AUCTORES
Globalize your Research
Research Article | DOI: https://doi.org/10.31579/2768-0487/064
Specialist general surgery and lecturer general surgery Dubai Medical College Dubai UAE.
*Corresponding Author: Aliya Ishaq, Specialist general surgery and lecturer general surgery Dubai Medical College Dubai UAE.
Citation: A Ishaq. (2021) Age Related Disparities in Colorectal Cancer Patients. Journal of Clinical and Laboratory Research. 3(3); DOI:10.31579/2768-0487/064
Copyright: ©2021 Aliya Ishaq. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Received: 24 July 2021 | Accepted: 04 September 2021 | Published: 10 September 2021
Keywords: colorectal cancer; right-sided colon; left-sided colon
Background:
There is an evident change in the colorectal cancer demographic over the period. This change is more marked in the age distribution and location of the tumor. It has practical implications, in regards to develop cancer awareness programs and screening protocols. Keeping in view that Pakistan is one of the countries with a high number of the young population this study is carried out to make a comparative analysis of this trend in our population.
Material and methods:
Colorectal cancer patients presented in Sindh Institute of urology and transplantation from January 2011 till December 2020 was reviewed retrospectively. All patients were divided into two groups, Group A young age population and Group B old age population. Subgroup analysis of study period was performed to check the progressive change in the trend of stage and clinical characteristics of colorectal cancer patients. Data reviewed from the patient’s files and collected as per Proforma requirement.
Result:
Total of 612 patients with colorectal cancer presented between 2011 till 2020.Among these patients 243 (39.7%) presented between January 2011 till December 2015. Patients age 50 years and younger were 410 (66.8%). Results showed a statistically significant association between and patient’s age and location of tumor such that left-sided colonic cancer and rectal cancer were more common in the young population. Subgroup analysis according to the study period showed that there is a change in the trend of disease presentation. Right-sided colonic cancer presentation decreased in the younger population over the period while simultaneously left-sided colonic cancer and rectal cancer presentation increased.
Conclusion:
The incidence of left-sided colonic and rectal cancer has been increased in the younger population over the specified period while there was no association between right-sided colon cancer and age noticed.
The demographics of Colorectal Cancer (CRC) are changing. The two aspects demonstrating the most remarkable change include the age distribution and location of the tumor in the large bowel. Overall, CRC is the most common malignancy of the gastrointestinal tract, the 3rd most common cancer, and the 4th leading cause of death by cancer [1, 2, 3]. With regards to the age distribution of CRC, between 2009 and 2013 colorectal cancer incidence decreased by 4.6% per year in individuals aged 65 years and older and increased in individuals younger than 50 years by 1.6% per year [1, 2, 3]. This decrease in incidence among individuals older than 55 years of age is largely attributed to population-based CRC screening recommendations in place since the 1980s [1, 2, 3, 4].
The increasing incidence among patients younger than 54 years of age also shows disparity related to location. So the incidence of rectal cancer has nearly quadrupled over the past few decades compared with colon cancer (41.5% v 9.8%, respectively) [1]. Subset analysis demonstrates an even finer-print regarding location-based incidence, among younger patients. So, for colon cancer, the adjusted incidence rates increased annually over roughly the past four decades by 2.4% in those aged 20 to 29 years, by 1.0% in those aged 30 to 39 years, and by 1.3% in those aged 40 to 49 years; for rectal cancer, the adjusted incidence rates have increased by 3.2% in those age 20-39 years and by 2.3% in those age 40-49 years [4].
Interestingly, the reduction in the incidence of colorectal cancer among older individuals, as explored earlier, is largely for distally located cancer, again demonstrating that the colorectal cancer incidence is also influenced by the location of tumor [1, 2, 3].
This changing epidemiology of CRC has practical implications, in particular for age to start screening. Recently, the US Preventive Services Task Force has recommended starting CRC screening at age 45 years instead of years [7]. However, previous studies have described a wide variation of this frequency worldwide, with the highest variance, found in the Asian population [1, 2]. Taking this into account and the dearth of related data in Pakistan, this study is being carried out to make a comparative analysis of these trends in CRC incidence in our population. This is particularly important because Pakistan has one of the youngest populations in the world, and with the increasing incidence of CRC in this age group, appropriate allocation of resources is warranted.
Despite informal observation by oncology professionals of shifting the age of onset of CRC to younger individuals and noting distinctive attributes of the disease in younger patients, few studies have formally documented this trend- even fewer in Pakistan. This practice-changing information needs more evidence to change attitudes and guidelines. This study is an effort in this regard.
1. To compare the proportion of diagnosed colorectal cancer between younger (less than and equal to 50 years) and older population (aged 51 years and above) over two consecutive periods spanning from January 2011- December 2015 and January 2016- December 2020.
2. To compare the proportional anatomical distribution of colorectal cancer between right-sided and left-sided tumors according to age group (younger and older, as defined above) over two consecutive periods spanning from January 2011- December 2015 and January 2016- December 2020.
A retrospective study was conducted in the Sindh Institute of urology and transplantation GI surgery department on patients diagnosed case of colorectal cancer. All patients received in Hanifa Suleiman Oncology center fulfilling inclusion criteria from January 2011 till December 2020 enrolled in the study. The clinical record of all patients was retrieved from the Hanifa Suleiman Oncology clinic registry, GI clinic patient’s registry, histopathology department, and hospital Record room. Variables mentioned in the questionnaire were all collected and stored with a given MR number maintaining data security and confidentiality. Approval for the study and exemption letter was obtained from Institutional Review Board (IRB) and ethical review committee (ERC). All variables mentioned in the questionnaire will be collected from the patient’s files including age, Gender, endoscopy (colonoscopy / Sigmoidoscopy) findings, Histological Type, Grade, Site of Tumor. For data analysis, all patients were divided into two groups, Group A young age population (age between 18-50 years) Group B old age population (age 51 years and 0nward). The young age population further subdivided into three groups, A1 (age 18-30 years), A2 (age 31-40 years), A3 (age 41-50 years) while the old age population also subdivided into three groups B1 (age 51-60 years), B2 (age 61-70 years) and B3 (age 71yeas onward). Subgroup analysis of study period (To check the progressive change in the trend of CRC in young patients) from January 2011 – December 2015 first period while from January 2016 – December 2020 second period. Subgroup analysis of study period (To check the progressive change in the trend of CRC in elder patients) from January 2011 – December 2015 first period while from January 2016 – December 2020 second period. Left-sided colonic Cancer includes cancer of descending Colon, distal 1/3rd of transverse Colon Cancer + sigmoid colon. Right-sided colonic Cancer includes cancers of ascending colon + proximal 2/3rd of transverse colon cancer. Rectal Cancer includes cancer anywhere from the rectosigmoid junction up to the anal verge.
All data collected were analyzed using SPSS version 23.0. Frequencies and percentages were computed for categorical variables while mean ± standard deviation for quantitative variables. Chi-square or Fisher’s Exact Test was used to determining the association between groups. An unadjusted odds ratio with a 95% confidence interval was employed to assess the direction and magnitude of association between variables. Significance based on p-value <0>
During this study period between 2011 till 2020, 612 patients presented with the diagnosis of colorectal cancer in our institute. Among these patients 243 (39.7%) presented between January 2011 till December 2015 while 369 (60.3%) presented between January 2016 till December 2020. Patients age 50 years and younger were 410 (66.8%) while 202 patients (32.2%) were 51 years or above. The mean age of patients at the time of presentation was 44.46+/- 15.36 years. Out of total 386 (63.1%) were male. At the time of initial presentation, 80 patients (13.1%) were diagnosed to have right colonic cancer, 96patients (15.7%) had left-sided colonic cancer and 436 patients (71.2%) had rectal cancer.
Results showed a statistically significant association between the patient’s age and the location of the tumor. Left-sided colonic cancer and rectal cancer were more common in the young age population 80.2 % and 66.7% as compared to the old age group 19.8% and 33.2% respectively. However, there is no statistical significance noted in right-sided colonic cancer between the two groups. Subgroup analysis based on age also showed similar results. When subgroup analysis is reviewed based on the study period results showed that there is a change in the trend of disease presentation. Right-sided colonic cancer decreased in the younger population over the period while simultaneously left-sided colonic cancer and rectal cancer increased with statistically significant results. On the other hand, no change in disease pattern was observed for right and left-sided colon cancer in the elderly population while rectal cancer presentation increased in the elderly age group over the period with a statistically significant P-Value.
Subgroup analyses based on age conclude that this change in the trend of disease, presentation is more marked between 31 till 60 years of age with statistically significant results.
Our study high lightened the fact that colorectal cancer incidence is increasing in the adult population over 10 years. We found that the incidence is shifted from 35% to 64.9% for left-sided colonic cancer while for rectal cancer the incidence is shifted from 37.2% to 62.6%. Almost similar results have been coated in other studies [4, 5, 6]. The American cancer society recommended starting screening for colorectal cancer at the age of 45 years because of the increased burden of disease in their young population. This change in screening age is based on the assumption that screening this age group may produce preventive effects due to early detection of disease and hence prompt management [7].
Our study results are similar to that of American data for colorectal cancer and even younger population 30 to 50 years age is at risk in Pakistan to develop colorectal cancer. Therefore considering screening endoscopy and at least Sigmoidoscopy for this population will be a great effort to diagnose the disease at an early stage with possibly better chances of treatment and long-term survival. However, there is no proper screening protocol for colorectal cancer in third world countries like Pakistan even for the old age population because of limited resources. For this reason, it is too early to use our data and support screening protocols in Pakistan but further studies on this issue are relevant which will help to monitor the trend of disease in the Pakistani population and to assess the need for adaptation of screening practice. Furthermore, we should study the underlying cause for colorectal cancer and identify the population at high risk and for the purpose first step is to make clinicians well aware of the fact that colorectal cancer is increasing in the young population quite rapidly and that sharp vigilance is needed in diagnosing the disease at the time of initial presentation. Awareness programs and dissemination of screening information for colorectal cancer have the potential to develop a better understanding of the signs and symptoms of the disease among the general population [3].
Our results support that screening endoscopy (colonoscopy/ Sigmoidoscopy) has preventive effects on colorectal cancer patients. Our study was also supported by the study conducted by Nancy et al who reported that Sigmoidoscopy reduces mortality in left-sided colon cancer in up to 70% of cases but because of inadequate coverage of the whole colon, it has no survival benefit in right-sided colon cancer cases. Based on these findings future trials involving colonoscopy versus Sigmoidoscopy for right and left-sided colonic cancer will certainly produce reliable risk prediction [1].
Our study has certain limitations, it is a retrospective study and hence the data has potential bias. Because of the retrospective nature of the study, we are unable to properly assess personal and family history and evaluate familial adenomatous polyposis syndrome. As this is a single-centered study with a limited number of cases, this study is not representing the true population as well as there is a lack of a national cancer registry. In this study, we only observe the trend of the disease over a specified period and are not able to address other associations. However, this study is among the first to give an overview of colorectal cancer incidence in the younger population of Pakistan. The major strength of the study is that it will develop colorectal cancer awareness and screening information in the general population. Hence we favor the development of awareness programs, screening protocols, and at least flexible Sigmoidoscopy screening in the young population given the predilection for left-sided cancers in this age group.
For all cancer sites combined, left-sided colonic and rectal cancer incidence increased in the younger population while no association between right-sided colon cancer and age was observed. Hence majors need to be taken in terms of awareness programs, screening protocols, and etiological research to elucidate causes for this trend which will help to reduce the number of colorectal cases in our young population.
Special thanks to Dr Muhammad Arsalan Khan Consultant HBP surgeon Sindh Institute of Urology and Transplantation for his valuable input regarding motivation and support for writing this article.
Nothing to disclose.
Clearly Auctoresonline and particularly Psychology and Mental Health Care Journal is dedicated to improving health care services for individuals and populations. The editorial boards' ability to efficiently recognize and share the global importance of health literacy with a variety of stakeholders. Auctoresonline publishing platform can be used to facilitate of optimal client-based services and should be added to health care professionals' repertoire of evidence-based health care resources.
Journal of Clinical Cardiology and Cardiovascular Intervention The submission and review process was adequate. However I think that the publication total value should have been enlightened in early fases. Thank you for all.
Journal of Women Health Care and Issues By the present mail, I want to say thank to you and tour colleagues for facilitating my published article. Specially thank you for the peer review process, support from the editorial office. I appreciate positively the quality of your journal.
Journal of Clinical Research and Reports I would be very delighted to submit my testimonial regarding the reviewer board and the editorial office. The reviewer board were accurate and helpful regarding any modifications for my manuscript. And the editorial office were very helpful and supportive in contacting and monitoring with any update and offering help. It was my pleasure to contribute with your promising Journal and I am looking forward for more collaboration.
We would like to thank the Journal of Thoracic Disease and Cardiothoracic Surgery because of the services they provided us for our articles. The peer-review process was done in a very excellent time manner, and the opinions of the reviewers helped us to improve our manuscript further. The editorial office had an outstanding correspondence with us and guided us in many ways. During a hard time of the pandemic that is affecting every one of us tremendously, the editorial office helped us make everything easier for publishing scientific work. Hope for a more scientific relationship with your Journal.
The peer-review process which consisted high quality queries on the paper. I did answer six reviewers’ questions and comments before the paper was accepted. The support from the editorial office is excellent.
Journal of Neuroscience and Neurological Surgery. I had the experience of publishing a research article recently. The whole process was simple from submission to publication. The reviewers made specific and valuable recommendations and corrections that improved the quality of my publication. I strongly recommend this Journal.
Dr. Katarzyna Byczkowska My testimonial covering: "The peer review process is quick and effective. The support from the editorial office is very professional and friendly. Quality of the Clinical Cardiology and Cardiovascular Interventions is scientific and publishes ground-breaking research on cardiology that is useful for other professionals in the field.
Thank you most sincerely, with regard to the support you have given in relation to the reviewing process and the processing of my article entitled "Large Cell Neuroendocrine Carcinoma of The Prostate Gland: A Review and Update" for publication in your esteemed Journal, Journal of Cancer Research and Cellular Therapeutics". The editorial team has been very supportive.
Testimony of Journal of Clinical Otorhinolaryngology: work with your Reviews has been a educational and constructive experience. The editorial office were very helpful and supportive. It was a pleasure to contribute to your Journal.
Dr. Bernard Terkimbi Utoo, I am happy to publish my scientific work in Journal of Women Health Care and Issues (JWHCI). The manuscript submission was seamless and peer review process was top notch. I was amazed that 4 reviewers worked on the manuscript which made it a highly technical, standard and excellent quality paper. I appreciate the format and consideration for the APC as well as the speed of publication. It is my pleasure to continue with this scientific relationship with the esteem JWHCI.
This is an acknowledgment for peer reviewers, editorial board of Journal of Clinical Research and Reports. They show a lot of consideration for us as publishers for our research article “Evaluation of the different factors associated with side effects of COVID-19 vaccination on medical students, Mutah university, Al-Karak, Jordan”, in a very professional and easy way. This journal is one of outstanding medical journal.
Dear Hao Jiang, to Journal of Nutrition and Food Processing We greatly appreciate the efficient, professional and rapid processing of our paper by your team. If there is anything else we should do, please do not hesitate to let us know. On behalf of my co-authors, we would like to express our great appreciation to editor and reviewers.
As an author who has recently published in the journal "Brain and Neurological Disorders". I am delighted to provide a testimonial on the peer review process, editorial office support, and the overall quality of the journal. The peer review process at Brain and Neurological Disorders is rigorous and meticulous, ensuring that only high-quality, evidence-based research is published. The reviewers are experts in their fields, and their comments and suggestions were constructive and helped improve the quality of my manuscript. The review process was timely and efficient, with clear communication from the editorial office at each stage. The support from the editorial office was exceptional throughout the entire process. The editorial staff was responsive, professional, and always willing to help. They provided valuable guidance on formatting, structure, and ethical considerations, making the submission process seamless. Moreover, they kept me informed about the status of my manuscript and provided timely updates, which made the process less stressful. The journal Brain and Neurological Disorders is of the highest quality, with a strong focus on publishing cutting-edge research in the field of neurology. The articles published in this journal are well-researched, rigorously peer-reviewed, and written by experts in the field. The journal maintains high standards, ensuring that readers are provided with the most up-to-date and reliable information on brain and neurological disorders. In conclusion, I had a wonderful experience publishing in Brain and Neurological Disorders. The peer review process was thorough, the editorial office provided exceptional support, and the journal's quality is second to none. I would highly recommend this journal to any researcher working in the field of neurology and brain disorders.
Dear Agrippa Hilda, Journal of Neuroscience and Neurological Surgery, Editorial Coordinator, I trust this message finds you well. I want to extend my appreciation for considering my article for publication in your esteemed journal. I am pleased to provide a testimonial regarding the peer review process and the support received from your editorial office. The peer review process for my paper was carried out in a highly professional and thorough manner. The feedback and comments provided by the authors were constructive and very useful in improving the quality of the manuscript. This rigorous assessment process undoubtedly contributes to the high standards maintained by your journal.
International Journal of Clinical Case Reports and Reviews. I strongly recommend to consider submitting your work to this high-quality journal. The support and availability of the Editorial staff is outstanding and the review process was both efficient and rigorous.
Thank you very much for publishing my Research Article titled “Comparing Treatment Outcome Of Allergic Rhinitis Patients After Using Fluticasone Nasal Spray And Nasal Douching" in the Journal of Clinical Otorhinolaryngology. As Medical Professionals we are immensely benefited from study of various informative Articles and Papers published in this high quality Journal. I look forward to enriching my knowledge by regular study of the Journal and contribute my future work in the field of ENT through the Journal for use by the medical fraternity. The support from the Editorial office was excellent and very prompt. I also welcome the comments received from the readers of my Research Article.
Dear Erica Kelsey, Editorial Coordinator of Cancer Research and Cellular Therapeutics Our team is very satisfied with the processing of our paper by your journal. That was fast, efficient, rigorous, but without unnecessary complications. We appreciated the very short time between the submission of the paper and its publication on line on your site.
I am very glad to say that the peer review process is very successful and fast and support from the Editorial Office. Therefore, I would like to continue our scientific relationship for a long time. And I especially thank you for your kindly attention towards my article. Have a good day!
"We recently published an article entitled “Influence of beta-Cyclodextrins upon the Degradation of Carbofuran Derivatives under Alkaline Conditions" in the Journal of “Pesticides and Biofertilizers” to show that the cyclodextrins protect the carbamates increasing their half-life time in the presence of basic conditions This will be very helpful to understand carbofuran behaviour in the analytical, agro-environmental and food areas. We greatly appreciated the interaction with the editor and the editorial team; we were particularly well accompanied during the course of the revision process, since all various steps towards publication were short and without delay".
I would like to express my gratitude towards you process of article review and submission. I found this to be very fair and expedient. Your follow up has been excellent. I have many publications in national and international journal and your process has been one of the best so far. Keep up the great work.
We are grateful for this opportunity to provide a glowing recommendation to the Journal of Psychiatry and Psychotherapy. We found that the editorial team were very supportive, helpful, kept us abreast of timelines and over all very professional in nature. The peer review process was rigorous, efficient and constructive that really enhanced our article submission. The experience with this journal remains one of our best ever and we look forward to providing future submissions in the near future.
I am very pleased to serve as EBM of the journal, I hope many years of my experience in stem cells can help the journal from one way or another. As we know, stem cells hold great potential for regenerative medicine, which are mostly used to promote the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. I think Stem Cell Research and Therapeutics International is a great platform to publish and share the understanding towards the biology and translational or clinical application of stem cells.
I would like to give my testimony in the support I have got by the peer review process and to support the editorial office where they were of asset to support young author like me to be encouraged to publish their work in your respected journal and globalize and share knowledge across the globe. I really give my great gratitude to your journal and the peer review including the editorial office.
I am delighted to publish our manuscript entitled "A Perspective on Cocaine Induced Stroke - Its Mechanisms and Management" in the Journal of Neuroscience and Neurological Surgery. The peer review process, support from the editorial office, and quality of the journal are excellent. The manuscripts published are of high quality and of excellent scientific value. I recommend this journal very much to colleagues.
Dr.Tania Muñoz, My experience as researcher and author of a review article in The Journal Clinical Cardiology and Interventions has been very enriching and stimulating. The editorial team is excellent, performs its work with absolute responsibility and delivery. They are proactive, dynamic and receptive to all proposals. Supporting at all times the vast universe of authors who choose them as an option for publication. The team of review specialists, members of the editorial board, are brilliant professionals, with remarkable performance in medical research and scientific methodology. Together they form a frontline team that consolidates the JCCI as a magnificent option for the publication and review of high-level medical articles and broad collective interest. I am honored to be able to share my review article and open to receive all your comments.
“The peer review process of JPMHC is quick and effective. Authors are benefited by good and professional reviewers with huge experience in the field of psychology and mental health. The support from the editorial office is very professional. People to contact to are friendly and happy to help and assist any query authors might have. Quality of the Journal is scientific and publishes ground-breaking research on mental health that is useful for other professionals in the field”.
Dear editorial department: On behalf of our team, I hereby certify the reliability and superiority of the International Journal of Clinical Case Reports and Reviews in the peer review process, editorial support, and journal quality. Firstly, the peer review process of the International Journal of Clinical Case Reports and Reviews is rigorous, fair, transparent, fast, and of high quality. The editorial department invites experts from relevant fields as anonymous reviewers to review all submitted manuscripts. These experts have rich academic backgrounds and experience, and can accurately evaluate the academic quality, originality, and suitability of manuscripts. The editorial department is committed to ensuring the rigor of the peer review process, while also making every effort to ensure a fast review cycle to meet the needs of authors and the academic community. Secondly, the editorial team of the International Journal of Clinical Case Reports and Reviews is composed of a group of senior scholars and professionals with rich experience and professional knowledge in related fields. The editorial department is committed to assisting authors in improving their manuscripts, ensuring their academic accuracy, clarity, and completeness. Editors actively collaborate with authors, providing useful suggestions and feedback to promote the improvement and development of the manuscript. We believe that the support of the editorial department is one of the key factors in ensuring the quality of the journal. Finally, the International Journal of Clinical Case Reports and Reviews is renowned for its high- quality articles and strict academic standards. The editorial department is committed to publishing innovative and academically valuable research results to promote the development and progress of related fields. The International Journal of Clinical Case Reports and Reviews is reasonably priced and ensures excellent service and quality ratio, allowing authors to obtain high-level academic publishing opportunities in an affordable manner. I hereby solemnly declare that the International Journal of Clinical Case Reports and Reviews has a high level of credibility and superiority in terms of peer review process, editorial support, reasonable fees, and journal quality. Sincerely, Rui Tao.
Clinical Cardiology and Cardiovascular Interventions I testity the covering of the peer review process, support from the editorial office, and quality of the journal.
Clinical Cardiology and Cardiovascular Interventions, we deeply appreciate the interest shown in our work and its publication. It has been a true pleasure to collaborate with you. The peer review process, as well as the support provided by the editorial office, have been exceptional, and the quality of the journal is very high, which was a determining factor in our decision to publish with you.
The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews journal clinically in the future time.
Clinical Cardiology and Cardiovascular Interventions, I would like to express my sincerest gratitude for the trust placed in our team for the publication in your journal. It has been a true pleasure to collaborate with you on this project. I am pleased to inform you that both the peer review process and the attention from the editorial coordination have been excellent. Your team has worked with dedication and professionalism to ensure that your publication meets the highest standards of quality. We are confident that this collaboration will result in mutual success, and we are eager to see the fruits of this shared effort.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
Dear Monica Gissare, - Editorial Coordinator of Nutrition and Food Processing. ¨My testimony with you is truly professional, with a positive response regarding the follow-up of the article and its review, you took into account my qualities and the importance of the topic¨.
Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.
My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.
My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.
I would like to offer my testimony in the support. I have received through the peer review process and support the editorial office where they are to support young authors like me, encourage them to publish their work in your esteemed journals, and globalize and share knowledge globally. I really appreciate your journal, peer review, and editorial office.
