Employment of Resonators for Resolution Enhancement in Plasmonic Refractive Index Sensors

Review Article | DOI: https://doi.org/10.31579/2639-4162/115

Employment of Resonators for Resolution Enhancement in Plasmonic Refractive Index Sensors

  • Hamid Abbasi *

Atomoc and molecular of Physics group, faculty of basic science, University of Mazandaran, Babolsar

*Corresponding Author: Hamid Abbasi, Atomoc and molecular of Physics group, faculty of basic science, University of Mazandaran, Babolsar.

Citation: Hamid Abbasi, (2023), Employment of Resonators for Resolution Enhancement in Plasmonic Refractive Index Sensors, J. General Medicine and Clinical Practice. 6(7); DOI:10.31579/2639-4162/115

Copyright: © 2023, Hamid Abbasi. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

Received: 09 November 2023 | Accepted: 28 November 2023 | Published: 06 December 2023

Keywords: plasmonics; Surface plasmon polaritons; Metal-Insulator-Metal; refractive index sensor

Abstract

In this paper, a plasmonic refractive index sensor based on metal insulated metal waveguide (MIM) with three rings and a resonant cavity is first proposed and numerically evaluated. Next, we add four teeth to the sensor structure. We study and simulate the resonant wavelengths and refractive index of resonators using the time difference finite difference method. Given that the sensor and the conduction characteristics of plasmonic waves are influenced by the structure parameters, Therefore, by changing the refractive index and changing the dimensions and coordinates of the cavity and rims, we can change the passage coefficient in the resonant modes and measure the sensor performance. As a result, we obtain the sensitivity coefficient, the figure of merit (FOM) and the quality factor Q of the sensor. We modulate the resonance wavelength FWHM using the generated modes and reach a sensitivity of 2166 nm / RIU. These plasmonic sensors with a simple framework and balanced performance and high optical resolution can be used to measure the refractive index in the medical, chemical and food industries.

Introduction

The attractive feature of surface plasmon polarities (SPP), ie the restriction of light in nano-dimensions, has caused this phenomenon to be widely studied and this feature can be used to build many plasmonic structures such as filters [1], multiple optical instruments [2], absorbers [3], splitters [4] and sensors [5- 13]. Also, metal-insulated-metal plasmonic waveguide (MIM) due to its ability to limit light in a small area and its compatibility with electronic operating systems is widely used in the design of many plasmonic devices. In addition, having a simple design method of these structures has made them one of the most desirable and popular structures. As a result, a variety of MIM plasmonic devices have been designed and implemented [14,15]. Many criteria can be used to design and implement refractive index sensors, one of which is the calculation of good sensitivity (S) and figure of merit (FOM) [16- 24]. For this reason, researchers have made great efforts to improve the sensitivity of MIM plasmonic sensors, but longer wavelengths always suffer from wider FWHM, which reduces the figure of merit (FOM) and sensitivity coefficient. Recently, to enhance the performance of plasmonic sensors, various approaches have been used, such as Fano resonance with dark and light resonance interference, which results from structural symmetry failure or resonance interference, but such resonance is unstable and can be easily broken due to phase or mode mismatch. In this study, arrays of metal-dielectric-metal (MIM) plasmonic waveguides and resonators are designed, simulated and analyzed to design and fabricate plasmonic sensors. The two-dimensional finite difference time domain (FDTD) method is used to simulate the sensor. Boundary conditions for all directions are selected as the perfectly matched layer (PML). To simulate FDTD, a uniform mesh size of 8 nm was used.

Structural model and theory analysis

As shown in Fig.1, two MIM waveguides coupled with three rings and a cavity are proposed. The waveguides are etched on the silver surface. As shown in 2D picture, the grey and white areas represent silver and air, respectively. The permittivity of air is set as εi = 1, as for silver (Ag) the Drude model is utilized as follows [1]:

                                                                                                       ε )ω(= ε∞ - ωp2 / ω2+ iϒω            (1)

                                                                                            Figure 1: Two-dimensional image of a plasmonic sensor

The height of the two waveguides is w1 = 50 nm. The cavity has a height of w2 = 130 nm and a length of L1 = 92 nm. The middle ring has an inner radius of r1 = 90 nm and an outer radius of R1 = 133 nm and the two side rims have an inner radius of r3 = r2 = 91 nm and an outer radius of R3 = R2 = = 126 nm, respectively.Pin and Pout are the monitors for measuring the input wave and the output wave, respectively. These two monitors are computed by merging the natural component of the Poin Ting vector along the blurred lines. As a result, the wave transmission is calculated by the relation

                                                                                                                       T = Pout / Pin                        (2)

Surface plasmon polarites (SPP) TM mode, when attached to the MIM structure, can propagate at the interface level in the waveguide. Compared to the excited wavelength, the width of the bass waveguide is much smaller, so only the TM base mode can only participate in the sensor simulation. The input wave starts moving from the left and after passing through the rings and cavities, it goes to the output waveguide. The silicon substrate is made of silver and the reason for this is to strengthen the performance of the refractive index [25]. We also use the following equations to calculate the TM wave scattering relationship [15]:

                                                                             

 Here ω refer to the width of bus waveguide, λ shows incident light wavelength in vacuum, εi and εm give the relative dielectric and metal permittivity, βspp and neff are propagation constant and effective refractive index of SPPs, and =2π⁄λ k0 means wave number. Two-dimensional simulation is used to enhance sensor performance and achieve more accurate results and reduce simulation time. We must also choose the right height for the input wave, because too much wave height will reduce the wave penetration into the sensor structure and reduce the refractive index (can lead to longer propagation length) [26]. To describe the wave behavior, we draw a field distribution diagram (Fig.2(. According to the figure, the wave goes to the resonators after starting to move. The resonant system is now considered as a single loop resonator whose effective radius is determined by the energy distribution. The middle cavity gets the largest share of the field distribution and creates a uniform state with the internal phase

                                                                                          Figure 2: Electric field distribution at resonant frequency

MIM waveguide transmission spectra for different modes are plotted in Fig.3. When the middle ring is present in the sensor structure with one of the other three resonator (R2 ring or R3 ring or cavity), the transmission spectrum has three peaks But when all four resonator (R1 ring, R2 ring, R3 ring and cavity) are present in the sensor structure, the transmission spectrum has two peaks. Also, the wavelength change in this diagram (R1 ring, R2 ring, R3 ring and cavity) is more and will reach a higher sensitivity factor. Therefore, we use the following equation to calculate the resonance conditions:

                                                                                                           Nλ = Re (neff) Leff, N = 1, 2, 3….      (7)

Where N refers to mode number which is an integer. neff refers to the effective refractive index of the ring resonator which can be solved by Eq (6), Leff means effective perimeter, generally refers to the average of the inner 

                                                                                 Figure 3: MIM waveguide transmission spectrum with resonators

Fracture coefficient simulation and measurement methods

The proposed plasmonic resonance behavior is investigated numerically and theoretically. For the numerical approach, we use the finite difference method of time domain with perfectly matched layer boundary conditions (PML) because this method effectively reduces numerical reflection. The uniform mesh sizes for the x and y directions are 8 and 8 nm, respectively. The transmission line model is used to analyze the structure theory and the simulation is done in two dimensions, which is infinite in one dimension. We change the effective refractive index of the middle ring to evaluate the performance of the sensor. This change in refractive index is calculated in the wavelength range of 400 to 1500 nm and the transmission spectrum from the sensor device is shown in Figure.4. We increased the dielectric refractive index by a step of 0.01 from 1.15 to 1.2, which resulted in a change in the resonance spectra and wavelengths.

Figure 4: Transmission spectra of a plasmonic refractive index sensor

We increased the dielectric refractive index by a step of 0.01 from 1.15 to 1.2 nm, which resulted in a change in the resonance spectra and wavelength. The first characteristic to be measured for a sensor is the S sensitivity, which is used to quantify the sensitivity of refractive index sensors:

                                                                                                                   S = Δ λ/ Δn (nm/RIU)             (8)

In this equation, Δλ is the change in resonance wavelength and Δn is the change in refractive index. According to Fig.5, the sensor transmission spectra have two peaks, which according to Figure 4, have the highest sensitivity for the refractive index n = 1.2, which is equal to 1938 nm / RIU. According to this diagram, there is a relatively linear relationship between the two parameters of resonance wavelength and refractive index.

                                                                                             Figure 5: Plasmonic sensor sensitivity coefficient diagram

Because sensitivity alone is not a measure of good performance for comparing different types of sensors, and light resolution is also very important for sensors, figure of merit (FOM) is required to compare sensors:

                                                                                                                            FOM = S / FWHM  (9)

                                                                                                           Figure 6. Plasmonic sensor FOM diagram

We also need the quality factor of the sensors:

                                                                                             Figure 7: Plasmonic sensor quality coefficient diagram

According to Figure7, the quality coefficient is obtained by using Equation 10 by dividing the wavelength by FWHM, whose value in the refractive index n = 1.2, which has the highest sensitivity coefficient, reaches 8.934. Equations 8, 9 and 10 are the Measurement capabilities of plasmonic sensors obtained by changing the refractive index of the structure. Using these three equations, we plot the coefficients of sensitivity, quality, and figure of merit.

Sensitivity analysis of the sensor by adding four teeth

Now for better evaluation and to achieve a better quality sensor, we add four teeth with length x1 = x3

= 20, x2 = x4 = 40, height y1 = y3 = 40 and y2 = y4 = 20, to the middle ring. The added teeth have an effect on the intensification of the middle ring, which changes the intensification wavelength or creates a new state. We change the refractive index of the middle ring and the refractive index of the other two rings and the teeth and the cavity and the two waveguides remain constant.

                                                                 Figure 8: Sensitivity diagram of a plasmonic sensor with four teeth added

The transmission spectrum of the sensor device is shown in Figure.9. According to this diagram, there is a relatively linear relationship between the two parameters of resonant wavelength and refractive index, and the TM resonance in the range of 400 to 1500 nm, gradually shifting Gives.

                                                                                  Figure 9: Transmission spectra of a plasmonic refractive index sensor

By changing the refractive index by step 0.01 in the range 1.15 to 1.2, we obtain the sensitivity coefficient of the new structure using Equation 8 and plot it (Figure.10).

                                                                                            Figure 10: Plasmonic sensor sensitivity coefficient diagram

The refractive index diagram in Fig.10 examines the peaks in Fig.9. In the left peak, all sensitivity coefficients are equal to zero, but the right peak has good results and the highest sensitivity coefficient is equal to 2166 nm / RIU. The result is better than many similar articles. We now examine the figure of merit (FOM) of the designed sensor. Using Equation 9, we obtain its diagram and draw it.

                                                                                                    Figure 11. Plasmonic sensor FOM diagram

Like the sensitivity coefficient, all mode 1 numbers of the figure of merit (FOM) are zero, but mod 2 has better quality and the highest FOM value is 18.447. The next criterion for measuring the performance of this sensor is the quality factor Q.

                                                                                              Figure 12:  Plasmonic sensor quality coefficient diagram

The quality coefficient Q at n = 1.16 (which has the highest sensitivity coefficient) reaches 8.164 nm.

Bio-sensing

Finally, we review an application for bioassay. The structure parameters remain constant. Since water is one of the most common solvents used in chemical and biological applications, it is necessary to test the performance of the sensor in water (n=1.33) as presented in Fig.13. Since the concentration of the solution can be reflected by the refractive index, a set of different refractive index values around the water is used to measure the sensitivity and the figure of merit (FOM).

                                                                              Figure 13: Two-dimensional image of a plasmonic sensor in water.

The transmission spectrum from the sensor device is shown in Figure.14. We have increased the refractive index of the middle cavity by a step of 0.0 nm from 1.34 to 1.38.

                                                                            Figure.14. Transmission spectrum of a plasmonic sensor in water.

Using the transfer spectrum and using Equation 8, we calculate the sensitivity coefficient of the plasmonic sensor in water, which reaches the sensitivity coefficient of 2604 nm / RIU. This sensitivity coefficient is higher than similar tasks and proves that this designed sensor has high quality and good performance and also has a very good performance in water (Figure.15). Therefore, such structure can be a sensitive label-free and compact biosensor

                                                                             Figure 15: Plasmonic sensor sensitivity coefficient diagram in water

Conclusion

A new topology was proposed and analyzed to measure the refractive index. The proposed configuration has a high sensitivity of 2166 nm / RIU. This sensor is considered because a small change in the refractive index of the middle ring causes a significant change in the propagation characteristics of the wave. It also has a high sensitivity as a sensor in bioassay and has excellent performance with high optical resolution. The plasmonic sensor in water reaches a sensitivity factor of 2604 nm / RIU. Our results and physical analysis due to the small size of the structure and high sensitivity coefficient can cause excellent light control in plasmonic structures and also reduce losses.

Funding: This research received no external funding.

Disclosures. The author declares no conflicts of interest.

Data Availability. No data were generated or analyzed in the presented research.

References

Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. Auctoresonline publishing platform can be used to facilitate of optimal client-based services and should be added to health care professionals' repertoire of evidence-based health care resources.

img

Virginia E. Koenig

Journal of Clinical Cardiology and Cardiovascular Intervention The submission and review process was adequate. However I think that the publication total value should have been enlightened in early fases. Thank you for all.

img

Delcio G Silva Junior

Journal of Women Health Care and Issues By the present mail, I want to say thank to you and tour colleagues for facilitating my published article. Specially thank you for the peer review process, support from the editorial office. I appreciate positively the quality of your journal.

img

Ziemlé Clément Méda

Journal of Clinical Research and Reports I would be very delighted to submit my testimonial regarding the reviewer board and the editorial office. The reviewer board were accurate and helpful regarding any modifications for my manuscript. And the editorial office were very helpful and supportive in contacting and monitoring with any update and offering help. It was my pleasure to contribute with your promising Journal and I am looking forward for more collaboration.

img

Mina Sherif Soliman Georgy

We would like to thank the Journal of Thoracic Disease and Cardiothoracic Surgery because of the services they provided us for our articles. The peer-review process was done in a very excellent time manner, and the opinions of the reviewers helped us to improve our manuscript further. The editorial office had an outstanding correspondence with us and guided us in many ways. During a hard time of the pandemic that is affecting every one of us tremendously, the editorial office helped us make everything easier for publishing scientific work. Hope for a more scientific relationship with your Journal.

img

Layla Shojaie

The peer-review process which consisted high quality queries on the paper. I did answer six reviewers’ questions and comments before the paper was accepted. The support from the editorial office is excellent.

img

Sing-yung Wu

Journal of Neuroscience and Neurological Surgery. I had the experience of publishing a research article recently. The whole process was simple from submission to publication. The reviewers made specific and valuable recommendations and corrections that improved the quality of my publication. I strongly recommend this Journal.

img

Orlando Villarreal

Dr. Katarzyna Byczkowska My testimonial covering: "The peer review process is quick and effective. The support from the editorial office is very professional and friendly. Quality of the Clinical Cardiology and Cardiovascular Interventions is scientific and publishes ground-breaking research on cardiology that is useful for other professionals in the field.

img

Katarzyna Byczkowska

Thank you most sincerely, with regard to the support you have given in relation to the reviewing process and the processing of my article entitled "Large Cell Neuroendocrine Carcinoma of The Prostate Gland: A Review and Update" for publication in your esteemed Journal, Journal of Cancer Research and Cellular Therapeutics". The editorial team has been very supportive.

img

Anthony Kodzo-Grey Venyo

Testimony of Journal of Clinical Otorhinolaryngology: work with your Reviews has been a educational and constructive experience. The editorial office were very helpful and supportive. It was a pleasure to contribute to your Journal.

img

Pedro Marques Gomes

Dr. Bernard Terkimbi Utoo, I am happy to publish my scientific work in Journal of Women Health Care and Issues (JWHCI). The manuscript submission was seamless and peer review process was top notch. I was amazed that 4 reviewers worked on the manuscript which made it a highly technical, standard and excellent quality paper. I appreciate the format and consideration for the APC as well as the speed of publication. It is my pleasure to continue with this scientific relationship with the esteem JWHCI.

img

Bernard Terkimbi Utoo

This is an acknowledgment for peer reviewers, editorial board of Journal of Clinical Research and Reports. They show a lot of consideration for us as publishers for our research article “Evaluation of the different factors associated with side effects of COVID-19 vaccination on medical students, Mutah university, Al-Karak, Jordan”, in a very professional and easy way. This journal is one of outstanding medical journal.

img

Prof Sherif W Mansour

Dear Hao Jiang, to Journal of Nutrition and Food Processing We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.

img

Hao Jiang

As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.

img

Dr Shiming Tang

Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.

img

Raed Mualem

International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.

img

Andreas Filippaios

Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.

img

Dr Suramya Dhamija

Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.

img

Bruno Chauffert

I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!

img

Baheci Selen

"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".

img

Jesus Simal-Gandara

I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.

img

Douglas Miyazaki

We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.

img

Dr Griffith

I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.

img

Dr Tong Ming Liu

I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.

img

Husain Taha Radhi

I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.

img

S Munshi

Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.

img

Tania Munoz

“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.

img

George Varvatsoulias

Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.

img

Rui Tao

Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.

img

Khurram Arshad