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Research Article | DOI: https://doi.org/10.31579/2692-9392/227
Daswani Dental College Affliated to Rajasthan University of Health Sciences, India.
*Corresponding Author: Ashish Pandey, Daswani Dental College Affliated to Rajasthan University of Health Sciences, India.
Citation: Ashish Pandey, Gunjan Tomar, Haripriya Katira, Aanchal Singh, Komal Mittal, (2025), Custom-Made Titanium Implants for Mandibular Reconstruction, Archives of Medical Case Reports and Case Study, 10(1); DOI:10.31579/2692-9392/227
Copyright: © 2025, Ashish Pandey. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 29 January 2025 | Accepted: 06 February 2025 | Published: 12 February 2025
Keywords: mandibular reconstruction; custom-made implants; titanium; 3d printing; patient-specific implants; additive manufacturing
Mandibular defects caused by trauma, tumor resection, or congenital anomalies present significant challenges in oral and maxillofacial surgery. Conventional methods such as autogenous bone grafts and standard titanium plates have limitations, including donor site morbidity and suboptimal functional outcomes. Advances in additive manufacturing, particularly 3D printing technologies like Selective Laser Melting (SLM) and Electron Beam Melting (EBM), have enabled the fabrication of patient-specific titanium implants. These implants offer precise anatomical fit, improved aesthetic and functional outcomes, and reduced surgical time. Despite their advantages, challenges such as cost, long-term durability, and regulatory compliance persist. This review discusses the advancements, fabrication processes, clinical applications, and future perspectives of custom-made titanium implants in mandibular reconstruction.
Mandibular reconstruction is essential in restoring function and aesthetics in patients with mandibular defects caused by trauma, tumor resection, or congenital anomalies. Traditional methods, including autogenous bone grafts and standard titanium plates, have inherent limitations such as donor site morbidity, increased surgical time, and suboptimal restoration of mandibular form and function [1]. The emergence of additive manufacturing (AM) and advanced imaging techniques has led to the development of custom-made titanium implants, which are designed to match individual patient anatomy, offering superior clinical outcomes [2].
Advancements in Additive Manufacturing
Additive manufacturing (AM), commonly referred to as 3D printing, has revolutionized implant fabrication by enabling the production of complex geometries with high precision. The primary AM techniques used for custom-made titanium implants are Selective Laser Melting (SLM) and Electron Beam Melting (EBM).
SLM employs a high-powered laser to selectively fuse metallic powders layer by layer, allowing for intricate structures with controlled porosity and surface roughness [3]. EBM, in contrast, utilizes an electron beam for metal fusion, providing advantages in build speed and mechanical properties [4]. These techniques facilitate the fabrication of highly customized implants with optimized biomechanical properties, enhancing osseointegration and reducing stress shielding effects.
Design and Fabrication Process
The development of patient-specific titanium implants begins with high-resolution imaging, typically obtained through computed tomography (CT) or cone beam computed tomography (CBCT) scans. These scans generate a 3D digital model of the patient’s mandible, which serves as a blueprint for implant design using computer-aided design (CAD) software [5].
The finalized design is then fabricated using SLM or EBM technology, ensuring high structural integrity and biocompatibility. Surface modifications, such as porous structures, are incorporated to enhance osseointegration and promote soft tissue integration [6].
Clinical Applications and Outcomes
Several clinical studies have demonstrated the efficacy of custom-made titanium implants in mandibular reconstruction. A study by Ciocca et al. [7] reported the use of 3D-printed subperiosteal titanium implants for the prosthetic restoration of the atrophic posterior mandible. These implants, designed based on CBCT data and fabricated using Direct Metal Laser Sintering (DMLS), demonstrated excellent fit, stability, and successful functional restoration.
Li et al. [8] described the reconstruction of maxillofacial bone defects using patient-specific titanium implants produced via SLM and EBM. The results showed successful mandibular continuity restoration, improved aesthetics, and no significant complications. These findings highlight the potential of custom-made implants in complex maxillofacial reconstructions.
Custom-made titanium implants offer several advantages over conventional mandibular reconstruction techniques:
Despite their numerous advantages, custom-made titanium implants present certain challenges:
The integration of additive manufacturing and advanced imaging technologies has significantly improved mandibular reconstruction outcomes through the development of custom-made titanium implants. These implants provide superior fit, functionality, and aesthetic outcomes compared to traditional methods. However, further research is needed to assess their long-term durability, cost-effectiveness, and wider clinical applicability. As technological advancements continue, custom-made titanium implants will likely become a standard in mandibular reconstruction.
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