opinion | DOI: https://doi.org/10.31579/2640-1053/212

Malt Lymphoma of the ovary!

  • Hilary Denis Solomons

P.O. Box 64203, Highlands North, 203, South Africa.

*Corresponding Author: Hilary Denis Solomons, P.O. Box 64203, Highlands North, 203, South Africa.

Citation: Hilary Denis Solomons (2024), Malt Lymphoma of the ovary! J. Cancer Research and Cellular Therapeutics, 8(6); DOI:10.31579/2640-1053/212

Copyright: © 2024, Hilary Denis Solomons, this is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Received: 30 September 2024 | Accepted: 08 October 2024 | Published: 15 October 2024

Keywords: maltoma; stomach; esophagogastroduodenoscopy

Abstract

Malt lymphoma of the ovary is rare but does occur.

Also known as maltoma involves the mucosa associated lymphoid tissue. Usually, the ovary or stomach is involved but any mucousal site can be affected.

Summary

Malt lymphoma of the ovary is rare but does occur.

Also known as maltoma involves the mucosa associated lymphoid tissue. Usually, the ovary or stomach is involved but any mucousal site can be affected.

The B cells in the marginal zone are involved resulting in a extranodal marginal zone B cell lymphoma.

Helicobacter pylori is associated with MALT lymphoma (chronic inflammation!)

The initial diagnosis is made on biopsy by means of laparoscopy or esophagogastroduodenoscopy. At the same time, one looks for Helicobacter pylori.

The disease may be associated with autoimmune disorders such as Sjogren’s syndrome or Hashimoto’s thyroiditis.

Thus, the ovary, salivary gland or thyroid may be involved.

If limited to the stomach the disorder may respond just to antibiotics.

However, surgery or chemotherapy may be necessary.

At (11;1809q21; q21) chromosomal translocation, giving rise to a AP12-MLT fusion gene, is predictive of a poor response to eradication therapy.

However, the locus 14q32 may also be involved!

References

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