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short communication | DOI: https://doi.org/10.31579/2693-4779/197
1The First College of Clinical Medical Science, China Three Gorges University, Yichang, China.
2Institute of Digestive Disease, China Three Gorges University, Yichang, China.
3Department of Gastroenterology, Yichang Central People’s Hospital, Yichang, China.
*Corresponding Author: Wei Liu, Institute of Digestive Disease, China Three Gorges University, Yichang, China.
Citation: Qi Yang, Wei Liu, (2024), Rectal perineurioma, Clinical Research and Clinical Trials, 10(1); DOI:10.31579/2693-4779/197
Copyright: © 2024, Wei Liu. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 06 March 2024 | Accepted: 15 April 2024 | Published: 20 May 2024
Keywords: colonoscopy screening; endoscopic mucosal; histopathological
A 48-year-old woman presented for colonoscopy screening. She reported no weight loss and family history of gastrointestinal cancer. Physical examination and laboratory findings were unremarkable
A 48-year-old woman presented for colonoscopy screening. She reported no weight loss and family history of gastrointestinal cancer. Physical examination and laboratory findings were unremarkable. Lower gastrointestinal endoscopy identified a sessile protruded, well-circumscribed, and flat elevated lesion within the rectum, which measured approximately 8 mm in diameter (Figure. 1A).
Endoscopic mucosal resection was performed. Histopathological examination confirmed proliferation of band spindle cells with ovoid to elongated nuclei and indistinct cytoplasma (Figure. 1B). On immunostaining,
the spindle cells stained strongly with for CD34 (Figure. 1C), GLUT-1 (Figure. 1D) and claudin-1 (Figure. 1E), and was negative for CD117, EMA, SMA, and S-100 protein. No signs of malignancy was found.
Therefore, she received the diagnosis of rectal perineurioma. The patient recovered uneventfully and was discharged after endoscopic surgery. Rectal perineurioma is a rare benign mucosal lesion, comprised a proliferation of bland spindle cells, which expressed markers of perineurial differentiation.1,2,3 The patient was followed up for 6 months without recurrence.
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