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Review Article | DOI: https://doi.org/10.31579/2637-8892/346
*Corresponding Author: Hesham Maged Mohamed, Egyptian Ministry of health- Cairo University.
Citation: Hesham Maged Mohamed, (2025), A Clinical Review on Intellectual Disability, Psychology and Mental Health Care, 9(7): DOI:10.31579/2637-8892/346
Copyright: © 2025, Hesham Maged Mohamed. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received: 15 September 2025 | Accepted: 29 September 2025 | Published: 01 October 2025
Keywords: intellectual disability; mutation; genetic factors; chromosomal abnormality; down syndrome; cognitive function; physical ill health; lifespan.
About 2.3% of the population has an intellectual disability. The diagnosis of this disability is based on medical history, personal ability, and adaptive function. More than 75% of people with intellectual disability are classified as having mild intellectual disability, while a small percentage of people with severe symptoms are classified as having severe intellectual disability or profound intellectual disability. The specific cause of intellectual disability has not been identified, but genetics and heredity play a role. Complications before, during, or after birth also play a role. also mother's Substance abuse and alcohol intake during pregnancy play a role, physical ill health and disabilities are more common in people with intellectual disabilities, mental ill health is more common in children and adolescents and adults with intellectual disabilities. Also, people with intellectual disabilities don’t live as long as other people, and life expectancy is shorter than in general population.
At firstwe discussed the Prevalence of intellectual disabilities that not uncommon.A meta-analysis of 52 studies reported the prevalence of intellectual disabilities to be 10.37/1000 population [1] Prevalence varied according to age, incomegroup of the country of origin (with higher rates from low income countries), and study design. In high-income countries. rates for all ages combined were 9.2/1000, with the highest rates in child/young person populations only at 18.3/1000, and the lowest rates in adult-only populations at 4.9/1000. Careful understanding of the nuances is needed though to interpret these findings. Twenty-live of the studies included in the meta-analysis did not provide their age range: a further two did not report their observation period, and some studies were outliers in their findings. An earlier 1960 and 1987 is of lesser review of studies between relevance to today's population, given cohort effects, almost all were studies in childhood/youth, and some provided very limited meth-ideological information [2]. Studies of prevalence are, of course, challenging to conduct, as they ideally require intelligence to be tested on whole populations and therefore would considerable resources and costs. Otherapproaches can provideuseful information, for example: Studies of administrative samples, such as people known to local authorities, which account for the majority of studies. These are the people who are making demands upon services, so the information is useful, but there are likely to be some people with intellectual disabilities not included in these samples and some people who do not have intellectual disabilities within the sample. For ex-ample, a rate of 4.3/1,000 aged 16+ was reported from Welsh local authorities as being in receipt or in need of intellectual disabilities services [3].Studies of people with a record of intellectual disabilities in their general practitioner medical records. In high-income countries, people are likely to have been assessed once their developmental delay was reported, so a record is likely to exist. However, this is complicated by the multiple and changing terminology in use over time. For example, a rate of 5.4/1000patients aged 18+ was re-ported from an English database of 451 practices [4].Other secondary analysis of data routinely collected for other samples can be analyzed at relatively little costs, but findings refine purposes. Thesehave the attraction that large and wholecountry the originaldefinitions used and the ways the data were collected For example, a rate of 4.9/1000 aged 16+ (self-/proxy report) was reported from an analysis of Scotland's 2011 census 5, and a rate of 23/1000 school-aged children/young persons(teacher report was reported from Scotland's 2015 pupil census 6.Population intelligence approximates to a normal distribution with a mean intelligence quotient of 100 and a standard deviation of 15 points. A statistical definition of intellectual impairments is an intelligence quotient less than two standard deviations from the mean, that is, <70>
Causes and degreeof intellectual disabilities:
People with intellectual disabilities have some characteristics in common such as needing additional educational support at school, finding it hard to managemoney and bills without help as an adult, and having difficulties remembering the temporal sequencing of events. Every person with intellectual disabilities is also unique.
Each child inherits a range of genetic information from both their parents which is not shared with other children with intellectual. Identifying the cause of intellectual debilities is undertaken by pediatrician’s and clinical geneticists. There are four degrees of intellectual disability (Mild – Moderate – Severe – Profound)
Figure 1: Degrees Of Intellectual Disability
Genetic factors:
Genetic studies indicateintelligence is highlyheritable and can itself be conceptualized as a spectrum of syndromes (10). Additionally, there are many genetic causes of intellectual disabilities, and recent and ongoing studies have found numerous copy number variants associated with developmental disorders. genetic conditions include: Chromosomal anomalies, Examples are trisomy Down syndrome (trisomy 21). Palau’s syndrome (trisomy 13), Edwards syndrome (trisomy 15); autosomal deletions, for example, cri-du chat syndrome (terminal deletion of chromosome 15), Williams syndrome (deletion on chromosome 7), and Prader-Willi syndrome and Angelman's syndrome (deletion on chromosome 15 or uniparental disomy), and sex-linked conditions, for example,fragile X syndrome. Autosomal and sex linked recessive conditions (particularly in communities with high rates of consanguinity). Examples are phenylketonuria,homocystinuria, galactosaemia, lipid disorders- Tay-Sachs disease, Gaucher disease, Niemann-Pick disease; and mucopolysaccharidoses Hunter's disease and Hurler's disease.
Autosomal and sex-linked dominant conditions. Examplesin tuberous sclerosis and neurofibromatosis.
Regarding the prevalence of individual conditions in childhood: 1/800 has Down syndrome.
1/3600 boys and 1/4000-6000 girls have fragile-X syndrome. 1/7500 has Williams syndrome.
1/10,000 has Corneliade Lange.
1/10,000-25,000 has Prader-Willi syndrome. 1/15,000 has Angelman syndrome.
1/20.000 has Smith-Magenis syndrome. 1/50,000 has cri-du chat syndrome.
In addition to causing intellectual disabilities, physical condition’s, and influencing trajectories, these genetic conditions can cause a range of other cognitive, behavioural, and mental health problems, for which the term 'behavioural phenotype is used. Behavioural phenotypes have attracted particular research attention and can inform clinical assessments. Examples include high rates of dementia in middle-aged and older adults with Down syndrome (11, 12); affective psychosis in Prader-Willi syndrome (13, 14); self- injurious behavioral in Smith-Magnus syndrome [15]; and depression in phenylketonuria [16]. While these behavior’s/mentalill as interventions may help the individual. Additionally, some health are genetically driven, it is important to avoid therapeutic nihilism syndromes effect physiological differences, which influence treatment choices, for example, the low rates of heart disease and low blood Pressurein down syndrome differing immunology causing high rate of thyroid disorder and ther immunological disorders. 
Figure 2 :Two Main Of Id Etiologic GeneticFactors
Figure 3: Inheritance Of X-Linked Syndromal Intellectual Disability
Include, Teratogenic drugs and toxins. Examples include alcohol Infections. Examples includetoxoplasmosis, rubella, cytomegalo- virus, herpes simples, syphilis, zika virus, and other infections. Fetal growth retardation. Examplesinclude placental dysfunction and hypoxia Endocrine. Examples include iodine deficiency
Include: Birth injury, especially in premature and low-birthweight infants
Kernicterus, Infections, Postnatal factors,
Infections, encephalitis, Toxins, Brain tumor’s,Head injury, Starvation.
Extreme prematurity has been shown to accountfor 17% of cases of intellectual disabilities, together, gestational age and birthweight centile have been reported to account for 26.6% of intellectual dis- abilities [17]. The month of conception (January-March conception, compared with summer conception) has been reported to account for 15% of intellectual disabilities, postulated to be related to vitamin D or infections at the critical first trimester stage of development [18]. Fetal alcohol syndrome is underdiagnosed.
Two recent systematic reviews reported that mental ill health is more commonin children, young people, and adults with intellectual disabilities than in the general population (19, 20]. Problem behaviors, such as aggressive, self-injurious, and destructive behavior, are very common in people with intellectual disabilities and do not have an obvious comparator in the general population.Widely reported prevalence rates have been given in view of differences in populations studied (some from mental healthservices and so their rates are biased and inflated), methods used to identify mental ill health, the types of conditions included within the re- ported mental ill health (particularly whether or not problem be haviours and/or autism are included), the diagnostic criteria used whether studies are reporting point or life pre disorders,lation if strictly applied, especially for public CD-10 and DSM-5 under- report mental ill It is not surprising that mental ill health is more with intellectual disabilities, compared with the general population in view of complex biological factors, psychological and oral advantages, and additional developmental factors (22)Population-based studies in children and young people with intellectual disabilities reported the prevalence of mentality including problem behaviors, ranging from 30% (2324) [25]. A robust UK study reported a rate of 36% in 1 chi young people(aged 5-16 years) with intellectual disabilities com pared with 8% of 17.774 children without intellectual disabilities in the same survive the children and young people with intellectual disabilities accounted for 14% of all children with mental health (26).Population-based studies in adults with intellectual disabilities reported the prevalence of mental ill health, excluding problem be haviours, ranging from 14.5% (when also excluding ADHD, dementia, and personality disorder, people aged 65 and over, and people with severe intellectual disabilities (271) to 43.8%( with moderate to profound intellectual disabilities only [25] The largest adult population-based prevalence study, in whicheach person was individually assessed, included 1023 adults with im lectual disabilities [29]. It reported a point prevalence of mental health of 40.9%, or 28.3% excluding problem behavior’s, and more robust methods than previous smaller studies 130, 311 Some types of mental ill health are more common in people with intellectual disabilities, including schizophrenia [32, 33), bipolar disorder [34], dementia (particularly in adults with Down syndrome), but also in adults with intellectual disabilities of otheror unknown causes [35, 36], autism [26, 37, 38). ADHD [26], and pick with intellectual disabilities are reported to be higherthan for other children and young people for 27 out of 28 ICD-10 categories (26) Prevalence rates of mental ill health in children and young people Depression and anxiety are common in people with intellectual dis abilities, but probably not more so than in the general population [34,39].intellectual disabilities. In a large-scale, population-based study of Problem behaviorsare very common in the population with adults aged 16+ years, 22.5% were reported to have problem behaviors [29], and of those, 10% had aggressive behavior [40] and 5% had self-injurious behavior[41].The incidence of mental ill health in adults, excluding problem for psychotic disorders [42, 33). The incidence of dementia has also behaviors, has been reported to be 12.6% over a 2-year period-been reported for older adults with intellectual disabilities NOT 8.3% for affective disorders, 1.7% for anxiety disorders, and 1.4% due to Down syndrome and found to be considerably higher than for the age-matched general population. At the age of 65 years or older, the standardized incidence ratio for dementia was 4.98 [43]. Regarding problem behaviours, the 2-year incidence of aggression was reported as 1.8%, and of self-injury 0.6% [40, 41]. Full remission of psychosis after 2 years was only 14.3% [33], aggression 27.7%. incidences are higher than those found in the general population. much of the current high prevalence of mental ill health is due to and self-injury 38.2% [40, 41). These findings suggest that while incidence are higher than those found in the general population much of the current high prevalence of mental ill health is due to. Enduring disorders, rather than new episodes, though research on this is limited in quantity. longitudinal cohorts show high and enduringrates of depression Studieson common typesof mental ill health using general population and anxiety in adults with intellectual disabilities, compared with the general population [44-46]. Longitudinal studies have also reported on the mental ill health of children and young people with intellectual disabilities. In in Australian cohort study, children and young people aged 4-195 years were followedover four waves of data collection over 14 years. High rates of psychopathology levels were reported, with hyperactivity more prominent at younger ages and persisting for longer in children/young people with more severe degrees of intel- lectual disabilities. Emotional disorders emerged later in childhood [47-49]. Similar findings have been reported from longitudinal studies in children with intellectual disabilities/borderline intellectual disabilities (excluding those with more severeintellectual dis-abilities or with additional sensory or physical disabilities) in the Netherlands [50,51].
The term 'ESSENCE' (Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examination) to describe this [52]. He defined ESSENCE as major problems in: motor skills; general development; speech and language, social interaction and communication; behavior; hyperactivity or impulsivity; hypo activity, inattention; and sleep or feeding difficulties. Genetic data also increasingly support clustering of neurodevelopmental (including epilepsy) and mental health problems [53].
Additional physical ill health and disabilities are common in people with intellectual disabilities. Indeed multi-morbidity is typical for people with intellectual disabilities [4, 54], and hence too is polypharmacy. This has implications, as it adds complexity to mental and physical health assessments (for example, distinguishing be-tween complex partial seizures, depression, and anti-epileptic drug side effects), in assessments that are also challenging due to communication needs, impairment of understanding, and visual and hearing impairments, all of which are common in people with intellectual disabilities. This probably contributes to the under- recognition of mental ill health that occurs in this population. It also means that there are more disease-disease, drug-disease, and drug- drug inter-actions to take accountof when managing conditions. For example, postural problems and deformities (common in people with cerebral palsy and people with profound intellectual disabilities) impact upon gastro-oesophageal reflux disease (GORD), which is extremely common in people with intellectual disabilities, more so the more severe their intellectual disabilities, and can cause anxiety, GORDoccurs in about 50% of adults with intellectual disabilities, a con sequence is that drugs to manage osteoporosis cannot be tolerated, drugs, commonly prescribed for people with intellectual disabilities, and osteoporosis is common in this population. Many psychotropic lower the seizure threshold, and epilepsy is common. People with intellectual disabilities may not be able to self-report drug side effects is essential. Anticholinergic burden due to polypharmacy of drugs and are reliant on others observing these; hence, pharmacovigilance with theseside effects is an issuefor people with intellectual disabilities, with potential negative side effects such as further impairment of cognition [55]. Long-term conditions are more common for adults with intel-lectual disabilities, compared to the general population. Children, young people, and adults with intellectual disabilities have higher rates of epilepsy (25% (56]), visual impairment (50%), hearing impairment (40%), impacted cerumen, GORD (50% [57]), dysphagia [58], constipation, diabetes, thyroid dysfunction, osteoporosis, contractures, mobility and balance impairments, injuries, eczema, xerosis, obesity, and heart failure, compared with the general population [4, 54, 59, 60]. Asthma is also reported to be more common in people with intellectual disabilities and may be due to obesity, but it is possiblethat some of this is a misdiagnosis of reflux pneumonitis or aspiration pneumonia. In some cases, the excess physical ill health burden relates to the person'sunderlying cause of intellectual disabilities (for example, thyroid dysfunction and Down syndrome). but lifestyle and environmental factors and suboptimal support and health care are also important contributors. Some problems pre-dispose to others. For example, psychotropic drugs (prescribed to about 20% of the adult population with intellectual disabilities) [61] can increase diabetes risk, as can obesity which is common [62], and sedentary lifestyles, also common [63]). In view of the shorter life expectancy of people with more severe intellectual disabilities and those with syndromal causes for their intellectual disabilities, older adults with intellectual disabilities s have different characteristics, compared with younger adults. Older adults as a group have milder levels of intellectual disabilities and lesser quantities of additional physical ill health. The profile of their health needs changes, as they have lower rates of the physical ill health and disabilities associated with severe intellectual disabilities but start to acquire physical ill health associated with ageing. In extreme old age, the health characteristics of people with intellectual disabilities becomes more like those of the general population.
People with intellectual disabilities do not live as long as other people; and life expectancy is shorter, the more severe the person's intellectual disabilities. A recent systematic review included 27 studies and found that although life expectancy has improved in recent decades, it is lower,compared with the general population. by about 20 years,with no evidence of any closure of the inequality gap [64]. More severe intellectual disabilities and/or additional comorbidities were associated with the shortest life expectancy. Standardized mortality rates showed a greater inequality for women than for men, for reasons that are unknown. The main causes of death differed from the general population, with respiratory disease the most common, then circulatory diseases. greater congenital, and lesser ischemic, disease compared with the general population). Cancer was less common, compared with the general population, and the cancerprofile differed from that in the general population. Specific syndromes can also shorten life expectancy, including death in utere and in infancy and childhood. Life expectancy for people with Down syndrome has improved markedly over the last 50 years, with access to treatments for congenital heart disorders and improved surgical techniques and post-operative care accounting for much of this (65), but is still reported to be 30 years less than in the general population. Down syndrome has been reported to occur In 1.2/1000 pregnancies, of which 78.1% are live births. Survival at 1 year for live births in 1995-1999 was 91.6% [66], and 85% are estimated to survive to 10 years (67). The proportion of people with Down syndrome reduces in older cohorts, 75% survive to 50 years, 50% to 58.6 years, and 25% to 62.9 years [68].The shorter life expectancy of people with intellectual disabilities does not relate to syndromal causes of death and multi-morbidity. Some deaths are potentially avoidable, being amenable to good quality care. A confidential inquiry reviewed 247 deaths of people with intellectual disabilities, finding that 22% were aged less than 50 years (69). Avoidable deaths from causes that could have been amenable to good-quality health care occurred in 37%, com-pared with only 13% of the general population [69]. A further large-scale study (16,666 people with intellectual disabilities-656 deaths. compared with age, gender, and practice-matched controls,113,562- 1358 deaths) also found high rates of deaths amenable to good- quality health care at 37.0%, compared with 22.5% in the general population [70]. The authors also pointed out the standard definition of amenable deaths they used did not include some types of death that could be considered amenableto health care and which they found occurred more commonly in people with intellectual disabilities, including deaths from urinary tract infections and aspiration pneumonitis (70). Hence, these disturbing figures are actually an undercount of the deaths amenable to good care that people with intellectual disabilities experience. Improving health care for people with intellectual disabilities needs to become a priority for clinicians, service commissioners, and policymakers.
While a variety of studies focuson the multiple potential risk factors for intellectual disability, few have comprehensively examined the groups most at risk. Our review indicates that the risk is higher in cases of lower socioeconomic status, ethnicity, teenage motherhood, adolescent mental illness, and alcoholism. This highlights the target of desirable strategies. These include identifying and monitoring at- risk groups before, during, and after pregnancy, as well as the potential for new developmental disabilities in children, improved antenatal, perinatal, and neonatal health care, increased survival of very low-birthweight infants, identification and treatment of metabolic causes of intellectual disabilities like phenylketonuria, better childhood education, access to cardiac surgery for children with Down syndrome, improvedlifestyles, and accessto health care.
The authorsdeclare that there is no conflict of interest regarding the publication of this article. Funding/Support: This research did not receivegrants from any funding agency in the public and commercial sector.
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Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, I hope this message finds you well. I want to express my utmost gratitude for your excellent work and for the dedication and speed in the publication process of my article titled "Navigating Innovation: Qualitative Insights on Using Technology for Health Education in Acute Coronary Syndrome Patients." I am very satisfied with the peer review process, the support from the editorial office, and the quality of the journal. I hope we can maintain our scientific relationship in the long term.
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Dear Dr. Jessica Magne, Editorial Coordinator 0f Clinical Cardiology and Cardiovascular Interventions, The review process for the article “The Handling of Anti-aggregants and Anticoagulants in the Oncologic Heart Patient Submitted to Surgery” was extremely rigorous and detailed. From the initial submission to the final acceptance, the editorial team at the “Journal of Clinical Cardiology and Cardiovascular Interventions” demonstrated a high level of professionalism and dedication. The reviewers provided constructive and detailed feedback, which was essential for improving the quality of our work. Communication was always clear and efficient, ensuring that all our questions were promptly addressed. The quality of the “Journal of Clinical Cardiology and Cardiovascular Interventions” is undeniable. It is a peer-reviewed, open-access publication dedicated exclusively to disseminating high-quality research in the field of clinical cardiology and cardiovascular interventions. The journal's impact factor is currently under evaluation, and it is indexed in reputable databases, which further reinforces its credibility and relevance in the scientific field. I highly recommend this journal to researchers looking for a reputable platform to publish their studies.
Dear Editorial Coordinator of the Journal of Nutrition and Food Processing! "I would like to thank the Journal of Nutrition and Food Processing for including and publishing my article. The peer review process was very quick, movement and precise. The Editorial Board has done an extremely conscientious job with much help, valuable comments and advices. I find the journal very valuable from a professional point of view, thank you very much for allowing me to be part of it and I would like to participate in the future!”
Dealing with The Journal of Neurology and Neurological Surgery was very smooth and comprehensive. The office staff took time to address my needs and the response from editors and the office was prompt and fair. I certainly hope to publish with this journal again.Their professionalism is apparent and more than satisfactory. Susan Weiner
My Testimonial Covering as fellowing: Lin-Show Chin. The peer reviewers process is quick and effective, the supports from editorial office is excellent, the quality of journal is high. I would like to collabroate with Internatioanl journal of Clinical Case Reports and Reviews.
My experience publishing in Psychology and Mental Health Care was exceptional. The peer review process was rigorous and constructive, with reviewers providing valuable insights that helped enhance the quality of our work. The editorial team was highly supportive and responsive, making the submission process smooth and efficient. The journal's commitment to high standards and academic rigor makes it a respected platform for quality research. I am grateful for the opportunity to publish in such a reputable journal.
My experience publishing in International Journal of Clinical Case Reports and Reviews was exceptional. I Come forth to Provide a Testimonial Covering the Peer Review Process and the editorial office for the Professional and Impartial Evaluation of the Manuscript.
I would like to offer my testimony in the support. I have received through the peer review process and support the editorial office where they are to support young authors like me, encourage them to publish their work in your esteemed journals, and globalize and share knowledge globally. I really appreciate your journal, peer review, and editorial office.
Dear Agrippa Hilda- Editorial Coordinator of Journal of Neuroscience and Neurological Surgery, "The peer review process was very quick and of high quality, which can also be seen in the articles in the journal. The collaboration with the editorial office was very good."
I would like to express my sincere gratitude for the support and efficiency provided by the editorial office throughout the publication process of my article, “Delayed Vulvar Metastases from Rectal Carcinoma: A Case Report.” I greatly appreciate the assistance and guidance I received from your team, which made the entire process smooth and efficient. The peer review process was thorough and constructive, contributing to the overall quality of the final article. I am very grateful for the high level of professionalism and commitment shown by the editorial staff, and I look forward to maintaining a long-term collaboration with the International Journal of Clinical Case Reports and Reviews.
To Dear Erin Aust, I would like to express my heartfelt appreciation for the opportunity to have my work published in this esteemed journal. The entire publication process was smooth and well-organized, and I am extremely satisfied with the final result. The Editorial Team demonstrated the utmost professionalism, providing prompt and insightful feedback throughout the review process. Their clear communication and constructive suggestions were invaluable in enhancing my manuscript, and their meticulous attention to detail and dedication to quality are truly commendable. Additionally, the support from the Editorial Office was exceptional. From the initial submission to the final publication, I was guided through every step of the process with great care and professionalism. The team's responsiveness and assistance made the entire experience both easy and stress-free. I am also deeply impressed by the quality and reputation of the journal. It is an honor to have my research featured in such a respected publication, and I am confident that it will make a meaningful contribution to the field.
"I am grateful for the opportunity of contributing to [International Journal of Clinical Case Reports and Reviews] and for the rigorous review process that enhances the quality of research published in your esteemed journal. I sincerely appreciate the time and effort of your team who have dedicatedly helped me in improvising changes and modifying my manuscript. The insightful comments and constructive feedback provided have been invaluable in refining and strengthening my work".
I thank the ‘Journal of Clinical Research and Reports’ for accepting this article for publication. This is a rigorously peer reviewed journal which is on all major global scientific data bases. I note the review process was prompt, thorough and professionally critical. It gave us an insight into a number of important scientific/statistical issues. The review prompted us to review the relevant literature again and look at the limitations of the study. The peer reviewers were open, clear in the instructions and the editorial team was very prompt in their communication. This journal certainly publishes quality research articles. I would recommend the journal for any future publications.
Dear Jessica Magne, with gratitude for the joint work. Fast process of receiving and processing the submitted scientific materials in “Clinical Cardiology and Cardiovascular Interventions”. High level of competence of the editors with clear and correct recommendations and ideas for enriching the article.
We found the peer review process quick and positive in its input. The support from the editorial officer has been very agile, always with the intention of improving the article and taking into account our subsequent corrections.
My article, titled 'No Way Out of the Smartphone Epidemic Without Considering the Insights of Brain Research,' has been republished in the International Journal of Clinical Case Reports and Reviews. The review process was seamless and professional, with the editors being both friendly and supportive. I am deeply grateful for their efforts.
To Dear Erin Aust – Editorial Coordinator of Journal of General Medicine and Clinical Practice! I declare that I am absolutely satisfied with your work carried out with great competence in following the manuscript during the various stages from its receipt, during the revision process to the final acceptance for publication. Thank Prof. Elvira Farina
Dear Jessica, and the super professional team of the ‘Clinical Cardiology and Cardiovascular Interventions’ I am sincerely grateful to the coordinated work of the journal team for the no problem with the submission of my manuscript: “Cardiometabolic Disorders in A Pregnant Woman with Severe Preeclampsia on the Background of Morbid Obesity (Case Report).” The review process by 5 experts was fast, and the comments were professional, which made it more specific and academic, and the process of publication and presentation of the article was excellent. I recommend that my colleagues publish articles in this journal, and I am interested in further scientific cooperation. Sincerely and best wishes, Dr. Oleg Golyanovskiy.
Dear Ashley Rosa, Editorial Coordinator of the journal - Psychology and Mental Health Care. " The process of obtaining publication of my article in the Psychology and Mental Health Journal was positive in all areas. The peer review process resulted in a number of valuable comments, the editorial process was collaborative and timely, and the quality of this journal has been quickly noticed, resulting in alternative journals contacting me to publish with them." Warm regards, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. I appreciate the journal (JCCI) editorial office support, the entire team leads were always ready to help, not only on technical front but also on thorough process. Also, I should thank dear reviewers’ attention to detail and creative approach to teach me and bring new insights by their comments. Surely, more discussions and introduction of other hemodynamic devices would provide better prevention and management of shock states. Your efforts and dedication in presenting educational materials in this journal are commendable. Best wishes from, Farahnaz Fallahian.
Dear Maria Emerson, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. I am delighted to have published our manuscript, "Acute Colonic Pseudo-Obstruction (ACPO): A rare but serious complication following caesarean section." I want to thank the editorial team, especially Maria Emerson, for their prompt review of the manuscript, quick responses to queries, and overall support. Yours sincerely Dr. Victor Olagundoye.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. Many thanks for publishing this manuscript after I lost confidence the editors were most helpful, more than other journals Best wishes from, Susan Anne Smith, PhD. Australian Breastfeeding Association.
Dear Agrippa Hilda, Editorial Coordinator, Journal of Neuroscience and Neurological Surgery. The entire process including article submission, review, revision, and publication was extremely easy. The journal editor was prompt and helpful, and the reviewers contributed to the quality of the paper. Thank you so much! Eric Nussbaum, MD
Dr Hala Al Shaikh This is to acknowledge that the peer review process for the article ’ A Novel Gnrh1 Gene Mutation in Four Omani Male Siblings, Presentation and Management ’ sent to the International Journal of Clinical Case Reports and Reviews was quick and smooth. The editorial office was prompt with easy communication.
Dear Erin Aust, Editorial Coordinator, Journal of General Medicine and Clinical Practice. We are pleased to share our experience with the “Journal of General Medicine and Clinical Practice”, following the successful publication of our article. The peer review process was thorough and constructive, helping to improve the clarity and quality of the manuscript. We are especially thankful to Ms. Erin Aust, the Editorial Coordinator, for her prompt communication and continuous support throughout the process. Her professionalism ensured a smooth and efficient publication experience. The journal upholds high editorial standards, and we highly recommend it to fellow researchers seeking a credible platform for their work. Best wishes By, Dr. Rakhi Mishra.
Dear Jessica Magne, Editorial Coordinator, Clinical Cardiology and Cardiovascular Interventions, Auctores Publishing LLC. The peer review process of the journal of Clinical Cardiology and Cardiovascular Interventions was excellent and fast, as was the support of the editorial office and the quality of the journal. Kind regards Walter F. Riesen Prof. Dr. Dr. h.c. Walter F. Riesen.
Dear Ashley Rosa, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews, Auctores Publishing LLC. Thank you for publishing our article, Exploring Clozapine's Efficacy in Managing Aggression: A Multiple Single-Case Study in Forensic Psychiatry in the international journal of clinical case reports and reviews. We found the peer review process very professional and efficient. The comments were constructive, and the whole process was efficient. On behalf of the co-authors, I would like to thank you for publishing this article. With regards, Dr. Jelle R. Lettinga.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, I would like to express my deep admiration for the exceptional professionalism demonstrated by your journal. I am thoroughly impressed by the speed of the editorial process, the substantive and insightful reviews, and the meticulous preparation of the manuscript for publication. Additionally, I greatly appreciate the courteous and immediate responses from your editorial office to all my inquiries. Best Regards, Dariusz Ziora
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation, Auctores Publishing LLC, We would like to thank the editorial team for the smooth and high-quality communication leading up to the publication of our article in the Journal of Neurodegeneration and Neurorehabilitation. The reviewers have extensive knowledge in the field, and their relevant questions helped to add value to our publication. Kind regards, Dr. Ravi Shrivastava.
Dear Clarissa Eric, Editorial Coordinator, Journal of Clinical Case Reports and Studies, Auctores Publishing LLC, USA Office: +1-(302)-520-2644. I would like to express my sincere appreciation for the efficient and professional handling of my case report by the ‘Journal of Clinical Case Reports and Studies’. The peer review process was not only fast but also highly constructive—the reviewers’ comments were clear, relevant, and greatly helped me improve the quality and clarity of my manuscript. I also received excellent support from the editorial office throughout the process. Communication was smooth and timely, and I felt well guided at every stage, from submission to publication. The overall quality and rigor of the journal are truly commendable. I am pleased to have published my work with Journal of Clinical Case Reports and Studies, and I look forward to future opportunities for collaboration. Sincerely, Aline Tollet, UCLouvain.
Dear Ms. Mayra Duenas, Editorial Coordinator, International Journal of Clinical Case Reports and Reviews. “The International Journal of Clinical Case Reports and Reviews represented the “ideal house” to share with the research community a first experience with the use of the Simeox device for speech rehabilitation. High scientific reputation and attractive website communication were first determinants for the selection of this Journal, and the following submission process exceeded expectations: fast but highly professional peer review, great support by the editorial office, elegant graphic layout. Exactly what a dynamic research team - also composed by allied professionals - needs!" From, Chiara Beccaluva, PT - Italy.
Dear Maria Emerson, Editorial Coordinator, we have deeply appreciated the professionalism demonstrated by the International Journal of Clinical Case Reports and Reviews. The reviewers have extensive knowledge of our field and have been very efficient and fast in supporting the process. I am really looking forward to further collaboration. Thanks. Best regards, Dr. Claudio Ligresti
Dear Chrystine Mejia, Editorial Coordinator, Journal of Neurodegeneration and Neurorehabilitation. “The peer review process was efficient and constructive, and the editorial office provided excellent communication and support throughout. The journal ensures scientific rigor and high editorial standards, while also offering a smooth and timely publication process. We sincerely appreciate the work of the editorial team in facilitating the dissemination of innovative approaches such as the Bonori Method.” Best regards, Dr. Matteo Bonori.
I recommend without hesitation submitting relevant papers on medical decision making to the International Journal of Clinical Case Reports and Reviews. I am very grateful to the editorial staff. Maria Emerson was a pleasure to communicate with. The time from submission to publication was an extremely short 3 weeks. The editorial staff submitted the paper to three reviewers. Two of the reviewers commented positively on the value of publishing the paper. The editorial staff quickly recognized the third reviewer’s comments as an unjust attempt to reject the paper. I revised the paper as recommended by the first two reviewers.
Dear Maria Emerson, Editorial Coordinator, Journal of Clinical Research and Reports. Thank you for publishing our case report: "Clinical Case of Effective Fetal Stem Cells Treatment in a Patient with Autism Spectrum Disorder" within the "Journal of Clinical Research and Reports" being submitted by the team of EmCell doctors from Kyiv, Ukraine. We much appreciate a professional and transparent peer-review process from Auctores. All research Doctors are so grateful to your Editorial Office and Auctores Publishing support! I amiably wish our article publication maintained a top quality of your International Scientific Journal. My best wishes for a prosperity of the Journal of Clinical Research and Reports. Hope our scientific relationship and cooperation will remain long lasting. Thank you very much indeed. Kind regards, Dr. Andriy Sinelnyk Cell Therapy Center EmCell
Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. It was truly a rewarding experience to work with the journal “Clinical Cardiology and Cardiovascular Interventions”. The peer review process was insightful and encouraging, helping us refine our work to a higher standard. The editorial office offered exceptional support with prompt and thoughtful communication. I highly value the journal’s role in promoting scientific advancement and am honored to be part of it. Best regards, Meng-Jou Lee, MD, Department of Anesthesiology, National Taiwan University Hospital.
Dear Editorial Team, Journal-Clinical Cardiology and Cardiovascular Interventions, “Publishing my article with Clinical Cardiology and Cardiovascular Interventions has been a highly positive experience. The peer-review process was rigorous yet supportive, offering valuable feedback that strengthened my work. The editorial team demonstrated exceptional professionalism, prompt communication, and a genuine commitment to maintaining the highest scientific standards. I am very pleased with the publication quality and proud to be associated with such a reputable journal.” Warm regards, Dr. Mahmoud Kamal Moustafa Ahmed
Dear Maria Emerson, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews’, I appreciate the opportunity to publish my article with your journal. The editorial office provided clear communication during the submission and review process, and I found the overall experience professional and constructive. Best regards, Elena Salvatore.
Dear Mayra Duenas, Editorial Coordinator of ‘International Journal of Clinical Case Reports and Reviews Herewith I confirm an optimal peer review process and a great support of the editorial office of the present journal
Dear Editorial Team, Clinical Cardiology and Cardiovascular Interventions. I am really grateful for the peers review; their feedback gave me the opportunity to reflect on the message and impact of my work and to ameliorate the article. The editors did a great job in addition by encouraging me to continue with the process of publishing.
Dear Cecilia Lilly, Editorial Coordinator, Endocrinology and Disorders, Thank you so much for your quick response regarding reviewing and all process till publishing our manuscript entitled: Prevalence of Pre-Diabetes and its Associated Risk Factors Among Nile College Students, Sudan. Best regards, Dr Mamoun Magzoub.
International Journal of Clinical Case Reports and Reviews is a high quality journal that has a clear and concise submission process. The peer review process was comprehensive and constructive. Support from the editorial office was excellent, since the administrative staff were responsive. The journal provides a fast and timely publication timeline.
Dear Maria Emerson, Editorial Coordinator of International Journal of Clinical Case Reports and Reviews, What distinguishes International Journal of Clinical Case Report and Review is not only the scientific rigor of its publications, but the intellectual climate in which research is evaluated. The submission process is refreshingly free of unnecessary formal barriers and bureaucratic rituals that often complicate academic publishing without adding real value. The peer-review system is demanding yet constructive, guided by genuine scientific dialogue rather than hierarchical or authoritarian attitudes. Reviewers act as collaborators in improving the manuscript, not as gatekeepers imposing arbitrary standards. This journal offers a rare balance: high methodological standards combined with a respectful, transparent, and supportive editorial approach. In an era where publishing can feel more burdensome than research itself, this platform restores the original purpose of peer review — to refine ideas, not to obstruct them Prof. Perlat Kapisyzi, FCCP PULMONOLOGIST AND THORACIC IMAGING.
Dear Mayra Duenas, Editorial Coordinator of the journal IJCCR, I write here a little on my experience as an author submitting to the International Journal of Clinical Case Reports and Reviews (IJCCR). This was my first submission to IJCCR and my manuscript was inherently an outsider’s effort. It attempted to broadly identify and then make some sense of life’s under-appreciated mysteries. I initially had responded to a request for possible submissions. I then contacted IJCCR with a tentative topic for a manuscript. They quickly got back with an approval for the submission, but with a particular requirement that it be medically relevant. I then put together a manuscript and submitted it. After the usual back-and-forth over forms and formality, the manuscript was sent off for reviews. Within 2 weeks I got back 4 reviews which were both helpful and also surprising. Surprising in that the topic was somewhat foreign to medical literature. My subsequent updates in response to the reviewer comments went smoothly and in short order I had a series of proofs to evaluate. All in all, the whole publication process seemed outstanding. It was both helpful in terms of the paper’s content and also in terms of its efficient and friendly communications. Thank you all very much. Sincerely, Ted Christopher, Rochester, NY.
Dear Grace Pierce, Editorial Coordinator of the journal IJCCR, I had a very positive experience with Auctores - Journal throughout the publication process. The Editorial Team was highly responsive, professional, and supportive at every stage. I would like to extend my sincere thanks to the Editor: Grace Pierce, for her guidance and assistance. The peer-review process was smooth and constructive, helping improve the quality of my work. I would gladly recommend Auctores Journal to fellow researchers and authors. Dr. SABITA SINHA, Medical Oncologist, MD (Electro Homeopathy).
