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Multiple Sclerosis, Chlamydia and Gut Disbiosis

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Letter To Editor | DOI: https://doi.org/10.31579/2690-1919/208

Multiple Sclerosis, Chlamydia and Gut Disbiosis

  • Jose Artur Medina *

* Fisiopatologia USP, Institute Butantan, SP, Brazil.

*Corresponding Author: Jose Artur Medina, Fisiopatologia USP, Institute Butantan, SP, Brazil.

Citation: Jose A. Medina. (2021). Multiple Sclerosis, Chlamydia and Gut Disbiosis. J Clinical Research and Reports, 9(3); DOI:10.31579/2690-1919/208

Copyright: © 2021, Jose Artur Medina. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: 17 October 2021 | Accepted: 09 November 2021 | Published: 20 November 2021

Keywords: sclerosis; chlamydia; gut disbiosis; probiotics; enterobacterias; herpesvirus; chemotaxis; neurodegeneration; piriformis syndrome; bacterial vaginosis; ureoplasmas

Abstract

I believe that multiple sclerosis progression could be stopped through antibiotics, dewormers, beta glucans and garlic extract and, by far the most difficult, changing the quality of the water ingested, or used for washing salads, in addition to increasing the consumption of probiotics. I believe that MS sclerosis is due to the unfortunate encounter of 3 diseases: intestinal dysbiosis, chlamydia infections and orthopedic problems. However, how would these three diseases cause demyelination of nerve fibers?

Summary

Dear Editor, I believe that multiple sclerosis progression could be stopped through antibiotics, dewormers, beta glucans and garlic extract and, by far the most difficult, changing the quality of the water ingested, or used for washing salads, in addition to increasing the consumption of probiotics. I believe that MS sclerosis is due to the unfortunate encounter of 3 diseases: intestinal dysbiosis, chlamydia infections and orthopedic problems. However, how would these three diseases cause demyelination of nerve fibers? 

1) By the consumption of contaminated water (enterobacterias), which would raise the levels of CD4-Th17 [1-3] that by itself reduce the blood-brain barrier [4-6].

2) A subclinical infection by chlamydia or any other pathogen of the genitourinary tract, via LPS, would stimulate TLR4 and the release of inflammatory mediators, at the expense of the stimulation of DAMPs (beta glucan / hyaluronic acid) that would elevate the levels of antiviral interferon instead of producing more inflammation [7-9].

3) Levels of the endemic herpesvirus would increase, which favors the exteriorization of type 2 MHC complexes as disruptions in signaling created by the own virus [10-12] and, subsequently, systemic Th17 chemotaxis and subsequent IL-17A release and secondary demyelinating neurodegeneration [13-15].

4) Orthopedic problems such as piriformis syndrome [16, 17] or herniated disc [18, 19] favor neurodegeneration and deserve treatment. 

5) Waterborne diseases are epidemiologically important [20, 21], producing reactive arthritis (Reiter's Sd) [22, 23] and making rheumatoid tests positive [24, 25]. 

6) The relationship between lupus and MS could be explained by bacterial vaginosis, which makes the antinuclear factor test positive, when there is a significant presence of ureoplasms and mycoplasmas among the anaerobes that make up bacterial vaginosis, also called Gardnerella [26, 27], lupus would thus be caused by a pelvic inflammatory disease (PID), fibromyalgia would be secondary to the same infection, but without the presence of ureoplasmas and mycoplasmas. Clinical pain would be proportional to the LPS that would migrate through the lymphatic system reaching shoulders and knees as well as neurodegeneration. 

7) Most PIDs are asymptomatic. [28-30]

8) In summary, the progression of MS would be blocked (the infiltration of Th17 and Th1) through the eradication of chlamydia, intestinal dysbiosis and, eventually, by decompression of the affected nerves, in addition to offering garlic extracts that increase interferon [31-33] has the potential to reduce the endemic herpes population in humans.

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