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Synchrotron Micro and Macro ATR-FTIR Biospectroscopy for Bright and Sharp Chemical Shifting and Mapping of DNA/RNA in Single Cells

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Review Article | DOI: https://doi.org/10.31579/2834-5142/079

Synchrotron Micro and Macro ATR-FTIR Biospectroscopy for Bright and Sharp Chemical Shifting and Mapping of DNA/RNA in Single Cells

  • Alireza Heidari 1234

*Corresponding Author: Alireza Heidari, American International Standards Institute (AISI), Irvine, CA 3800, USA.

Citation: Alireza Heidari (2023), Synchrotron Micro and Macro ATR-FTIR Biospectroscopy for Bright and Sharp Chemical Shifting and Mapping of DNA/RNA in Single Cells, International Journal of Clinical Nephrology, 5(6); DOI:10.31579/2834-5142/079

Copyright: © 2023, Alireza Heidari. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Received: 13 December 2023 | Accepted: 18 December 2023 | Published: 29 December 2023

Keywords:

Abstract

My fibroma is an innocent, tender tissue new tumor that primarily affects toddlers and younger kids. most appear inside the pores and skin or underneath the pores and skin tissues, with a choice for the top and neck areas. We describe the magnet-based totally (MR) imaging and histopathologic findings of an unprecedented case of (into the muscle) my fibroma of the right deltoid in a wholesome 30-year-vintage male. MR imaging showed/advised about a nicely-surrounded (into the muscle) mass, with isointense sign on T1-weighted photographs, hyperintense signal on T2-weighed images, and a "target-signal" with (off to the aspect) rim improvement after gadolinium control. The (damage to a frame part) became surgically reduce out without a difficulty, and the histopathologic evaluation confirmed/advised about the typical morphologic and histochemical markers of my fibroma. We figure out that, although uncommon, my fibroma may be idea about/believed in the different viable diagnosis of adults with (damage to frame components) the above sign (capabilities/ qualities/ traits) [1-114]. 

Acknowledgement

This study was supported by the Cancer Research Institute (CRI) Project of Scientific Instrument and Equipment Development, the National Natural Science Foundation of the United Sates, the International Joint BioSpectroscopy Core Research Laboratory (BCRL) Program supported 

by the California South University (CSU), and the Key project supported by the American International Standards Institute (AISI), Irvine, California, USA.

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  71. A. Heidari, (2018) ,.“Gamma Linolenic Methyl Ester, 5–Heptadeca–5,8,11–Trienyl 1,3,4–Oxadiazole–2–Thiol, Sulphoquinovosyl Diacyl Glycerol, Ruscogenin, Nocturnoside B, Protodioscine B, Parquisoside–B, Leiocarposide, Narangenin, 7–Methoxy Hespertin, Lupeol, Rosemariquinone, Rosmanol and Rosemadiol Nano Molecules Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Cancer Cells, Tissues and Tumors Treatment under Synchrotron and Synchrocyclotron Radiations”, Int J Pharma Anal Acta, 2 (1): 007–014.
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  72. A. Heidari, (2018) ,.“Fourier Transform Infrared (FTIR) Spectroscopy, Attenuated Total Reflectance Fourier Transform Infrared (ATR–FTIR) Spectroscopy, Micro–Attenuated Total Reflectance Fourier Transform Infrared (Micro–ATR–FTIR) Spectroscopy, Macro–Attenuated Total Reflectance Fourier Transform Infrared (Macro–ATR–FTIR) Spectroscopy, Two–Dimensional Infrared Correlation Spectroscopy, Linear Two–Dimensional Infrared Spectroscopy, Non–Linear Two–Dimensional Infrared Spectroscopy, Atomic Force Microscopy Based Infrared (AFM–IR) Spectroscopy, Infrared Photodissociation Spectroscopy, Infrared Correlation Table Spectroscopy, Near–Infrared Spectroscopy (NIRS), Mid–Infrared Spectroscopy (MIRS), Nuclear Resonance Vibrational Spectroscopy, Thermal Infrared Spectroscopy and Photothermal Infrared Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation with the Passage of Time”, Glob Imaging Insights, Volume 3 (2): 1–14.
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  73. A. Heidari, (2018) ,.“Heteronuclear Single–Quantum Correlation Spectroscopy (HSQC) and Heteronuclear Multiple–Bond Correlation Spectroscopy (HMBC) Comparative Study on Malignant and Benign Human Cancer Cells, Tissues and Tumors under Synchrotron and Synchrocyclotron Radiations”, Chronicle of Medicine and Surgery 2.3: 144–156.
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  74. A. Heidari, (2018) ,.“Tetrakis [3, 5–bis (Trifluoromethyl) Phenyl] Borate (BARF)–Enhanced Precatalyst Preparation Stabilization and Initiation (EPPSI) Nano Molecules”, Medical Research and Clinical Case Reports 2.1: 113–126.
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  75. A. Heidari, (2018) ,.“Sydnone, Münchnone, Montréalone, Mogone, Montelukast, Quebecol and Palau’amine–Enhanced Precatalyst Preparation Stabilization and Initiation (EPPSI) Nano Molecules”, Sur Cas Stud Op Acc J. 1 (3).
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  76. A. Heidari, (2018) ,.“Fornacite, Orotic Acid, Rhamnetin, Sodium Ethyl Xanthate (SEX) and Spermine (Spermidine or Polyamine) Nanomolecules Incorporation into the Nanopolymeric Matrix (NPM)”, International Journal of Biochemistry and Biomolecules, Vol. 4: Issue 1, Pages 1–19.
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  77. A. Heidari, R. Gobato, (2018) ,.“Putrescine, Cadaverine, Spermine and Spermidine–Enhanced Precatalyst Preparation Stabilization and Initiation (EPPSI) Nano Molecules”, Parana Journal of Science and Education (PJSE)–v.4, n.5, (1–14) July 1.
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  78. A. Heidari, (2018) ,.“Cadaverine (1,5–Pentanediamine or Pentamethylenediamine), Diethyl Azodicarboxylate (DEAD or DEADCAT) and Putrescine (Tetramethylenediamine) Nano Molecules Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Cancer Cells, Tissues and Tumors Treatment under Synchrotron and Synchrocyclotron Radiations”, Hiv and Sexual Health Open Access Open Journal. 1 (1): 4–11.
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  79. A. Heidari, (2018) ,.“Improving the Performance of Nano–Endofullerenes in Polyaniline Nanostructure–Based Biosensors by Covering Californium Colloidal Nanoparticles with Multi–Walled Carbon Nanotubes”, Journal of Advances in Nanomaterials, Vol. 3, No. 1, Pages 1–28.
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  80. R. Gobato, A. Heidari, (2018) ,.“Molecular Mechanics and Quantum Chemical Study on Sites of Action of Sanguinarine Using Vibrational Spectroscopy Based on Molecular Mechanics and Quantum Chemical Calculations”, Malaysian Journal of Chemistry, Vol. 20 (1), 1–23.
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  81. A. Heidari, (2018),.“Vibrational Biospectroscopic Studies on Anti–Cancer Nanopharmaceuticals (Part I)”, Malaysian Journal of Chemistry, Vol. 20 (1), 33–73.
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  82. A. Heidari, (2018) ,.“Vibrational Biospectroscopic Studies on Anti–Cancer Nanopharmaceuticals (Part II)”, Malaysian Journal of Chemistry, Vol. 20 (1), 74–117.
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  83. A. Heidari, (2018) ,.“Uranocene (U(C8H8)2) and Bis(Cyclooctatetraene)Iron (Fe(C8H8)2 or Fe(COT)2)–Enhanced Precatalyst Preparation Stabilization and Initiation (EPPSI) Nano Molecules”, Chemistry Reports, Vol. 1, Iss. 2, Pages 1–16.
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  84. A. Heidari, (2018) ,.“Biomedical Systematic and Emerging Technological Study on Human Malignant and Benign Cancer Cells and Tissues Biospectroscopic Analysis under Synchrotron Radiation”, Glob Imaging Insights, Volume 3 (3): 1–7.
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  85. A. Heidari, (2018) ,.“Deep–Level Transient Spectroscopy and X–Ray Photoelectron Spectroscopy (XPS) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation”, Res Dev Material Sci. 7(2). RDMS.000659.
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  86. A. Heidari, (2018) ,.“C70–Carboxyfullerenes Nano Molecules Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Cancer Cells, Tissues and Tumors Treatment under Synchrotron and Synchrocyclotron Radiations”, Glob Imaging Insights, Volume 3 (3): 1–7.
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  87. A. Heidari, (2018) ,.“The Effect of Temperature on Cadmium Oxide (CdO) Nanoparticles Produced by Synchrotron Radiation in the Human Cancer Cells, Tissues and Tumors”, International Journal of Advanced Chemistry, 6 (2) 140–156.
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  88. A. Heidari, (2018) ,.“A Clinical and Molecular Pathology Investigation of Correlation Spectroscopy (COSY), Exclusive Correlation Spectroscopy (ECOSY), Total Correlation Spectroscopy (TOCSY), Heteronuclear Single–Quantum Correlation Spectroscopy (HSQC) and Heteronuclear Multiple–Bond Correlation Spectroscopy (HMBC) Comparative Study on Malignant and Benign Human Cancer Cells, Tissues and Tumors under Synchrotron and Synchrocyclotron Radiations Using Cyclotron versus Synchrotron, Synchrocyclotron and the Large Hadron Collider (LHC) for Delivery of Proton and Helium Ion (Charged Particle) Beams for Oncology Radiotherapy”, European Journal of Advances in Engineering and Technology, 5 (7): 414–426.
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  89. A. Heidari, (2018) ,.“Nano Molecules Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Cancer Cells, Tissues and Tumors Treatment under Synchrotron and Synchrocyclotron Radiations”, J Oncol Res; 1 (1): 1–20.
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  90. A. Heidari, (2018) ,.“Use of Molecular Enzymes in the Treatment of Chronic Disorders”, Canc Oncol Open Access J. 1 (1): 12–15.
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  91. A. Heidari, (2018) ,.“Vibrational Biospectroscopic Study and Chemical Structure Analysis of Unsaturated Polyamides Nanoparticles as Anti–Cancer Polymeric Nanomedicines Using Synchrotron Radiation”, International Journal of Advanced Chemistry, 6 (2) 167–189.
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  92. A. Heidari, (2018) ,.“Adamantane, Irene, Naftazone and Pyridine–Enhanced Precatalyst Preparation Stabilization and Initiation (PEPPSI) Nano Molecules”, Madridge J Nov Drug Res. 2 (1): 61–67.
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  93. A. Heidari, (2018) ,. “Heteronuclear Single–Quantum Correlation Spectroscopy (HSQC) and Heteronuclear Multiple–Bond Correlation Spectroscopy (HMBC) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation”, Madridge J Nov Drug Res, 2 (1): 68–74.
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  94. A. Heidari, R. Gobato, (2018) ,.“A Novel Approach to Reduce Toxicities and to Improve Bioavailabilities of DNA/RNA of Human Cancer Cells–Containing Cocaine (Coke), Lysergide (Lysergic Acid Diethyl Amide or LSD), Δ⁹–Tetrahydrocannabinol (THC) [(–)–trans–Δ⁹–Tetrahydrocannabinol], Theobromine (Xantheose), Caffeine, Aspartame (APM) (NutraSweet) and Zidovudine (ZDV) [Azidothymidine (AZT)] as Anti–Cancer Nano Drugs by Coassembly of Dual Anti–Cancer Nano Drugs to Inhibit DNA/RNA of Human Cancer Cells Drug Resistance”, Parana Journal of Science and Education (PJSE), v. 4, n. 6, pp. 1–17.
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  95. A. Heidari, R. Gobato, (2018) ,.“Ultraviolet Photoelectron Spectroscopy (UPS) and Ultraviolet–Visible (UV–Vis) Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation”, Parana Journal of Science and Education (PJSE), v. 4, n. 6, pp. 18–33.
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  96. R. Gobato, A. Heidari, A. Mitra, (2018) ,.“The Creation of C13H20BeLi2SeSi. The Proposal of a Bio–Inorganic Molecule, Using Ab Initio Methods for the Genesis of a Nano Membrane”, Arc Org Inorg Chem Sci 3 (4). AOICS.MS.ID.000167.
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  97. R. Gobato, A. Heidari, (2018) ,.“Using the Quantum Chemistry for Genesis of a Nano Biomembrane with a Combination of the Elements Be, Li, Se, Si, C and H”, J Nanomed Res.7 (4): 241‒252.
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  98. A. Heidari, (2018) ,.“Bastadins and Bastaranes–Enhanced Precatalyst Preparation Stabilization and Initiation (EPPSI) Nano Molecules”, Glob Imaging Insights, Volume 3 (4): 1–7.
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  99. A. Heidari, (2018) ,.“Fucitol, Pterodactyladiene, DEAD or DEADCAT (DiEthyl AzoDiCArboxylaTe), Skatole, the NanoPutians, Thebacon, Pikachurin, Tie Fighter, Spermidine and Mirasorvone Nano Molecules Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Cancer Cells, Tissues and Tumors Treatment under Synchrotron and Synchrocyclotron Radiations”, Glob Imaging Insights, Volume 3 (4): 1–8.
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  100. E. Dadvar, A. Heidari, (2018) ,.“A Review on Separation Techniques of Graphene Oxide (GO)/Base on Hybrid Polymer Membranes for Eradication of Dyes and Oil Compounds: Recent Progress in Graphene Oxide (GO)/Base on Polymer Membranes–Related Nanotechnologies”, Clin Med Rev Case Rep 5: 228.
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  101. A. Heidari, R. Gobato, (2018) ,.“First–Time Simulation of Deoxyuridine Monophosphate (dUMP) (Deoxyuridylic Acid or Deoxyuridylate) and Vomitoxin (Deoxynivalenol (DON)) ((3α,7α)–3,7,15–Trihydroxy–12,13–Epoxytrichothec–9–En–8–One)–Enhanced Precatalyst Preparation Stabilization and Initiation (EPPSI) Nano Molecules Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Cancer Cells, Tissues and Tumors Treatment under Synchrotron and Synchrocyclotron Radiations”, Parana Journal of Science and Education (PJSE), Vol. 4, No. 6, pp. 46–67.
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  102. A. Heidari, (2018) ,.“Buckminsterfullerene (Fullerene), Bullvalene, Dickite and Josiphos Ligands Nano Molecules Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Hematology and Thromboembolic Diseases Prevention, Diagnosis and Treatment under Synchrotron and Synchrocyclotron Radiations”, Glob Imaging Insights, Volume 3 (4): 1–7.
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  103. A. Heidari, (2018) ,.“Fluctuation X–Ray Scattering (FXS) and Wide–Angle X–Ray Scattering (WAXS) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation”, Glob Imaging Insights, Volume 3 (4): 1–7.
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  104. A. Heidari, (2018) ,.“A Novel Approach to Correlation Spectroscopy (COSY), Exclusive Correlation Spectroscopy (ECOSY), Total Correlation Spectroscopy (TOCSY), Incredible Natural–Abundance Double–Quantum Transfer Experiment (INADEQUATE), Heteronuclear Single–Quantum Correlation Spectroscopy (HSQC), Heteronuclear Multiple–Bond Correlation Spectroscopy (HMBC), Nuclear Overhauser Effect Spectroscopy (NOESY) and Rotating Frame Nuclear Overhauser Effect Spectroscopy (ROESY) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation”, Glob Imaging Insights, Volume 3 (5): 1–9.
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  105. A. Heidari, (2018) ,.“Terphenyl–Based Reversible Receptor with Rhodamine, Rhodamine–Based Molecular Probe, Rhodamine–Based Using the Spirolactam Ring Opening, Rhodamine B with Ferrocene Substituent, Calix[4]Arene–Based Receptor, Thioether + Aniline–Derived Ligand Framework Linked to a Fluorescein Platform, Mercuryfluor–1 (Flourescent Probe), N,N’–Dibenzyl–1,4,10,13–Tetraraoxa–7,16–Diazacyclooctadecane and Terphenyl–Based Reversible Receptor with Pyrene and Quinoline as the Fluorophores–Enhanced Precatalyst Preparation Stabilization and Initiation (EPPSI) Nano Molecules”, Glob Imaging Insights, Volume 3 (5): 1–9.
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  106. A. Heidari, (2018) ,.“Small–Angle X–Ray Scattering (SAXS), Ultra–Small Angle X–Ray Scattering (USAXS), Fluctuation X–Ray Scattering (FXS), Wide–Angle X–Ray Scattering (WAXS), Grazing–Incidence Small–Angle X–Ray Scattering (GISAXS), Grazing–Incidence Wide–Angle X–Ray Scattering (GIWAXS), Small–Angle Neutron Scattering (SANS), Grazing–Incidence Small–Angle Neutron Scattering (GISANS), X–Ray Diffraction (XRD), Powder X–Ray Diffraction (PXRD), Wide–Angle X–Ray Diffraction (WAXD), Grazing– Incidence X–Ray Diffraction (GIXD) and Energy–Dispersive X–Ray Diffraction (EDXRD) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation”, Glob Imaging Insights, Volume 3 (5): 1–10.
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  107. A. Heidari, (2018) ,.“Nuclear Resonant Inelastic X–Ray Scattering Spectroscopy (NRIXSS) and Nuclear Resonance Vibrational Spectroscopy (NRVS) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation”, Glob Imaging Insights, Volume 3 (5): 1–7.
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  108. A. Heidari, (2018) ,.“Small–Angle X–Ray Scattering (SAXS) and Ultra–Small Angle X–Ray Scattering (USAXS) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation”, Glob Imaging Insights, Volume 3 (5): 1–7.
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  109. A. Heidari, (2018) ,. “Curious Chloride (CmCl3) and Titanic Chloride (TiCl4)–Enhanced Precatalyst Preparation Stabilization and Initiation (EPPSI) Nano Molecules for Cancer Treatment and Cellular Therapeutics”, J. Cancer Research and Therapeutic Interventions, Volume 1, Issue 1, Pages 01–10.
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  110. R. Gobato, M. R. R. Gobato, A. Heidari, A. Mitra, (2018) ,.“Spectroscopy and Dipole Moment of the Molecule C13H20BeLi2SeSi via Quantum Chemistry Using Ab Initio, Hartree–Fock Method in the Base Set CC–pVTZ and 6–311G**(3df, 3pd)”, Arc Org Inorg Chem Sci 3 (5), Pages 402–409.
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  111. A. Heidari, (2018) ,.“C60 and C70–Encapsulating Carbon Nanotubes Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Cancer Cells, Tissues and Tumors Treatment under Synchrotron and Synchrocyclotron Radiations”, Integr Mol Med, Volume 5 (3): 1–8.
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  112. A. Heidari, (2018) ,.“Two–Dimensional (2D) 1H or Proton NMR, 13C NMR, 15N NMR and 31P NMR Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation with the Passage of Time”, Glob Imaging Insights, Volume 3 (6): 1–8.
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  113. A. Heidari, (2018) ,.“FT–Raman Spectroscopy, Coherent Anti–Stokes Raman Spectroscopy (CARS) and Raman Optical Activity Spectroscopy (ROAS) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation”, Glob Imaging Insights, Volume 3 (6): 1–8.
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  114. A. Heidari, (2018) ,.“A Modern and Comprehensive Investigation of Inelastic Electron Tunneling Spectroscopy (IETS) and Scanning Tunneling Spectroscopy on Malignant and Benign Human Cancer Cells, Tissues and Tumors through Optimizing Synchrotron Microbeam Radiotherapy for Human Cancer Treatments and Diagnostics: An Experimental Biospectroscopic Comparative Study”, Glob Imaging Insights, Volume 3 (6): 1–8.
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Dear Editorial Team, Clinical Medical Reviews and Reports. My experience with the journal was highly positive. The peer-review process was rigorous, constructive, and completed in a timely manner. The reviewers provided valuable comments that helped improve the quality and clarity of our manuscript. The editorial office was professional, responsive, and supportive throughout all stages of the publication process. Communication was clear and efficient, and any questions were addressed promptly. Overall, I found the journal to maintain high scientific standards and an excellent publication workflow. I would be pleased to consider submitting future work to this journal. Best wishes from, Elena Popa.

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Dr Elena Popa

It was my pleasure to submit my testimonial concerning the Reviewer Board of our Scientific Journal “Brain and Neurological Disorders”. The Reviewers focused on some modifications and their contribution was helpful. The ladies of our Editorial Office were also supported my efforts. It was my honor to have such a co-operation and I am looking forward for more collaboration.

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Dr Nikolaos Andreas Chrysanthakopoulos

Dear Grace Pierce, Editorial Coordinator of Journal of Clinical Research and Reports, Thank you for the speedy and efficient peer review process. I appreciate the fact that your peer reviewers do not take months to respond like with some other journals. I would also like to thank the editorial office for responding quickly to my questions. It is an excellent journal. I plan to submit more manuscripts in the future. Best wishes from, Robert W. McGee

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Robert W McGee

Dear Grace Pierce, Editorial Coordinator of Journal of Clinical Research and Reports, Working with you and your team on our recent publication in JCRR has been a truly wonderful and enjoyable experience. The responses were prompt, and the reviewers were patient, constructive, and highly professional. One reviewer in particular gave me the feeling that a professor was carefully reading and commenting on my coursework, which was deeply touching. The entire process was straightforward and hassle‑free, with no tedious online forms to complete. I highly recommend this journal. Best wishes from, DR Aibing Rao, Head of R&D

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Aibing Rao

I Appreciate the Opportunity to Share my Experience with the Journal of Clinical Research and Reports. The peer review process was timely and constructive, and the feedback provided helped improve the quality of our manuscript. The editorial office was professional, responsive, and supportive throughout the process, ensuring smooth communication and efficient handling of the submission. Overall, it was a positive experience collaborating with your team.

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Kashani Mehdi

Dear Mercy Grace, Editorial Coordinator of Obstetrics Gynecology and Reproductive Sciences, We would like to express our gratitude for your help at all stages of publishing and editing the article. The editors of the magazine answer all the necessary questions and help at every stage. We will definitely continue to cooperate and publish other works in the Obstetrics Gynecology and Reproductive Sciences! Best wishes from, Alla Konstantinovna Politova,

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Alla Konstantinovna Politova