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Case Report | DOI: https://doi.org/10.31579/2639-4162/286
*Corresponding Author: Suresh Kishanrao, Family Physician & Public Health Consultant, Bengaluru, Karnataka, India.
Citation: Suresh Kishanrao, (2025), Never too Late to Reduce Weight with Chronotype Tailored Diet & Adjuvant Therapy for Obesity & Metabolic Health, J. General Medicine and Clinical Practice, 8(9); DOI:10.31579/2639-4162/286
Copyright: © 2025, Suresh Kishanrao. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Received: 21 June 2025 | Accepted: 21 August 2025 | Published: 31 August 2025
Keywords: metabolic syndrome; a chronotype-adapted diet; adjuvant therapy
Meal timing and the type of diet are crucial factors influencing metabolic health and obesity. Misaligned meal timing, particularly late-night eating, and diets high in processed foods and sugars can disrupt circadian rhythms, negatively impact metabolism and increase the likelihood of weight gain and related health issues. Circadian Rhythm or the body's internal clock, regulates various bodily functions, including metabolism. Meal timing that aligns with this rhythm can optimize metabolic processes. Consistent meal timings, during daylight hours, cultivated better insulin response to regulate blood sugar levels, help regulate appetite hormones that in turn prevent overeating and influence metabolic flexibility. If Metabolic health is disturbed due to a cluster of conditions including abdominal obesity, high blood pressure, impaired fasting glucose, high triglyceride levels, and low HDL cholesterol level and MASLD is found to be affecting approximately 25% of the population in India. Metabolic disorders disrupt normal metabolism, which is the complex set of chemical reactions that maintain life and enable growth, repair, and reproduction. This constellation is triggered by insulin resistance and its resultant hyperinsulinemia. The two most important and universally agreed causes of insulin resistance are increased body fat (particularly central obesity) and physical inactivity. Materials and Methods: This article is an outcome of application of Chronotype Tailored Diet & Adjuvant integrated Therapy on a case Obesity, MASLD, Rheumatoid Arthritis complimented by the author with relevant literature review. Outcome: Initial Inflammation Reduction using allopathic medications which reduced joints pain motivating her for regular exercises, ii) The Diet treatment plan was tailored based on Chronotype to the patient's specific needs and medical history which heled to reduce weight, iii) Combining Allopathy, Ayurvedic Panchakarma with yoga and Meditation therapy proved to be effective in physical and mental wellbeing and iv) Dietary changes and stress management played a crucial role in the patient's recovery.
Circadian Rhythm; insulin response Central Obesity; RA= Rheumatoid Arthritis; MASLD= Metabolic dysfunction-associated steatotic liver disease;
Most middle- and high-income people gain or have persistent overweight & Obesity which is associated with a high risk of chronic diseases beyond type 2 diabetes and increased all-cause mortality. The great relief from recent studies is that people who reduce excess weight in midlife can roughly halve their risk of developing chronic disease later in life, reaffirming the importance of lifestyle in achieving & maintaining a healthy weight through physical activity & prioritizing nutrient-rich foods which improve metabolic function, potentially leading to weight management and reduced risk of obesity-related diseases. Insulin inhibits fat breakdown, so it contributes to weight gain [1]. Meal timing and the type of diet are crucial factors influencing metabolic health and obesity. Misaligned meal timing, particularly late-night eating, and diets high in processed foods and sugars can disrupt circadian rhythms, negatively impact metabolism and increase the likelihood of weight gain and related health issues. Conversely consuming meals at regular, daylight hours help reduce weight gain or even lose weight. Metabolic Syndrome is a clustering of specific risk factors, namely, central obesity, raised blood pressure, impaired fasting glucose, raised triglycerides, low levels of high-density lipoprotein -cholesterol (HDL-C) & Metabolic dysfunction-associated steatotic liver disease MASLD. This constellation is triggered by insulin resistance and its resultant hyperinsulinemia [2].
Circadian Rhythm or the body's internal clock, regulates various bodily functions, including metabolism. Meal timing that aligns with this rhythm can optimize metabolic processes. If meals are consumed at regular times, particularly during daylight hours, the body's insulin response is more efficient, helping to regulate blood sugar levels. Consistent meal timing also helps regulate appetite hormones, potentially leading to better control over food intake and prevent overeating. Meal timing also influences metabolic flexibility, which is the body's ability to switch between using carbohydrates and fats for energy [3]. On the other hand, eating at irregular times, especially late at night, disrupts the circadian rhythm and negatively impact metabolism leading to i) Increased fat storage contributing to weight gain and obesity ii) decreases insulin sensitivity, potentially increasing the risk of type 2 diabetes iii) disrupts circadian rhythms and appetite hormones, leading to increased hunger and overeating. A chronotype-adapted diet involves adjusting eating schedule & macronutrient distribution to align with our body's natural sleep-wake cycle, to optimize metabolic processes by timing meals to coincide with individual peak periods of wakefulness & activity. A chronotype-adapted diet, therefore, is more effective than a standard low-calorie diet in improving body composition, metabolic health, and gut microbiota in overweight or obese individuals, especially among evening chronotypes who face greater challenges with conventional dietary strategies. This article is based on a case recently managed by the author applying Chronotype Tailored Diet & Adjuvant Therapy for Obesity, MASLD, Rheumatoid Arthritis complimented with relevant literature review.
54 years old, Female, IT Software consultant at a senior level, working with an international agency, demanding working from early evening to midnight, presented with history of severe multiple joint pains, difficulty in walking, Fatigue, and breathlessness on exertion especially climbing even 10 steps and disrupted sleep for the past 9 months. History revealed that she had Irregular food habits and timings, leading to digestive issues. Physical examination revealed a short, stout, fair lady with more central obesity. Her height was 55 inches; weight = 70 kg and abdominal girth was 38 inches. The thyroid gland was enlarged and on inquiry she reported that it had been there for 5 years. Clinical examination of CVS was normal but Respiratory systems on auscultation revealed mild wheezing- a high-pitched whistling sound, during exhalation.
Her Anthropometry and BMI worked out using the formula:
= 70/19600x1000
=70/1.96= 35.7
Underweight: <18>
Investigations: Blood for Thyroid hormones & RA factors, Chest X ray, and Abdominal CT scan
Based on clinical examination, and investigations she was diagnosed as a Case of “Hypothyroidism, asthma, arthritis and early MASLD”
Management:
Smaller breakfast, lunch and a larger dinner, considering her needs. An evening type, like her, find it beneficial to have a larger meal later in the day or evening. As our body's natural 24-hour cycle influences various bodily functions, including metabolism. By eating in sync with our circadian rhythm, we improve digestion, nutrient absorption, and overall metabolic health.
Outcomes:
Reduction in Waist Circumference: The patient showed a significant reduction in waist circumference from 96.5 cms to 85 cms, indicating a decrease in central obesity over a period of 6 months. Improved Physical Health: She experienced relief from joint pain, improved breathing, and increased mobility by the end of 4 weeks, that motivated her for more exercises thereafter. Enhanced Mental Well-being: The patient reported reduced stress levels and improved sleep patterns after about 6 weeks Overall Improvement: The integrated approach of Ayurveda, meditation and yoga, along with initial anti-inflammatory drugs, lifestyle counseling, resulted in a positive impact on the patient's overall health and well-being. MASLD: Due to the changed dietary modification, a CT scan after 3 months had shown arrest of MASLD and by six months it was reversed near 80%.
Key Factors for this case’s Success:
This case report highlights the potential of integrated therapies, including Ayurveda, Meditation and yoga, in managing central obesity and improving overall health in individuals, particularly in the Indian context.
Obesity and its associated health complications have become a global public health concern, necessitating innovative approaches to weight management. Although the negative effects of obesity on health are well known, a few old studies have demonstrated long-term health benefits among individuals with sustained weight loss beyond its association with decreased diabetes risk and beyond heart attacks like heart attack, stroke, cancer, asthma, chronic obstructive pulmonary disease, and overall mortality. One such publication demonstrated that people have a large degree of control over their own health and can protect themselves from many illnesses including age-related diseases just by reducing excess weight in midlife achieved without weight-loss injections or surgical interventions [1]. One emerging area of research focuses on the influence of chronotype, an individual’s preferred timing for daily activities, on eating habits, weight regulation, and metabolic health. Recent observational studies suggest that the misalignment between an individual’s chronotype and external cues, such as meal timing, do contribute to metabolic dysregulation and obesity, though the evidence from intervention studies is still limited [4].
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a group of liver diseases that happen when your body stores lots of fat in the liver causing {steatotic/fatty) liver disease (SLD). Over time, this fat in the liver causes inflammation in the liver. Until recently, it was known as nonalcoholic fatty liver disease (NAFLD.) In early stages this condition is reversible by dietary changes and physical exercises [6].
The human body's natural 24-hour cycle influences various bodily functions, including metabolism. By eating in sync with the circadian rhythm, we improve digestion, nutrient absorption, and overall metabolic health. Aligning meals with an individual’s circadian rhythm is more beneficial than a routine three helpings a day. In essence, a chronotype-adapted diet is a personalized approach to eating that recognizes the importance of aligning our mealtimes with our body's natural rhythms to potentially optimize health and well-being [3,4].
A chronotype-adapted diet involves adjusting eating schedule & macronutrient distribution to align with our body's natural sleep-wake cycle. This approach aims to optimize metabolic processes by timing meals to coincide with our peak periods of wakefulness & activity. Chronotypes are our body's natural inclination towards a specific sleep-wake pattern. There are generally three main chronotypes: i) Morning types (larks): Tend to be most alert and active in the morning and prefer to wake and sleep early ii) Evening types (owls): Tend to be most alert and active in the evening and prefer to wake and sleep late iii) Intermediate types: Fall somewhere between morning and evening types. A chronotype-adapted diet suggests that one must eat most of calories when our metabolism is most active i.e., For morning types, must have a larger breakfast and lunch, with a smaller dinner. For evening types, a larger dinner or later meals is beneficial. By aligning meal timing with your body's natural rhythms, we experience more effective weight loss, gain or maintenance. This approach helps regulate blood sugar levels, improve insulin sensitivity, and optimize lipid profiles. Eating in sync with our circadian rhythm indirectly improves sleep patterns and positively impacts our gut microbiome [3].
A recent of total of 150 overweight and obese females and males aged between 18 and 65 years with a body mass index (BMI) ≥ 25 kg/m2, excluding individuals with Cancer, kidney or liver disease, inflammatory bowel disease, cognitive decline, and psychiatric disease, and drug therapies interfering dietary interventions. The primary outcome observed was weight change from baseline. Secondary outcomes are (1) body mass index (BMI) and fat mass change from baseline; (2) lipid and glycemic profile change from baseline (total cholesterol, LDL-cholesterol, HDL-cholesterol, triglycerides, fasting glucose); and (3) fecal microbiota profile and short-chain fatty acids (SCFAs) change from baseline. The results showed that a chronotype-adapted diet is a personalized approach to eating that recognizes the importance of aligning our mealtimes with our body's natural rhythms to potentially optimize health and well-being [2].
In another recent study researchers conducted a retrospective study to identify clinical factors that predict successful and sustained weight loss in 897 patients with MASLD (mean age, 61.6 years; 57.1% men; mean BMI, 30.3). Cases were referred between January 2019 and December 2021, with follow-up occurring between 18 and 24 months at four Italian tertiary centers. The diagnosis of MASLD was confirmed if patients had hepatic steatosis on ultrasound and at least one cardiometabolic risk factor, such as a BMI ≥ 25 or high waist circumference, fasting glucose levels ≥ 100 mg/dL or type 2 diabetes, blood pressure ≥ 130/85 mm Hg, triglyceride levels ≥ 150 mg/dL, or low levels of high-density lipoprotein cholesterol. The takeaway from the study include; i) Over a median duration of 21 months, 18.3% of patients achieved at least 7% weight loss, with 8.5% losing 7%-10% and 9.8% losing more than 10% of their baseline weight ii) Higher baseline BMI was associated with increased odds of weight loss, with BMI 30-34.9 (adjusted odds ratio [aOR], 1.95;) and BMI ≥ 35 (aOR, 2.08; 95%) associated with at least 7% weight loss iii) Nutritionist support (aOR, 2.04;), liver stiffness measurement ≥ 10 kPa (aOR, 1.70;), and bilirubin levels ≥ 1.2 mg/dL (aOR, 2.12;) were independent predictors of achieving at least 7% weight loss. The use of GLP-1 agonists was significantly associated with an increased likelihood of losing at least 7% weight (aOR, 1.85;) [4].
Although the negative effects of obesity on health are well known, a recent publication highlights that people have a large degree of control over their own health and can protect themselves from many illnesses including age-related diseases just by reducing excess weight. In the ages of 40-50 years. Such weight reduction can be achieved without weight-loss medications or surgical interventions. Individuals who reached a healthy weight in midlife have long-term health outcomes comparable with those who maintained a healthy weight throughout adulthood. It’s always worth losing weight, even those who reach a normal weight at 50 or later can still see health benefits. Establishing a consistent meal schedule, with meals timed to align with Individual’s natural sleep-wake cycle, choosing a diet including plenty of fruits, vegetables, whole grains, lean proteins, & healthy fats. Intermittent fasting or time-restricted eating (TRE) also adds value. A comprehensive approach to MASLD management, encompassing medical, nutritional and lifestyle interventions remain crucial for all patients. For those without predictive factors or already exhibit early stages of MASLD close follow-up & early consideration of additional treatments are warranted to maximize therapeutic benefit.
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My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.
To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina
Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.
Dear Ashley Rosa, Editorial Coordinator of the journal - Psychology and Mental Health Care. " The process of obtaining publication of my article in the Psychology and Mental Health Journal was positive in all areas. The peer review process resulted in a number of valuable comments, the editorial process was collaborative and timely, and the quality of this journal has been quickly noticed, resulting in alternative journals contacting me to publish with them." Warm regards, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. I appreciate the journal (JCCI) editorial office support, the entire team leads were always ready to help, not only on technical front but also on thorough process. Also, I should thank dear reviewers’ attention to detail and creative approach to teach me and bring new insights by their comments. Surely, more discussions and introduction of other hemodynamic devices would provide better prevention and management of shock states. Your efforts and dedication in presenting educational materials in this journal are commendable. Best wishes from, Farahnaz Fallahian.
Dear Maria Emerson, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. I am delighted to have published our manuscript, "Acute Colonic Pseudo-Obstruction (ACPO): A rare but serious complication following caesarean section." I want to thank the editorial team, especially Maria Emerson, for their prompt review of the manuscript, quick responses to queries, and overall support. Yours sincerely Dr. Victor Olagundoye.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. Many thanks for publishing this manuscript after I lost confidence the editors were most helpful, more than other journals Best wishes from, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Agrippa Hilda, Editorial Coordinator, Journal of Neuroscience and Neurological Surgery. The entire process including article submission, review, revision, and publication was extremely easy. The journal editor was prompt and helpful, and the reviewers contributed to the quality of the paper. Thank you so much! Eric Nussbaum, MD
Dr Hala Al Shaikh This is to acknowledge that the peer review process for the article ’ A Novel Gnrh1 Gene Mutation in Four Omani Male Siblings, Presentation and Management ’ sent to the International Journal of Clinical Case Reports and Reviews was quick and smooth. The editorial office was prompt with easy communication.
Dear Erin Aust, Editorial Coordinator, Journal of General Medicine and Clinical Practice. We are pleased to share our experience with the “Journal of General Medicine and Clinical Practice”, following the successful publication of our article. The peer review process was thorough and constructive, helping to improve the clarity and quality of the manuscript. We are especially thankful to Ms. Erin Aust, the Editorial Coordinator, for her prompt communication and continuous support throughout the process. Her professionalism ensured a smooth and efficient publication experience. The journal upholds high editorial standards, and we highly recommend it to fellow researchers seeking a credible platform for their work. Best wishes By, Dr. Rakhi Mishra.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. The peer review process of the journal of Clinical Cardiology and Cardiovascular Interventions was excellent and fast, as was the support of the editorial office and the quality of the journal. Kind regards Walter F. Riesen Prof. Dr. Dr. h.c. Walter F. Riesen.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. Thank you for publishing our article, Exploring Clozapine's Efficacy in Managing Aggression: A Multiple Single-Case Study in Forensic Psychiatry in the international journal of clinical case reports and reviews. We found the peer review process very professional and efficient. The comments were constructive, and the whole process was efficient. On behalf of the co-authors, I would like to thank you for publishing this article. With regards, Dr. Jelle R. Lettinga.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, I would like to express my deep admiration for the exceptional professionalism demonstrated by your journal. I am thoroughly impressed by the speed of the editorial process, the substantive and insightful reviews, and the meticulous preparation of the manuscript for publication. Additionally, I greatly appreciate the courteous and immediate responses from your editorial office to all my inquiries. Best Regards, Dariusz Ziora
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation, Auctores Publishing LLC, We would like to thank the editorial team for the smooth and high-quality communication leading up to the publication of our article in the Journal of Neurodegeneration and Neurorehabilitation. The reviewers have extensive knowledge in the field, and their relevant questions helped to add value to our publication. Kind regards, Dr. Ravi Shrivastava.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, Auctores Publishing LLC, USA Office: +1-(302)-520-2644. I would like to express my sincere appreciation for the efficient and professional handling of my case report by the ‘Journal of Clinical Case Reports and Studies’. The peer review process was not only fast but also highly constructive—the reviewers’ comments were clear, relevant, and greatly helped me improve the quality and clarity of my manuscript. I also received excellent support from the editorial office throughout the process. Communication was smooth and timely, and I felt well guided at every stage, from submission to publication. The overall quality and rigor of the journal are truly commendable. I am pleased to have published my work with Journal of Clinical Case Reports and Studies, and I look forward to future opportunities for collaboration. Sincerely, Aline Tollet, UCLouvain.
Dear Ms. Mayra Duenas, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. “The International Journal of Clinical Case Reports and Reviews represented the “ideal house” to share with the research community a first experience with the use of the Simeox device for speech rehabilitation. High scientific reputation and attractive website communication were first determinants for the selection of this Journal, and the following submission process exceeded expectations: fast but highly professional peer review, great support by the editorial office, elegant graphic layout. Exactly what a dynamic research team - also composed by allied professionals - needs!" From, Chiara Beccaluva, PT - Italy.
Dear Maria Emerson, Editorial Coordinator, we have deeply appreciated the professionalism demonstrated by the International Journal of Clinical Case Reports and Reviews. The reviewers have extensive knowledge of our field and have been very efficient and fast in supporting the process. I am really looking forward to further collaboration. Thanks. Best regards, Dr. Claudio Ligresti
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation. “The peer review process was efficient and constructive, and the editorial office provided excellent communication and support throughout. The journal ensures scientific rigor and high editorial standards, while also offering a smooth and timely publication process. We sincerely appreciate the work of the editorial team in facilitating the dissemination of innovative approaches such as the Bonori Method.” Best regards, Dr. Matteo Bonori.
I recommend without hesitation submitting relevant papers on medical decision making to the International Journal of Clinical Case Reports and Reviews. I am very grateful to the editorial staff. Maria Emerson was a pleasure to communicate with. The time from submission to publication was an extremely short 3 weeks. The editorial staff submitted the paper to three reviewers. Two of the reviewers commented positively on the value of publishing the paper. The editorial staff quickly recognized the third reviewer’s comments as an unjust attempt to reject the paper. I revised the paper as recommended by the first two reviewers.
Dear Maria Emerson, Editorial Coordinator, Journal of Clinical Research and Reports. Thank you for publishing our case report: "Clinical Case of Effective Fetal Stem Cells Treatment in a Patient with Autism Spectrum Disorder" within the "Journal of Clinical Research and Reports" being submitted by the team of EmCell doctors from Kyiv, Ukraine. We much appreciate a professional and transparent peer-review process from Auctores. All research Doctors are so grateful to your Editorial Office and Auctores Publishing support! I amiably wish our article publication maintained a top quality of your International Scientific Journal. My best wishes for a prosperity of the Journal of Clinical Research and Reports. Hope our scientific relationship and cooperation will remain long lasting. Thank you very much indeed. Kind regards, Dr. Andriy Sinelnyk Cell Therapy Center EmCell
Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. It was truly a rewarding experience to work with the journal “Clinical Cardiology and Cardiovascular Interventions”. The peer review process was insightful and encouraging, helping us refine our work to a higher standard. The editorial office offered exceptional support with prompt and thoughtful communication. I highly value the journal’s role in promoting scientific advancement and am honored to be part of it. Best regards, Meng-Jou Lee, MD, Department of Anesthesiology, National Taiwan University Hospital.
Dear Editorial Team, Journal-Clinical Cardiology and Cardiovascular Interventions, “Publishing my article with Clinical Cardiology and Cardiovascular Interventions has been a highly positive experience. The peer-review process was rigorous yet supportive, offering valuable feedback that strengthened my work. The editorial team demonstrated exceptional professionalism, prompt communication, and a genuine commitment to maintaining the highest scientific standards. I am very pleased with the publication quality and proud to be associated with such a reputable journal.” Warm regards, Dr. Mahmoud Kamal Moustafa Ahmed
Dear Maria Emerson, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews’, I appreciate the opportunity to publish my article with your journal. The editorial office provided clear communication during the submission and review process, and I found the overall experience professional and constructive. Best regards, Elena Salvatore.
Dear Mayra Duenas, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews Herewith I confirm an optimal peer review process and a great support of the editorial office of the present journal
Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. I am really grateful for the peers review; their feedback gave me the opportunity to reflect on the message and impact of my work and to ameliorate the article. The editors did a great job in addition by encouraging me to continue with the process of publishing.
Dear Cecilia Lilly, Editorial Coordinator, Endocrinology and Disorders, Thank you so much for your quick response regarding reviewing and all process till publishing our manuscript entitled: Prevalence of Pre-Diabetes and its Associated Risk Factors Among Nile College Students, Sudan. Best regards, Dr Mamoun Magzoub.
International Journal of Clinical Case Reports and Reviews is a high quality journal that has a clear and concise submission process. The peer review process was comprehensive and constructive. Support from the editorial office was excellent, since the administrative staff were responsive. The journal provides a fast and timely publication timeline.
Dear Maria Emerson, Editorial Coordinator of International Journal of Clinical Case Reports and Reviews, What distinguishes International Journal of Clinical Case Report and Review is not only the scientific rigor of its publications, but the intellectual climate in which research is evaluated. The submission process is refreshingly free of unnecessary formal barriers and bureaucratic rituals that often complicate academic publishing without adding real value. The peer-review system is demanding yet constructive, guided by genuine scientific dialogue rather than hierarchical or authoritarian attitudes. Reviewers act as collaborators in improving the manuscript, not as gatekeepers imposing arbitrary standards. This journal offers a rare balance: high methodological standards combined with a respectful, transparent, and supportive editorial approach. In an era where publishing can feel more burdensome than research itself, this platform restores the original purpose of peer review — to refine ideas, not to obstruct them Prof. Perlat Kapisyzi, FCCP PULMONOLOGIST AND THORACIC IMAGING.
Dear Grace Pierce, International Journal of Clinical Case Reports and Reviews I appreciate the opportunity to review for Auctore Journal, as the overall editorial process was smooth, transparent and professionally managed. This journal maintains high scientific standards and ensures timely communications with authors, which is truly commendable. I would like to express my special thanks to editor Grace Pierce for his constant guidance, promt responses, and supportive coordination throughout the review process. I am also greatful to Eleanor Bailey from the finance department for her clear communication and efficient handling of all administrative matters. Overall, my experience with Auctore Journal has been highly positive and rewarding. Best regards, Sabita sinha
Dear Mayra Duenas, Editorial Coordinator of the journal IJCCR, I write here a little on my experience as an author submitting to the International Journal of Clinical Case Reports and Reviews (IJCCR). This was my first submission to IJCCR and my manuscript was inherently an outsider’s effort. It attempted to broadly identify and then make some sense of life’s under-appreciated mysteries. I initially had responded to a request for possible submissions. I then contacted IJCCR with a tentative topic for a manuscript. They quickly got back with an approval for the submission, but with a particular requirement that it be medically relevant. I then put together a manuscript and submitted it. After the usual back-and-forth over forms and formality, the manuscript was sent off for reviews. Within 2 weeks I got back 4 reviews which were both helpful and also surprising. Surprising in that the topic was somewhat foreign to medical literature. My subsequent updates in response to the reviewer comments went smoothly and in short order I had a series of proofs to evaluate. All in all, the whole publication process seemed outstanding. It was both helpful in terms of the paper’s content and also in terms of its efficient and friendly communications. Thank you all very much. Sincerely, Ted Christopher, Rochester, NY.
