Curbing Diarrhea in Children below five years old: The sub-Saharan African Standpoint

Review Article | DOI: https://doi.org/10.31579/2767-7370/083

Curbing Diarrhea in Children below five years old: The sub-Saharan African Standpoint

  • Esther Ugo Alum 1,2
  • Emmanuel Ifeanyi Obeagu 3*
  • Okechukwu P. C. Ugwu 1

1 Department of Research Publications and Extension, Kampala International University, P. O. Box 20000, Uganda.

2 Department of Biochemistry, Faculty of Science, Ebonyi State University, P.M.B. 053 Abakaliki, Ebonyi State, Nigeria.

3 Department of Medical Laboratory Science, Kampala International University, Uganda

*Corresponding Author: Emmanuel Ifeanyi Obeagu, Department of Medical Laboratory Science, Kampala International University, Uganda.

Citation: Esther Ugo Alum, Emmanuel Ifeanyi Obeagu, Emmanuel Ifeanyi Obeagu, (2024), Curbing Diarrhea in Children below five years old: The sub-Saharan African Standpoint, J. New Medical Innovations and Research, 5(1); DOI:10.31579/2767-7370/083

Copyright: © 2024, Emmanuel Ifeanyi Obeagu.This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: 14 January 2024 | Accepted: 22 January 2024 | Published: 30 January 2024

Keywords: curbing; diarrhea; Sub-Saharan Africa; standpoint; children below 5 years of age; gastrointestinal infection; WHO; child health

Abstract

Diarrhea is the second foremost reason for death in children below 5 years old in the sub-Saharan African region. Insufficient cleanliness, food insecurity, and inadequate health facilities are markers of SSA and thus contribute to high rates of diarrhea in this area. Diarrhea can trigger worry in the family due to the increased financial costs of fighting the illness. Frequent episodes of diarrhea can put physical and mental stress on mothers and caregivers, not to mention the cost of treating diarrhea, placing an additional burden on an already declining health sector. Several factors influence the occurrence of diarrhea in kids: socioeconomic, environmental, and behavioral factors. Measures to prevent diarrhea include using clean water, practicing better hygiene, washing hands with soap, and providing adequate and complete vaccination. A blend of clean water, sugar, and salt, commonly termed oral rehydration solution (ORS), is used to treat diarrhea. Zinc supplements may improve recovery from diarrhea. Despite the preventable and treatable nature of diarrhea, the rate of deaths among children in the sub-Saharan African region due to diarrhea is unfathomable. Therefore, it is necessary to quickly re-establish mechanisms to combat this threat. In this article, we reviewed the frequency of diarrhea in children living in sub-Saharan African regions, its impact, and the factors that promote its persistence. We also suggested measures that can be taken to combat this childhood monster while enhancing existing control and treatment measures. We used data from articles published in various reputable databases.

Introduction

The World Health Organization (also known as WHO) describes diarrhea as " a total of three or more watery or free stools within a day or a greater frequency of feces than customary episodes for an individual” [1]. Globally, one out of nine child mortalities is caused by diarrhea, despite the fact that the majority of these deaths can be avoided with basic, affordable remedies. This translates to 801,000 children globally dying from diarrhea per year or 2,195 children dying from it every day, or the loss of 32 school buses occupied with kids each day [2]. Diarrhea kills 0.53 million children beyond age 5 per year globally, accounting for 4 out of every 1,000 live births, according to 2015 WHO data [3].  Diarrhea is specifically the second foremost reason for death of children below five years old, and the main cause of malnutrition. The group most at risk of fatal diarrhea in children, especially those who are malnourished or have a compromised immune system [1]. Sub-Saharan Africa has an infant mortality rate orchestrated by diarrhea 15 times greater than developed nations [4]. Diarrhea is typically a sign of a gastrointestinal infection triggered by some bacteria, viruses, and protozoa. Insufficient cleanliness may trigger an infection to spread from person to person or via polluted food and water [5, 6]. Measures to avoid diarrhea include consuming safe drinking water, and proper cleanliness practices, including washing hands with soap [1]. Diarrhea comes in three diverse forms: acute watery diarrhea, which may comprise cholera and lingers for several hours or days; acute bloody diarrhea, also called dysentery; and persevering diarrhea, which may endure for two weeks.

A blend of unpolluted water, sugar, and salt, commonly termed Oral rehydration solution (ORS) is used to manage diarrhea. Additionally, a 10–14-day intake of zinc tablets (20 mg) in combination with other approved care reduces diarrhea span and also enhances treatment results [1].

Rotavirus, Cryptosporidium, Shigella, and Escherichia coli are the main pathogens causing diarrhea in children under five years of age [7]. During the first two years of life, the commonest organisms causing diarrhea are norovirus, rotavirus, Campylobacter, astrovirus, Cryptosporidium, and Shigella, according to Platts-Mills et al. [8].

In this paper, we illuminated diarrhea prevalence in children resident in the Sub-Saharan African region, the impact of diarrhea, and the factors influencing its existence. We also suggested measures that could be employed in the fight against this pediatric monster while strengthening the prehistoric measures. Data from published articles in various were utilized. Search key terms used were diarrhea, diarrhea prevalence in the Sub-Saharan African region, diarrhea in children below five years, its impact, factors influencing diarrhea prevalence, and diarrhea intervention strategies. Journal articles and related papers from 2010-2023 were utilized.

Diarrhea In Children Below Five Years Old in Sub-Saharan Africa: Prevalence

Globally, there are an estimated 1.7 billion cases of pediatric diarrhea annually [1]. It is projected that over 80% of the 1.8 million individuals who pass away each year in developing nations from diarrheal diseases are children below five years old [11]. In developing countries, over 90% of pediatric deaths in infants below the age of five are due to diarrhea. Particularly, 88% of deaths in this age bracket occurred in Southern Asia and sub-Saharan Africa (SSA) [12]. The projected total number of Disability-adjusted life years (DALYs) as a result of diarrhea in SSA was 13% in 2019, in line with the Global Burden of Diseases (GBD) report [9, 10]. Lack of sanitation facilities is the key source of diarrhea [13]. In SSA, access to good water, improved sanitation, and hygiene (WASH) is very limited [13] and the prevalence of diarrhea is unfathomable compared to the rest of the world. According to the Global Burden of Disease Vision Center statement, the total number of DALYs in children under 5 years old in East Africa due to diarrhea is 10.21% [10]. Various research studies have reported that the prevalence of diarrhea in children especially those below 5 years old is very high in East Africa. According to a meta-analysis piloted in Ethiopia, the prevalence of diarrhea ranged from 19-25% [14]. Related research carried out in Uganda, Rwanda, and Malawi showed a prevalence of diarrhea of 32% [15], 26.7% [16] and 20% [17], respectively. In addition, open defecation culture is common in East Africa. A systematic review conducted in Ethiopia found a small proportion of areas devoid of open defecation (exactly 16%) [18]. Similar investigations show that the proportion of communities not open defecating in Kenya (14%) [19], and Uganda (22.9%) [20] is low. In general, access to basic sanitation and hygiene facilities is very low in East African countries [21]. The total prevalence of diarrhea is 15.3%, according to Demissie et al. [22] in their investigation to ascertain the prevalence of diarrhea and their connected variables in infants below 5 years old in 34 countries in sub-Saharan Africa. This figure exceeds that of comparable studies done in other areas, such as Central America, where it is 13.0% [23], Vietnam, where it is 11% [24], and India, where it is 5% [25]. These discrepancies could be the result of various environmental and infrastructure conditions in these areas [14]. 

Impact of Diarrhea

Emotional Impact

As the primary mothers or caregivers are in charge of all home duties, including caring for their children, having frequent episodes of diarrhea can be physically and emotionally taxing on them. Intensive care unit caregivers spend almost 30% of their work period at home washing up diarrhea, according to a study [26]. Over two caregivers were required to treat diarrhea 70% of the time, according to survey participants, and 69% said that this assistance was readily available. Sadly, the staff who were put to the test stated that they were frustrated with cleaning up diarrhea roughly 50% of the time [26].

Economic Impact

In addition, diarrhea can trigger worries in the family due to the increased financial costs of fighting diarrhea. Research conducted in Rwanda to investigate the economic weight of children hospitalized with diarrhea reported that families typically carry the majority of the economic weight of hospitalization due to diarrhea and that this weight is significant, especially for families with minimal incomes [27]. In Kenya, it is estimated that rotavirus costs the healthcare system about $10.8 million per year. In a similar study carried out in Ghana in the healthcare sector to ascertain the cost of diarrhea [28], diarrhea-related expenses were reported to be high. In a study conducted in three Asian countries comprising of Bangladesh, India, and Pakistan to assess the household costs of pediatric diarrhea, the results suggest that diarrhea in children creates economic stress for the affected families [29]. 

Impact on the Health Sector

In addition, frequent episodes of diarrhea and the growing cost of treatment culminate in added liability for the already feeble health sector. In Kenya, there is a high cost of treatment for rotavirus gastroenteritis which contributes to the depletion of already low medical facilities [30]. Still, in Kenya, diarrheal infections caused 4,471 deaths, 8,781 hospital admissions, and 1,443,883 hospital appointments for diarrheal disease in children below 5 years old every year. In addition, diarrhea in children beneath the age of 5 can slow their development and lead to age-long disabilities. This report is supported by research conducted to assess the non-lethal impact of diarrhea in children, which reported that diarrhea considerably increases the likelihood of impaired physical growth and quality of development [31]. Regular episodes of diarrhea have also been shown to adversely disturb nutrient availability, physical growth, and mental capacity. Evidence abounds that suggests that pediatric diarrhea, especially during the first two years of life, can adversely disturb nutrient absorption culminating in reduced physical growth [32].

Factors Influencing Diarrhea in Children

Several factors affect the incidence of diarrhea in children. They are mainly classified as socioeconomic (maternal age, family size, employment level, and education status), environmental (drinking water sources and hygiene amenities), and behavior (artificial feeding and hand hygiene).

Environmental Factors

The prevalence of diarrhea in children is modulated by environmental factors such as drinking water sources, sanitation facilities, and water treatment. For example, drinking water from uncovered sources is remarkably linked with a greater risk of diarrhea [33]. The reason is not far-fetched, uncovered water sources are susceptible to contamination from runoff, making the water unsafe to drink. Mamboleo et al. [34] in their study in child care facilities using rainwater and shallow well water reported 86.7% of diarrheal cases in Kenya. Asfaha et al. [35] and Id et al. [33] in their studies discovered that the availability of toilets in families lowers diarrhea incidence in children in Ethiopia and Nigeria respectively. In a similar study piloted in Dale, Ethiopia, the risk of diarrhea in children under 5 years old was 3.23 times greater in children living in households with poor waste disposal compared to the risk of diarrhea in children living in households that properly dispose of waste [36]. Household waste contains many germs that can elicit diarrhea and is also a breeding ground for some flies. Therefore, improper waste disposal can increase the risk of exposure to waste- and food-borne disease-carrying insects, thereby depriving the entire household of sanitation and hygiene.

Inadequate clean drinking water and good hygiene represent the top causes of diarrhea, accounting for 72% and 56% of diarrheal deaths in infants under 5 years old, respectively [37]. 

The Sustainable Development Goal 6 (SDG-6) targets to accomplish fair global access to clean drinking water, and improved sanitary and hygiene infrastructures by the year 2030 [38]. Unfortunately, approximately 26% and 46% of the global population, respectively, did not have access to clean drinking water and improved sanitation infrastructures in 2020. It is predicted that billions of households will lack access to improved drinking water and improved sanitation facilities except incremental improvements are made by the year 2030 [39]. More so, there are remarkable inequalities in access to clean water and improved sanitation infrastructures between urban and rural areas. The availability of enhanced sanitation and clean drinking water infrastructures is diminished in rural settings compared to urban settings. Specifically, those with no improved water and sanitation facilities are more prevalent in rural areas, especially in developing regions, notably, Southern Asia and sub-Saharan Africa [40]. Worse still, in rural areas, only 2 in 10 people have sufficient portable drinking water [41]. Drinking water supply, sanitation, and diarrhea in children are interconnected. There are many documents justifying this fact [42-44]. Wolf et al. [44] reported that clean drinking water and proper sanitation facilities declined the risk of diarrhea by 52% and 24%, respectively, in low-income countries.

Socio-economic Factors

Maternal age, number of children, employment status, family size, and caregiver's education status are socioeconomic factors that influence the incidence of diarrhea in children under 5 years old. Several studies validate this fact. For example, a study in Pakistan has found that children of mothers or guardians with higher levels of education have much-reduced rates of diarrhea, regardless of clean water and sanitation facilities [45]. Educated mothers and caregivers have improved awareness about cleanliness and infant nourishment [46]. In related studies in Nepal, the incidence of childhood diarrhea was significantly lower in children whose mothers had secondary education than in children whose mothers had no education [47]. According to Demissie et al. [22] in a survey to determine the prevalence and variables associated with diarrhea in children under 5 years of age in 34 sub-Saharan African countries, the prevalence of diarrhea was higher in children with mothers who have a high school education or less. Educating women can improve their knowledge, attitudes, and practice of basic preventive measures such as appropriate breastfeeding, infant feeding, water treatment, and healthier child care [48].

The influence of the mother/caregiver's employment status on the incidence of diarrhea cannot be ignored. Research conducted by [46] in Pakistan shows that stay-at-home mothers have better diets than working mothers. Indeed, working mothers may have difficulty managing the time to prepare healthy meals and instead prefer to buy ready-made meals for their children, thereby weakening their immune systems, and leading to a higher risk of diarrhea and related diseases. According to Demissie et al. [22] in a survey to determine the prevalence and variables associated with diarrhea in children under 5 years of age in 34 sub-Saharan African countries, children of mothers who were currently working were at risk higher than that of mothers who do not work. A similar study in Ethiopia also reported similar trends [49].

According to Tareke et al. [50], children born to younger mothers have a greater risk of diarrhea than children born to older mothers (35-49 years old). There is no doubt that older mothers have better knowledge and experience about children's general health and diarrhea. Therefore, it is necessary to integrate education about diarrhea and other infectious diseases during antenatal care so that young mothers can be trained. The child's age and gender can also affect the incidence of diarrhea. Demissie et al. [22] reported an increased risk of developing diarrhea in children aged 12–23 years compared with children aged 0–11 months. This may be because babies between 12 and 23 months old start crawling and moving around the house and can therefore easily swallow dirty or contaminated items. This period is also the time when most children under 5 years old stop breastfeeding, so when they stop breastfeeding, babies will be exposed to germs from food and lose the ability to protect against infection. breast milk [51]. According to Tareke et al. [50] the increased risk of diarrhea in children older than 12 months of age may be due to the initiation of complementary feeding. Children who start taking complementary foods are at high risk of eating unhygienic food and are susceptible to diarrhea. This correlates with the results of a similar study conducted in Ethiopia [36].

Household income status affects diarrhea. Children from poor and middle-income households are at higher risk of diarrhea than children from rich households. The high risk of diarrhea in these groups of children may be explained by the difficult economic situation of parents or guardians, who cannot afford transportation costs to health centers and the prescribed drugs. In particular, poor children are malnourished, leading to reduced immunity and increased risk of diarrhea. Studies from Ghana [52], Tanzania [53], and Rwanda [54], all confirm an increased risk of diarrhea in low-income households. The inclusion of nutritional counseling has been pointed to play a remarkable improvement in the treatment results of diseases, especially those diseases whose severity escalates as a result of undernutrition [55]. The risk of diarrhea is higher in children under 5 years of age in households with 5 or more children under 5 years of age [Demissie et al. [22]. This may be because as the number of children under 5 years old in a household increase, the risk of exposure to germs and pathogens increases, and parental attention and quality of care decrease due to mothers are not capable of taking care of large numbers of children. This indicates that birth spacing may have a positive effect on preventing diarrhea. Therefore, this should be considered as one of the main interventions to reduce diarrhea-related morbidity and mortality in children under 5 years old. Asfaha et al. [35] in their study in Ethiopia, reported that children in households with more than three children under 5 years of age were four times more likely to have diarrhea than two or fewer children under 5 years of age in households.

Behavioral Factors

Caregiver behavioral factors, such as artificial feeding protocols and hand hygiene, influence the threat of diarrhea in infants. Despite the high prevalence of diarrhea among children in Kenya, Mamboleo et al. [34] in their study, reported that washing hands with soap after using the toilet reduced the incidence of diarrhea. Getu et al. [56] in their study in Ethiopia, reported that kids whose caregivers washed their hands with water only were two-fold at risk of having diarrhea compared with kids whose caregivers typically washed their hands with water and soap/ash. The vaccination status of children also affects the incidence of diarrhea. Connell and colleagues [53] in a research conducted in Rwanda, reported that children without rotavirus vaccination were eight times greater at risk of developing diarrhea than those who got vaccinated against rotavirus. House flooring materials have also been shown to have a significant influence on the occurrence of diarrhea in children. This is supported by a study conducted by Melese and colleagues [36] in the Dale district of Ethiopia. The study showed that the rate of diarrhea in children under 5 years old living in households without cement floors is 3.22 times higher than in children living in households with cement floors. The explanation for this could be that houses with cement floors are cleaner than non-cement floors. Child feeding practices are significantly correlated with diarrhea in children. Asfaha et al. [35], in a study conducted in the Zana district of Ethiopia, reported that infants who were not exclusively breastfed and those who received complementary feeding over 6 months of age were five times and twice, respectively, more likely to develop diarrhea, unlike other children of the same age. Similar results have been reported in East African countries [50] and Cameroon [57]. Demissie et al. [22] in a survey to determine the prevalence and variables associated with diarrhea in children under 5 years of age in 34 sub-Saharan African countries, reported that children who were initiated with breastfeeding within 1 hour of birth had a lower risk of diarrhea. Therefore, mothers should be encouraged to start breastfeeding within one hour so that their babies benefit from the protective effects of breastfeeding against infectious diseases, including diarrhea.

Strengthen Anti-Diarrhea Intervention Procedures

Mothers/Caregivers education and Breastfeeding

Educating the mother or guardian about child health care protocols, exclusive breastfeeding, and other attitudinal changes can help prevent diarrhea occurrence in children. Indeed, appropriate breastfeeding and the introduction of complementary feeding from 6 months provide defensive elements that can limit the emergence of infections, as well as diarrhea. It also strengthens children's immunity, indirectly reducing germs that accidentally enter complementary foods during feeding and due to inappropriate food processing, ingredients, and water used [35].
Although exclusive breastfeeding has several advantages, its application rate among infants under 6 months of age in developing nations is still low [58]. Hanieh et al. [59] in a prospective study conducted in Vietnam showed that exclusive breastfeeding at 6 weeks old remarkably lowered the risk of hospitalization due to diarrhea. A study conducted in nine African countries with high mortality due to diarrhea reported that kids who were breastfed immediately after birth and those on continuous exclusive breastfeeding till 6 months of age have a 20 and 50% lower risk of diarrhea, respectively [60]. Acharya et al. [47] reported that partial breastfeeding was linked with a 3.5-fold greater risk of diarrhea in infants compared with exclusive breastfeeding.
The protective effect of breast milk is due to the mother’s antibodies contained in breast milk. Among the obstacles to exclusive breastfeeding include type and location of childbirth, awareness of breast milk, problems associated with breastfeeding, mother's employment or educational level, and support for breastfeeding practices at home, community, and health facilities [61]. Therefore, educating mothers and communities about the benefits of breastfeeding as well as enhancing health systems to encourage breastfeeding practice can strengthen breastfeeding practices culminating in better maternal and child health.
Adequate education for mothers or caregivers similarly aids in lowering the incidence of diarrhea in children. Indeed, educated mothers or caregivers have good knowledge of individual and environmental hygiene protocols, infant feeding and care practices, maintaining standard living conditions, and good knowledge about measures to prevent and control diarrhea. Educated mothers or caregivers will have better waste disposal methods. Organizing public health education against diarrhea, focusing on increasing knowledge of treatments such as the use of oral rehydration (ORS) among rural populations is crucial. In fact, this approach has proven effective in the fight against HIV/AIDS [62]. Using religious leaders and communal health volunteers to improve the controlling of pediatric illnesses, including diarrhea, has presented reassuring effects in developing nations [63,64]

Proper Vaccination

Full vaccination will reduce rotavirus, a top root of diarrhea and loss of life in children under five years old [65]. Therefore, caregivers should be encouraged to vaccinate their children against rotavirus as this provides the best protection against pediatric diarrhea worldwide.
Rotarix and RotaTeq vaccines are linked with a remarkable reduction in hospitalization and death from rotavirus-associated diarrhea. Burnett et al. [66] in a review showed an overall reduction in hospitalization rates of 38% and 42% mortality rates caused by diarrhea in kids below age five. In the same study, rotavirus-related hospitalizations were reduced by 80%. In Botswana, vaccination coverage of 76 to 90% in kids below age 2 reduced diarrhea-orchestrated morbidity and mortality by approximately 23 and 22%, respectively [66]. According to Armah et al. [67], there was a 28 to 48

Conclusion

Numerous factors have been identified that affect the incidence of diarrhea in children. These include socioeconomic (mom’s/caregiver’s age, the number of kids, the caregiver’s occupation, the size of the household, and educational attainment), environmental (water source, and sanitation facilities), and behavior (artificial nourishing and hand hygiene). Factors that contribute to diarrhea can be minimized by educating mothers and caregivers about child health and care practices, appropriate breastfeeding, and other attitudinal changes that can help decrease the frequency of diarrhea in children. Notably, proper breastfeeding provides defensive elements that can limit the emergence of infections, as well as diarrhea. Breastfeeding also fortifies the baby's immune system and reduces the risk of germs that accidentally enter complementary foods during feeding due to improper preparation of foods, ingredients, and water. Furthermore, full vaccination reduces rotavirus, a foremost source of diarrheal disease and death in infants below the age of five. Appropriate nutritional measures are essential tools for controlling and treating diarrhea. Malnutrition exacerbates the incidence of diarrheal disease and makes it worse. It takes a collective effort by everyone to fight diarrhea in sub-Saharan Africa. Thus, let all hands be on the desk so as to achieve this feat.

References

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Tania Munoz

“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.

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George Varvatsoulias

Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.

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Rui Tao

Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.

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Khurram Arshad

Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.

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Gomez Barriga Maria Dolores

The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.

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Lin Shaw Chin

Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.

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Maria Dolores Gomez Barriga

Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.

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Dr Maria Dolores Gomez Barriga

Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.

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Dr Maria Regina Penchyna Nieto

Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.

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Dr Marcelo Flavio Gomes Jardim Filho

Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”

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Zsuzsanna Bene

Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner

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Dr Susan Weiner

My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.

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Lin-Show Chin

My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.

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Sonila Qirko

My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.

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Luiz Sellmann

I would like to offer my testimony in the support. I have received through the peer review process and support the editorial office where they are to support young authors like me, encourage them to publish their work in your esteemed journals, and globalize and share knowledge globally. I really appreciate your journal, peer review, and editorial office.

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Zhao Jia