AUCTORES
Globalize your Research
Research Article | DOI: https://doi.org/10.31579/2640-1053/151
1 Assistant Professor, Ph.D.,Department of Anthropology, Dinabandhu Mahavidyalaya, Bongaon-743235, West Bengal, India.
2 Former Research Scholar, Ph.D., Department of Anthropology, University of Calcutta.University College of Science, Technology & Agriculture, University of Calcutta, 35 Ballygunge Circular Road, Kolkata-700019, West Bengal, India.
3 Professor, Department of Anthropology, University of Calcutta, 35, Ballygunge circular road, Kolkata – 700019.
4 Associate Professor, Department of Anthropology, University of Calcutta, 35, Ballygunge circular road, Kolkata – 700019
*Corresponding Author: Piyali Das, Assistant Professor, Ph.D., Department of Anthropology, Dinabandhu Mahavidyalaya, Bongaon-743235, West Bengal, India.
Citation: Piyali Das, Biswarup Dey, Arup R. Bandyopadhyay and Diptendu Chatterjee, (2023), Role of finger dermatoglyphics in prognosis of Gastric Cancer among the Bengalee population of West Bengal, India, J. Cancer Research and Cellular Therapeutics, 7(4); DOI:10.31579/2640-1053/151
Copyright: © 2023, Piyali Das. this is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Received: 10 July 2023 | Accepted: 19 July 2023 | Published: 28 July 2023
Keywords: finger dermatoglyphics; gastric cancer; bengalee population
Cancer is the second most common disease among the populations of developing countries. Therefore, the relevance of prognosis at the early stage has an extensive impact. The cost-effective, non-invasive dermatoglyphics method seems useful for cancer identification and plays a critical role in the early prediction of different types of cancer worldwide. In view of the above, bilateral rolled fingerprints of 50 histopathological confirmed Gastric Cancer patients (M -17, F -33) from various Clinics in Kolkata and 50 controls without any family history of cancer (M -26, F -24) from the Bengalee Population of West Bengal, India were compared. The standard ink method was used to collect the finger prints. The results revealed noteworthy features regarding the finger patterns. Significant (p<0.05) presence of the whorl finger pattern might be used as an additional criterion to compare the cancer patients with the controls. More over significant (p<0.05) greater value of PII plays the key role the in the prognosis of cancer patients to a certain extent. Results envisaged that finger dermatoglyphics has the potential for early detection of patients with gastric cancer and stimulates further studies with large sample sizes to get a better insightful vision. Furthermore, the mortality rate may be declined by the early detection of the disease, and to conduct this early diagnosis must be ensured with ethnic group-specific mass screening insinuation.
Cancer, the second largest cause of death worldwide, extensively influences global morbidity and mortality pattern [1]. India shares a high cancer burden, often related to late-stage detection and low penetration of cancer–screening programs [2]. Cancer research has made remarkable progress and discoveries, which included the discovery of immune checkpoint inhibition mechanisms, exosomes, microbiome, and immunotherapy leading to further understanding of the mechanisms governing cancer proliferation, invasion, and metastasis, as well as the development of cancer detection and therapeutic methods [3]. The dermatoglyphic pattern, unique in every individual and remains unchanged throughout life, is developed during embryogenesis (between 4 weeks and five months), and the environment has little influence [4]. In recent eras, the application of dermatoglyphics has been restricted not only to personal identification or forensic sciences. There is an inevitable shift in the paradigm of dermatoglyphic research where the intensive use of dermatoglyphics is noticed in medico-legal purposes and genetic disorders [5, 6]. The relationship of differential patterns has also been reported earlier from various chromosomal aberrations [7, 8, 9]. Apart from chromosomal aberrations, studies reported significant differential patterns of quantitative and qualitative parameters in hereditary genetic diseases [10, 11].
Studies on finger dermatoglyphics revealed noteworthy features irrespective of different types of cancer [1]. Dermatoglyphics traits have been used as effective non invasive low-cost tools for early detection of different kinds of cancer [12]. Carcinoma Cervix patients [13], Prostate Cancer [14], and Breast Cancer [15] were studied to find alliance with dermatoglyphic traits.
Gastric cancer is the third cause of death and the fifth most prevalent cancer globally [16]. The global burden of gastric cancer vindicated 1.1 million new cases in 2020, with a higher incidence rate in males than females across different countries, mainly Eastern countries [17]. Gastric cancer, the fourth leading cause of global mortality, requires urgent attention for better prevention [18]. Digitopalmar dermatoglyphic traits assert the existence of a genetic predisposition for the development of gastric cancer [19]. Both the stomach and finger patterns are developed during the 6 to 13 weeks of embryogenesis, fully formed at about seven months of fetus development [20]. The fundamental assumption is that since many genes take part in the formation of dermatoglyphic characters, it is possible that genes that predispose to familial disease may, by pleiotropy, also influence the ridge patterns so that particular constellations of dermatoglyphic features may be characteristic of a particular disease [21]. However, few studies have been conducted on dermatoglyphics and Gastric Cancers [22]. Hence, it requires further comprehensive ethnic group-specific studies for a better perceptive conclusion. Therefore, this study attempts to find the association between finger dermatoglyphics and Gastric Cancer among the Bengalee population of West Bengal India.
50 histopathological confirmed Gastric Cancer patients (M -17, F -33) from different Clinics in Kolkata and 50 controls (M -26, F -24) from the Bengalee Population were studied. The standard ink method for taking hands and fingerprints, as described by Schaumann and Alter was used [23]. The dermatoglyphic traits considered in the present study include digital dermatoglyphic pattern types. Digital dermatoglyphic patterns were classified Galton : arch, loop, and whorl, according to the number of triradii in each pattern type [24]. An arch has no triradii, a loop has one, and whorls have two triradii. The loops are further divided into two categories. The open loops at the radial and ulnar sides are called radial and ulnar loops. The results obtained were treated with descriptive and inferential statistics. SPSS version 18.0 was used for data analysis, and the cut off value was set at 95% probability limits
Comparatively, the current investigation confirmed that gastric cancer patients have significant (p<0>
Groups
| Whorl | Loop | Arche | Chi-Square | df | p | |
| R1 | Case | 24 | 26 | 0 | 32.541*# | 2 | 0.000 |
| Control | 0 | 48 | 2 | ||||
| R2 | Case | 20 | 27 | 3 | 7.325*# | 2 | 0.02 |
| Control | 8 | 39 | 3 | ||||
| R3 | Case | 3 | 47 | 0 | 6.00*# | 2 | 0.04 |
| Control | 0 | 47 | 3 | ||||
| R4 | Case | 9 | 41 |
| 3.677* | 1 | 0.05 |
| Control | 2 | 48 | |||||
| R5 | Case | 0 | 50 |
| 0.51# | 1 | 0.47 |
| Control | 2 | 48 | |||||
| L1 | Case | 15 | 35 | 0 | 21.25*# | 2 | 0.000 |
| Control | 0 | 45 | 5 | ||||
| L2 | Case | 20 | 30 | 0 | 15.982*# | 2 | 0.000 |
| Control | 4 | 43 | 3 | ||||
| L3 | Case | 12 | 38 | 0 | 7.309*# | 2 | 0.02 |
| Control | 4 | 43 | 3 | ||||
| L4 | Case | 6 | 44 | 0 | 3.106# | 2 | 0.21 |
| Control | 6 | 41 | 3 | ||||
| L5 | Case | 9 | 41 |
| 3.677*# | 1 | 0.05 |
| Control | 2 | 48 | |||||
Table 1: Finger-wise distribution of the Finger Pattern Types
*p<0>
| Whorl | Loop | Arche | Chi-Square | df | p | ||
| LH | Case | 62 | 188 | 0 | 43.638*# | 2 | 0.0000 |
| Control | 16 | 220 | 14 | ||||
| RH | Case | 56 | 194 | 0 | 39.527*# | 2 | 0.0000 |
| Control | 12 | 230 | 8 |
Table 2: Bilateral distribution of the Finger Pattern Types (total) among the Cancer patients and the controls
*p<0>
| Cancer Patients | Control | |
| PII | x̄±SD | x̄±SD |
| LH | 1.25±0.11* | 1.01±0.06 |
| RH | 1.22±0.21* | 1.02±0.07 |
| *p=0.0000 | ||
Table 3: Bilateral distribution of the Pattern Intensity Index (PII) among the Cancer patients and the controls
The dermatoglyphic analysis could be a helpful tool for early genetic diagnosis. It could be a valuable tool for identifying people with a genetic predisposition to develop certain genetic disorders for a better insightful approach to clench the situation [1]. Finger dermatoglyphics are pivotal in assessing the relationship with breast cancer [25] in India and also the other Asian countries [26]. Studies indicated that breast cancer reveals noteworthy features regarding finger dermatoglyphics [27]. This alliance might be due to the pleiotropic effect, as finger ridge patterns formation associated with the development of breast as well as with the stomach within the same intrauterine phase of fetus development. The result of the present study revealed significantly higher existence of whorl patterns which is corroborated with other studies [28]. Earlier studies reported extensive notable outcomes [9, 28] and therefore further attempts are required to facilitate better scenario in order to comprehend. Such association between finger dermatoglyphics and gastric cancer which may ensure early detection of the disease and prioritize equitable access to prevention, ultimately influence the mortality rate of the particular ethnic group for better assessment of the national health burden.
The burden rate of cancer increases daily, eventually generating significant challenges in its prevention and control. Therefore, early detection and prognosis have become essential to direct morbidity and mortality patterns. Thus, more in-depth studies using large sample sizes in multi-ethnic populations are the urgent constraint, and finger dermatoglyphics can be used as a cost-effective imperative prognostic tool, which is equally significant to deal with cancer, a global health burden.
Declarations
Ethical approval and consent of participate
Ethical approval was provided by University of Calcutta (No. CU/BIOETHICS/HUMAN/2304/2022). Written consent was obtained from each participant of the present study.
Consent to Publication
Consent for publication in a research journal was obtained from all the studied participants.
Availability of Data and materials
All the data sets used during the present study to conduct the study are available to the corresponding author uponreasonable request.
Competing interest
This research work is original and has not been published elsewhere, nor is it currently under consideration for publication elsewhere. We have no conflicts of interest to disclose.
Funding
The Department of Anthropology, U.C.S.T.A., University of Calcutta,has assisted with partial funding,
Acknowledgment
The authors are grateful to the study participants and the Department of Anthropology, U.C.S.T.A., University of Calcutta, for providing all necessary facilities for the successful conduction of the present study.
Author’s contribution
PD and BD are the prime investigators of this research work. PD and BD reviewed the literature, analyzed the data, and prepared the manuscript. ARB and DC reviewed the analyzed data and the manuscript. PD, BD, ARB, and DC edited and finalized the manuscript.
Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. Auctoresonline publishing platform can be used to facilitate of optimal client-based services and should be added to health care professionals' repertoire of evidence-based health care resources.
Journal of Clinical Cardiology and Cardiovascular Intervention The submission and review process was adequate. However I think that the publication total value should have been enlightened in early fases. Thank you for all.
Journal of Women Health Care and Issues By the present mail, I want to say thank to you and tour colleagues for facilitating my published article. Specially thank you for the peer review process, support from the editorial office. I appreciate positively the quality of your journal.
Journal of Clinical Research and Reports I would be very delighted to submit my testimonial regarding the reviewer board and the editorial office. The reviewer board were accurate and helpful regarding any modifications for my manuscript. And the editorial office were very helpful and supportive in contacting and monitoring with any update and offering help. It was my pleasure to contribute with your promising Journal and I am looking forward for more collaboration.
We would like to thank the Journal of Thoracic Disease and Cardiothoracic Surgery because of the services they provided us for our articles. The peer-review process was done in a very excellent time manner, and the opinions of the reviewers helped us to improve our manuscript further. The editorial office had an outstanding correspondence with us and guided us in many ways. During a hard time of the pandemic that is affecting every one of us tremendously, the editorial office helped us make everything easier for publishing scientific work. Hope for a more scientific relationship with your Journal.
The peer-review process which consisted high quality queries on the paper. I did answer six reviewers’ questions and comments before the paper was accepted. The support from the editorial office is excellent.
Journal of Neuroscience and Neurological Surgery. I had the experience of publishing a research article recently. The whole process was simple from submission to publication. The reviewers made specific and valuable recommendations and corrections that improved the quality of my publication. I strongly recommend this Journal.
Dr. Katarzyna Byczkowska My testimonial covering: "The peer review process is quick and effective. The support from the editorial office is very professional and friendly. Quality of the Clinical Cardiology and Cardiovascular Interventions is scientific and publishes ground-breaking research on cardiology that is useful for other professionals in the field.
Thank you most sincerely, with regard to the support you have given in relation to the reviewing process and the processing of my article entitled "Large Cell Neuroendocrine Carcinoma of The Prostate Gland: A Review and Update" for publication in your esteemed Journal, Journal of Cancer Research and Cellular Therapeutics". The editorial team has been very supportive.
Testimony of Journal of Clinical Otorhinolaryngology: work with your Reviews has been a educational and constructive experience. The editorial office were very helpful and supportive. It was a pleasure to contribute to your Journal.
Dr. Bernard Terkimbi Utoo, I am happy to publish my scientific work in Journal of Women Health Care and Issues (JWHCI). The manuscript submission was seamless and peer review process was top notch. I was amazed that 4 reviewers worked on the manuscript which made it a highly technical, standard and excellent quality paper. I appreciate the format and consideration for the APC as well as the speed of publication. It is my pleasure to continue with this scientific relationship with the esteem JWHCI.
This is an acknowledgment for peer reviewers, editorial board of Journal of Clinical Research and Reports. They show a lot of consideration for us as publishers for our research article “Evaluation of the different factors associated with side effects of COVID-19 vaccination on medical students, Mutah university, Al-Karak, Jordan”, in a very professional and easy way. This journal is one of outstanding medical journal.
Dear Hao Jiang, to Journal of Nutrition and Food Processing We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.
As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.
Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.
International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.
Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.
Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.
I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!
"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".
I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.
We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.
I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.
I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.
I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.
Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.
“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.
Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
