Research Article | DOI: https://doi.org/10.31579/2768-0487/208
Department of Animal Nutrition and Biochemistry, Gandhi College of Agriculture, Rajasthan India.
*Corresponding Author: Alagbe John Olujimi, Department of Animal Nutrition and Biochemistry, Gandhi College of Agriculture, Rajasthan India
Citation: Alagbe J. Olujimi, (2026), Influence of Megaphrynium macrostarchyum Leaf Extract on the Growth Performance, Hematology, and Serum Parameters of Ross 308 Broilers Reared in Battery Cages, Journal of Clinical and Laboratory Research, 9(3); DOI:10.31579/2768-0487/208
Copyright: © 2026, Alagbe John Olujimi. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Received: 23 May 2026 | Accepted: 03 June 2026 | Published: 16 June 2026
Keywords: megaphrynium macrostarchyum; growth performance; stress leucogram; serum biochemistry; reference range; caged broilers
Background: Intensive broiler production in vertical battery cages often subjects birds to chronic environmental stress, which can compromise growth performance and disrupt metabolic homeostasis. Naturally occurring phytogenic offer a multi-functional alternative to synthetic growth promoters and single-molecule antioxidants. This study investigated the influence of Megaphrynium macrostarchyum ethanolic leaf extract (MME) on the growth performance, hematology, and serum biochemistry parameters of Ross 308 broilers managed in a battery cage system for 42 days. A total of 500-day-old broiler chicks were randomly distributed to 5 dietary treatments in a completely randomized design (5 replicates of 20 birds each). Treatments consisted of: T1 (Negative Control; basal diet), T2 (Positive Control; basal diet + 250 mg synthetic Vitamin C/kg), and T3, T4, and T5 (basal diet supplemented with MME at 200, 400, and 600 mg/kg, respectively). Quantitative profiling confirmed that MME was rich in phenols (250.6 mg/g), flavonoids (187.3 mg/g), steroids (66.35 mg/g), and saponins (25.87 mg/g). At day 42, growth performance was finalized, and blood samples (n=10 per treatment) were collected for haemato-biochemical analysis. Dietary inclusion of MME significantly optimized production performance. Birds in the T3, T4 and T5 groups achieved the highest final body weight and total weight gain, followed in descending linear order by T2, and T1 (P<0.05). Total feed intake was higher in the MME-supplemented groups (T3–T5) than in T1 and T2 (P<0.05). Accordingly, the feed conversion ratio (FCR) was optimized linearly (P<0.05), with the lowest (most efficient) values observed in T3, T4 and T5, intermediate values in T2 and the highest (poorest) values in T1. Crucially, all evaluated hematological parameters (PCV, RBC, Hb, WBC) and serum biochemical profiles (total protein, albumin, globulin, uric acid, creatinine, AST, ALT, and lipid fractions) remained well within the established, healthy physiological reference ranges for healthy broilers. Within these safe baselines, birds fed T3, T4 and T5 exhibited a significant reduction (P<0.05) in the Heterophil-to-Lymphocyte (H: L) ratio compared to T1, alongside lower serum uric acid, AST, ALT, and total cholesterol levels (P<0.05), while serum total protein, globulin and albumin increased (P<0.05).
In conclusion, dietary supplementation of Megaphrynium macrostarchyum leaf extract at 200 to 600 mg/kg maximizes growth kinetics and feed conversion efficiency in caged broilers without inducing systemic toxicity. The extract operates safely within normal physiological limits to alleviate housing stress, enhance nutrient utilization, and optimize lipid metabolism, presenting a superior alternative to synthetic Vitamin C treatment.
The intensive commercial poultry industry continuously seeks natural feed additives to optimize production efficiency while safeguarding animal welfare [1]. In developing tropical countries, the high cost of conventional feed ingredients and the strict global bans on synthetic antibiotic growth promoters (AGPs) have forced a shift toward sustainable phytogenic feed additives (PFAs) [2]. However, rearing fast-growing broiler strains, such as the Ross 308, in vertical battery cage systems often introduces chronic micro-environmental stressors [3]. These housing stressors trigger the overproduction of reactive oxygen species (ROS), leading to systemic oxidative stress, sub-clinical gut inflammation, and elevated metabolic costs. When birds must constantly divert dietary nutrients toward cellular repair and immune maintenance, their genetic potential for muscle accretion is heavily compromised, manifesting as poor growth rates and inefficient feed conversion [4].
While synthetic antioxidants and single-molecule isolates like ascorbic acid (Vitamin C) have traditionally been deployed to mitigate these environmental challenges, their single-pathway action fails to address the multi-organ demands of the bird's digestive and metabolic systems [5, 8]. Consequently, researchers have turned to underutilized tropical flora, which possess complex, multi-functional secondary metabolite profiles [4, 16]. Recent studies evaluating similar phytogenic matrices, such as extracts from Moringa oleifera, Clausen anisata, Daniellia oliveri, Polyalthia longifolia and Newbouldia laevis amongst others have reported significant improvements in broiler growth kinetics, enhanced cellular integrity, and stabilized white blood cell profiles [5, 6, 7, 8, 18]. These botanical additives operate through an integrated mechanism: their dense phenolic and flavonoid fractions act as high-efficiency radical scavengers, while their saponins and alkaloids stabilize the intestinal microbiome, thereby reducing sub-clinical pathogenic loads and favoring optimal nutrient uptake [9, 10, 11, 12, 17].
Despite the documented success of several tropical plants, the nutritional and therapeutic potentials of Megaphrynium macrostarchyum—a robust, perennial herb widely distributed across the West African rainforest belt—remain largely underutilized and undocumented in broiler nutrition. Known for its resilient bioactive profile, M. macrostarchyum leaves contain a rich matrix of phenols, flavonoids, steroids, saponins, and alkaloids that could serve as an excellent natural growth promoter and adaptogen [13, 14]. While its traditional use in food packaging hints at inherent antimicrobial properties, there is a distinct lack of rigorous scientific literature mapping out how its ethanolic extract modulates the complex physiological pathways of intensively housed livestock [14, 16]. Investigating this plant could uncover a valuable, locally available resource to help reduce the poultry industry's reliance on imported synthetic additives [15].
Therefore, this study was designed to evaluate the influence of Megaphrynium macrostarchyum leaf extract (MME) on the growth performance, hematology, and serum parameters of Ross 308 broilers reared in battery cages. By analyzing these specific blood and biochemical profiles alongside standard performance metrics, this research aims to establish the definitive physiological safety and efficacy of MME. Ultimately, this study provides a clear justification for utilizing graded dietary inclusions of this extract as a safe, practical, and highly efficient alternative to synthetic Vitamin C monotherapy in commercial poultry production.
Experimental Location and Ethical Approval
The 42-day feeding trial was conducted at the Poultry Research Unit of the Gandhi College of Agriculture, Rajasthan, India. All experimental protocols, animal handling procedures, and welfare management steps were reviewed and approved by the Institutional Animal Ethics Committee (IAEC) prior to commencing the study.
Collection, authentication and processing of Megaphrynium macrostarchyum leaves
Fresh, mature, disease-free leaves of Megaphrynium macrostarchyum were harvested from multiple parent plants at the institutional experimental sites of the Gandhi College of Agriculture, Rajasthan, using sterile stainless-steel shears, and transported at 4°C in a chilled, insulated container. Representative botanical specimens with intact leaf blades, petioles, and associated reproductive structures were pressed, dried, and submitted to the institutional herbarium for taxonomic authentication a reference voucher index number HJ/0922C/225N was issued. The remaining leaves were rinsed with running tap water followed by double-distilled water, cut into 1×1 cm fragments, and flash-frozen in liquid nitrogen before being lyophilized in a Laconic Free Zone 4.5 Liter Freeze Dryer (Model: 7420020) at −84∘C and 0.045 mbar for 48 to 72 hours. The crisp structural matrix was pulverized using an IKA A11 Basic Analytical Mill through a 0.5 mm screen, and 100 g of the resulting powder was subjected to cold maceration in 1000 mL of 70% v/v aqueous ethanol under dark conditions on an IKA KS 4000 ic Control Incubator Shaker at 150 rpm for 48 hours at 25∘C. The crude mixture was vacuum-filtered through Whatman No. 1 filter paper and concentrated using a Buchi Rotavapor R-300 Rotary Evaporator System (equipped with a Heating Bath B-305 and Vacuum Pump V-300) at 40∘C and 100 mbar before a final 24-hour freeze-drying cycle yielded the pure, moisture-free extract powder stored at −20∘C.
Phytochemical Quantification
Quantitative profiling of the bioactive secondary metabolites was executed using high-throughput microtiter assays, gas chromatography-mass spectrometry (GC-MS), and high-performance liquid chromatography (HPLC). Total phenolic and flavonoid contents were measured via the Folin-Ciocalteu and aluminum chloride colorimetric protocols using a Thermo Scientific Multiskan Sky-high Microplate Spectrophotometer (Model: 51112000) at target absorbances of 765 nm and 415 nm, respectively, against Sigma-Aldrich reference calibration curves. Volatile fractions and lipophilic compounds were resolved using an Agilent 8890 GC System integrated with an Agilent 5977B GC/MSD and a 7693A Autoinjector, utilizing an Agilent J&W HP-5MS Ultra Inert Capillary Column (30 m×0.25 mm×0.25 μm). Exactly 1.0 μL of extract was injected at a 1:50 split ratio at an inlet temperature of 250∘C under a constant helium flow of 1.0 mL/min and an oven profile rising from 60∘C to 280∘C (electron ionization at 70 eV, scan range 35 to 500 m/z), with peaks identified against the NIST 20 Mass Spectral Library Database. Non-volatile polyphenolic markers were mapped via a Waters Alliance e2695 Separation Module HPLC System linked to a Waters 2998 Photodiode Array Detector using a Phenomenex Luna C18(2) Column (250 × 4.6 mm,5 μm), operating a 1.0 mL/min gradient elution of 0.1% formic acid in water (Solvent A) and 100?etonitrile (Solvent B) at 30∘C with dynamic diode array multi-wavelength tracking at 280 nm and 360 nm.
Birds, Housing, and Bio-Security Operations
A total of 500 day-old straight-run broiler chicks (Ross 308 strain) were purchased from a commercial hatchery. The birds were housed in a clean, environmentally regulated poultry house equipped with 3-tier battery cage units. Each cage tier provided a floor area configuration that complied with international standard animal density guidelines. Two weeks before the chicks arrived, the entire poultry house, including the battery cages, linear galvanized feeders, and nipple drinkers, was thoroughly cleaned and disinfected using a broad-spectrum virucidal and bactericidal solution. The temperature inside the house was initially set to 33∘C for the first week and gradually reduced by 2∘C each week until it reached a baseline of 23∘C to 24∘C, where it remained for the rest of the trial. The lighting schedule provided 23 hours of light and 1 hour of darkness daily during the first and final weeks, with a 20-hour light and 4-hour darkness profile used during the intermediate growth phase. All birds were vaccinated against Newcastle Disease (ND) and Infectious Bursal Disease (IBD) following standard local vaccination timelines.
Diet Formulation and Experimental Treatments
The feeding program was divided into two phases: a starter diet fed from day 0 to 21, and a finisher diet fed from day 22 to 42. Both basal diets were formulated using corn and soybean meal as the primary ingredients to meet or exceed the nutrient requirements set by the National Research Council [19]. Feed and fresh drinking water were provided ad libitum throughout the 42-day trial.
The 500-day-old chicks were randomly assigned to one of 5 distinct dietary treatments. Each treatment included 5 replicates, with 20 birds per replicate cage unit, arranged in a completely randomized design (CRD). The groups were defined as follows:
Treatment 1 (T1, Negative Control): Received the basal diet alone, with no additives.
Treatment 2 (T2, Positive Control): Received the basal diet supplemented with 250 mg of synthetic Vitamin C (ascorbic acid) per kilogram of feed.
Treatment 3 (T3): Received the basal diet supplemented with 200 mg of MME powder per kilogram of feed.
Treatment 4 (T4): Received the basal diet supplemented with 400 mg of MME powder per kilogram of feed.
Treatment 5 (T5): Received the basal diet supplemented with 600 mg of MME powder per kilogram of feed.
To ensure uniform distribution, the Vitamin C and MME powders were first thoroughly mixed into small batches of feed to create a concentrated premix, which was then evenly incorporated into the main bulk diets.
Performance Data Collection
The birds were weighed individually at the start of the trial (day 0), at the end of the starter phase (day 21), and at the conclusion of the experiment (day 42). The Final Body Weight (FBW) and Average Daily Gain (ADG) were calculated for each replicate group.
Feed consumption was tracked weekly for each replicate cage by measuring the total amount of feed provided minus the weight of any leftover feed. Total Feed Intake (FI) was calculated for both the starter and finisher phases.
Feed Conversion Efficiency: Mortality was recorded daily to adjust the feed efficiency calculations. The Feed Conversion Ratio (FCR) for each replicate was calculated at day 42 using the standard formula:
FCR=Total Live Weight Gain of Surviving Birds per Replicate Group (g) / Total Feed Intake per Replicate Group (g)
Blood collection and processing
At the conclusion of the 42-day trial, 10 birds were randomly selected per treatment (2 birds per replicate) for blood sampling. Approximately 5 mL of whole blood was drawn from the bronchial vein of each bird using sterile 23-gauge needles attached to 5 mL disposable syringes. For hematological analysis, a 2 mL portion of the drawn blood was immediately transferred into plastic tubes containing Ethylenediaminetetraacetic acid (EDTA-K3 tubes, 2.0 mL capacity, BD Vacutainer) to prevent coagulation. The remaining 3 mL of blood was discharged into plain non-anticoagulant vacuum tubes containing a clot activator and gel separator (BD Vacutainer SST II Advance, 5.0 mL volume) and allowed to clot at room temperature (25∘C) for 30 minutes. To separate the serum, these gel tubes were centrifuged using a refrigerated benchtop centrifuge (Eppendorf Centrifuge 5810 R, configured with an S-4-104 swinging-bucket rotor) operated at 3000 rpm (1811×g) at a temperature controlled at 4∘C for exactly 15 minutes. The resulting clear, unhemolyzed serum supernatant was carefully aspirated using a variable-volume micropipette (Eppendorf Research Plus, 100 to 1000 μL range) and divided into sterile 1.5 mL microcentrifuge aliquots before being deep-frozen and stored at −80∘C in an ultra-low temperature freezer (Thermo Scientific Revco ExF Series, Model: ExF24086V) until final colorimetric and enzymatic analysis.
All collected data were subjected to a One-Way Analysis of Variance (ANOVA) using the General Linear Model (GLM) procedure in SPSS Statistics Software (Version 26.0). The mathematical model used for the analysis was:
Yij=μ+Ti+eij
Where Yij is the individual observation, μ is the overall mean, Ti represents the fixed effect of the dietary treatment, and eij is the random error component.
Results
Phytochemical composition of Megaphrynium macrostarchyum leaf extract showed that it contains phenols in higher concentration of 250.6 mg/g while alkaloids (12.60 mg/g) had the lowest concentration. Phytochemicals showed this rank order: phenols > flavonoids > tannins > steroids > saponins > alkaloids (Table 2).
Daily weight gain and daily feed intake was more (p<0>
Whereas pack cell volume, red blood cell, hemoglobin concentration, and lymphocytes were higher (p<0>0.05) among the diets (Table 4).
Except for total protein, albumin, globulin, uric acid, cholesterol, triglycerides, low density lipoprotein, aspartate aminotransferase and alanine aminotransferase concentrations which were affected (p<0> 0.05) difference (Table 5).
| Starter phase (0-21 d) | Finisher phase (22-42d) | |
| Ingredients | Quantity | Quantity |
| Maize | 51.00 | 55.00 |
| Wheat bran | 2.00 | 4.39 |
| Soyabean meal | 35.05 | 29.05 |
| Fish meal | 4.89 | 3.00 |
| Limestone | 2.00 | 2.50 |
| Dicalcium Phosphate | 4.00 | 5.00 |
| DL-Methionine | 0.25 | 0.25 |
| L-Lysine HCl | 0.25 | 0.25 |
| Min-Vit Premix | 0.25 | 0.25 |
| Salt | 0.20 | 0.20 |
| Toxin binder | 0.11 | 0.11 |
| Total | 100.0 | 100.0 |
| Analyzed values | ||
| Dry matter | 87.17 | 88.03 |
| Crude protein | 23.12 | 21.06 |
| Crude fiber | 3.88 | 4.01 |
| Ether extract | 4.08 | 4.21 |
| Calcium | 1.17 | 1.19 |
| Phosphorus | 0.56 | 0.58 |
| ME (kcal/kg) | 2908.2 | 3016.5 |
Table 1: Ingredient and Chemical composition of experimental diet (% DM)
Starter Vitamin-Mineral Premix: (Retinol) based on 2.5 kg/ton (Thiamine, 2000 mg, riboflavin, 7000 mg, pyridoxine, 5000 mg, cyanocobalamin, 1700 mg, niacin, 30,000 mg, D-pantothenate, 10,000 mg, folic acid, 800 mg, biotin, 2000 mg, Retinyl acetate, 12,000 iu., cholecalciferol, 2,400,000 iu., tocopherol acetate, 35,000 iu., menadione, 4,000 mg, ascorbic acid, 60,000 mg, manganese, nil, iron, 70,200 mg, zinc, nil, copper, nil, cobalt, 200 mg, iodine, 400 mg, selenium, 80 mg, choline chloride, 500,000.
| Phyto-compounds | Composition (mg/g) |
| Total phenols | 250.6 |
| Flavonoids | 187.3 |
| Tannins | 86.10 |
| Alkaloids | 12.60 |
| Saponins | 25.87 |
| Steroids | 66.35 |
Table 2: Phytochemical composition of Megaphrynium macrostarchyum Leaf Extract
Note: a-d Means within the same row with different superscripts differ significantly (P<0>
Table 3: Influence of Megaphrynium macrostarchyum Leaf Extract on the Growth Performance of Ross 308 Broilers
Note: a-d Means within the same row with different superscripts differ significantly (P<0>
Table 4: Influence of Megaphrynium macrostarchyum Leaf Extract on the Serum Biochemical Indices of Ross 308 Broilers
Table 5: Influence of Megaphrynium macrostarchyum Leaf Extract on the Hematological Parameters of Ross 308 Broilers
Note: a-d Means within the same row with different superscripts differ significantly (P<0 xss=removed xss=removed xss=removed xss=removed>
The marked variation in weight gain across the treatments highlights the significant growth-promoting and metabolic advantages of Megaphrynium macrostarchyum ethanolic extract (MME) over both the unsupplemented negative control (T1) and treatment 2 (Vitamin C). Birds maintained on the basal diet alone (T1) exhibited the lowest weight gain, a reaction directly tied to the physiological constraints of intensive battery cage housing without any dietary antioxidant or immunomodulatory support, these birds succumb to chronic micro-environmental confinement stress [20]. This stress elevates systemic corticosterone levels, triggering lipid peroxidation and micro-inflammation within the intestinal mucosa. Consequently, a substantial portion of their dietary energy and amino acids is diverted away from muscle tissue synthesis to fuel cellular repair and immune maintenance [21]. While the inclusion of 250 mg/kg of Vitamin C in T2 provided intermediate relief by acting as a direct, targeted free-radical scavenger, its single-molecule nature lacks the multi-pathway functionality necessary to fully maximize growth kinetics. Vitamin C assists in lowering systemic oxidative stress, but it does not actively stimulate appetite or modulate gut architecture, which explains why its performance remained lower than the extract-supplemented groups [22]. In contrast, the superior weight gain observed in the MME-supplemented group (T3–T5) demonstrates the power of a complex, multi-tiered phytogenic matrix [22]. The extract's rich combination of total phenols (250.6 mg/g) and flavonoids (187.3 mg/g) functions as an integrated, high-efficiency antioxidant shield that neutralizes reactive oxygen species (ROS) far more effectively than Vitamin C alone, allowing maximum sparing of nutrients for skeletal muscle deposition. Simultaneously, the extract's steroidal fractions (66.35 mg/g) act as natural anabolic modulators, enhancing intracellular protein synthesis, nitrogen retention, and breast muscle development [23]. This metabolic advantage is further amplified by the extract's saponins (25.87 mg/g) and alkaloids (12.60 mg/g), which exert strong abiotic control over the gut, suppressing sub-clinical pathogens to foster taller, healthier intestinal villi. This optimized gut architecture increases nutrient absorption capacity, ensuring that the higher feed intake seen in these groups is converted into live weight gain with peak biological efficiency [24]. This result is in agreement with the reports of [25, 26, 27] who recorded a higher daily body weight and feed intake of birds fed diet supplemented with different levels of essential oils.
Hematology serves as a direct indicator of the birds' immune status, oxygen-carrying capacity, and physiological stress levels [23]. All the values recorded in this study was within safe baselines for healthy birds [28, 29]. PCV, Hb and red blood cell values was within 28.00 – 36.00 %, 8.91 – 16.00 g/dL and 1.93 – 5.00 (1012/L) respectively cited by [30]. Though, PCV, Hb and red blood cells of birds fed diet supplemented with MME (T3-T5) had higher values relative to T1 and T2. This result suggests oxygen and iron sufficiency in the blood [31]. The powerful antioxidant network in MME shields the lipid bilayers of red blood cells from oxidative damage, extending their lifespan [26]. Furthermore, the steroidal fractions (66.35 mg/g) can stimulate erythropoiesis (red blood cell production) in the bone marrow, optimizing oxygen transport to rapidly developing breast and thigh muscles [21]. White blood cell and lymphocyte count reported in this experiment was within 12.00 – 25.00 (109/L) and 40.00 – 80.00 % referenced by [24]. Birds in T1 exhibits a significantly elevated heterophil-to-lymphocyte (H: L) ratio relative to other groups. Chronic confinement stress triggers the hypothalamic-pituitary-adrenal (HPA) axis to secrete corticosterone, causing heterophilia (increased stress white blood cells) and lymphopenia (decreased immune white blood cells) [25]. In groups T3 (200 mg/kg), T4 (400 mg/kg) and T5 (600 mg/kg), the H:L ratio drops significantly, returning to a normal baseline [26]. The high phenolic (250.6 mg/g) and flavonoid (187.3 mg/g) content suppresses the systemic cortisol/corticosterone spike by neutralizing circulating free radicals, preventing the typical stress-induced shift in white blood cell populations [22].
Serum biochemical parameters reflect liver integrity, kidney function, lipid transport, and protein metabolism [8] Serum total protein, globulin and albumin levels were significantly higher in T3, T4 and T5 compared to T1. This enhancement is driven by the presence of phytochemicals in MME. For instance, saponins (25.87 mg/g) and alkaloids (12.60 mg/g) reduce gut pathogen load, allowing for robust intestinal villi and superior absorption of amino acids [32, 33]. Similarly, the presence of steroids in MME (66.35 mg/g) act as natural anabolic modulators, promoting hepatic protein synthesis and efficient nitrogen retention [34]. High serum globulin levels in T3–T5 also indicate enhanced humoral immunity due to active flavonoid-stimulated antibody production [1, 4]. T1 birds often experience a sub-clinical leakage of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) enzymes into the bloodstream due to stress-induced hepatic lipid peroxidation. In the MME-supplemented groups (T3–T5), serum AST and ALT levels drop and stabilize within tight, healthy baselines. This confirms that the extract is completely non-toxic and hepatoprotective; its polyphenols shield liver cell membranes (hepatocytes) from structural breakdown [31]. Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) values were within the normal range 98.1 – 200 IU/L and 12.00 – 30.00 IU/L cited by [27]. Uric acid and creatinine levels was lower in T3, T4 and T5 compared to T1. In poultry, high serum uric acid indicates poor utilization or wasting of dietary protein [7]. Because the FCR was optimized in the T3 - T5 groups, the lower serum uric acid levels confirm that amino acids from the starter and finisher diets were efficiently integrated into skeletal muscle tissue rather than being broken down and excreted as waste [10, 36]. Normal, low creatinine levels across all groups confirm that the extract does not cause renal toxicity [22, 32]. Total cholesterol, triglycerides, and low-density lipoproteins (LDL) follow this trend T1>T2>T3>T4>T5. This suggests hypolipidemic effect which is primarily driven by the saponins (25.87 mg/g) present in M. macrostarchyum [33, 34]. Saponins bind readily with cholesterol and bile acids within the intestinal lumen, forming insoluble complexes that prevent reabsorption through the enterohepatic circulation [7, 35]. To replace these lost bile acids, the liver must convert circulating serum cholesterol into bile, effectively lowering systemic total cholesterol, triglycerides, and LDL levels while keeping beneficial high-density lipoproteins (HDL) intact [8]. The HDL reported in this study aligns with 58.00 – 71.00 mg/dL recorded by [7] when birds were fed diet supplemented with Carica papaya essential oil.
The 42-day feeding trial demonstrates that Megaphrynium macrostarchyum ethanolic leaf extract (MME) functions as a highly effective, multi-functional phytogenic feed additive for Ross 308 broiler chickens managed in intensive battery cage systems. The experimental data reveals that the extract comprehensively improves production kinetics, stress tolerance, and metabolic health. Incorporating MME at thresholds between 200 mg/kg and 600 mg/kg (Treatments T3, T4 and T5) yields the most significant physiological benefits. At these inclusion rates, the extract's rich matrix of specialized secondary metabolites—specifically its phenols, flavonoids, steroids, saponins, and alkaloids—works synergistically to outperform both the unsupplemented basal diet and synthetic Vitamin C group. The growth performance data and blood profiling results provide clear evidence of how MME supports broiler development: The higher final body weights and optimized feed conversion ratios (FCR) in the T3 - T5 groups are directly supported by improved nutrient absorption and tissue deposition. The extract's appetite-stimulating properties safely drove higher feed intake, while its anabolic steroidal fractions (66.35 mg/g) supported nitrogen retention and muscle building. The significant decrease in the Heterophil-to-Lymphocyte (H: L) ratio in the extract-supplemented groups proves that MME successfully mitigates cage-induced environmental stress. The high concentration of polyphenols (250.6 mg/g total phenols; 187.3 mg/g flavonoids) served as an efficient free-radical scavenging system. This minimized lipid peroxidation, preserved red blood cell structural integrity (as shown by elevated PCV and hemoglobin levels), and prevented the birds from wasting dietary energy on cellular repair. Serum biochemistry confirmed that the extract significantly boosts protein metabolism and liver function. Higher total protein and albumin levels, paired with a distinct drop in serum uric acid, show that these birds utilized amino acids with high metabolic efficiency.
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Dear Mayra Duenas, Editorial Coordinator of the journal IJCCR, I write here a little on my experience as an author submitting to the International Journal of Clinical Case Reports and Reviews (IJCCR). This was my first submission to IJCCR and my manuscript was inherently an outsider’s effort. It attempted to broadly identify and then make some sense of life’s under-appreciated mysteries. I initially had responded to a request for possible submissions. I then contacted IJCCR with a tentative topic for a manuscript. They quickly got back with an approval for the submission, but with a particular requirement that it be medically relevant. I then put together a manuscript and submitted it. After the usual back-and-forth over forms and formality, the manuscript was sent off for reviews. Within 2 weeks I got back 4 reviews which were both helpful and also surprising. Surprising in that the topic was somewhat foreign to medical literature. My subsequent updates in response to the reviewer comments went smoothly and in short order I had a series of proofs to evaluate. All in all, the whole publication process seemed outstanding. It was both helpful in terms of the paper’s content and also in terms of its efficient and friendly communications. Thank you all very much. Sincerely, Ted Christopher, Rochester, NY.
International Journal of Clinical Case Reports and Reviews is a high quality journal that has a clear and concise submission process. The peer review process was comprehensive and constructive. Support from the editorial office was excellent, since the administrative staff were responsive. The journal provides a fast and timely publication timeline.
Dear Cecilia Lilly, Editorial Coordinator, Endocrinology and Disorders, Thank you so much for your quick response regarding reviewing and all process till publishing our manuscript entitled: Prevalence of Pre-Diabetes and its Associated Risk Factors Among Nile College Students, Sudan. Best regards, Dr Mamoun Magzoub.
Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. I am really grateful for the peers review; their feedback gave me the opportunity to reflect on the message and impact of my work and to ameliorate the article. The editors did a great job in addition by encouraging me to continue with the process of publishing.
Dear Mayra Duenas, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews Herewith I confirm an optimal peer review process and a great support of the editorial office of the present journal
Dear Maria Emerson, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews’, I appreciate the opportunity to publish my article with your journal. The editorial office provided clear communication during the submission and review process, and I found the overall experience professional and constructive. Best regards, Elena Salvatore.
Dear Editorial Team, Journal-Clinical Cardiology and Cardiovascular Interventions, “Publishing my article with Clinical Cardiology and Cardiovascular Interventions has been a highly positive experience. The peer-review process was rigorous yet supportive, offering valuable feedback that strengthened my work. The editorial team demonstrated exceptional professionalism, prompt communication, and a genuine commitment to maintaining the highest scientific standards. I am very pleased with the publication quality and proud to be associated with such a reputable journal.” Warm regards, Dr. Mahmoud Kamal Moustafa Ahmed
Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. It was truly a rewarding experience to work with the journal “Clinical Cardiology and Cardiovascular Interventions”. The peer review process was insightful and encouraging, helping us refine our work to a higher standard. The editorial office offered exceptional support with prompt and thoughtful communication. I highly value the journal’s role in promoting scientific advancement and am honored to be part of it. Best regards, Meng-Jou Lee, MD, Department of Anesthesiology, National Taiwan University Hospital.
Dear Maria Emerson, Editorial Coordinator, Journal of Clinical Research and Reports. Thank you for publishing our case report: "Clinical Case of Effective Fetal Stem Cells Treatment in a Patient with Autism Spectrum Disorder" within the "Journal of Clinical Research and Reports" being submitted by the team of EmCell doctors from Kyiv, Ukraine. We much appreciate a professional and transparent peer-review process from Auctores. All research Doctors are so grateful to your Editorial Office and Auctores Publishing support! I amiably wish our article publication maintained a top quality of your International Scientific Journal. My best wishes for a prosperity of the Journal of Clinical Research and Reports. Hope our scientific relationship and cooperation will remain long lasting. Thank you very much indeed. Kind regards, Dr. Andriy Sinelnyk Cell Therapy Center EmCell
I recommend without hesitation submitting relevant papers on medical decision making to the International Journal of Clinical Case Reports and Reviews. I am very grateful to the editorial staff. Maria Emerson was a pleasure to communicate with. The time from submission to publication was an extremely short 3 weeks. The editorial staff submitted the paper to three reviewers. Two of the reviewers commented positively on the value of publishing the paper. The editorial staff quickly recognized the third reviewer’s comments as an unjust attempt to reject the paper. I revised the paper as recommended by the first two reviewers.
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation. “The peer review process was efficient and constructive, and the editorial office provided excellent communication and support throughout. The journal ensures scientific rigor and high editorial standards, while also offering a smooth and timely publication process. We sincerely appreciate the work of the editorial team in facilitating the dissemination of innovative approaches such as the Bonori Method.” Best regards, Dr. Matteo Bonori.
Dear Maria Emerson, Editorial Coordinator, we have deeply appreciated the professionalism demonstrated by the International Journal of Clinical Case Reports and Reviews. The reviewers have extensive knowledge of our field and have been very efficient and fast in supporting the process. I am really looking forward to further collaboration. Thanks. Best regards, Dr. Claudio Ligresti
Dear Ms. Mayra Duenas, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. “The International Journal of Clinical Case Reports and Reviews represented the “ideal house” to share with the research community a first experience with the use of the Simeox device for speech rehabilitation. High scientific reputation and attractive website communication were first determinants for the selection of this Journal, and the following submission process exceeded expectations: fast but highly professional peer review, great support by the editorial office, elegant graphic layout. Exactly what a dynamic research team - also composed by allied professionals - needs!" From, Chiara Beccaluva, PT - Italy.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, Auctores Publishing LLC, USA Office: +1-(302)-520-2644. I would like to express my sincere appreciation for the efficient and professional handling of my case report by the ‘Journal of Clinical Case Reports and Studies’. The peer review process was not only fast but also highly constructive—the reviewers’ comments were clear, relevant, and greatly helped me improve the quality and clarity of my manuscript. I also received excellent support from the editorial office throughout the process. Communication was smooth and timely, and I felt well guided at every stage, from submission to publication. The overall quality and rigor of the journal are truly commendable. I am pleased to have published my work with Journal of Clinical Case Reports and Studies, and I look forward to future opportunities for collaboration. Sincerely, Aline Tollet, UCLouvain.
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation, Auctores Publishing LLC, We would like to thank the editorial team for the smooth and high-quality communication leading up to the publication of our article in the Journal of Neurodegeneration and Neurorehabilitation. The reviewers have extensive knowledge in the field, and their relevant questions helped to add value to our publication. Kind regards, Dr. Ravi Shrivastava.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, I would like to express my deep admiration for the exceptional professionalism demonstrated by your journal. I am thoroughly impressed by the speed of the editorial process, the substantive and insightful reviews, and the meticulous preparation of the manuscript for publication. Additionally, I greatly appreciate the courteous and immediate responses from your editorial office to all my inquiries. Best Regards, Dariusz Ziora
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. Thank you for publishing our article, Exploring Clozapine's Efficacy in Managing Aggression: A Multiple Single-Case Study in Forensic Psychiatry in the international journal of clinical case reports and reviews. We found the peer review process very professional and efficient. The comments were constructive, and the whole process was efficient. On behalf of the co-authors, I would like to thank you for publishing this article. With regards, Dr. Jelle R. Lettinga.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. The peer review process of the journal of Clinical Cardiology and Cardiovascular Interventions was excellent and fast, as was the support of the editorial office and the quality of the journal. Kind regards Walter F. Riesen Prof. Dr. Dr. h.c. Walter F. Riesen.
Dear Erin Aust, Editorial Coordinator, Journal of General Medicine and Clinical Practice. We are pleased to share our experience with the “Journal of General Medicine and Clinical Practice”, following the successful publication of our article. The peer review process was thorough and constructive, helping to improve the clarity and quality of the manuscript. We are especially thankful to Ms. Erin Aust, the Editorial Coordinator, for her prompt communication and continuous support throughout the process. Her professionalism ensured a smooth and efficient publication experience. The journal upholds high editorial standards, and we highly recommend it to fellow researchers seeking a credible platform for their work. Best wishes By, Dr. Rakhi Mishra.
Dr Hala Al Shaikh This is to acknowledge that the peer review process for the article ’ A Novel Gnrh1 Gene Mutation in Four Omani Male Siblings, Presentation and Management ’ sent to the International Journal of Clinical Case Reports and Reviews was quick and smooth. The editorial office was prompt with easy communication.
Dear Agrippa Hilda, Editorial Coordinator, Journal of Neuroscience and Neurological Surgery. The entire process including article submission, review, revision, and publication was extremely easy. The journal editor was prompt and helpful, and the reviewers contributed to the quality of the paper. Thank you so much! Eric Nussbaum, MD
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. Many thanks for publishing this manuscript after I lost confidence the editors were most helpful, more than other journals Best wishes from, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Maria Emerson, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. I am delighted to have published our manuscript, "Acute Colonic Pseudo-Obstruction (ACPO): A rare but serious complication following caesarean section." I want to thank the editorial team, especially Maria Emerson, for their prompt review of the manuscript, quick responses to queries, and overall support. Yours sincerely Dr. Victor Olagundoye.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. I appreciate the journal (JCCI) editorial office support, the entire team leads were always ready to help, not only on technical front but also on thorough process. Also, I should thank dear reviewers’ attention to detail and creative approach to teach me and bring new insights by their comments. Surely, more discussions and introduction of other hemodynamic devices would provide better prevention and management of shock states. Your efforts and dedication in presenting educational materials in this journal are commendable. Best wishes from, Farahnaz Fallahian.
Dear Ashley Rosa, Editorial Coordinator of the journal - Psychology and Mental Health Care. " The process of obtaining publication of my article in the Psychology and Mental Health Journal was positive in all areas. The peer review process resulted in a number of valuable comments, the editorial process was collaborative and timely, and the quality of this journal has been quickly noticed, resulting in alternative journals contacting me to publish with them." Warm regards, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.
To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina
My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.
We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.
Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.
I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.
"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".
To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.
I would like to express my sincere gratitude for the support and efficiency provided by the editorial office throughout the publication process of my article, “Delayed Vulvar Metastases from Rectal Carcinoma: A Case Report.” I greatly appreciate the assistance and guidance I received from your team, which made the entire process smooth and efficient. The peer review process was thorough and constructive, contributing to the overall quality of the final article. I am very grateful for the high level of professionalism and commitment shown by the editorial staff, and I look forward to maintaining a long-term collaboration with the International Journal of Clinical Case Reports and Reviews.
Dear Agrippa Hilda- Editorial Coordinator of Journal of Neuroscience and Neurological Surgery, "The peer review process was very quick and of high quality, which can also be seen in the articles in the journal. The collaboration with the editorial office was very good."
I would like to offer my testimony in the support. I have received through the peer review process and support the editorial office where they are to support young authors like me, encourage them to publish their work in your esteemed journals, and globalize and share knowledge globally. I really appreciate your journal, peer review, and editorial office.
My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.
My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.
My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.
The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.
Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.
Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.
I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.
I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.
I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.
We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.
I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.
"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".
I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!
Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.
Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.
International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.
Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.
As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.
Dear Hao Jiang, to Journal of Nutrition and Food Processing We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.
This is an acknowledgment for peer reviewers, editorial board of Journal of Clinical Research and Reports. They show a lot of consideration for us as publishers for our research article “Evaluation of the different factors associated with side effects of COVID-19 vaccination on medical students, Mutah university, Al-Karak, Jordan”, in a very professional and easy way. This journal is one of outstanding medical journal.
Dr. Bernard Terkimbi Utoo, I am happy to publish my scientific work in Journal of Women Health Care and Issues (JWHCI). The manuscript submission was seamless and peer review process was top notch. I was amazed that 4 reviewers worked on the manuscript which made it a highly technical, standard and excellent quality paper. I appreciate the format and consideration for the APC as well as the speed of publication. It is my pleasure to continue with this scientific relationship with the esteem JWHCI.
Testimony of Journal of Clinical Otorhinolaryngology: work with your Reviews has been a educational and constructive experience. The editorial office were very helpful and supportive. It was a pleasure to contribute to your Journal.
Thank you most sincerely, with regard to the support you have given in relation to the reviewing process and the processing of my article entitled "Large Cell Neuroendocrine Carcinoma of The Prostate Gland: A Review and Update" for publication in your esteemed Journal, Journal of Cancer Research and Cellular Therapeutics". The editorial team has been very supportive.
Dr. Katarzyna Byczkowska My testimonial covering: "The peer review process is quick and effective. The support from the editorial office is very professional and friendly. Quality of the Clinical Cardiology and Cardiovascular Interventions is scientific and publishes ground-breaking research on cardiology that is useful for other professionals in the field.
Journal of Neuroscience and Neurological Surgery. I had the experience of publishing a research article recently. The whole process was simple from submission to publication. The reviewers made specific and valuable recommendations and corrections that improved the quality of my publication. I strongly recommend this Journal.
The peer-review process which consisted high quality queries on the paper. I did answer six reviewers’ questions and comments before the paper was accepted. The support from the editorial office is excellent.
We would like to thank the Journal of Thoracic Disease and Cardiothoracic Surgery because of the services they provided us for our articles. The peer-review process was done in a very excellent time manner, and the opinions of the reviewers helped us to improve our manuscript further. The editorial office had an outstanding correspondence with us and guided us in many ways. During a hard time of the pandemic that is affecting every one of us tremendously, the editorial office helped us make everything easier for publishing scientific work. Hope for a more scientific relationship with your Journal.
Journal of Clinical Research and Reports I would be very delighted to submit my testimonial regarding the reviewer board and the editorial office. The reviewer board were accurate and helpful regarding any modifications for my manuscript. And the editorial office were very helpful and supportive in contacting and monitoring with any update and offering help. It was my pleasure to contribute with your promising Journal and I am looking forward for more collaboration.
Journal of Women Health Care and Issues By the present mail, I want to say thank to you and tour colleagues for facilitating my published article. Specially thank you for the peer review process, support from the editorial office. I appreciate positively the quality of your journal.
Journal of Clinical Cardiology and Cardiovascular Intervention The submission and review process was adequate. However I think that the publication total value should have been enlightened in early fases. Thank you for all.
Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. Auctoresonline publishing platform can be used to facilitate of optimal client-based services and should be added to health care professionals' repertoire of evidence-based health care resources.
