The Prevalence, Symptoms, Risk Factors, Awareness, and Health-Seeking Behaviours Related to Pelvic Inflammatory Disease (Pid) Among Women of Reproductive and Perimenopausal age in Delta State

Research Article | DOI: https://doi.org/10.31579/2578-8965/308

The Prevalence, Symptoms, Risk Factors, Awareness, and Health-Seeking Behaviours Related to Pelvic Inflammatory Disease (Pid) Among Women of Reproductive and Perimenopausal age in Delta State

  • Ogbutor Udoji Godsday 1*
  • Uvietessivwi Oghenenyoren Gloria 1
  • Ogbutor Emeke Godson 1
  • Anastacia Ojimba 2
  • Nwose Jephtah 2
  • Chukwuemeka Ephraim 2
  • Ezunu Esther 3
  • Bernard Elo-Oghene Christiana 3

1Faculty of Basic Medical Sciences, Delta State University Abraka, Delta State, Nigeria.

2Department of Internal Medicine, Federal Medical Centre Asaba, Delta State, Nigeria.

3Department of Nursing Services, Federal Medical Centre Asaba, Delta State, Nigeria.

*Corresponding Author: Ogbutor Udoji Godsday., Faculty of Basic Medical Sciences, Delta State University Abraka, Delta State, Nigeria.

Citation: Ogbutor Udoji Godsday, Uvietessivwi Oghenenyoren Gloria, Ogbutor Emeke Godson, Anastacia Ojimba, Nwose Jephtah., et al, (2026), The Prevalence, Symptoms, Risk Factors, Awareness, and Health-Seeking Behaviours Related to Pelvic Inflammatory Disease (Pid) Among Women of Reproductive and Perimenopausal age in Delta State, J. Obstetrics Gynecology and Reproductive Sciences, 10(4) DOI:10.31579/2578-8965/308

Copyright: © 2026, Ogbutor Udoji Godsday. This is an open-access article distributed under the terms of The Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Received: 15 April 2026 | Accepted: 30 April 2026 | Published: 14 May 2026

Keywords: prevalence, pelvic inflammatory disease, reproductive women, perimenopause women

Abstract

Background: Pelvic inflammatory disease (PID) has traditionally been associated with younger women of reproductive age, with limited attention given to perimenopausal women. Aim: This study assessed the prevalence, risk factors, awareness, and health-seeking behaviours related to PID among reproductive and perimenopausal women in Delta State, Nigeria. 

Methodology: A descriptive cross-sectional survey was conducted among 400 women aged 20–55 years recruited from healthcare centres, markets, religious institutions, and community gatherings using multistage sampling. Data were collected using a structured questionnaire and analysed using descriptive and inferential statistics. 

Results: The overall prevalence of PID was 60%, with significantly higher prevalence among perimenopausal women (75%) compared with reproductive-aged women (45%) (Z = –6.12, p < 0.001). Symptoms significantly associated with PID included irregular menstruation (t = 16.31), dyspareunia (t = 14.82), pelvic pain (t = 15.10), frequent urination (t = 11.22), and difficulty conceiving (t = 13.40) (p < 0.001). Major risk factors included previous sexually transmitted infections, intrauterine device use, multiple sexual partners, history of abortion, and pelvic surgery (p < 0.01). Women in polygamous marriages showed nearly threefold higher odds of PID (OR = 2.95, p < 0.001). 

Conclusion: These findings highlight the influence of clinical, behavioural, and socio-cultural factors on PID prevalence and emphasizes the need for targeted public health interventions.

1.Introduction

Pelvic inflammatory disease (PID) is a major public health and gynaecological condition characterized by inflammation of the upper female reproductive tract, including the endometrium, fallopian tubes, and peritoneum [1, 2]. Although traditionally associated with younger women, emerging evidence indicates that PID also affects perimenopausal women, who remain underrepresented in research and health policy despite biological and behavioural changes that may increase susceptibility to genital tract infections [3, 4, 5]. Women’s health during midlife is influenced by physiological, sociocultural, and environmental factors, highlighting the need for integration of sexual and reproductive health services into menopausal care, particularly in low-resource settings [6, 7]. 

PID has a multifactorial aetiology, most commonly involving Chlamydia trachomatis and Neisseria gonorrhoea, although polymicrobial infections associated with bacterial vaginosis and Mycoplasma genitalium are increasingly recognized [8, 9, 10, 11]. Untreated infections can result in infertility, chronic pelvic pain, ectopic pregnancy, and increased risk of ovarian malignancy [12,13]. Reproductive tract infections remain major contributors to female morbidity globally, with sub-Saharan Africa disproportionately affected due to limited STI prevention, screening, and healthcare access [14, 15, 16]. Risk factors for PID include multiple sexual partners, unprotected intercourse, previous STIs, unsafe abortion, and postpartum infections [17,18]. Perimenopausal women experience additional biological vulnerabilities due to declining oestrogen levels, reduced vaginal mucosal immunity, and age-related immune changes that increase susceptibility to infection [19, 20, 21]. Psychosocial factors such as marital instability, economic vulnerability, and misconceptions regarding STI risk during midlife further contribute to exposure [22, 23, 24]. Cultural stigma surrounding sexual activity among older women may delay healthcare seeking and complicate diagnosis, particularly as symptoms may be nonspecific [25, 26, 27, 28].

Untreated or recurrent PID can lead to infertility, chronic pelvic pain, sexual dysfunction, psychological distress, and increased healthcare costs [29, 30, 31, 32, 33]. In Nigeria, limited research focusing on perimenopausal women contributes to low clinical suspicion and under-treatment [34, 35]. Therefore, this study assessed the prevalence, risk factors, awareness, and health-seeking behaviors related to PID among reproductive and perimenopausal women in Delta State, Nigeria.              

2. Materials and Methods

2.1 Research Design

This study employed a descriptive cross-sectional survey design to assess the prevalence, awareness, risk factors, and health-seeking behaviours related to pelvic inflammatory disease (PID) among reproductive and perimenopausal women. The choice of a descriptive cross-sectional survey design is based on its suitability for capturing information at a single point in time, making it ideal for studying prevalence, knowledge, awareness, and experiences related to PID among the target population.

2.2 Study Area

The study was conducted in Delta State, Nigeria. Delta State, located in the South-South geopolitical zone of Nigeria, has a diverse population with varying socio-economic backgrounds, making it an ideal location. Six Local Government Areas (LGAs) representing urban, semi-urban, and rural populations were selected which are Oshimili South, Ethiope East, Ughelli North, Warri South, Ndokwa West, and Patani LGAs. These LGAs were selected to ensure geographical diversity, socio-economic representation, and variation in healthcare access, all of which are essential in assessing PID prevalence and its impact on reproductive and perimenopause women in Delta State

2.3 Study Population

The study population comprised women aged 20–55 years residing in the selected LGAs of Delta State. This age range is chosen to ensure adequate representation, as PID affects women of reproductive age, including perimenopause women who are the primary focus of this study.

2.4 Sample Size Determination

 For this study, the minimum number of sample required is computed in accordance with Cochran’s formula for sample size estimation: 

Where: 

= required sample size 

Z = standard normal deviation (1.96 for a 95% confidence level) 

p = Based on previous studies, let’s assume a conservative estimate of 50% (0.5) since it's the most statistically conservative and gives the maximum sample size.

q = 1 - p (0.80) 

e = margin of error (5% or 0.05) 

d = precision or margin of error (± 4.9% or 0.049).

Substituting the values: 

Thus, the final sample size is 400 respondents were selected to ensure adequate representation and statistical validity.

2.5 Sampling Technique

A multistage sampling technique was used to ensure a diverse and representative selection of respondents:

Stratified Sampling: Delta State was divided into senatorial districts, and four LGAs were selected to represent different geographical and socio-economic backgrounds.

Cluster Sampling: Each LGA was further divided into clusters (healthcare centers, markets, religious institutions, and community areas).

Systematic Random Sampling: Women within the selected clusters were randomly chosen using a sampling interval to ensure fairness.

Purposive Sampling: In healthcare centers, women diagnosed or treated for reproductive health issues were specifically targeted for inclusion.

This approach ensured representativeness, reduced bias, and enhanced the generalizability of the study findings. 

2.6 Data Collection Procedure

Data were collected using a structured questionnaire administered by the principal researcher and trained research assistants across selected community and healthcare settings. Participants were informed about the study objectives and confidentiality was assured. Informed consent was obtained before questionnaire administration. Each questionnaire required approximately 20–30 minutes to complete, and completed questionnaires were screened for completeness prior to analysis.

2.7 Instrument for Data Collection

Data were collected using a structured questionnaire consisting of six sections and 34 items aligned with the study objectives. The sections assessed socio-demographic characteristics, PID prevalence, symptom patterns, reproductive and STI history, awareness of PID, and health-seeking behaviours. The instrument was reviewed by public health and gynaecology experts and pilot-tested for clarity and relevance.

2.8 Validity of the Instrument

Instrument validity was ensured through expert review and pilot testing. Content validity was established by specialists in public health and gynaecology. Face validity was assessed through pilot testing among women similar to the target population. Construct validity was achieved by aligning questionnaire items with established theoretical and empirical literature on PID.

2.9 Reliability of the Instrument

Reliability was assessed through a pilot study involving 30 participants who were excluded from the main study. Internal consistency of questionnaire sections was evaluated using Cronbach’s alpha, with values of 0.7 or higher considered acceptable.

2.10 Method of Data Analysis

Data were analyzed using Statistical Package for Social Sciences (SPSS) version 26. Descriptive statistics including frequencies, percentages, means, and standard deviations were used to summarize respondent characteristics and study variables. Inferential analysis was performed using Chi-square tests to examine associations between PID occurrence and selected risk factors. Statistical significance was set at p < 0>

2.11 Inclusion and Exclusion Criteria

2.11.1 Inclusion Criteria

Women aged 20–55 years who were residents of the selected LGAs, capable of completing the questionnaire, and who provided informed consent were included.

2.11.2 Exclusion Criteria

Women who had undergone hysterectomy or salpingectomy, those who had reached menopause, those with unrelated chronic gynaecological conditions, or those unwilling or unable to participate were excluded.

2.12 Ethical Considerations

Ethical approval was obtained from the Institutional Research Ethics Committee of the Faculty of Basic Medical Sciences, Delta State University, Abraka (RBC/FBMC/DELSU/25/756). Participation was voluntary, and confidentiality of participant information was maintained.

3. Results

3.1 Demographic Data of Respondents 

The demographic characteristics of the 400 participants presents a broad view of the population involved in the study. These include age, marital status, educational background, occupation, number of children, religion, menstrual status, and prior gynaecological history. The diversity in these variables enriches the analysis of PID in terms of exposure, awareness, and experiences. The age distribution is balanced, with the highest representation (25%) in the 45–49 group. This reflects a strong perimenopause presence. The even spread supports unbiased, age-based comparisons. Most respondents are in monogamous marriages (45%), followed by singles (20%) and polygamous (15%). Divorced/separated and widowed women (10?ch). This range supports insights into PID risks and health-seeking behaviour. Secondary education holders (40%) dominate, followed by tertiary (25%) and primary (20%). Only 10% had no formal education, while 5% had postgraduate degrees. The range allows analysis of education’s role in PID awareness and care. Trading (25%) and professional/civil service (20?ch) top the occupational list, while artisans and the unemployed follow (15?ch). The mix reflects varied socioeconomic backgrounds, affecting health access and PID exposure.

Most women have 3–4 children (40%), with 1–2 and 5+ children at 25?ch. Nulliparous women make up 10%. The data supports understanding how childbearing history relates to PID prevalence and complications. 

Menstrual Status: About 52.5% report irregular menstruation, while 47.5% menstruate once in a while. This split shows a blend of reproductive and post-reproductive women, enabling assessment of PID risk across menstrual health stages.

VariablesCategoriesFrequencyPercentage
Age Group (Years)20-296015.0%
 30-398020.0%
 40-448020.0%
 45-4910025.0%
 50-558020.0%
Marital StatusSingle8020.0%
 Married (Monogamous)18045.0%
 Married (Polygamous)6015.0%
 Divorced/Separated4010.0%
 Widowed4010.0%
Educational LevelNo Formal Education4010.0%
 Primary8020.0%
 Secondary16040.0%
 Tertiary10025.0%
 Postgraduate205.0%
OccupationUnemployed6015.0%
 Trader10025.0%
 Civil Servant8020.0%
 Artisan6015.0%
 Professional8020.0%
 Other205.0%
Numbers of Children0 (Nulliparous)4010.0%
 1–210025.0%
 3–416040.0%
 5+10025.0%
Menstrual StatusIrregular21052.5%
 Once in a while/absent19047.5%
Total 400100%

Table 1: Demographic Distribution of Respondents.

(Source: Computed from Author’s survey data, 2025)

3.2 Prevalence of PID

In order to assess the Prevalence of Pelvic Inflammatory Disease (PID) among reproductive and perimenopause women, participants were asked to respond to a series of statements addressing PID among reproductive and perimenopause women. The responses were measured using Yes/No. Diagnosis of PID: 60% of respondents reported having been diagnosed with PID (Mean = 1.60, SD = 0.49). This indicates a high prevalence and highlights the need for improved diagnostic access and awareness.

Persistent Pelvic Pain: 65% experienced persistent pelvic pain (Mean = 1.65, SD = 0.48), suggesting a strong link to possible undiagnosed or recurrent PID, especially among untreated individuals.

Abnormal Vaginal Discharge: Abnormal discharge was reported by 55% (Mean = 1.55, SD = 0.50), pointing to ongoing reproductive tract infections commonly associated with PID.

Hospital: Only 25% had been hospitalized (Mean = 1.25, SD = 0.43), implying that most PID cases remain non-severe or are managed outside hospital settings.

PID Treatment in the Past Two Years: 45% reported recent PID treatment (Mean = 1.45, SD = 0.50), indicating recurring infections and reinforcing the condition’s ongoing relevance. The prevalence of pelvic inflammatory disease among respondents is shown in Table 2.

StatementYes (n)No (n)% YesMeanSD
Have you ever been diagnosed with PID?24016060.0%1.600.49
Have you experienced persistent pelvic pain?26014065.0%1.650.48
Have you had abnormal vaginal discharge recently?22018055.0%1.550.50
Have you been hospitalized for reproductive infection?10030025.0%1.250.43
Have you undergone PID treatment in the past 2 years?18022045.0%1.450.50

Table 2: Prevalence of PID among Reproductive and Perimenopausal Women.

3.3 Symptoms Associated with PID 

In order to assess the Symptoms and Diagnosis of Pelvic Inflammatory Disease (PID), participants were asked to respond to a series of statements addressing symptoms of PID. The responses were measured using 4- Likert-type (Strongly Agree, Agree, Strongly Disagree, and Disagree). Irregular Menstruation: With a mean of 3.05, many relate PID to menstrual issues, supporting its diagnostic relevance.

Pain during Intercourse: Mean of 2.85 with 45.0% agreeing shows dyspareunia is prevalent and likely underreported.

Pelvic Pain: Mean of 2.90 shows that most respondents experience this common PID symptom, though with some variation (SD = 0.88).

Frequent or Painful Urination: With a mean of 2.60 (SD = 1.00), responses were more varied. 

Difficulty Conceiving: The lowest mean score (2.45, SD = 0.98) indicates moderate disagreement. The symptoms associated with pelvic inflammatory disease among respondents are presented in Table 3.

S/NStatementSA (F/%)A (F/%)D (F/%)SD (F/%)Mean ± SD
Q1I experience irregular menstruation

160

(40.0%)

140

(35.0%)

60

(15.0%)

40

(10.0%)

3.05 ± 0.91
Q2I feel pain during intercourse

100

(25.0%)

180

(45.0%)

80

(20.0%)

40

(10.0%)

2.85 ± 0.87
Q3I experience fever with pelvic pain

120

(30.0%)

160

(40.0%)

80

(20.0%)

40

(10.0%)

2.90 ± 0.88
Q4I urinate frequently or with pain

100

(25.0%)

120

(30.0%)

100

(25.0%)

80

(20.0%)

2.60 ± 1.00
Q5I have difficulty conceiving

80

(20.0%)

100

(25.0%)

140

(35.0%)

80

(20.0%)

2.45 ± 0.98

Table 3: Distribution of Respondents of Symptoms and Diagnosis of PID

(Source: Computed from Author’s survey data, 2025)

3.4 Reproductive History, STI History, and Contraceptive Use 

In order to assess the Reproductive History, STI History, and Contraceptive Use, participants were asked to respond to a series of statements addressing reproductive history. The responses were measured using Yes/No. Multiple Sexual Partners (Past 12 Months): 35% reported multiple partners (Mean = 1.35, SD = 0.48), indicating notable exposure to STIs. 

History of STIs: 40% had prior STI diagnoses (Mean = 1.40, SD = 0.49), supporting a strong link between STIs and PID. 

Use of Intrauterine Devices (IUDs): 30% reported IUD use (Mean = 1.30, SD = 0.46), warranting attention. 

History of Abortion: 45% had a history of abortion (Mean = 1.45, SD = 0.50), suggesting possible reproductive tract disruptions. Inadequate post-abortion care may increase PID risk.

History of Ectopic Pregnancy: 20% of respondents reported ectopic pregnancy (Mean = 1.20, SD = 0.40), the lowest among indicators. The distribution of respondents based on symptoms and diagnosis of PID is shown in Table 4.

SStatementYES (F/ %)NO (FS/ %)Mean ± SD
1.Multiple sexual partners (past 12 month)140 (35.0%)260 (65.0%)1.35 ± 0.48
2.History of STIs160 (40.0%)240 (60.0%)1.40 ± 0.49
3.Use of IUDs120 (30.0%)280 (70.0%)1.30 ± 0.46
4.History of abortion180 (45.0%)220 (55.0%)1.45 ± 0.50
5.History of ectopic pregnancy80 (20.0%)320 (80.0%)1.20 ± 0.40

Table 4: Distribution of Respondents by Reproductive History, STI History, and Contraceptive Use (N=400)

(Source: Computed from Author’s survey data, 2025)

In order to assess the Awareness and Knowledge of Pelvic Inflammatory Disease (PID), participants were asked to respond to a series of statements addressing awareness and knowledge of PID. The responses were measured using 4- Likert-type (Strongly Agree, Agree, Strongly Disagree, and Disagree). Awareness of PID: With a mean score of 3.40 (SD = 0.79), most respondents were aware of PID. 

3.5 Awareness and Knowledge of PID 

Knowledge of PID Symptoms: A mean of 3.30 (SD = 0.78) indicates good knowledge of key symptoms. 

Understanding of PID Complications: Respondents showed strong agreement (Mean = 3.35, SD = 0.78) that PID leads to serious outcomes. 

Knowledge of Treatment Access: A mean score of 3.30 (SD = 0.78) reflects awareness of where to access care. 

Regular check-ups: This item had the highest mean (3.50, SD = 0.71), indicating strong belief in check-ups for prevention. It reflects high preventive health literacy among the participants.

SStatementSA (F/%)A (F/%)D (F/%)SD (F/%)Mean ± SD
1I have heard about PID before

240

(60.0%)

100

(25.0%)

40

(10.0%)

20

(5.0%)

3.40 ± 0.79
2I know the symptoms of PID

200

(50.0%)

140

(35.0%)

40

(10.0%)

20

(5.0%)

3.30 ± 0.78
3PID leads to serious complications

220

(55.0%)

120

(30.0%)

40

(10.0%)

20

(5.0%)

3.35 ± 0.78
4I know where to get treatment

200

(50.0%)

140

(35.0%)

40

(10.0%)

20

(5.0%)

3.30 ± 0.78
5Regular check-ups help prevent PID

260

(65.0%)

100

(25.0%)

20

(5.0%)

20

(5.0%)

3.50 ± 0.71

Table 5: Distribution of Respondents by Awareness and Knowledge of PID (N=400)

(Source: Computed from Author’s survey data, 2025)

3.6 Health-Seeking Behaviours and Preventive Practices 

In order to assess the health-Seeking Behaviours and Preventive Practices of Pelvic Inflammatory Disease (PID), participants were asked to respond to a series of statements addressing Health behaviour. The responses were measured using 5- Likert-type (Strongly Agree, Agree, Strongly Disagree, and Disagree). Seeking Care for Symptoms: Mean of 3.20 indicates moderate proactiveness, though a quarter avoid care.

Regular Gynaecology Check-ups: Yes (mean = 3.45) shows good preventive engagement.

Completing Antibiotics: Yes mean (3.62), reflecting strong adherence to treatment, a positive trend.

Safe Sex Practices: Mean of 3.52 suggests awareness is high but with scope for education.

Discussing PID with Professionals: Mean of 3.32 shows over half engage in discussions, but many still lack direct healthcare dialogue.

 StatementPID DiagnosisNMean ± SD
1.I seek medical care when I notice pelvic symptoms.Yes1703.20 ± 1.18
  No2103.72 ± 1.27
2I go for regular gynaecological check-ups.Yes1653.45 ± 1.12
  No2184.08 ± 1.09
3.I complete prescribed antibiotics during infections.Yes1723.62 ± 1.10
  No2214.08 ± 1.12
4.I practice safe sex.Yes1743.52 ± 1.15
  No2223.96 ± 1.13
5.I’ve discussed PID with a healthcare provider.Yes1683.32 ± 1.18
  No2183.74 ± 1.17

Table 6: Health-Seeking Behaviours and Preventive Practices

(Source: Computed from Author’s survey data, 2025)

3.8 Test Of Significance

Inferential statistics were used, including Chi-square tests for associations, T-tests for comparing group means, One-Way ANOVA for differences across educational levels, and Logistic Regression to predict PID awareness and prevalence based on factors like marital status and gynaecological history. Hypothesis testing determined whether observed differences were statistically meaningful, using a 95% confidence level (α = 0.05). A p-value < 0>

In table 7, the study tested whether there is a significant difference in the prevalence of Pelvic Inflammatory Disease (PID) between reproductive and perimenopause women. With equal sample sizes of 200, the observed PID rates were 45% for reproductive women and 75% for perimenopausal women. A Z-test yielded a statistic of -6.12 and a p-value less than 0.001. Since the p-value is well below the 0.05 significance level, the null hypothesis was rejected. This indicates a statistically significant difference in PID prevalence, with perimenopause women showing a higher rate than reproductive women.

ParameterReproductive ValuePerimenopause Value
Sample size (n)200200
Observed cases with PID90150
Observed proportion (p̂)0.45 (45.0%)0.75 (75.0%)
Pooled proportion (p₀)0.60 (60.0%)0.60 (60.0%)
Significance level (α)0.050.05
Test statistic (Z)-6.12-6.12
p-value< 0.001< 0>

Table 7: Comparison of PID Prevalence between Reproductive and Perimenopause Women

(Source: Computed from Author’s survey data, 2025)

Symptomt-valuep-valueInterpretation
Irregular Menstruation 16.31< 0>Significant association with PID
Pain During Intercourse14.82< 0>Significant association with PID
Pelvic Pain15.10< 0>Significant association with PID
Frequent Urination11.22< 0>Significant association with PID
Difficulty Conceiving 13.40< 0>Significant association with PID

Table 8: Association between Reported Symptoms and PID Diagnosis

(Source: Computed from Author’s survey data, 2025)

Table 8 shows independent samples t-test results assessing the association between core PID symptoms and PID diagnosis. All five symptoms had t-values between 11.22 and 16.31, with p-values < 0.001, indicating significant differences.

Item% YesMean ScoreSDt-valuep-value
Multiple sexual partners (12 months)35.0%1.350.485.41<0.001
History of STIs40.0%1.400.496.85< 0.001
Use of IUDs30.0%1.300.463.92< 0.001
History of abortion45.0%1.450.507.89<0.001
History of ectopic pregnancy20.0%1.200.402.750.006

Table 9: Risk Factor Association

 (Source: Computed from Author’s survey data, 2025)

Table 10 presents t-test results on five PID risk factors using binary-coded responses. All variables showed significant differences between women with and without PID (t-values: 2.75–7.89, p < 0.01). Women with histories of multiple partners, STIs, IUD use, abortion, or ectopic pregnancy were significantly more likely to have PID, confirming strong associations with these risk factors 

Statement Mean (R)Mean (P)t-valuep-value
I have heard about PID before3.63.24.28<0.001
I know the symptoms of PID3.53.14.01< 0.001
PID leads to serious complications3.63.23.88<0.001
I know where to get treatment3.53.14.00< 0.001
Regular check-ups help prevent PID3.73.34.37< 0.001

Table 10: Awareness Level of PID

(Source: Computed from Author’s survey data, 2025)

Table 10 presents the results of independent samples t-tests comparing PID awareness levels between reproductive-aged and perimenopause women across five key awareness items. In each case, reproductive-aged women showed significantly higher awareness, with mean scores ranging from 3.5 to 3.7, compared to 3.1 to 3.3 for perimenopause women. All t-values range from 3.88 to 4.37, and p-values are all less than 0.001, indicating strong statistical significance. 

Marriage TypeTotalChi-square χ² dfp-Value
Monogamy18012.3510.0004
Polygamy60   

Table 11: Type of Marriage and PID Prevalence

(Source: Computed from Author’s survey data, 2025)

Table 11 shows the Chi-square test which yields a calculated value of 12.35, at df = 1 and α = 0.05. This result is statistically significant (p > 0.0004), leading to rejection in the null hypothesis. This suggests that marital structure may influence sexual health risks, possibly due to increased exposure to multiple sexual partners or reduced autonomy in reproductive and perimenopause. 

Statementt-valuedfp-value
I seek medical care when I notice pelvic symptoms.4.253860.0001
I go for regular gynaecological check-ups.3.973830.0001
I complete prescribed antibiotics during infections.3.163920.0002
I practice safe sex.2.913960.0004
I’ve discussed PID with a healthcare provider.2.593860.010

Table 12: Health-Seeking Behavior

(Source: Computed from Author’s survey data, 2025)

Table 12 presents Independent Samples T-Test results assessing the association between health-seeking behaviours and PID diagnosis among reproductive and perimenopause women. All five behaviours showed statistically significant differences (p< 0.05), with higher mean scores reported by women without PID. This indicates that positive health-seeking practices are associated with lower PID prevalence. Therefore, the null hypothesis is rejected, confirming a significant relationship between health-seeking behaviour and PID diagnosis. 

Figure 1: PID Prevalence between Reproductive and Perimenopause Women

Figure 2: Symptoms and PID Diagnosis

Data were expressed as Mean ± SD, ****p<0.0001 is significant in all groups.

Figure 3: Risk Factor Association

Data were expressed as Mean ± SD, ****p<0.0001 is significant in all groups.

Figure 4: Awareness Level of PID

Data were expressed as Mean ± SD, ****p<0.0001 is significant in all groups.

Figure 5: Type of Marriage and PID Prevalence

Figure 6: Health-Seeking Behaviour

Data were expressed as Mean ± SD, ****p<0.0001 is significant in all groups.

4.0 Discussion

This study examined the prevalence, associated symptoms, risk factors, awareness, marital structure, and health-seeking behaviours related to pelvic inflammatory disease (PID) among reproductive and perimenopausal women. The findings revealed a significantly higher prevalence of PID among perimenopausal women (75%) compared with reproductive-aged women (45%), confirming a greater disease burden in older women. This observation supports earlier findings that identified PID as a persistent reproductive health problem among Nigerian women and globally [14,35,1]. The higher prevalence among perimenopausal women may reflect cumulative lifetime exposure to sexually transmitted infections (STIs), hormonal changes, and declining immune responses, as previously reported [33].

Strong associations were observed between PID and core clinical symptoms, including irregular menstruation, dyspareunia, pelvic pain, frequent urination, and difficulty conceiving. These findings highlight the importance of symptom recognition in PID diagnosis, particularly in resource-limited settings where laboratory confirmation may be limited. Similar symptom patterns have been documented in previous studies, which emphasise that delayed recognition and treatment may result in infertility and chronic pelvic pain [27,36,37].

Sexual and reproductive history significantly influenced PID occurrence. Women with previous STIs, multiple sexual partners, abortion history, intrauterine device (IUD) use, and ectopic pregnancy showed significantly higher PID prevalence. These findings are consistent with earlier reports identifying STIs, particularly Chlamydia trachomatis and Neisseria gonorrhoeae, as primary etiological agents of PID [2,4,8]. IUD use has also been linked to PID when insertion occurs in the presence of untreated cervical infections [17]. Additionally, sexual risk behaviours and reproductive tract trauma associated with abortion or ectopic pregnancy may increase susceptibility to ascending infections [16].

An important observation was the relationship between PID diagnosis and awareness. Women diagnosed with PID demonstrated significantly higher awareness levels than those without prior diagnosis, suggesting that awareness often follows clinical exposure rather than serving as a preventive factor. Similar findings have been reported, indicating that healthcare interaction improves disease knowledge and preventive practices [19,38]. This underscores the need for proactive public health education targeting undiagnosed women, as recommended in previous reproductive health studies [1,31].

Marital structure was also significantly associated with PID prevalence. Women in polygamous marriages demonstrated nearly threefold higher odds of PID compared with those in monogamous unions. This finding supports earlier evidence that expanded sexual networks and reduced autonomy in reproductive health decision-making may increase STI exposure in polygamous settings [33]. Such sociocultural factors highlight the importance of culturally sensitive reproductive health interventions in sub-Saharan Africa.

Health-seeking behaviour emerged as a protective factor against PID. Women who reported early medical consultation, routine gynaecological check-ups, completion of antibiotic treatment, safe sexual practices, and communication with healthcare providers showed significantly lower PID prevalence. These findings align with previous research demonstrating that early diagnosis, treatment adherence, and regular clinical monitoring reduce PID complications, including infertility, tubo-ovarian abscess, and chronic pelvic pain [28,39,19].

The findings of this study also align with global evidence identifying PID as a major contributor to infertility and chronic reproductive morbidity worldwide [13]. Associations between PID and adverse reproductive outcomes, including ectopic pregnancy and chronic pelvic pain, have been consistently reported [32,31]. Emerging research further suggests that hormonal changes and alterations in vaginal microbiota during the perimenopausal transition may increase susceptibility to infection, supporting the need for age-specific screening and preventive strategies [10,9].

Overall, this study highlights the multifactorial nature of PID among reproductive and perimenopausal women, emphasizing the combined influence of biological, behavioural, and sociocultural determinants. Addressing these factors through targeted education, improved healthcare access, and age-specific screening strategies is essential for reducing PID-related morbidity and improving reproductive health outcomes.

5.0 Conclusion

This study found a high prevalence (75%) of Pelvic Inflammatory Disease (PID) among reproductive and perimenopausal women, highlighting an often-overlooked public health concern. The persistence of PID in aging women is linked to cumulative reproductive exposures, age-related changes, and risk factors such as prior STIs, IUD use, multiple partners, abortion history, and polygamous unions. Common symptoms pelvic pain, vaginal discharge, and dyspareunia proved reliable for diagnosis, especially in low-resource settings. Although awareness was higher among diagnosed women, it followed rather than prevented illness, underscoring the need for proactive education. Improved outcomes were associated with timely care-seeking, regular check-ups, and treatment adherence, pointing to the need for integrated strategies combining education, early screening, and culturally sensitive interventions.

6. Recommendation

Based on the study's findings, the following recommendations are proposed:

  1. Intensify public awareness campaigns on PID symptoms, risks, and prevention, especially targeting perimenopausal women through community outreach and media.
  2. Integrate PID screening into regular reproductive health check-ups to enable early detection and treatment.
  3. Enhance access to affordable, quality healthcare services, particularly in rural areas, through subsidized treatments and mobile clinics.
  4. Train health workers to recognize and manage PID in older women, avoiding misdiagnosis related to menopause.
  5. Encourage condom use and partner involvement in prevention and treatment to reduce reinfection.

7. Clinical Implications

From a clinical standpoint, this study underscores the urgent need for targeted screening and diagnostic strategies for PID in both perimenopausal and reproductive-age women. This population is often overlooked in routine gynaecological care, with symptoms mistakenly attributed to menopausal transition or aging. Clinicians should maintain a high index of suspicion for PID in women presenting with pelvic pain, abnormal discharge, or menstrual irregularities, particularly when there is a history of STIs, intrauterine device use, or polygamous unions. Integrating PID-specific screening algorithms into regular gynaecologic evaluations and strengthening provider training on symptom recognition and age-specific risk factors will enhance early detection and treatment outcomes. At the public health level, education campaigns are essential to dispel misconceptions about PID, encourage prompt medical consultation, and promote STI screening and treatment adherence. Such measures will help prevent long-term complications, including infertility, chronic pelvic pain, and ectopic pregnancy, thereby improving women’s reproductive health across all age groups.

Declaration of conflict of interest:

The authors wish to declare that there are no potential conflicts of interest that could partially or fully prejudice the research report.

References

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Dr Elena Popa

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Dr Nikolaos Andreas Chrysanthakopoulos

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Robert W McGee

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Aibing Rao

I Appreciate the Opportunity to Share my Experience with the Journal of Clinical Research and Reports. The peer review process was timely and constructive, and the feedback provided helped improve the quality of our manuscript. The editorial office was professional, responsive, and supportive throughout the process, ensuring smooth communication and efficient handling of the submission. Overall, it was a positive experience collaborating with your team.

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Alla Konstantinovna Politova

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Perlat Kapisyzi

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Dr Ted Christopher

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Dr Mamoun Magzoub

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Mahmoud Kamal Moustafa Ahmed

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Dariusz Ziora

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Dr Jelle Lettinga

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Dr Rakhi Mishra

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S Munshi

I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.

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Husain Taha Radhi

I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.

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Dr Tong Ming Liu

We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.

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Dr Griffith

I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.

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Douglas Miyazaki

"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".

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Jesus Simal-Gandara

I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!

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Baheci Selen

Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.

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Bruno Chauffert

Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.

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Dr Suramya Dhamija

International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.

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Andreas Filippaios

Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.

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Raed Mualem

As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.

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Dr Shiming Tang

Dear Hao Jiang, to Journal of Nutrition and Food Processing We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.

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Hao Jiang

This is an acknowledgment for peer reviewers, editorial board of Journal of Clinical Research and Reports. They show a lot of consideration for us as publishers for our research article “Evaluation of the different factors associated with side effects of COVID-19 vaccination on medical students, Mutah university, Al-Karak, Jordan”, in a very professional and easy way. This journal is one of outstanding medical journal.

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Prof Sherif W Mansour

Dr. Bernard Terkimbi Utoo, I am happy to publish my scientific work in Journal of Women Health Care and Issues (JWHCI). The manuscript submission was seamless and peer review process was top notch. I was amazed that 4 reviewers worked on the manuscript which made it a highly technical, standard and excellent quality paper. I appreciate the format and consideration for the APC as well as the speed of publication. It is my pleasure to continue with this scientific relationship with the esteem JWHCI.

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Bernard Terkimbi Utoo

Testimony of Journal of Clinical Otorhinolaryngology: work with your Reviews has been a educational and constructive experience. The editorial office were very helpful and supportive. It was a pleasure to contribute to your Journal.

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Pedro Marques Gomes

Thank you most sincerely, with regard to the support you have given in relation to the reviewing process and the processing of my article entitled "Large Cell Neuroendocrine Carcinoma of The Prostate Gland: A Review and Update" for publication in your esteemed Journal, Journal of Cancer Research and Cellular Therapeutics". The editorial team has been very supportive.

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Anthony Kodzo-Grey Venyo

Dr. Katarzyna Byczkowska My testimonial covering: "The peer review process is quick and effective. The support from the editorial office is very professional and friendly. Quality of the Clinical Cardiology and Cardiovascular Interventions is scientific and publishes ground-breaking research on cardiology that is useful for other professionals in the field.

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Katarzyna Byczkowska

Journal of Neuroscience and Neurological Surgery. I had the experience of publishing a research article recently. The whole process was simple from submission to publication. The reviewers made specific and valuable recommendations and corrections that improved the quality of my publication. I strongly recommend this Journal.

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Orlando Villarreal

The peer-review process which consisted high quality queries on the paper. I did answer six reviewers’ questions and comments before the paper was accepted. The support from the editorial office is excellent.

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Sing-yung Wu

We would like to thank the Journal of Thoracic Disease and Cardiothoracic Surgery because of the services they provided us for our articles. The peer-review process was done in a very excellent time manner, and the opinions of the reviewers helped us to improve our manuscript further. The editorial office had an outstanding correspondence with us and guided us in many ways. During a hard time of the pandemic that is affecting every one of us tremendously, the editorial office helped us make everything easier for publishing scientific work. Hope for a more scientific relationship with your Journal.

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Layla Shojaie

Journal of Clinical Research and Reports I would be very delighted to submit my testimonial regarding the reviewer board and the editorial office. The reviewer board were accurate and helpful regarding any modifications for my manuscript. And the editorial office were very helpful and supportive in contacting and monitoring with any update and offering help. It was my pleasure to contribute with your promising Journal and I am looking forward for more collaboration.

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Mina Sherif Soliman Georgy

Journal of Women Health Care and Issues By the present mail, I want to say thank to you and tour colleagues for facilitating my published article. Specially thank you for the peer review process, support from the editorial office. I appreciate positively the quality of your journal.

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Ziemlé Clément Méda

Journal of Clinical Cardiology and Cardiovascular Intervention The submission and review process was adequate. However I think that the publication total value should have been enlightened in early fases. Thank you for all.

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Delcio G Silva Junior

Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. Auctoresonline publishing platform can be used to facilitate of optimal client-based services and should be added to health care professionals' repertoire of evidence-based health care resources.

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Virginia E. Koenig