic stroke. In-hospital mortality was 5.26%. Factors associated with mortality were Killip class IV, heart rate >100 beats/min and fasting blood glucose >3 g/L.
Conclusion : played a central role in the management of STEMI at Grand-Yoff General Hospital. However, late presentation and delayed thrombolysis were associated with a high failure rate. These findings highlight the need to strengthen reperfusion pathways, reduce prehospital delays and develop a pharmaco-invasive strategy adapted to the Senegalese context.
Acute coronary syndrome with persistent ST-segment elevation (STEMI) is a major cardiovascular emergency, most often secondary to acute occlusion of a coronary artery by a thrombus developing on a ruptured or eroded atherosclerotic plaque [1–3]. It represents one of the most severe manifestations of ischaemic heart disease and remains associated with high morbidity and mortality despite diagnostic and therapeutic advances. The prognosis depends closely on the rapidity of myocardial reperfusion, as the duration of coronary occlusion determines the extent of myocardial necrosis and the risk of heart failure, arrhythmias and death [4–7].
The therapeutic strategy for STEMI is based on the earliest possible restoration of effective coronary blood flow. Primary angioplasty is the reference reperfusion strategy when it can be performed within the recommended timeframes by an experienced team [4,5]. However, in many resource-limited countries, continuous access to coronary angiography and primary angioplasty remains insufficient. In this context, thrombolysis remains an essential strategy, particularly when the expected delay to angioplasty exceeds guideline recommendations [6–8].
The effectiveness of fibrinolysis depends on several factors, including the pain-to-thrombolysis delay, the drug used, the infarct territory, the initial haemodynamic status, associated antithrombotic therapy and the possibility of a subsequent pharmaco-invasive strategy [9–14]. The earlier it is administered, the higher the likelihood of reperfusion. Conversely, delayed thrombolysis is associated with a higher failure rate and an increased risk of complications.
In sub-Saharan Africa, STEMI is becoming increasingly frequent in a context of epidemiological transition and rising cardiovascular risk factors [15–18]. In Senegal, data specifically evaluating thrombolysis remain limited. The main objective of this study was to assess thrombolysis in STEMI in the Cardiology Department of Grand-Yoff General Hospital, Dakar. The specific objectives were to describe the epidemiological, clinical and paraclinical characteristics of thrombolysed patients, determine the modalities of thrombolysis, and analyse its outcomes, complications and prognostic factors.
This was a retrospective, descriptive and analytical study conducted over a two-year period, from 1 January 2021 to 31 December 2022, in the Cardiology Department of Grand-Yoff General Hospital, Dakar. The department includes an inpatient unit, a cardiac intensive care unit and a functional investigations unit. Patients were initially received in the emergency department, where the diagnosis was made and emergency investigations were performed, before admission to the Cardiology Department for treatment.
The study included medical records of patients hospitalised for STEMI who received thrombolytic therapy. All patients admitted for STEMI during the study period and treated with thrombolysis were included. Patients admitted for STEMI who did not receive thrombolysis, as well as lost or unusable medical records, were not included. The diagnosis of STEMI was based on clinical and electrocardiographic findings, particularly anginal chest pain associated with persistent ST-segment elevation or recent left bundle branch block compatible with acute myocardial infarction [1,4,5].
The data collected included sociodemographic characteristics, cardiovascular risk factors, medical history, place of origin, mode and delay of admission, treatment received before admission, symptoms, clinical parameters, Killip class, and electrocardiographic, biological, echocardiographic and coronary angiographic findings. Admission delay was defined as the time between onset of chest pain and arrival at the department. Thrombolysis delay was defined as the time between onset of chest pain and initiation of thrombolytic therapy.
The effectiveness of thrombolysis was assessed using classical reperfusion criteria: pain relief within 60 to 90 minutes, regression of ST-segment elevation by at least 50%, and the possible occurrence of benign ventricular reperfusion arrhythmias [4,5,9]. Haemorrhagic events, allergic reactions, in-hospital complications and mortality were analysed. Data were collected using a survey form, then entered and analysed with Epi Info 7.2 and Excel 2016. Bivariate analysis used the chi-square test, with statistical significance set at p<0>
During the study period, 1,158 patients were hospitalised in the Cardiology Department of Grand-Yoff General Hospital. Among them, 110 cases of STEMI were recorded, corresponding to a hospital prevalence of 9.49%. Of these patients, 76 received thrombolysis, giving a thrombolysis rate of 69.09% (Figure 1). Patients who did not receive thrombolysis had either presented beyond the recommended time window or had a contraindication to fibrinolysis.
Figure 1: Thrombolysis outcome among STEMI patients (n=76)
The mean age of thrombolysed patients was 57.98±12.99 years, with a range from 27 to 81 years. Men were predominant, with 55 cases (72.37%), compared with 21 women (27.63%), giving a male-to-female sex ratio of 2.61. The 55–65-year age group was the most represented. Most patients came from urban areas (85.53%). Regarding occupation, 42.11% were self-employed and 21.05% were retired. Financial coverage was mainly based on patients’ own resources (44.74%) or support from a third party (42.11%) (Table 1).
| Variable | Number / value | Percentage / detail |
| Patients hospitalised in cardiology | 1158 | — |
| STEMI cases | 110 | 9.49% of hospitalisations |
| Thrombolysed patients | 76 | 69.09% of STEMI cases |
| Mean age | 57.98 ± 12.99 years | Range: 27–81 years |
| Most represented age group | 55–65 years | 30.26% |
| Men | 55 | 72.37% |
| Women | 21 | 27.63% |
| Male-to-female ratio | 2.61 | — |
| Urban origin | 65 | 85.53% |
| Self-employed/liberal profession | 32 | 42.11% |
| Retired | 16 | 21.05% |
| Self-funded care | 34 | 44.74% |
Table 1: Epidemiological and sociodemographic characteristics of thrombolysed patients
Cardiovascular risk factors were dominated by risk-associated age (71.05%), male sex (72.36%), smoking (42.11%), hypertension (38.16%), physical inactivity (26.32%) and diabetes (21.05%). The mean number of cumulative cardiovascular risk factors was four, and 85.53% of patients had at least two cardiovascular risk factors (Table 2). The mean admission delay was 5.43 hours after symptom onset, with a range from 1 hour 15 minutes to 12 hours. Forty-seven patients (61.84%) were referred from another healthcare facility, while 29 (38.15%) presented directly to the emergency department.
| Variable | Number / value | Percentage / detail |
| Risk age | 54 | 71.05% |
| Male sex | 55 | 72.36% |
| Smoking | 32 | 42.11% |
| Hypertension | 29 | 38.16% |
| Physical inactivity | 20 | 26.32% |
| Diabetes | 16 | 21.05% |
| ≥2 cardiovascular risk factors | 65 | 85.53% |
| Typical anginal pain | 66 | 86.84% |
| Mean admission delay | 5.43 h | 1 h 15 min–12 h |
| Referred patients | 47 | 61.84% |
| Subepicardial injury on ECG | 70 | 92.11% |
| Pathological Q wave | 48 | 63.16% |
| Reciprocal changes | 50 | 65.79% |
| Rhythm disorders | 17 | 22.36% |
| Conduction disorders | 20 | 26.31% |
Table 2: Cardiovascular risk factors and clinical/paraclinical presentation
Typical anginal pain was reported in 66 patients (86.84%). Mean systolic blood pressure was 141.23±29.01 mmHg and mean heart rate was 83.32±15.40 beats per minute. On admission electrocardiography, subepicardial injury was noted in 70 patients, while six had recent left bundle branch block. Pathological Q waves were found in 63.16% of cases and reciprocal changes in 65.79%. Rhythm disorders were present in 22.36% of patients and conduction disorders in 26.31%.
Doppler echocardiography, performed in 69 patients, showed segmental wall motion abnormalities in 86.96% of cases. Mean left ventricular ejection fraction was 49.58%, with severe impairment in 13.23%. Deferred coronary angiography, performed in 18 patients, mainly showed involvement of the left anterior descending artery.
All patients received loading doses of aspirin, clopidogrel and a statin. No patient underwent prehospital thrombolysis or primary angioplasty. Streptokinase was used in all patients at a dose of 1.5 million units. The mean thrombolysis delay was 6.03 hours. Thrombolysis was successful in 30 patients (39.47%) and failed in 46 (60.53%). Haemorrhagic complications occurred in nine patients (11.84%), with no haemorrhagic stroke (Figure 3). In-hospital mortality was 5.26%. Prognostic factors significantly associated with mortality were Killip class IV (p=0.027), heart rate >100 beats/min (p=0.019) and fasting blood glucose >3 g/L (p=0.039) (Table 3).
Figure 3: Main in-hospital outcomes and complications
| Variable | Number / value | Percentage / detail |
| Prehospital thrombolysis | 0 | 0% |
| Primary angioplasty | 0 | 0% |
| Streptokinase | 76 | 100% |
| Dose used | 1.5 million IU | 30–60 min infusion |
| Mean thrombolysis delay | 6.03 h | 1 h 45 min–12 h |
| Successful thrombolysis | 30 | 39.47% |
| Failed thrombolysis | 46 | 60.53% |
| Failure when thrombolysed between 6 and 12 h | 32/38 | 84.21% |
| Bleeding complications | 9 | 11.84% |
| Haemorrhagic stroke | 0 | 0% |
| Severe allergic reaction | 1 | 1.31% |
| In-hospital mortality | 4 | 5.26% |
| Mortality prognostic factors | — | Killip IV (p=0.027); HR>100/min (p=0.019); fasting glucose >3 g/L (p=0.039) |
Table 3: Thrombolysis modalities, outcomes and prognostic factors
This study shows that STEMI represented an important cause of cardiology hospitalisation at Grand-Yoff General Hospital, with a hospital prevalence of 9.49%. Among patients admitted for STEMI, nearly seven out of ten received thrombolysis. This finding highlights the central role of fibrinolysis in our setting, where primary angioplasty was not available as an emergency procedure. Although primary angioplasty is the reference reperfusion strategy when it can be performed within the recommended timeframes, thrombolysis remains an essential alternative in healthcare systems where access to cardiac catheterisation is limited [1–6].
The mean age of approximately 58 years and the male predominance observed in our series are comparable to findings usually reported in African and international STEMI series [7–10]. This male predominance may be explained by a higher frequency of smoking and other cardiovascular risk factors among men, but also by differences in exposure, healthcare-seeking behaviour and symptom recognition. The high burden of cardiovascular risk factors, with a mean of four risk factors per patient and more than 85% of patients having at least two risk factors, confirms the importance of primary prevention and early screening for modifiable risk factors [11–14].
The main finding of this study concerns delayed management. The mean admission delay was 5.43 hours and the mean thrombolysis delay was 6.03 hours. These delays are long compared with guideline recommendations, which emphasise reperfusion as early as possible, ideally within the first hours after symptom onset [1–6]. The effectiveness of fibrinolysis decreases rapidly over time, which probably explains the high failure rate observed in our series. Indeed, 50% of patients were thrombolysed between the sixth and twelfth hour, with failure in 84.21% of cases (Figure 2). This result illustrates the need to reduce both prehospital and in-hospital delays [15–18].
Figure 2: Distribution of patients according to thrombolysis delay (n=76)
The exclusive use of streptokinase probably reflects constraints related to availability and cost. Streptokinase has demonstrated its effectiveness in historical trials, but fibrin-specific agents such as alteplase, reteplase and tenecteplase are associated with higher reperfusion rates and simpler administration [19–23]. However, their cost limits their widespread use in many resource-limited countries. The absence of prehospital thrombolysis and primary angioplasty also highlights the insufficient development of structured STEMI care pathways.
Complications were dominated by heart failure, acute kidney injury, rhythm disorders, conduction disorders and haemorrhagic events. In-hospital mortality was relatively moderate at 5.26%, but unfavourable outcome concerned more than half of the patients. Killip class IV, tachycardia and severe hyperglycaemia were significantly associated with mortality, in line with classical prognostic factors in acute myocardial infarction [24–30]. These findings support the implementation of a structured STEMI pathway integrating community awareness, medicalised transport, early electrocardiography, rapid thrombolysis, tele-expertise and a pharmaco-invasive strategy.
STEMI was a frequent cardiovascular emergency in the Cardiology Department of Grand-Yoff General Hospital, Dakar. In this retrospective series of 76 thrombolysed patients, the population was predominantly male, relatively young, and characterised by a high burden of cardiovascular risk factors, mainly risk-associated age, male sex, smoking, hypertension, physical inactivity and diabetes.
Thrombolysis played a central role in the reperfusion strategy, in the absence of emergency primary angioplasty. However, admission and thrombolysis delays were long, with a mean thrombolysis delay exceeding six hours. This was associated with a high failure rate, despite the systematic use of streptokinase. Complications were dominated by heart failure, acute kidney injury, rhythm disorders, conduction disorders and haemorrhagic events. In-hospital mortality was 5.26%, with Killip class IV, heart rate above 100 beats/min and fasting blood glucose above 3 g/L identified as significant prognostic factors.
These findings highlight the need to reduce delays in seeking care, improve access to coronary reperfusion and develop a pharmaco-invasive strategy adapted to the Senegalese context
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Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.
To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina
My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.
We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.
Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.
I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.
"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".
To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.
I would like to express my sincere gratitude for the support and efficiency provided by the editorial office throughout the publication process of my article, “Delayed Vulvar Metastases from Rectal Carcinoma: A Case Report.” I greatly appreciate the assistance and guidance I received from your team, which made the entire process smooth and efficient. The peer review process was thorough and constructive, contributing to the overall quality of the final article. I am very grateful for the high level of professionalism and commitment shown by the editorial staff, and I look forward to maintaining a long-term collaboration with the International Journal of Clinical Case Reports and Reviews.
Dear Agrippa Hilda- Editorial Coordinator of Journal of Neuroscience and Neurological Surgery, "The peer review process was very quick and of high quality, which can also be seen in the articles in the journal. The collaboration with the editorial office was very good."
I would like to offer my testimony in the support. I have received through the peer review process and support the editorial office where they are to support young authors like me, encourage them to publish their work in your esteemed journals, and globalize and share knowledge globally. I really appreciate your journal, peer review, and editorial office.
My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.
My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.
My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.
The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.
Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.
Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.
I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.
I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.
I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.
We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.
I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.
"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".
I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!
Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.
Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.
International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.
Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.
As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.
Dear Hao Jiang, to Journal of Nutrition and Food Processing We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.
This is an acknowledgment for peer reviewers, editorial board of Journal of Clinical Research and Reports. They show a lot of consideration for us as publishers for our research article “Evaluation of the different factors associated with side effects of COVID-19 vaccination on medical students, Mutah university, Al-Karak, Jordan”, in a very professional and easy way. This journal is one of outstanding medical journal.
Dr. Bernard Terkimbi Utoo, I am happy to publish my scientific work in Journal of Women Health Care and Issues (JWHCI). The manuscript submission was seamless and peer review process was top notch. I was amazed that 4 reviewers worked on the manuscript which made it a highly technical, standard and excellent quality paper. I appreciate the format and consideration for the APC as well as the speed of publication. It is my pleasure to continue with this scientific relationship with the esteem JWHCI.
Testimony of Journal of Clinical Otorhinolaryngology: work with your Reviews has been a educational and constructive experience. The editorial office were very helpful and supportive. It was a pleasure to contribute to your Journal.
Thank you most sincerely, with regard to the support you have given in relation to the reviewing process and the processing of my article entitled "Large Cell Neuroendocrine Carcinoma of The Prostate Gland: A Review and Update" for publication in your esteemed Journal, Journal of Cancer Research and Cellular Therapeutics". The editorial team has been very supportive.
Dr. Katarzyna Byczkowska My testimonial covering: "The peer review process is quick and effective. The support from the editorial office is very professional and friendly. Quality of the Clinical Cardiology and Cardiovascular Interventions is scientific and publishes ground-breaking research on cardiology that is useful for other professionals in the field.
Journal of Neuroscience and Neurological Surgery. I had the experience of publishing a research article recently. The whole process was simple from submission to publication. The reviewers made specific and valuable recommendations and corrections that improved the quality of my publication. I strongly recommend this Journal.
The peer-review process which consisted high quality queries on the paper. I did answer six reviewers’ questions and comments before the paper was accepted. The support from the editorial office is excellent.
We would like to thank the Journal of Thoracic Disease and Cardiothoracic Surgery because of the services they provided us for our articles. The peer-review process was done in a very excellent time manner, and the opinions of the reviewers helped us to improve our manuscript further. The editorial office had an outstanding correspondence with us and guided us in many ways. During a hard time of the pandemic that is affecting every one of us tremendously, the editorial office helped us make everything easier for publishing scientific work. Hope for a more scientific relationship with your Journal.
Journal of Clinical Research and Reports I would be very delighted to submit my testimonial regarding the reviewer board and the editorial office. The reviewer board were accurate and helpful regarding any modifications for my manuscript. And the editorial office were very helpful and supportive in contacting and monitoring with any update and offering help. It was my pleasure to contribute with your promising Journal and I am looking forward for more collaboration.
Journal of Women Health Care and Issues By the present mail, I want to say thank to you and tour colleagues for facilitating my published article. Specially thank you for the peer review process, support from the editorial office. I appreciate positively the quality of your journal.
Journal of Clinical Cardiology and Cardiovascular Intervention The submission and review process was adequate. However I think that the publication total value should have been enlightened in early fases. Thank you for all.
Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. Auctoresonline publishing platform can be used to facilitate of optimal client-based services and should be added to health care professionals' repertoire of evidence-based health care resources.
