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Review Article | DOI: https://doi.org/10.31579/2641-0419/549
physicist Russian New University, 22 Radio Street, Moscow, 105005, Russia.
*Corresponding Author: Vladimir Ivanovich Ermoshkin, physicist Russian New University, 22 Radio Street, Moscow, 105005, Russia.
Citation: Vladimir I. Ermoshkin, (2026), Oncology, as Well as Most Cardiovascular and Metabolic Diseases, Occur Mainly due to Stress and Uncontrolled Leakage of Blood from the Arteries into the Veins, J Clinical Cardiology and Cardiovascular Interventions, 9(3); DOI:10.31579/2641-0419/549
Copyright: © 2026, Vladimir Ivanovich Ermoshkin. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 21 January 2026 | Accepted: 24 February 2026 | Published: 03 March 2026
Keywords: oncology, cancer, atherosclerosis, metabolic syndrome, abdominal obesity, diabetes mellitus, pulmonary hypertension, arteriovenous anastomoses, bloodletting
Annotation This article is a hypothesis dedicated to the search for the causes and mechanisms of the development of oncological, some cardiovascular and metabolic diseases in humans. For a very long time, approaches to solving the problems of causation of these diseases were not productive enough. And in 2025-2026, from the author's point of view, there may be some progress in understanding the causes of these diseases
Goal Here is the usual description of the causes of cancer given by standard medicine. The main cause of cancer is genetic mutations. In the process of cell division in the body, errors in genes sometimes occur. If the immune mechanisms that are supposed to prevent and correct these errors do not work, a cell with damaged DNA develops and divides repeatedly, disobeying the body's controlling systems. As a result, an education is formed, which is called a malignant tumor. But the root causes of the genetic mutations remain unknown. The expanded purpose of this study is to rethink the metabolic processes occurring in the human body, not only taking into account genetic, biological, biochemical and chemical processes, but also taking into account some physical processes that, oddly enough, turned out to be decisive not only in the development of cancer, but also atherosclerosis, metabolic syndrome, and pulmonary hypertension [1 - 5].
The results of the critical analysis
The connection between cancer and emotional turmoil has been known for a long time. In the 2nd century AD, the Roman physician Galen noticed that cheerful women were less likely to get cancer than gloomy and sullen ones. In 1853, the English surgeon and pathologist James Paget in his work "Lectures on surgical pathology" suggested that depression has a direct influence on the development of cancer.
He found that the incidence of cancer in people is directly proportional to strong feelings — excitement, anxiety, disappointment. But the first study, supported by statistical data, was published only in 1926. Elida Evans, a student of Carl Gustav Jung, published a book called "Cancer Research from a psychological point of view" (by the way, the preface to it was written by Thomas Jung himself). The book presented the results of an examination of 100 cancer patients. Evans found out that shortly before the disease developed, many of them lost important emotional connections — they experienced the death of a loved one, lost their job or home.
In the 1970s, a new scientific field appeared - psychoncology. This is one of the branches of oncology that studies the impact of cancer on human psychological health, as well as the relationship between emotional state and carcinogenesis, i.e. the process of malignant tumor formation.
The following two paragraphs list the ailments and diseases that modern standard medicine indicates under stress. It is known that with chronic stress, stress hormones (cortisol, adrenaline) are constantly released into the bloodstream, and this depletes the body. The heart, brain, blood vessels, and endocrine system are affected. The main symptoms of chronic stress: excessive sweating, cold in the extremities, headache, fatigue, trembling, rapid pulse, chest pain, bruxism, muscle spasms, stool disorders (constipation, diarrhea), nausea and vomiting, weight gain or, conversely, weight loss, mood swings, sleep disorders, decreased concentration, infectious diseases, withdrawal, depression, pessimistic mood, lack of sexual desire, feeling of excitement, anxiety, decreased attentiveness, forgetfulness, absent-mindedness, other cognitive impairments, problems falling asleep, sleep, alcohol addiction, drug addiction, and others.
Stress can be a trigger for the development of serious diseases. Among them are arterial hypertension, myocardial infarction, arrhythmia, metabolic syndrome and prolonged hormonal imbalance, obesity, which cannot always be corrected by diet, colitis, gastritis and other diseases of the gastrointestinal tract, psoriasis, acne, alopecia, depression, neurosis, and other mental pathologies. Stress can also lead to immunodeficiency or disruption of the immune system. At the same time, it is the immune system that is the main weapon against cancer. She knows how to recognize abnormal cells and destroy them. But something unknown seems to be preventing the immune system from quickly finding and destroying these cells.
Question: what have doctors and patients been ignoring for centuries?
Answer: they do not take into account the work of large arteriovenous anastomoses (AVA) in the large circle of blood circulation (BCC) [3, 6]!
3It turns out that due to the fact that a person's blood pressure (BP) increases during moments of stress, large arteriovenous anastomoses can open for a short time [3]. In fact, anastomoses are emergency pressure valves. Arterial blood is transfused into the venous channel through open anastomoses [7, 8]. At the same time, systemic blood pressure decreases.
Usually, patients who have anastomosis openings are diagnosed with vegetative vascular dystonia at an outpatient appointment. Thus, during the cardiometric examination of the patient [8], signs of the opening of arteriovenous anastomoses of the BCC were found (Fig.1).
Figure. 1. Cardiometric signs of AVA opening. In the picture: an ECG at the top, a rheogram at the bottom, marked "AVA=ABA" – this is the opening of arteriovenous anastomoses (shunts). A rheogram is a graphical representation of changes in the electrical resistance of living tissues, organs, or body areas when a high–frequency and low-power electric current is passed through them.
If a person is exposed to frequent stress, excitement, and anxiety for a long time and does not have any useful physical and respiratory activity, then the total amount of blood transfused through the anastomoses into the veins may be sufficient for a gradual deterioration of health. What are the consequences of manipulating arteriovenous anastomoses that open and close seconds later for, for example, several tens of minutes or even several hours, i.e. during a prolonged stressful situation? This means that arterial blood replenishes the venous pool in small doses all the time, changing the composition of the "venous" blood. In fact, venous blood becomes mixed, with an increased content of oxygen, nutrients, hormones, antibodies, etc.
Blood flowing, for example, through anastomosis from the superior mesenteric artery into the portal vein mixes and then enters the liver. They suffer from a violation of the composition of such "venous" blood, primarily the liver, then the myocardium, lungs, and kidneys already in the arterial basin. Over time, fatty alcoholic or non-alcoholic liver disease may occur with this mode of operation.
The same reason probably contributes to abdominal (visceral) obesity and ascites. But the point of view of standard medicine is different here: fatty liver disease due to hereditary causes, overeating, hormonal imbalance. Obviously, these issues require additional research and clarification.
The leakage of arterial blood into the venous basin through the anastomosis between the superior mesenteric artery and the portal vein (this anastomosis is probably number 1 in importance), after another portion of the transfusion, gradually increases the pressure in the venous basin, which increases the stagnation of venous blood in the pelvis and legs, especially when the spine is vertical. Stagnation worsens the situation for any person, as the accumulation of blood and intercellular fluid in the legs progresses, serious diseases occur: varicose veins, thrombosis, damage to the valves of the leg veins, diabetes mellitus, etc.
Recall that the volume of arterial blood cannot change significantly in a particular person. Let's say it is equal to 850 ml. Organizational adjustments must maintain this volume at an unchanged level. The volume of blood output by the ventricles of the heart: on average 65-70 ml, and under load up to 125 ml. On the other hand, the volume of venous blood can vary over a wide range. On average, it is 4-5 times larger than the volume of arterial blood. We can assume that the venous volume is 4400 ml. The question arises: "What is the mechanism for replenishing the lost volume of arterial blood during stress leaks?" After all, if the Frank-Starling law on equal volumes of discharge through the left and right ventricles of the heart is valid, then there is only one solution – an increase in pulmonary pressure, an increase in capacity, frequency and strength of heart contractions in order to replenish the lost volume of arterial blood. From the point of view of the author's theory, these volume replenishments due to blood leaks are the "cause of pulmonary hypertension"! That is why the walls of arterial vessels of the small circle of blood circulation thicken, fibrosis appears [9, 10]. But standard medicine often calls the cause of pulmonary hypertension "idiopathic."
the work [13], carried out by medical specialists based on extensive experience in observing patients with pulmonary hypertension, refers to such a trigger of pulmonary hypertension as "portal hypertension". In the same document, there is an observation about a non-specific clinical manifestation of pulmonary hypertension as "noise of arteriovenous blood discharge." These two characteristic observations may confirm the author's hypothesis about the periodic opening of the "arteriovenous anastomosis number 1", after which portal and pulmonary pressure can really rise!
Numerous other observations confirm that, according to standard medicine, concomitant diseases with increased pulmonary pressure are all the same coronary heart disease, diabetes mellitus, chronic obstructive pulmonary disease, rheumatic arthritis, sleep apnea, and others. So, there is an external, more general reason. And this reason is physical: a lack of arterial blood due to "blood leaks through the anastomoses of the BCC into the veins" due to an increase in systemic blood pressure. Sometimes doctors say [11]: "By the way, about blood pressure”.
It is often lower than normal in pulmonary hypertension. Which is paradoxically combined with the sky-high pressure figures in the small circle of blood circulation (MCC): as a result of the disease, the left parts of the heart suffer, giving too weak a cardiac output."
The author's comment. Blood pressure below normal is a confirmation of the fact that due to the stresses of opening / closing the "anastomosis number 1" blood pressure can fluctuate widely: sometimes above normal, then below normal. All this is due to leaks and a slow decrease in the total arterial blood volume of a large circulatory system! At the initial stage of a stressful situation, a decrease in blood volume in the aorta occurs, among other things, due to a decrease in the capillary and tissue volume of blood in peripheral organs (hands and feet get cold)!
But at the final stage of a stressful situation, a hypertensive crisis may occur! This is when, due to leaks, there is not enough blood in the large arteries and in the aorta! Thus, the entire group of diseases mentioned above (atherosclerosis, metabolic syndrome, pulmonary hypertension, and possibly oncology) occurs due to arterial blood leaks through anastomoses during moments of prolonged psychological stress.
But let's return to the description of oncology. Due to leaks, not only venous, but also arterial blood changes its composition, because the liver and kidneys cannot cope with the neutralization of substances that have passed through two ways: either through all natural body filters, or through anastomoses. In fact, substances may appear in the arterial blood that should not enter the arterioles and capillaries of the working cells.
These are toxins, carbon dioxide, damaged cells, metabolic products, microthrombi, excess minerals, medicinal substances, etc.
These "unnecessary or excessive" substances can linger or "get stuck" in various internal organs and in the skin. In fact, the "dirt" presented above can remain in small arteries, arterioles, capillaries, venules, or in the intercellular fluid. Over time, these "excess" blood fragments accumulate, which can lead to health problems. In fact, there are (micro) blockages of blood circulation in any areas of any of the human organs. To deliver these "excess" blood fragments through small vessels to the venous bed, the central nervous system must raise systemic blood pressure. It turns out that due to contamination of the arterial bed at the capillary level, one of the main causes of increased systemic pressure in humans may arise.
In the presence of "dirty" blood, small areas of tissue with slow or stopped blood circulation constantly appear and disappear. In these areas, in conditions of a shortage of fresh blood, damage and blood clots are likely to appear. Then only one cell with mutated DNA can appear. Such a cell develops, divides repeatedly, not obeying the body's immune system, because immune cells also cannot get inside the blocking zones. As a result, a malignant tumor may form.
Statistics show that cancer can occur in any organ, but most often it affects the skin, lungs, gastrointestinal tract, breast, prostate and liver.
Let's remember that skin cancer comes first. The hijama procedure demonstrates to us that some organs and tissues in humans are affected by substances that are "unnecessary" for the body, "stuck" at least in human skin and in adjacent organs [12]! You can get acquainted with the pictures of the procedure results on the Internet. The first thing that can be observed in a patient after the hijama procedure is a decrease in systemic blood pressure, and this looks optimistic!
In addition, there are foreign studies on the hijama procedure, but for some reason there are problems with the expanded publication of these data.
Author's opinion: it is necessary to conduct new modern research in Russia and publish them. This will reduce speculation about the danger of hijama!
Here are some "secret data". In foreign studies [14] on hijama, it is indicated that the blood released during the procedure contains: non-viable cells, deformed and outdated; acids (uric, lactic, etc.); endotoxins; purulent exudate; heavy metals; cholesterol; a large number of pathogenic microflora; other elements that impede regenerative processes in the body. Microscopic studies of blood extracted during hijam also reveal, for example: distinctive shapes of red blood cell cells (anisocytosis, poikilocytosis); lack of hemoglobin (hypochromia); decrease in the number of white blood cells.
So far, we are offered to accept the point of view of the Ministry of Health, and consider [14] that there is no clinical evidence of the effectiveness of hijama for 2500 years — existing studies are supposedly few, have a weak methodology and do not allow us to conclude about the benefits of the procedure.
The author's suggestion
The main thing is that it is necessary to somehow detect the fact of blood leaks through the anastomosis and replenish the lost volume of arterial blood without delay.
It is necessary to invent a device that will record the opening and closing of large anastomoses, including anastomosis number 1, i.e. it is necessary to "see" your body's reaction to possible stress from an independent source of information and timely perform preventive procedures that will be offered to us in the near future as optimal: physical, respiratory, medicinal procedures, combined.
What do we know about the leaks now? The author suggests that a person can feel the flow of arterial blood into the veins. At this time, a person experiences unusual "pulsations in the navel area," or "pulsations in the abdomen." Doctors sometimes tell such patients: This may be due to prolonged sitting in an uncomfortable position, after stress, heavy physical exertion, or certain diseases of the abdominal organs. After a while, the pulsations may disappear without a trace. Check out the mentions of this phenomenon on the Internet from patients who tell doctors about these pulsations. There are a lot of such messages from women and men (thousands of messages). Doctors answer: either it is an aortic aneurysm, which is a rare and dangerous case, or it is a variant of the norm, which happens very often. The usual recommendations are to check the abdominal organs in the clinic.
Why does the author recommend doing breathing and physical exercises in cases of abdominal pulsation? Yes, because a person in a small circle of blood circulation also has arteriovenous anastomoses between the bronchial artery and the bronchial vein! The number of such anastomoses in the lung under normal conditions is 25-30 [15]! Why did nature provide for the presence of anastomoses in such quantity?
Apparently, in order to be able to quickly replenish the arterial pool of the BCC, for example, when a person is injured with significant losses of arterial blood of the BCC! In order to compensate for blood loss through small circle anastomoses of BCC.
This requires deep breathing movements to quickly replenish the arterial pool of the MCC, even if the additional blood from the MCC is only partially oxygenated. After all, a lack of arterial blood volume in the arterial basin is very dangerous, it is a rapid hypovolemic shock with loss of consciousness!
People! Avoid stressful situations. Engage in breathing practices and physical exercises! The benefits of the procedures have been proven. Try the hijama procedure.
Unfortunately, the author has not yet undergone any hijam procedure, but there is a desire!
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To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.
"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".
I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.
Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.
We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.
My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.
To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina
Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.
Dear Ashley Rosa, Editorial Coordinator of the journal - Psychology and Mental Health Care. " The process of obtaining publication of my article in the Psychology and Mental Health Journal was positive in all areas. The peer review process resulted in a number of valuable comments, the editorial process was collaborative and timely, and the quality of this journal has been quickly noticed, resulting in alternative journals contacting me to publish with them." Warm regards, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. I appreciate the journal (JCCI) editorial office support, the entire team leads were always ready to help, not only on technical front but also on thorough process. Also, I should thank dear reviewers’ attention to detail and creative approach to teach me and bring new insights by their comments. Surely, more discussions and introduction of other hemodynamic devices would provide better prevention and management of shock states. Your efforts and dedication in presenting educational materials in this journal are commendable. Best wishes from, Farahnaz Fallahian.
Dear Maria Emerson, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. I am delighted to have published our manuscript, "Acute Colonic Pseudo-Obstruction (ACPO): A rare but serious complication following caesarean section." I want to thank the editorial team, especially Maria Emerson, for their prompt review of the manuscript, quick responses to queries, and overall support. Yours sincerely Dr. Victor Olagundoye.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. Many thanks for publishing this manuscript after I lost confidence the editors were most helpful, more than other journals Best wishes from, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Agrippa Hilda, Editorial Coordinator, Journal of Neuroscience and Neurological Surgery. The entire process including article submission, review, revision, and publication was extremely easy. The journal editor was prompt and helpful, and the reviewers contributed to the quality of the paper. Thank you so much! Eric Nussbaum, MD
Dr Hala Al Shaikh This is to acknowledge that the peer review process for the article ’ A Novel Gnrh1 Gene Mutation in Four Omani Male Siblings, Presentation and Management ’ sent to the International Journal of Clinical Case Reports and Reviews was quick and smooth. The editorial office was prompt with easy communication.
Dear Erin Aust, Editorial Coordinator, Journal of General Medicine and Clinical Practice. We are pleased to share our experience with the “Journal of General Medicine and Clinical Practice”, following the successful publication of our article. The peer review process was thorough and constructive, helping to improve the clarity and quality of the manuscript. We are especially thankful to Ms. Erin Aust, the Editorial Coordinator, for her prompt communication and continuous support throughout the process. Her professionalism ensured a smooth and efficient publication experience. The journal upholds high editorial standards, and we highly recommend it to fellow researchers seeking a credible platform for their work. Best wishes By, Dr. Rakhi Mishra.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. The peer review process of the journal of Clinical Cardiology and Cardiovascular Interventions was excellent and fast, as was the support of the editorial office and the quality of the journal. Kind regards Walter F. Riesen Prof. Dr. Dr. h.c. Walter F. Riesen.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. Thank you for publishing our article, Exploring Clozapine's Efficacy in Managing Aggression: A Multiple Single-Case Study in Forensic Psychiatry in the international journal of clinical case reports and reviews. We found the peer review process very professional and efficient. The comments were constructive, and the whole process was efficient. On behalf of the co-authors, I would like to thank you for publishing this article. With regards, Dr. Jelle R. Lettinga.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, I would like to express my deep admiration for the exceptional professionalism demonstrated by your journal. I am thoroughly impressed by the speed of the editorial process, the substantive and insightful reviews, and the meticulous preparation of the manuscript for publication. Additionally, I greatly appreciate the courteous and immediate responses from your editorial office to all my inquiries. Best Regards, Dariusz Ziora
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation, Auctores Publishing LLC, We would like to thank the editorial team for the smooth and high-quality communication leading up to the publication of our article in the Journal of Neurodegeneration and Neurorehabilitation. The reviewers have extensive knowledge in the field, and their relevant questions helped to add value to our publication. Kind regards, Dr. Ravi Shrivastava.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, Auctores Publishing LLC, USA Office: +1-(302)-520-2644. I would like to express my sincere appreciation for the efficient and professional handling of my case report by the ‘Journal of Clinical Case Reports and Studies’. The peer review process was not only fast but also highly constructive—the reviewers’ comments were clear, relevant, and greatly helped me improve the quality and clarity of my manuscript. I also received excellent support from the editorial office throughout the process. Communication was smooth and timely, and I felt well guided at every stage, from submission to publication. The overall quality and rigor of the journal are truly commendable. I am pleased to have published my work with Journal of Clinical Case Reports and Studies, and I look forward to future opportunities for collaboration. Sincerely, Aline Tollet, UCLouvain.
Dear Ms. Mayra Duenas, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. “The International Journal of Clinical Case Reports and Reviews represented the “ideal house” to share with the research community a first experience with the use of the Simeox device for speech rehabilitation. High scientific reputation and attractive website communication were first determinants for the selection of this Journal, and the following submission process exceeded expectations: fast but highly professional peer review, great support by the editorial office, elegant graphic layout. Exactly what a dynamic research team - also composed by allied professionals - needs!" From, Chiara Beccaluva, PT - Italy.
Dear Maria Emerson, Editorial Coordinator, we have deeply appreciated the professionalism demonstrated by the International Journal of Clinical Case Reports and Reviews. The reviewers have extensive knowledge of our field and have been very efficient and fast in supporting the process. I am really looking forward to further collaboration. Thanks. Best regards, Dr. Claudio Ligresti
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation. “The peer review process was efficient and constructive, and the editorial office provided excellent communication and support throughout. The journal ensures scientific rigor and high editorial standards, while also offering a smooth and timely publication process. We sincerely appreciate the work of the editorial team in facilitating the dissemination of innovative approaches such as the Bonori Method.” Best regards, Dr. Matteo Bonori.
I recommend without hesitation submitting relevant papers on medical decision making to the International Journal of Clinical Case Reports and Reviews. I am very grateful to the editorial staff. Maria Emerson was a pleasure to communicate with. The time from submission to publication was an extremely short 3 weeks. The editorial staff submitted the paper to three reviewers. Two of the reviewers commented positively on the value of publishing the paper. The editorial staff quickly recognized the third reviewer’s comments as an unjust attempt to reject the paper. I revised the paper as recommended by the first two reviewers.
Dear Maria Emerson, Editorial Coordinator, Journal of Clinical Research and Reports. Thank you for publishing our case report: "Clinical Case of Effective Fetal Stem Cells Treatment in a Patient with Autism Spectrum Disorder" within the "Journal of Clinical Research and Reports" being submitted by the team of EmCell doctors from Kyiv, Ukraine. We much appreciate a professional and transparent peer-review process from Auctores. All research Doctors are so grateful to your Editorial Office and Auctores Publishing support! I amiably wish our article publication maintained a top quality of your International Scientific Journal. My best wishes for a prosperity of the Journal of Clinical Research and Reports. Hope our scientific relationship and cooperation will remain long lasting. Thank you very much indeed. Kind regards, Dr. Andriy Sinelnyk Cell Therapy Center EmCell
Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. It was truly a rewarding experience to work with the journal “Clinical Cardiology and Cardiovascular Interventions”. The peer review process was insightful and encouraging, helping us refine our work to a higher standard. The editorial office offered exceptional support with prompt and thoughtful communication. I highly value the journal’s role in promoting scientific advancement and am honored to be part of it. Best regards, Meng-Jou Lee, MD, Department of Anesthesiology, National Taiwan University Hospital.
Dear Editorial Team, Journal-Clinical Cardiology and Cardiovascular Interventions, “Publishing my article with Clinical Cardiology and Cardiovascular Interventions has been a highly positive experience. The peer-review process was rigorous yet supportive, offering valuable feedback that strengthened my work. The editorial team demonstrated exceptional professionalism, prompt communication, and a genuine commitment to maintaining the highest scientific standards. I am very pleased with the publication quality and proud to be associated with such a reputable journal.” Warm regards, Dr. Mahmoud Kamal Moustafa Ahmed
Dear Maria Emerson, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews’, I appreciate the opportunity to publish my article with your journal. The editorial office provided clear communication during the submission and review process, and I found the overall experience professional and constructive. Best regards, Elena Salvatore.
Dear Mayra Duenas, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews Herewith I confirm an optimal peer review process and a great support of the editorial office of the present journal
Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. I am really grateful for the peers review; their feedback gave me the opportunity to reflect on the message and impact of my work and to ameliorate the article. The editors did a great job in addition by encouraging me to continue with the process of publishing.
Dear Cecilia Lilly, Editorial Coordinator, Endocrinology and Disorders, Thank you so much for your quick response regarding reviewing and all process till publishing our manuscript entitled: Prevalence of Pre-Diabetes and its Associated Risk Factors Among Nile College Students, Sudan. Best regards, Dr Mamoun Magzoub.
International Journal of Clinical Case Reports and Reviews is a high quality journal that has a clear and concise submission process. The peer review process was comprehensive and constructive. Support from the editorial office was excellent, since the administrative staff were responsive. The journal provides a fast and timely publication timeline.
Dear Maria Emerson, Editorial Coordinator of International Journal of Clinical Case Reports and Reviews, What distinguishes International Journal of Clinical Case Report and Review is not only the scientific rigor of its publications, but the intellectual climate in which research is evaluated. The submission process is refreshingly free of unnecessary formal barriers and bureaucratic rituals that often complicate academic publishing without adding real value. The peer-review system is demanding yet constructive, guided by genuine scientific dialogue rather than hierarchical or authoritarian attitudes. Reviewers act as collaborators in improving the manuscript, not as gatekeepers imposing arbitrary standards. This journal offers a rare balance: high methodological standards combined with a respectful, transparent, and supportive editorial approach. In an era where publishing can feel more burdensome than research itself, this platform restores the original purpose of peer review — to refine ideas, not to obstruct them Prof. Perlat Kapisyzi, FCCP PULMONOLOGIST AND THORACIC IMAGING.
Dear Mayra Duenas, Editorial Coordinator of the journal IJCCR, I write here a little on my experience as an author submitting to the International Journal of Clinical Case Reports and Reviews (IJCCR). This was my first submission to IJCCR and my manuscript was inherently an outsider’s effort. It attempted to broadly identify and then make some sense of life’s under-appreciated mysteries. I initially had responded to a request for possible submissions. I then contacted IJCCR with a tentative topic for a manuscript. They quickly got back with an approval for the submission, but with a particular requirement that it be medically relevant. I then put together a manuscript and submitted it. After the usual back-and-forth over forms and formality, the manuscript was sent off for reviews. Within 2 weeks I got back 4 reviews which were both helpful and also surprising. Surprising in that the topic was somewhat foreign to medical literature. My subsequent updates in response to the reviewer comments went smoothly and in short order I had a series of proofs to evaluate. All in all, the whole publication process seemed outstanding. It was both helpful in terms of the paper’s content and also in terms of its efficient and friendly communications. Thank you all very much. Sincerely, Ted Christopher, Rochester, NY.
Dear Grace Pierce, Editorial Coordinator of the journal IJCCR, I had a very positive experience with Auctores - Journal throughout the publication process. The Editorial Team was highly responsive, professional, and supportive at every stage. I would like to extend my sincere thanks to the Editor: Grace Pierce, for her guidance and assistance. The peer-review process was smooth and constructive, helping improve the quality of my work. I would gladly recommend Auctores Journal to fellow researchers and authors. Dr. SABITA SINHA, Medical Oncologist, MD (Electro Homeopathy).
Dear Maria Emerson, Editorial Coordinator of - Journal of Clinical Research and Reports. ''I am pleased to provide this testimonial following the publication of our recent case report in this journal. The peer review process was rigorous, constructive, thorough, and conducted in a timely manner. The reviewers’ comments were thoughtful, detailed, and highly constructive, contributing substantially to the refinement, clarity, and scientific robustness of our manuscript. The process was conducted with professionalism and academic integrity throughout. The support provided by the editorial office was exemplary. Communication was consistently prompt, clear, and courteous at all stages of the submission and publication process. The editorial team demonstrated a high level of organization and responsiveness, ensuring that all queries were addressed efficiently and that the process remained transparent and well-coordinated. The overall quality of the journal is reflected in its strong editorial standards, commitment to scientific excellence, and dedication to publishing clinically meaningful research. It has been a privilege to publish our work in this journal, and we would welcome the opportunity to contribute further in the future.'' Best wishes from, Dr. Efstratios Trogkanis, Cardiologist.
Dear Reader: We have published several articles in the Auctores Publishing, LLC, journal, Clinical Medical Reviews and Reports in recent years (CMRR). This is an ‘open access’ journal and the following are our observations. From the initial invitation to submit an article, to the final edits of galley proofs, we have found CMRR personnel to be professional, responsive, rapid and thorough. This entire process begins with Catherine Mitchell, Editorial Coordinator. She is simply outstanding, and, I believe, unparalleled in her capacity. I cannot imagine a more responsive and dedicated Editorial Coordinator. As I read the dates and timing of her correspondence with us, it seems that she never sleeps. I hope Auctores Publishing, LLC, appreciates her efforts as much as these authors do. Thank you to Auctores Publishing, LLC, to the Editorial Staff/Board, and to Catherine Mitchell from a grateful author(s).
