AUCTORES
Globalize your Research
Chat with us
Case report | DOI: https://doi.org/10.31579/2693-4779/039
*Corresponding Author: Janos Vincze, Health Human International Environment Foundation, Budapest, Hungary
Citation: J Vincze, G Vincze-Tiszay. (2021) The Sleep Modeling in the Human Organism. Clinical Research and Clinical Trials. 3(4); DOI: 10.31579/2693-4779/039
Copyright: © 2021 Janos Vincze. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 19 April 2021 | Accepted: 07 May 2021 | Published: 10 May 2021
Keywords: sleep; biophysical modeling; EEG; hypnopedia
There are three alternating states of vigilance throughout our lives: wakefulness, NREM, and REM sleep. We usually yawn before falling asleep. Yawning is an ancient reaction, an instinctive action, manifested in a person by drowsiness or boredom. Yawning is often associated with the need for stretching. Yawning is a less strong territorial reflex. During deep sleep muscular tone is sharply reduced. Relaxation of the muscles and the lowering of their tone, howeever, are not constant and necessary components of sleep. Analysis of EEG recordings soon revealed that sleep is by no means a uniform process, but can be divided into at least two sharply separated states: one is characterized by slow waves in the EEG that are completely separate from the activity of wakefulness: this so-called slow wave sleep; the other is the so-called paradoxical sleep. Hypnopedia, as a discipline, deals with the input of fixed information introduced during the period of natural sleep, also known as sleep learning. Our hypnopedia researches was a pleasant surprise, because they were able to reproduce texts they did not know with an efficiency of approx. 25%.
Every science has central issues, such a key problem for biophysics is modeling. The phenomena that take place in the world around us are usually very complex. In living systems, many parameters are present at the same time in almost every process, and they are intricately interdependent. There are hardly any cases where we can expect only a few and such simply interrelated parameters in relation to which we can use simple models in their examination and description. At first, we often think that the difficulty comes from the large number of parameters, but later we realize that we need to look deeper for the cause, namely in the nonlinear context of each parameter.
Therefore, we select the most characteristic parameters of the processes and create a construction in which the processes can be implemented through the processes with an adequate approach. A subset of our existing knowledge and assumptions, as well as the subset to be examined selected from the set of experiments performed (there may be thought experiments!) and the results of the examinations are called models.
Thus, the model cannot be identified with the system under examination, but it facilitates a more complete understanding of it. Modeling, in its simplest form, is a sharp, polarized question about the phenomenon in question. The model is in a similarity relation to the modeled system. A model is a theoretically or materially realized system that, by reflecting or reproducing an object of research, is able to temporarily replace it. The model can always be interpreted only in conjunction with the modeling.
Two systems (A and B) are considered to be models (or modeled) relative to each other if it is possible to homomorphically map system A to system A’ and system B to system B’ so that A’ and B’ are isomorphic to each other. Thus, the model is a simplified, comprehensible, practically implemented or theoretically imagined, proportionally reduced or enlarged, most of the time accurately describable in terms of mathematics, idealized copy of the system examined, which more or less correctly illustrates the peculiarities of the system or process examined.
When creating a model, one must be aware that the model is not the same as the system under study and does not fully reflect all its properties. Nevertheless, the correctly formed model bears the most important criteria of the examined system and is thus suitable for the exploration of the decisive regularities.
A lucky model describes the knowledge of a given moment, but in addition it allows assumptions, and these can be translated into the language of reality and model specific situations. A well-chosen model helps not only to raise the issue, but also to study the phenomena scientifically. Biophysics cannot lack models, but it needs to correspond to actual reality. Not everything can be modeled.
The significant time spent sleeping also indicates that it is a matter of meeting some important biological need, as evidenced by the fact that if we prevent sleep for days, the body then makes up for the omission, and even completes paradoxes with particular precision. The evolution of the
During deep sleep muscular tone is sharply reduced. Most muscles in a sleeping person are completely relaxed, which is why objects fall from the hands of a person sleeping in a sitting position and why his head sinks onto his chest, and his trunk sags.
Relaxation of the muscles and the lowering of their tone, howeever, are not constant and necessary components of sleep. Even during normal sleep various movements are possible, and a definite pose can be maintained for a long time, as when sleeping in a sitting posture. All the senses, i.e. vision, hearing, taste, smell, and the tactile sense are greatly reduced, and a much stronger stimulus is required to induce a reaction in a sleeping person than when he is awake.
The reflex function is sharply reduced during sleep. Conditioned reflexes are inhibited, unconditioned ones are considerably weakened. Their thresholds of stimulation are considerably raised, and the latent period lengthened. Sensomotor changes dominate the picture of sleep as compared with changes in vegetative functions.
The significant time spent sleeping also indicates that it is a matter of meeting some important biological need, as evidenced by the fact that if we prevent sleep for days, the body then makes up for the omission, and even completes paradoxes with particular precision.
Common sense dictates that sleep is simply perceived as rest, regeneration. However, it is easy to see that the body does not need sleep to rest. Is it about resting the brain? However, the regeneration of nerve cells is a very quick process, it is believed that the neurons controlling the heartbeat or breathing rest during the interval between two consecutive breaths or heartbeats.
The possibility of objective experimental studies regarding sleep was provided only by the development of technology in the 1950s. This was mainly due to the widespread use of electroencephalographic examinations. An electroencephalogram (EEG) is a graphical representation of the electrical activity of brain neurons; a measurement signal on the order of microvolts that shows the change in activity of thousands of neurons over time. The EEG is registered with low-resistance electrodes placed on the scalp.
EEG diversion is performed using low-resistance electrodes placed on the scalp. Depending on the equipment, diversion can take place on more than 200 channels with a defined measurement interval. The principle of measurement is as follows: we measure the potential difference between two electrodes. Bipolar conduction between active electrodes (below which there are active neurons) or monopolar conduction between inactive (reference) electrodes. The derived signal is amplified and then filtered according to the frequency range to be examined. The result obtained can be used to perform various analyzes on the given signals with the help of computers – quantitatively by fast Fourier analysis.
Electrodes placed on the scalp do not conduct the action potential, but synaptic potentials because the synaptic voltage is lower (in the order of microvolts) than the action potential (1–2 mV). The action potential is measured with microelectrodes due to its speed, while the synaptic potential can be measured with a cap placed on the scalp. AP has a nature of all or nothing, while in the case of synaptic potentials, their mathematical sum is derived in the form of EEG, i.e. the sum of voltage fluctuations.
Analysis of EEG recordings soon revealed that sleep is by no means a uniform process, but can be divided into at least two sharply separated states: one is characterized by slow waves in the EEG that are completely separate from the activity of wakefulness: this so-called slow wave sleep; the other is the so-called paradoxical sleep, in which wake-like activity is seen on the EEG, although the individual’s sleep is deepest at this time – hence the contradictory paradoxical marker (REM - Rapid Eye Movement).
Slow-wave sleep, as its name implies, is caused by slow waves occurring in increasing numbers and at lower and lower frequencies in the EEG, as well as periods of 2–3 seconds consisting of more frequent waves, being characterized by the so-called “sleep spindles”. Based on the electrical activity of the brain, several stages of slow-wave sleep can be distinguished, e.g. four sleep states are usually defined from EEG curves, denoted by numbers 1–4 from superficial sleep to deep sleep. Although the different origins of each stage arise from time to time, slow-wave sleep is mostly considered qualitatively one, with each stage denoting different sleep depths.
Characteristics of each phase:
Under normal conditions, electrical activity in the brain follows the development of sleep well. Sleep progresses from stage 1, i.e., from the most superficial stage, to stage 4, then its depth decreases again, and – before another stage 1 occurs – paradoxical sleep appears. Sleep is deepest in the first half of the night, especially in the first sleep cycle. In later cycles, the amount of stage 4 is less and less, towards the morning the slow-wave sleep does not even go beyond stage 2.
Paradoxical sleep is a qualitatively different state from slow-wave sleep. Cerebral electrical activity is characterized by vigorous, rapid activity, which can sometimes exceed wakefulness activity. The muscles relax completely. Sometimes, however, stormy movements occur, but they are always limited to a specific group of muscles: the wrist moves, one finger bends, and so on. Occasionally, high-amplitude eye movements are very common and are often accompanied by blood filling of the genitals, resulting in erection of the penis or clitoris in women. The heartbeat suddenly increases and then decreases, blood pressure fluctuates sharply, breathing may become irregular, and even temporary complete respiratory arrest may occur. Respiratory arrest in infants can sometimes be fatal. During paradoxical sleep, the thermoregulation is switched off, but since the length of each paradoxical phase is 6–15 minutes, no significant cooling can occur on the covered person. The amount of paradoxical sleep is highest in newborns, reaching up to 70% of total sleep time. This drops to about 20% in adulthood.
Hypnopedia, as a discipline, deals with the input of fixed information introduced during the period of natural sleep, also known as sleep learning. In the different phases of sleep, the perception of stimuli is preserved. For example, a story, a tale, whispered in the ear of a sleeping person, becomes “familiar” after awakening, without being able to tell its content, or when and from whom, where it was heard.
In the early 1960s, we set up a sleep laboratory at the Institute of Biophysics, University of Medicine. Compared to the circumstances at the time, it could be said to be modern: EEG, EMG, portable ECG, tape recorders, oscilloscopes and much more that we would have needed, in addition to these, were put together by us. There were plenty of experimental subjects because it was natural for medical students to perform various human experiments on volunteers.
I applied first to have a “test drive” done by my colleagues. They taught me a text while sleeping that I had no idea about. After multiple team discussions we have decided to register as many parameters during sleep as possible. This is how we realized that when eye movement displays the REM phase, the subjects do not learn, as the sleeping organism wakes up easily, and if this occurs several times within a given period, they would feel very tired during the daytime. A similar interpretation was given to the importance of breathing, the alternation of the EEG waveforms and the warning signs of muscle movement.
After several months of experimentation, we signed up with eight medical students for the institutional meeting. Colleagues working in the institute received the full text of a poem, along with the author’s name. The head of the institute asked whether the medical students knew the poems, whether they heard them or not, and then he read the first verse. All eight students said that they were not familiar with the poem. Then we started the recording from the second verse that they learned during sleep. The students were able to recite the poem with an efficiency of approx. 75%. It was an incredible and spectacular success and evidence available for everyone regarding learning during sleep. The result: the laboratory was shut down by the military.
Now, at an old age, I repeated the experiment again under special family circumstances, without any means. I spent more time with my kids and agreed with them to repeat my hypnopedia experiments on my grandchildren. On several occasions, I performed the following experiment on 10 of my grandchildren — between 6 and 10 years old. After they fell asleep I went into their room and repeated a story I had written 10 times for an hour for 7 days. So my grandchildren, while sleeping, heard the same text 70 times as I read it. We later checked to see if they could repeat or recall anything from the text – completely unknown to them – that was read to them at night. The result was a pleasant surprise, because they were able to reproduce texts they did not know with an efficiency of approx. 25%.
We assume that during hypnopedia we want to convey certain information to the given person and later we want to check its recording, that is, we have to ask back, so it can be considered a dialogue.
Therefore, it is worth writing the information matrix before starting hypnopedia, because with the help of this we break down the information itself into very small parts and in this way the essential and less important parts of the information duration become more and more obvious to the experimenter.
Let our information matrix be:
During the experiment, the information was repeated m times. The question immediately arises: how many times should it be repeated in a single experiment? We found that the information return efficiency (hd) is maximal when in an experiment the number of repetitions is of approx. 5-7 times (m1).
Efficacy could be increased if the experiment was repeated during several consecutive sleeps:
m1 + m2 + … + m5 ≈ 35
Thus, maximum efficiency (hd*) is reached when we repeated the information we wanted to enter about 35 times on 5 occassions:
We analyzed certain elements of the Bkd information matrix according to the importance and severity of the information. In the acquisition of wakefulness information, the subjects selectively memorized the same information, i.e. transferred it to their preliminary information pyramid, compared it with their previous knowledge, and then recorded it. In the case of recording during sleep, there is a lack of comparison, and therefore the essential and much less important parts are recorded with the same efficiency by human memory, the maximum efficiency of reproduction is usually between 25 and 30 percent.
The learning technique of sleep learning is limited to repetitions, thus consolidating those learned because the learning of new knowledge takes place in an alert state. This does not preclude the recording of new information during sleep learning, which is recommended in such cases e.g. learning foreign words, geographical names, historical dates, so simple memorizable data.
Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. Auctoresonline publishing platform can be used to facilitate of optimal client-based services and should be added to health care professionals' repertoire of evidence-based health care resources.
Journal of Clinical Cardiology and Cardiovascular Intervention The submission and review process was adequate. However I think that the publication total value should have been enlightened in early fases. Thank you for all.
Journal of Women Health Care and Issues By the present mail, I want to say thank to you and tour colleagues for facilitating my published article. Specially thank you for the peer review process, support from the editorial office. I appreciate positively the quality of your journal.
Journal of Clinical Research and Reports I would be very delighted to submit my testimonial regarding the reviewer board and the editorial office. The reviewer board were accurate and helpful regarding any modifications for my manuscript. And the editorial office were very helpful and supportive in contacting and monitoring with any update and offering help. It was my pleasure to contribute with your promising Journal and I am looking forward for more collaboration.
We would like to thank the Journal of Thoracic Disease and Cardiothoracic Surgery because of the services they provided us for our articles. The peer-review process was done in a very excellent time manner, and the opinions of the reviewers helped us to improve our manuscript further. The editorial office had an outstanding correspondence with us and guided us in many ways. During a hard time of the pandemic that is affecting every one of us tremendously, the editorial office helped us make everything easier for publishing scientific work. Hope for a more scientific relationship with your Journal.
The peer-review process which consisted high quality queries on the paper. I did answer six reviewers’ questions and comments before the paper was accepted. The support from the editorial office is excellent.
Journal of Neuroscience and Neurological Surgery. I had the experience of publishing a research article recently. The whole process was simple from submission to publication. The reviewers made specific and valuable recommendations and corrections that improved the quality of my publication. I strongly recommend this Journal.
Dr. Katarzyna Byczkowska My testimonial covering: "The peer review process is quick and effective. The support from the editorial office is very professional and friendly. Quality of the Clinical Cardiology and Cardiovascular Interventions is scientific and publishes ground-breaking research on cardiology that is useful for other professionals in the field.
Thank you most sincerely, with regard to the support you have given in relation to the reviewing process and the processing of my article entitled "Large Cell Neuroendocrine Carcinoma of The Prostate Gland: A Review and Update" for publication in your esteemed Journal, Journal of Cancer Research and Cellular Therapeutics". The editorial team has been very supportive.
Testimony of Journal of Clinical Otorhinolaryngology: work with your Reviews has been a educational and constructive experience. The editorial office were very helpful and supportive. It was a pleasure to contribute to your Journal.
Dr. Bernard Terkimbi Utoo, I am happy to publish my scientific work in Journal of Women Health Care and Issues (JWHCI). The manuscript submission was seamless and peer review process was top notch. I was amazed that 4 reviewers worked on the manuscript which made it a highly technical, standard and excellent quality paper. I appreciate the format and consideration for the APC as well as the speed of publication. It is my pleasure to continue with this scientific relationship with the esteem JWHCI.
This is an acknowledgment for peer reviewers, editorial board of Journal of Clinical Research and Reports. They show a lot of consideration for us as publishers for our research article “Evaluation of the different factors associated with side effects of COVID-19 vaccination on medical students, Mutah university, Al-Karak, Jordan”, in a very professional and easy way. This journal is one of outstanding medical journal.
Dear Hao Jiang, to Journal of Nutrition and Food Processing We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.
As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.
Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.
International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.
Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.
Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.
I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!
"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".
I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.
We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.
I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.
I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.
I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.
Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.
“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.
Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.
The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.
Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
