Case Report | DOI: https://doi.org/10.31579/2690-1897/009
Departement of gastroenterology. Habib Thameur Hospital
Departement of pathology. Habib Thameur Hospital
*Corresponding Author: Sabbah Meriam. Departement of gastroenterology. Habib Thameur Hospital
Citation: Sabbah M, Trad D, Bellil N, Jouini R, Ouakaa A, Elloumi H, Bibani N, Gargouri D. (2019) Signet ring cell neuroendocrine tumor. Surgical Case Reports and Images, 2(1); Doi: 10.31579/2690-1897/009
Copyright: © 2019. Sabbah Meriam. This is an open-access article distributed under the termsof the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Received: 08 November 2019 | Accepted: 12 November 2019 | Published: 29 November 2019
Keywords: diabetes; hypertension;colonoscopy
A 63 years old woman with history of diabetes and hypertension, presented for bone pain. Pelvic X Ray showed multiple osteoconsensant lesions of the iliac wings, the sacrum and the femurs (figure 1). CT scan objectified multiple hepatic metastases with a laterorectal mass (figure 2). Colonoscopy showed aspect of extrinsic compression. Endoscopic ultrasound objectified a rectal mucosal lesion of 5x3,5 centimeters appearing in contact with the prostate (figure 3). Histologically, hepatic biopsy confirmed a tumor proliferation that was made of two architectural aspects independent cells, and trabeculolobular classical endocrine architecture with expression of synaptophysin on immunochemistry (figure 4).
A 63 years old woman with history of diabetes and hypertension, presented for bone pain. Pelvic X Ray showed multiple osteoconsensant lesions of the iliac wings, the sacrum and the femurs (figure 1). CT scan objectified multiple hepatic metastases with a laterorectal mass (figure 2). Colonoscopy showed aspect of extrinsic compression. Endoscopic ultrasound objectified a rectal mucosal lesion of 5x3,5 centimeters appearing in contact with the prostate (figure 3). Histologically, hepatic biopsy confirmed a tumor proliferation that was made of two architectural aspects independent cells, and trabeculolobular classical endocrine architecture with expression of synaptophysin on immunochemistry (figure 4).
Figure 1: Pelvic X Ray showed multiple osteoconsensant lesions of the iliac wings, the sacrum and the femurs
Figure 2: CT scan objectified multiple hepatic metastases with a laterorectal mass
Figure 3: Endoscopic ultrasound objectified a rectal mucosal lesion of 5x3, 5 centimeters appearing in contact with the prostate
Figure 4: Hepatic biopsy showing a tumor proliferation that was made of two architectural aspects independent cells, and trabeculolobular classical endocrine architecture with expression of synaptophysin on immunochemistry
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