AUCTORES
Globalize your Research
Research Article | DOI: https://doi.org/10.31579/2641-0419/052
1 Cardiology Department of Grand Yoff General Hospital, Dakar, Senegal
2 Cardiology Department of Dalal Djam Hospital, Dakar Senegal
3 Cardiology Department of Aristide Le Dantec Teaching Hospital, Dakar, Senegal
4 Cardiology Department of Fann Hospital, Dakar Senegal
*Corresponding Author: NGAIDE Aliou Alassane, Cardiology Department of Grand Yoff General Hospital, Dakar, Senegal.
Citation: NGAIDE A. Alassane., GAYE N. Diaba., SARR S. Antoine., AW Fatou., Momar D., Maimouna S., et al. (2020) Evaluation of Systolic Function of the Right Ventricle In Patients with Chronic Obstructive Pulmonary Disease: A Cross Sectional Study About 30 Cases. J. Clinical Cardiology and Cardiovascular Interventions, 3(5); Doi:10.31579/2641-0419/052
Copyright: © 2020 NGAIDE Aliou Alassane, This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Received: 24 February 2020 | Accepted: 12 March 2020 | Published: 20 March 2020
Keywords: COPD; systolic function of the right ventricle; senegal
Introduction: Chronic pulmonary heart is the main cardiovascular complication of chronic obstructive pulmonary disease. The aims of our study were to evaluate the right ventricular systolic function in patients with chronic obstructive pulmonary disease and to investigate the relationship between parameters of right ventricular function and pulmonary function testing data.
Methodology: A multicenter cross-sectional study was conducted between January 2013 and July 2013 in cardiology and pulmonology department in Dakar. Was included all in or outpatient diagnosed for chronic obstructive pulmonary disease.
Results: 30 patients were evaluated in this cohort. The mean age was 62.4 years. Male predominance was noted (sex ratio of 9). Right heart failure was found in 7 patients (23.3%) had. Right ventricule enlargement was noted in 12 patients (40%). Mean sPAP was 58.58 ± 23.59 mmHg. Pulmonary arterial hypertension was found in 16 (53.3%) patients. TAPSE was impaired in 7 patients (23.3%). Reduction of right ventricule fractional area change was present in 14 (46.6%) patients. S’ of the tricuspid annulus velocity was reduced in 11 (33%) patients. Parameters correlated with the severity of chronic obstructive pulmonary disease were: TAPSE (p= 0.0099), right ventricule fractional area change (p = 0.0095), S’ of the annular tricuspid (p= 0.0173) TEI index (p= 0.038) and Pulmonary arterial hypertension (p= 0,023).
Conclusion: Evaluation of right ventricular systolic function in chronic obstructive pulmonary disease is fundamental and must use multiple parameters.
The study of the right ventricle has seen a renewed interest in recent years in many pathologies. Unfortunately, even if its prognostic importance is no longer to be proven, the evaluation of the systolic function of the right ventricle is still not systematic. The chronic pulmonary heart (CPC) and right ventricular dysfunction are considered to be the main cardiovascular complications during chronic obstructive pulmonary disease (COPD) [1, 2]. They mark a turning point in the evolution of respiratory disease and conditions the establishment of specific therapies. It is therefore essential to look for a cardiac impact by clinical examination and cardiac Doppler ultrasound [2].
In Senegal, few studies have been devoted to the cardiovascular manifestations of COPD. The objectives of our study were:
- to assess the systolic function of the right ventricle in patients with chronic obstructive pulmonary disease, at different stages of disease severity;
- to analyze the relationship between the different echocardiographic parameters of right ventricular systolic function and the degree of severity of COPD.
This is a cross-sectional, descriptive, multicenter study, conducted from January 2013 to July 2013 carried out in the pulmonology departments of the FANN University Hospital Center and the cardiology departments of the Aristide Le Dantec CHU.
Included was any hospitalized or outpatient patient for COPD with or without evidence of heart dysfunction or exacerbation of COPD. The patients benefited from a complete clinical examination as well as a paraclinical assessment (biological parameters, electrocardiogram, chest chest X-ray, EFR, echocardiography).
Doppler echocardiography made it possible to measure the cavity dimensions, the systolic function of the left ventricle (LV) but especially of the right ventricle (RV). Several parameters of the systolic function of the RV were used: the tricuspid annular plane excursion (TAPSE), the fraction of shortening of the LV (FSLV), the longitudinal speed or peak of the Sa tricuspid wave, the isovolumic acceleration, the TEI index and max dP / dt index. The LV eccentricity index corresponding to the ratio of the anteroposterior and septo-lateral diameter of the left ventricle was measured on a mid-ventricular minor axis section, in telesystole and telediastole.
The diastolic function of the RV was also appreciated. The pulmonary arterial pressure was evaluated by Doppler by the flows of tricuspid insufficiency and / or pulmonary insufficiency. A value below 35 mm Hg was considered normal, however age is taken into account [3]. Pulmonary arterial hypertension (PAH) was severe for a systolic pulmonary arterial pressure (sPAP) value greater than 60 mm Hg. The standards for the various echocardiographic parameters studied were those recommended by the American Society of Echocardiography (ASE) as shown in Table 1 [3].
A systematic respiratory functional exploration (RFE) made it possible to explore the pulmonary ventilatory function in search of an obstructive, restrictive or mixed syndrome and to assess its severity using the GOLD classification [4].
All of the data collected was entered by the Epi data software and analyzed with SPSS 16.0 and Excel software. The description of the qualitative variables was done using percentages and that of the quantitative variables using means and standard deviations. Chi2 and Fisher tests allowed the comparison of proportions. A value of p <0.05 was considered as a threshold of statistical significance.
A total of 30 patients were included over a period of 6 months 15 days. The average age of the patients was 62.4 years [40-83 years]. The age group included [50-64 years] represented 53.3%. The male gender was predominant and represented 90% of the population. The sex ratio (male/female) was 9. A history of pulmonary tuberculosis was found in 5 cases and that of pulmonary embolism in one patient. The average duration of evolution of COPD was 5.08 years.
Signs of right heart failure were found in 23.3% of cases. The average hemoglobin level was 17g/dl. On the electrocardiographic level, a sinus rhythm was found in 27 patients (90%). The electrocardiogram (ECG) was normal in 6 patients (20%). The anomalies were dominated by the right atrial hypertrophy found in 43.3% of the cases (Table 2).
Echocardiographically, the right ventricle was dilated in 12 patients, ie 40% of the cases (Table 4); the same was true for the right atrium (Figure 1).
Nine patients presented with echocardiographic signs of chronic pulmonary heart. There was left atrial and ventricular dilation in 7 cases (23.33%) and 3 cases (10%), respectively. Left ventricular systolic function was impaired in 4 (13.3%) patients. sPAP was measured in 27 patients. Its average was 58.58 mmHg. PAH was noted in 20 patients (74%). It was severe in 13 patients, moderate and mild in 5 and 2 patients, respectively. There was a significant correlation between the presence of PAH and the stage of severity of COPD (p = 0.023).
The average index of eccentricity in telesystole was 1.255; that in telediastole of 1.33. An increase in both indices, witnessing a barometric overload, was noted in 12 (40%) of our patients. Diastolic DV function was abnormal in 12 cases (40%). No cases of relaxation disorder were found. We had 9 cases of pseudo-normal aspect and 3 cases of restrictive disorders. The results of the evaluation of the systolic function parameters were a function of the sPAP and of the existence or not of an exacerbation (Table 5).
The TAPSE was altered in 7 patients and the mean found was 18.20 mm. Its alteration was significantly correlated with the stage of COPD (p = 0.0099). The RV shortening fraction was impaired in 14 patients (46.6%), with an average of 34.95% ± 10.12. The alteration was significantly correlated with the stage of COPD (p-0.0095). The Sa tricuspid index was altered in 11 patients (33%) and was significantly correlated with the stage of COPD (p = 0.0173).
The isovolumic acceleration was abnormal in 6 (20%) of our patients, and not correlated at the stage of COPD (p = 0.09). The TEI index could be calculated in 23 patients and was abnormal in 17 (73.9%) patients. Its mean value was 0.60 and it was significantly correlated with the severity of COPD (p = 0.038). The dP/dt index could be assessed in 16 patients. It was less than 400 mmHg/s in 5 of them (26%) and not correlated at the stage of COPD (p = 0.3296), with an average of 539.5 mmHg/s. Thirteen patients, or 43% of the study population, had an impairment of at least three of the systolic function indices.
The data collected from the RFE made it possible to classify the patients according to the progressive stage of COPD (Table 6). Two patients had an improvement in their sub-bronchodilator numbers, no total reversibility was noted.
The prevalence of right heart failure in our study was 23.3%. Gūder G [5] found a prevalence of 17%. Right atrial hypertrophy and RV hypertrophy were present in 43.3 and 36.6% of the cases, respectively. These two electrocardiographic signs were mainly found when the stage of COPD was advanced; a finding found in the study of Sharma et al [6] and in that of Warnier et al [67], more, Holtzman et al [8] demonstrated that the sensitivity, specificity, positive and negative predictive value of the ECG relating to RVH in COPD were 50%, 100%, 100%, and 75%, respectively. The chest chest X-ray showed cardiomegaly and signs of PAH in 40% and 20% of the cases, respectively. Himelman et al [9] found cardiomegaly and signs of PAH in 18% and 21% of their patients, respectively. Gupta S et al [10] found 20% cardiomegaly and 36.6% signs of PAH. We found left ventricular dysfunction in Simpson biplane in 4 (13.3%) patients and longitudinal systolic dysfunction in 5 patients (16.6%). The mean EFLV value for the Simpson biplane was 63%; and the results obtained in other studies seem, on the whole, similar to those described in the literature [11, 12, 13].
Left ventricular dysfunction during COPD is due to many factors, such as hypoxemia and acidosis, involvement of the coronary arteries, or ventricular interdependence. In addition, some studies claim that if LV systolic dysfunction is possible during COPD without PAH, it worsens with the value of PAPS [10, 14]. Nine patients (30%) had echocardiographic signs of chronic pulmonary heart. Gupta [10] and Maula [15] found 17.5% and 32.7% respectively during their studies. The alteration of the diastolic function of the RV, found in 40% of the cases, would be related to the hypertrophy / dilation of the latter. The study by Tei et al [16] effectively shows that PAH leads to an impairment of the systolic and diastolic function of RV; this was confirmed by Vizza et al [17] who highlighted the diastolic dysfunction of RV during COPD. We found PAH in 72.7% of cases as well as a positive correlation between the stage of COPD and PAH. Gupta [10] and Maula [15] found 42.5% and 65.4% respectively of patients who had PAH, and also found a significant correlation between the stage of COPD and the severity of PAH. This correlation can be explained by that which exists between variations in PaO2 and pulmonary arterial pressure [18]. There is a monumental worsening of PAH during episodes of exacerbation of COPD which is explained by the worsening of hypoxemia and hypercapnia [2, 19]. The right ventricular function ultrasound assessment is complex due to the anatomy and position of the LV, thus requiring the combination of several parameters.
During our study, we were able to highlight a relation between the deterioration of the indices of systolic function of the RV and the stage of the COPD and the presence or not of signs of clinical exacerbation on the one hand, and the presence and the severity of PAH on the other hand. In fact, if we compare a group of patients with mild to moderate COPD to that of severe to very severe COPD, the impairment of SFRV is significantly more marked in the moderate to severe COPD group (p = 0.0095). This correlation is significant for TAPSE (p = 0.0099), Sa tricuspid (p = 0.0173) and the Tei index (p = 0.038), but not significant for isovolumic acceleration (p = 0.09). Concerning the Tei index, if its alteration seems more marked in patients with PAH (0.71 + 0.42), it seems less sensitive to the presence or not of an exacerbation, with an average of 0, respectively. 61 ± 0.40 and 0.59 ± 0.37.
Botelho [19] as well as Ozben [20] also found, by comparing the results before and after the treatment of the COPD exacerbation, a relatively stable Tei index, but there was a significant difference notably for the isovolumic acceleration [20] (p = 0.013). The alteration of at least 3 indices of the systolic function of RV in the same subject was present in 62.5% of patients with severe or very severe COPD against 21.4% of cases of mild to moderate COPD (p = 0.0235 ).
Right ventricular systolic dysfunction is commonly associated with PAH. Moreover, the recommendations issued by the European Cardiology Society [21] on the diagnosis of PAH in ultrasound, confirm the need to assess the right ventricular function in PAH. Concerning the disparity of the results obtained between the indices used during our study, it would be linked to the fact that all the parameters of evaluation of the right ventricular function, starting with the EFRV which is however considered as the "gold standard", are very sensitive to load conditions. Indeed, there is no real parameter of contractility of the RV which is independent of it, apart from perhaps the pulmonary elastance measured from the pressure/volume loops in hemodynamics [22]. In addition, if the TAPSE has already shown its interest in the evaluation of the EFRV with an excellent correlation coefficient between the TAPSE and the EFRV, it has however limits linked to the fact that the evaluation relates only to the longitudinal function of the free wall of the RV, without taking into account the contribution of the interventricular septum, the radial function, or the circumferential function, whereas these could have an important role in maintaining the right ventricular function when the contraction longitudinal decreases [23]. Finally, if the SFRV is well correlated with the EFRV evaluated by myocardial MRI and is superior to other two-dimensional evaluation methods [24], it also has the main advantage of taking into account the participation of the interventricular septum. However, the numerous RV trabeculations make it difficult to define the endocardium and are therefore a source of bias [25].
For the past few years, we have known the prognostic importance of RV dysfunction, especially in COPD. The estimation of the right cardiac repercussion is essential because it marks an evolutionary turning point in the evolution of respiratory disease.
None
Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. Auctoresonline publishing platform can be used to facilitate of optimal client-based services and should be added to health care professionals' repertoire of evidence-based health care resources.
Journal of Clinical Cardiology and Cardiovascular Intervention The submission and review process was adequate. However I think that the publication total value should have been enlightened in early fases. Thank you for all.
Journal of Women Health Care and Issues By the present mail, I want to say thank to you and tour colleagues for facilitating my published article. Specially thank you for the peer review process, support from the editorial office. I appreciate positively the quality of your journal.
Journal of Clinical Research and Reports I would be very delighted to submit my testimonial regarding the reviewer board and the editorial office. The reviewer board were accurate and helpful regarding any modifications for my manuscript. And the editorial office were very helpful and supportive in contacting and monitoring with any update and offering help. It was my pleasure to contribute with your promising Journal and I am looking forward for more collaboration.
We would like to thank the Journal of Thoracic Disease and Cardiothoracic Surgery because of the services they provided us for our articles. The peer-review process was done in a very excellent time manner, and the opinions of the reviewers helped us to improve our manuscript further. The editorial office had an outstanding correspondence with us and guided us in many ways. During a hard time of the pandemic that is affecting every one of us tremendously, the editorial office helped us make everything easier for publishing scientific work. Hope for a more scientific relationship with your Journal.
The peer-review process which consisted high quality queries on the paper. I did answer six reviewers’ questions and comments before the paper was accepted. The support from the editorial office is excellent.
Journal of Neuroscience and Neurological Surgery. I had the experience of publishing a research article recently. The whole process was simple from submission to publication. The reviewers made specific and valuable recommendations and corrections that improved the quality of my publication. I strongly recommend this Journal.
Dr. Katarzyna Byczkowska My testimonial covering: "The peer review process is quick and effective. The support from the editorial office is very professional and friendly. Quality of the Clinical Cardiology and Cardiovascular Interventions is scientific and publishes ground-breaking research on cardiology that is useful for other professionals in the field.
Thank you most sincerely, with regard to the support you have given in relation to the reviewing process and the processing of my article entitled "Large Cell Neuroendocrine Carcinoma of The Prostate Gland: A Review and Update" for publication in your esteemed Journal, Journal of Cancer Research and Cellular Therapeutics". The editorial team has been very supportive.
Testimony of Journal of Clinical Otorhinolaryngology: work with your Reviews has been a educational and constructive experience. The editorial office were very helpful and supportive. It was a pleasure to contribute to your Journal.
Dr. Bernard Terkimbi Utoo, I am happy to publish my scientific work in Journal of Women Health Care and Issues (JWHCI). The manuscript submission was seamless and peer review process was top notch. I was amazed that 4 reviewers worked on the manuscript which made it a highly technical, standard and excellent quality paper. I appreciate the format and consideration for the APC as well as the speed of publication. It is my pleasure to continue with this scientific relationship with the esteem JWHCI.
This is an acknowledgment for peer reviewers, editorial board of Journal of Clinical Research and Reports. They show a lot of consideration for us as publishers for our research article “Evaluation of the different factors associated with side effects of COVID-19 vaccination on medical students, Mutah university, Al-Karak, Jordan”, in a very professional and easy way. This journal is one of outstanding medical journal.
Dear Hao Jiang, to Journal of Nutrition and Food Processing We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.
As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.
Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.
International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.
Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.
Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.
I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!
"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".
I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.
We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.
I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.
I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.
I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.
Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.
“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.
Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.
The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.
Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.
My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.
My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.
